help button home button Am J Pathol R & D Systems
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS

This Article
Right arrow Order Full text via Infotrieve
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gerdes, J.
Right arrow Articles by Flad, H. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gerdes, J.
Right arrow Articles by Flad, H. D.

American Journal of Pathology, Vol 138, 867-873, Copyright © 1991 by American Society for Investigative Pathology

REGULAR ARTICLES

Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67

J Gerdes, L Li, C Schlueter, M Duchrow, C Wohlenberg, C Gerlach, I Stahmer, S Kloth, E Brandt and HD Flad
Division of Molecular Immunology, Forschungsinstitut Borstel, Federal Republic of Germany.

The monoclonal antibody Ki-67 detects a human nuclear antigen that is present in proliferating cells, but absent in quiescent cells. The aim of this study was to characterize the Ki-67 antigen by means of immunobiochemical and molecular biology techniques. Enzymatic digestion experiments showed that this antigen is highly susceptible to protease treatment, and the antigen cannot be extracted by 0.1 normal HCl, indicating that Ki-67 antigen is a nonhistone protein. Immunoblot analysis of cell lysates with Ki-67 showed a double band with apparent molecular weights of 395 kd and 345 kd, regardless of whether the gels were run under reducing or nonreducing conditions. It is noteworthy that these bands were exclusively detectable in lysates prepared from proliferating cells, whereas they were absent in lysates obtained from quiescent cells. These immunobiochemical data are further substantiated by our molecular cloning approaches. By means of immunocloning with Ki- 67, the authors isolated and sequenced several cDNA fragments from lambda gt11 libraries. A 1095-bp fragment gave a strong hybridization signal at 7.5 to 9.5 kb in Northern blot analysis with RNA prepared from proliferating cells, whereas it was negative with RNA prepared from quiescent cells. This cDNA fragment could be bacterially expressed, and in subsequent immunoblot analysis Ki-67 reacted exclusively with those fusion proteins that were derived from bacteria containing the insert in the right reading frame.


This article has been cited by other articles:


Home page
 DevelopmentHome page
M. Screen, W. Dean, J. C. Cross, and M. Hemberger
Cathepsin proteases have distinct roles in trophoblast function and vascular remodelling
Development, October 1, 2008; 135(19): 3311 - 3320.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
M. Engman, L. Skoog, G. Soderqvist, and K. Gemzell-Danielsson
The effect of mifepristone on breast cell proliferation in premenopausal women evaluated through fine needle aspiration cytology
Hum. Reprod., September 1, 2008; 23(9): 2072 - 2079.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EndocrinolHome page
S Dubois, S Guyetant, P Menei, P Rodien, F Illouz, B Vielle, and V Rohmer
Relevance of Ki-67 and prognostic factors for recurrence/progression of gonadotropic adenomas after first surgery
Eur. J. Endocrinol., August 1, 2007; 157(2): 141 - 147.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. Kohwi, M. A. Petryniak, J. E. Long, M. Ekker, K. Obata, Y. Yanagawa, J. L. R. Rubenstein, and A. Alvarez-Buylla
A Subpopulation of Olfactory Bulb GABAergic Interneurons Is Derived from Emx1- and Dlx5/6-Expressing Progenitors
J. Neurosci., June 27, 2007; 27(26): 6878 - 6891.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
I. Zucchi, S. Sanzone, S. Astigiano, P. Pelucchi, M. Scotti, V. Valsecchi, O. Barbieri, G. Bertoli, A. Albertini, R. A. Reinbold, et al.
The properties of a mammary gland cancer stem cell
PNAS, June 19, 2007; 104(25): 10476 - 10481.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
H. Zang, L. Sahlin, B. Masironi, E. Eriksson, and A. Linden Hirschberg
Effects of Testosterone Treatment on Endometrial Proliferation in Postmenopausal Women
J. Clin. Endocrinol. Metab., June 1, 2007; 92(6): 2169 - 2175.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
M. Bogunovic, F. Ginhoux, A. Wagers, M. Loubeau, L. M. Isola, L. Lubrano, V. Najfeld, R. G. Phelps, C. Grosskreutz, E. Scigliano, et al.
Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men
J. Exp. Med., November 27, 2006; 203(12): 2627 - 2638.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
H. Si, S. C. Verma, and E. S. Robertson
Proteomic Analysis of the Kaposi's Sarcoma-Associated Herpesvirus Terminal Repeat Element Binding Proteins.
J. Virol., September 1, 2006; 80(18): 9017 - 9030.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
D. M. Nguyen, K. Sam, A. Tsimelzon, X. Li, H. Wong, S. Mohsin, G. M. Clark, S. G. Hilsenbeck, R. M. Elledge, D. C. Allred, et al.
Molecular Heterogeneity of Inflammatory Breast Cancer: A Hyperproliferative Phenotype
Clin. Cancer Res., September 1, 2006; 12(17): 5047 - 5054.
[Abstract] [Full Text] [PDF]

