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American Journal of Pathology, Vol 126, 452-463, Copyright © 1987 by American Society for Investigative Pathology

REGULAR ARTICLES

Tonsillar mapping of determinants found on normal lymphoreticular (T,B,K, immature and macrophage) and myeloblastic leukemia cells

EM McMillan, L Stoneking, GB Humphrey and J Rapacz

A monoclonal immunocytochemical method with 25 monoclonal antibodies was used to study the distribution in human tonsil of determinants expressed on T cells (mature and immature), Langerhans cells, B cells, killer/natural killer cells, macrophages, immature myeloid and lymphoblastic leukemia cells. Many of the respective determinants were found to have a discrete topographic distribution in normal reactive tonsil. The common acute lymphoblastic leukemia antigen and a determinant found on myeloblastic leukemia cells (My10) were not found in the specimens of the tonsil examined.




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Copyright © 1987 by the American Society for Investigative Pathology.