This Article Order Full text via Infotrieve Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Baskin, G. B. Search for Related Content PubMed PubMed Citation Articles by Baskin, G. B.

American Journal of Pathology, Vol 129, 345-352, Copyright © 1987 by American Society for Investigative Pathology

REGULAR ARTICLES

Disseminated cytomegalovirus infection in immunodeficient rhesus monkeys

GB Baskin
Department of Pathology, Delta Regional Primate Research Center, Tulane University, Covington, LA 70433.

Rhesus monkeys experimentally infected with the lentivirus SIV/Delta become immunodeficient and often die of opportunistic infections. The most frequent of these is cytomegalovirus (CMV). The lesions due to reactivated CMV infection in 14 SIV-infected monkeys were reviewed. Changes due to CMV were observed in the brain, lung, lymph node, liver, spleen, small intestine, testicle, nerves, and arteries. Disseminated CMV infection in immunodeficient rhesus monkeys is a useful model for studying the pathogenesis, treatment, and prevention of similar infections in immunodeficient human beings.

This article has been cited by other articles:

				D. A. Price, A. D. Bitmansour, J. B. Edgar, J. M. Walker, M. K. Axthelm, D. C. Douek, and L. J. Picker Induction and Evolution of Cytomegalovirus-Specific CD4+ T Cell Clonotypes in Rhesus Macaques J. Immunol., January 1, 2008; 180(1): 269 - 280. [Abstract] [Full Text] [PDF]

				L. E. Pereira, F. Villinger, H. Wulff, A. Sankaranarayanan, G. Raman, and A. A. Ansari Pharmacokinetics, Toxicity, and Functional Studies of the Selective Kv1.3 Channel Blocker 5-(4-Phenoxybutoxy)Psoralen in Rhesus Macaques Experimental Biology and Medicine, November 1, 2007; 232(10): 1338 - 1354. [Abstract] [Full Text] [PDF]

				P. Rivailler, A. Kaur, R. P. Johnson, and F. Wang Genomic sequence of rhesus cytomegalovirus 180.92: insights into the coding potential of rhesus cytomegalovirus. J. Virol., April 1, 2006; 80(8): 4179 - 4182. [Abstract] [Full Text] [PDF]

				E. H. Hutto, D. C. Anderson, and K. G. Mansfield Cytomegalovirus-associated Discrete Gastrointestinal Masses in Macaques Infected with the Simian Immunodeficiency Virus Vet. Pathol., November 1, 2004; 41(6): 691 - 695. [Abstract] [Full Text] [PDF]

				T. W. North, G. Sequar, L. B. Townsend, J. C. Drach, and P. A. Barry Rhesus Cytomegalovirus Is Similar to Human Cytomegalovirus in Susceptibility to Benzimidazole Nucleosides Antimicrob. Agents Chemother., July 1, 2004; 48(7): 2760 - 2765. [Abstract] [Full Text] [PDF]

				J. D. Reuter, D. L. Gomez, J. H. Wilson, and A. N. van den Pol Systemic Immune Deficiency Necessary for Cytomegalovirus Invasion of the Mature Brain J. Virol., February 1, 2004; 78(3): 1473 - 1487. [Abstract] [Full Text] [PDF]

				Y. Yue, S. S. Zhou, and P. A. Barry Antibody responses to rhesus cytomegalovirus glycoprotein B in naturally infected rhesus macaques J. Gen. Virol., December 1, 2003; 84(12): 3371 - 3379. [Abstract] [Full Text] [PDF]

				S. G. Hansen, L. I. Strelow, D. C. Franchi, D. G. Anders, and S. W. Wong Complete Sequence and Genomic Analysis of Rhesus Cytomegalovirus J. Virol., June 15, 2003; 77(12): 6620 - 6636. [Abstract] [Full Text] [PDF]

				W. L. W. Chang and P. A. Barry Cloning of the Full-Length Rhesus Cytomegalovirus Genome as an Infectious and Self-Excisable Bacterial Artificial Chromosome for Analysis of Viral Pathogenesis J. Virol., May 1, 2003; 77(9): 5073 - 5083. [Abstract] [Full Text] [PDF]

				A. Kaur, C. L. Hale, B. Noren, N. Kassis, M. A. Simon, and R. P. Johnson Decreased Frequency of Cytomegalovirus (CMV)-Specific CD4+ T Lymphocytes in Simian Immunodeficiency Virus-Infected Rhesus Macaques: Inverse Relationship with CMV Viremia J. Virol., March 19, 2002; 76(8): 3646 - 3658. [Abstract] [Full Text] [PDF]

				N. Dejucq and B. Jegou Viruses in the Mammalian Male Genital Tract and Their Effects on the Reproductive System Microbiol. Mol. Biol. Rev., June 1, 2001; 65(2): 208 - 231. [Abstract] [Full Text] [PDF]

				K. G. Mansfield, K.-C. Lin, J. Newman, D. Schauer, J. MacKey, A. A. Lackner, and A. Carville Identification of Enteropathogenic Escherichia coli in Simian Immunodeficiency Virus-Infected Infant and Adult Rhesus Macaques J. Clin. Microbiol., March 1, 2001; 39(3): 971 - 976. [Abstract] [Full Text]