Home page
 INT J SURG PATHOLHome page
A. Righi, C. M. Betts, C. Marchetti, G. Marucci, L. Montebugnoli, C. Prati, L. H. U. Eusebi, L. Muzzi, T. Ragazzini, and M. P. Foschini
Merkel cells in the oral mucosa.
International Journal of Surgical Pathology, July 1, 2006; 14(3): 206 - 211.
[Abstract] [PDF]

Home page
 JCOHome page
A. Urruticoechea, I. E. Smith, and M. Dowsett
Proliferation Marker Ki-67 in Early Breast Cancer
J. Clin. Oncol., October 1, 2005; 23(28): 7212 - 7220.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
A. Petiot, C. L. Perriton, C. Dickson, and M. J. Cohn
Development of the mammalian urethra is controlled by Fgfr2-IIIb
Development, May 15, 2005; 132(10): 2441 - 2450.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
C. E.T. da Costa, N. E. Annels, C. M.J.M. Faaij, R. G. Forsyth, P. C.W. Hogendoorn, and R. M. Egeler
Presence of osteoclast-like multinucleated giant cells in the bone and nonostotic lesions of Langerhans cell histiocytosis
J. Exp. Med., March 7, 2005; 201(5): 687 - 693.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
R. S. Levinson, E. Batourina, C. Choi, M. Vorontchikhina, J. Kitajewski, and C. L. Mendelsohn
Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development
Development, February 1, 2005; 132(3): 529 - 539.
[Abstract] [Full Text] [PDF]

