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American Journal of Pathology, Vol 142, 351-352, Copyright © 1993 by American Society for Investigative Pathology

REGULAR ARTICLES

Registry of Experimental Cancers of the National Cancer Institute. A database resource for cancer research

JJ Berman, GW Moore, TP O'Neill, AG Liebelt and U Saffiotti
Department of Pathology, VA Medical Center, Baltimore, MD 21201.

The National Cancer Institute established the Registry of Experimental Cancers in March 1970. This registry consists of a permanent collection of pathological materials on spontaneous and induced lesions in laboratory animals that includes histological slides, paraffin blocks, autopsy findings, pathological diagnoses, photographs, and experimental records. The material presently is composed of approximately 60,000 consecutive records and is a valuable resource for researchers interested in tumors and other lesions arising spontaneously or from specific induction protocols in experimental animals. The entire registry database was transferred to an object-oriented database that permits registry staff to write programs for the different data field objects, thus customizing searches and other database functions. Twenty- seven animal species are represented and a total of 6,496 diagnostic entities and 1,106 treatment and control protocols are listed. Archival material may be retrieved for analysis of molecular markers.