Home page
 JBJSHome page
H.-G. Willert, G. H. Buchhorn, A. Fayyazi, R. Flury, M. Windler, G. Koster, and C. H. Lohmann
Metal-on-Metal Bearings and Hypersensitivity in Patients with Artificial Hip Joints. A Clinical and Histomorphological Study
J. Bone Joint Surg. Am., January 1, 2005; 87(1): 28 - 36.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
J. Holmberg, C.-Y. Liu, and T. A. Hjalt
PITX2 Gain-of-Function in Rieger Syndrome Eye Model
Am. J. Pathol., November 1, 2004; 165(5): 1633 - 1641.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
X. Guo, A. E. K. Hutcheon, and J. D. Zieske
TAT-Mediated Protein Transduction into Human Corneal Epithelial Cells: p15INK4b Inhibits Cell Proliferation and Stimulates Cell Migration
Invest. Ophthalmol. Vis. Sci., June 1, 2004; 45(6): 1804 - 1811.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
T. Cheutin, M.-F. O'Donohue, A. Beorchia, C. Klein, H. Kaplan, and D. Ploton
Three-dimensional Organization of pKi-67: A Comparative Fluorescence and Electron Tomography Study Using Fluoronanogold
J. Histochem. Cytochem., November 1, 2003; 51(11): 1411 - 1423.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
Y. Haga, K. Hiroshima, A. Iyoda, K. Shibuya, F. Shimamura, T. Iizasa, T. Fujisawa, and H. Ohwada
Ki-67 expression and prognosis for smokers with resected stage i Non-Small cell lung cancer
Ann. Thorac. Surg., June 1, 2003; 75(6): 1727 - 1732.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
T. C. Polek, L. V. Stewart, E. J. Ryu, M. B. Cohen, E. A. Allegretto, and N. L. Weigel
p53 Is Required for 1,25-Dihydroxyvitamin D3-Induced G0 Arrest But Is Not Required for G1 Accumulation or Apoptosis of LNCaP Prostate Cancer Cells
Endocrinology, January 1, 2003; 144(1): 50 - 60.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
M. Krejca, J. Skarysz, P. Szmagala, D. Plewka, G. Nowaczyk, A. Plewka, and A. Bochenek
A new outside stent - does it prevent vein graft intimal proliferation?
Eur. J. Cardiothorac. Surg., December 1, 2002; 22(6): 898 - 903.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
P. A. Burke, S. J. DeNardo, L. A. Miers, K. R. Lamborn, S. Matzku, and G. L. DeNardo
Cilengitide Targeting of {alpha}v{beta}3 Integrin Receptor Synergizes with Radioimmunotherapy to Increase Efficacy and Apoptosis in Breast Cancer Xenografts
Cancer Res., August 1, 2002; 62(15): 4263 - 4272.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
C. Indolfi, D. Torella, C. Coppola, E. Stabile, G. Esposito, A. Curcio, A. Pisani, L. Cavuto, O. Arcucci, M. Cireddu, et al.
Rat carotid artery dilation by PTCA balloon catheter induces neointima formation in presence of IEL rupture
Am J Physiol Heart Circ Physiol, August 1, 2002; 283(2): H760 - H767.
[Abstract] [Full Text] [PDF]

Home page
 JCOHome page
A. Stojadinovic, R. A. Ghossein, A. Hoos, A. Nissan, D. Marshall, M. Dudas, C. Cordon-Cardo, D. P. Jaques, and M. F. Brennan
Adrenocortical Carcinoma: Clinical, Morphologic, and Molecular Characterization
J. Clin. Oncol., February 15, 2002; 20(4): 941 - 950.
[Abstract] [Full Text] [PDF]

Home page
 Vet PatholHome page
F. Millanta, G. Lazzeri, M. Mazzei, I. Vannozzi, and A. Poli
MIB-1 Labeling Index in Feline Dysplastic and Neoplastic Mammary Lesions and Its Relationship with Postsurgical Prognosis
Vet. Pathol., January 1, 2002; 39(1): 120 - 126.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
A. Hoos, A. Stojadinovic, B. Singh, M. E. Dudas, D. H. Y. Leung, A. R. Shaha, J. P. Shah, M. F. Brennan, C. Cordon-Cardo, and R. Ghossein
Clinical Significance of Molecular Expression Profiles of Hurthle Cell Tumors of the Thyroid Gland Analyzed via Tissue Microarrays
Am. J. Pathol., January 1, 2002; 160(1): 175 - 183.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
M. Krams, A. Claviez, K. Heidorn, G. Krupp, R. Parwaresch, D. Harms, and P. Rudolph
Regulation of Telomerase Activity by Alternate Splicing of Human Telomerase Reverse Transcriptase mRNA in a Subset of Neuroblastomas
Am. J. Pathol., November 1, 2001; 159(5): 1925 - 1932.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
C. L. Chaffin, K. M. Schwinof, and R. L. Stouffer
Gonadotropin and Steroid Control of Granulosa Cell Proliferation During the Periovulatory Interval in Rhesus Monkeys
Biol Reprod, September 1, 2001; 65(3): 755 - 762.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
J. Anderson, A. Ramsay, S. Gould, and K. Pritchard-Jones
PAX3-FKHR Induces Morphological Change and Enhances Cellular Proliferation and Invasion in Rhabdomyosarcoma
Am. J. Pathol., September 1, 2001; 159(3): 1089 - 1096.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Pathol.Home page
T Watanabe, Y Oda, S Tamiya, K Masuda, and M Tsuneyoshi
Malignant peripheral nerve sheath tumour arising within neurofibroma. An immunohistochemical analysis in the comparison between benign and malignant components
J. Clin. Pathol., August 1, 2001; 54(8): 631 - 636.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
J. A. Winston, L. A. Bruggeman, M. D. Ross, J. Jacobson, L. Ross, V. D. D'Agati, P. E. Klotman, and M. E. Klotman
Nephropathy and Establishment of a Renal Reservoir of HIV Type 1 during Primary Infection
N. Engl. J. Med., June 28, 2001; 344(26): 1979 - 1984.
[Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
P. Birner, M. Ritzi, C. Musahl, R. Knippers, J. Gerdes, T. Voigtlander, H. Budka, and J. A. Hainfellner
Immunohistochemical Detection of Cell Growth Fraction in Formalin-Fixed and Paraffin-Embedded Murine Tissue
Am. J. Pathol., June 1, 2001; 158(6): 1991 - 1996.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
J. ZHOU, S. NG, O. ADESANYA-FAMUIYA, K. ANDERSON, and C. A. BONDY
Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression
FASEB J, September 1, 2000; 14(12): 1725 - 1730.
[Abstract] [Full Text]

Home page
 Mol. Cell. Biol.Home page
L. J. Wood, M. Mukherjee, C. E. Dolde, Y. Xu, J. F. Maher, T. E. Bunton, J. B. Williams, and L. M. S. Resar
HMG-I/Y, a New c-Myc Target Gene and Potential Oncogene
Mol. Cell. Biol., August 1, 2000; 20(15): 5490 - 5502.
[Abstract] [Full Text]

Home page
 Cancer Epidemiol. Biomarkers Prev.Home page
S. Y. Zhang, S. C. Liu, L. F. Al-Saleem, D. Holloran, J. Babb, X. Guo, and A. J. P. Klein-Szanto
E2F-1: A Proliferative Marker of Breast Neoplasia
Cancer Epidemiol. Biomarkers Prev., April 1, 2000; 9(4): 395 - 401.
[Abstract] [Full Text]

Home page
 Clin. Cancer Res.Home page
A. L. Folpe, R. H. Lyles, J. T. Sprouse, E. U. Conrad III, and J. F. Eary
(F-18) Fluorodeoxyglucose Positron Emission Tomography as a Predictor of Pathologic Grade and Other Prognostic Variables in Bone and Soft Tissue Sarcoma
Clin. Cancer Res., April 1, 2000; 6(4): 1279 - 1287.
[Abstract] [Full Text]

Home page
 CirculationHome page
L. J. Feldman, L. Aguirre, M. Ziol, J.-P. Bridou, N. Nevo, J.-B. Michel, and P. G. Steg
Interleukin-10 Inhibits Intimal Hyperplasia After Angioplasty or Stent Implantation in Hypercholesterolemic Rabbits
Circulation, February 29, 2000; 101(8): 908 - 916.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
M. D. Hazenberg, J. W. T. C. Stuart, S. A. Otto, J. C. C. Borleffs, C. A. B. Boucher, R. J. de Boer, F. Miedema, and D. Hamann
T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART)
Blood, January 1, 2000; 95(1): 249 - 255.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
C Ihling, T Szombathy, K Nampoothiri, J Haendeler, F Beyersdorf, M Uhl, A M Zeiher, and H E Schaefer
Cystic medial degeneration of the aorta is associated with p53 accumulation, Bax upregulation, apoptotic cell death, and cell proliferation
Heart, September 1, 1999; 82(3): 286 - 293.
[Abstract] [Full Text] [PDF]

Home page
 JCOHome page
A. D. Thor, S. Liu, D. H. Moore II, and S. M. Edgerton
Comparison of Mitotic Index, In Vitro Bromodeoxyuridine Labeling, and MIB-1 Assays to Quantitate Proliferation in Breast Cancer
J. Clin. Oncol., February 1, 1999; 17(2): 470 - 470.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
E. Lutgens, E. D. de Muinck, P. J.E.H.M. Kitslaar, J. H.M. Tordoir, H. J.J. Wellens, and M. J.A.P. Daemen
Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques
Cardiovasc Res, February 1, 1999; 41(2): 473 - 479.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
H Tseng, J. Biegel, and R. Brown
Basonuclin is associated with the ribosomal RNA genes on human keratinocyte mitotic chromosomes
J. Cell Sci., January 9, 1999; 112(18): 3039 - 3047.
[Abstract] [PDF]

Home page
 Arch OphthalmolHome page
J. S. Pollack, J. E. Kim, J. S. Pulido, and J. M. Burke
Tissue Effects of Subclinical Diode Laser Treatment of the Retina
Arch Ophthalmol, December 1, 1998; 116(12): 1633 - 1639.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
A. Herrler, C. A. Krusche, and H. M. Beier
Insulin and Insulin-like Growth Factor-I Promote Rabbit Blastocyst Development and Prevent Apoptosis
Biol Reprod, December 1, 1998; 59(6): 1302 - 1310.
[Abstract] [Full Text]

Home page
 Reproductive SciencesHome page
S. C. Smith, E. Price, M. J. Hewitt, E. M. Symonds, and P. N. Baker
Cellular Proliferation in the Placenta in Normal Human Pregnancy and Pregnancy Complicated by Intrauterine Growth Restriction
Reproductive Sciences, November 1, 1998; 5(6): 317 - 323.
[Abstract] [PDF]

Home page
 Am. J. Pathol.Home page
M. Nagata, K.-i. Nakayama, Y. Terada, S. Hoshi, and T. Watanabe
Cell Cycle Regulation and Differentiation in the Human Podocyte Lineage
Am. J. Pathol., November 1, 1998; 153(5): 1511 - 1520.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
K. J. Luzzi, I. C. MacDonald, E. E. Schmidt, N. Kerkvliet, V. L. Morris, A. F. Chambers, and A. C. Groom
Multistep Nature of Metastatic Inefficiency : Dormancy of Solitary Cells after Successful Extravasation andLimited Survival of Early Micrometastases
Am. J. Pathol., September 1, 1998; 153(3): 865 - 873.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
H. Kawana, J.-i. Tamaru, T. Tanaka, A. Hirai, Y. Saito, M. Kitagawa, A. Mikata, K. Harigaya, and T. Kuriyama
Role of p27Kip1 and Cyclin-Dependent Kinase 2 in the Proliferation of Non-Small Cell Lung Cancer
Am. J. Pathol., August 1, 1998; 153(2): 505 - 513.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
M&; G. Mahoney, W. Tang, M. M. Xiang, S. B. Moss, G. L. Gerton, J. R. Stanley, and H. Tseng
Translocation of the Zinc Finger Protein Basonuclin from the Mouse Germ Cell Nucleus to the Midpiece of the Spermatozoon during Spermiogenesis
Biol Reprod, August 1, 1998; 59(2): 388 - 394.
[Abstract] [Full Text]

Home page
 J. Clin. Endocrinol. Metab.Home page
S. J. Weil, K. Vendola, J. Zhou, O. O. Adesanya, J. Wang, J. Okafor, and C. A. Bondy
Androgen Receptor Gene Expression in the Primate Ovary: Cellular Localization, Regulation, and Functional Correlations
J. Clin. Endocrinol. Metab., July 1, 1998; 83(7): 2479 - 2485.
[Abstract] [Full Text]

Home page
 J. Clin. Endocrinol. Metab.Home page
T. Mizutani, A. Sugihara, K. Nakamuro, and N. Terada
Suppression of Cell Proliferation and Induction of Apoptosis in Uterine Leiomyoma by Gonadotropin-Releasing Hormone Agonist (Leuprolide Acetate)
J. Clin. Endocrinol. Metab., April 1, 1998; 83(4): 1253 - 1255.
[Abstract] [Full Text]

Home page
 Circ. Res.Home page
F. C. Tanner, Z.-Y. Yang, E. Duckers, D. Gordon, G. J. Nabel, and E. G. Nabel
Expression of Cyclin-Dependent Kinase Inhibitors in Vascular Disease
Circ. Res., February 23, 1998; 82(3): 396 - 403.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
R. Brandl, T. Richter, K. Haug, M. G. Wilhelm, P. C. Maurer, and W. Nathrath
Topographic Analysis of Proliferative Activity in Carotid Endarterectomy Specimens by Immunocytochemical Detection of the Cell Cycle–Related Antigen Ki-67
Circulation, November 18, 1997; 96(10): 3360 - 3368.
[Abstract] [Full Text]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
C. Ihling, G. Menzel, E. Wellens, J. S. Monting, H. E. Schaefer, and A. M. Zeiher
Topographical Association Between the Cyclin-Dependent Kinases Inhibitor P21, p53 Accumulation, and Cellular Proliferation in Human Atherosclerotic Tissue
Arterioscler. Thromb. Vasc. Biol., October 1, 1997; 17(10): 2218 - 2224.
[Abstract] [Full Text]

Home page
 INT J SURG PATHOLHome page
M. J. Costa, J. Walls, A. Dickerman, P. F. Ames, L. M. Roth, and D. Guinee Jr
Cell Cycle Control of Ovarian Granulosa Cells in Tumors and Cysts
International Journal of Surgical Pathology, October 1, 1996; 4(2): 61 - 69.
[Abstract] [PDF]

Home page
 J. Cell Sci.Home page
I. Kill
Localisation of the Ki-67 antigen within the nucleolus. Evidence for a fibrillarin-deficient region of the dense fibrillar component
J. Cell Sci., January 6, 1996; 109(6): 1253 - 1263.
[Abstract] [PDF]

Home page
 J. Cell Sci.Home page
M Starborg, K Gell, E Brundell, and C Hoog
The murine Ki-67 cell proliferation antigen accumulates in the nucleolar and heterochromatic regions of interphase cells and at the periphery of the mitotic chromosomes in a process essential for cell cycle progression
J. Cell Sci., January 1, 1996; 109(1): 143 - 153.
[Abstract] [PDF]

Home page
 INT J SURG PATHOLHome page
F. C. Schmitt and M. P. Ferreira
MIB-1 Is a Suitable Marker of Proliferative Activity in Formalin-fixed, Paraffin-embedded Sections of Breast Cancer
International Journal of Surgical Pathology, April 1, 1995; 2(4): 287 - 293.
[Abstract] [PDF]

Home page
 INT J SURG PATHOLHome page
L. M. Opitz, E. C. Vamvakas, E. C. Espiritu, S. A. Fineberg, and H. Feiner
Proliferation Kinetics of Non-Hodgkin's Lymphoma: Correlation With Histologic Grade According to the International Working Formulation
International Journal of Surgical Pathology, July 1, 1993; 1(1): 33 - 41.
[Abstract] [PDF]

Home page
 J. Biol. Chem.Home page
B. Razani, J. A. Engelman, X. B. Wang, W. Schubert, X. L. Zhang, C. B. Marks, F. Macaluso, R. G. Russell, M. Li, R. G. Pestell, et al.
Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities
J. Biol. Chem., October 5, 2001; 276(41): 38121 - 38138.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1991 by the American Society for Investigative Pathology.