help button home button Am J Pathol Epitomics
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS

This Article
Right arrow Order Full text via Infotrieve
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by DeLisser, H. M.
Right arrow Articles by Albelda, S. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by DeLisser, H. M.
Right arrow Articles by Albelda, S. M.

American Journal of Pathology, Vol 151, 671-677, Copyright © 1997 by American Society for Investigative Pathology

REGULAR ARTICLES

Involvement of endothelial PECAM-1/CD31 in angiogenesis

HM DeLisser, M Christofidou-Solomidou, RM Strieter, MD Burdick, CS Robinson, RS Wexler, JS Kerr, C Garlanda, JR Merwin, JA Madri and SM Albelda
Department of Medicine, University of Pennsylvania Medical Center, Philadelphia 19104-4283, USA. delisser@mail.med.upenn.edu

The adhesive interactions of endothelial cells with each other and the adhesion receptors that mediate these interactions are probably of fundamental importance to the process of angiogenesis. We therefore studied the effect of inhibiting the function of the endothelial cell- cell adhesion molecule, PECAM-1/ CD31, in rat and murine models of angiogenesis. A polyclonal antibody to human PECAM-1, which cross- reacts with rat PECAM-1, was found to block in vitro tube formation by rat capillary endothelial cells and cytokine-induced rat corneal neovascularization. In mice, two monoclonal antibodies against murine PECAM-1 prevented vessel growth into subcutaneously implanted gels supplemented with basic fibroblast growth factor (bFGF). Taken together these findings provide evidence that PECAM-1 is involved in angiogenesis and suggest that the interactions of endothelial cell-cell adhesion molecules are important in the formation of new vessels.


This article has been cited by other articles:


Home page
 Am. J. Pathol.Home page
G. Cao, M. L. Fehrenbach, J. T. Williams, J. M. Finklestein, J.-X. Zhu, and H. M. DeLisser
Angiogenesis in Platelet Endothelial Cell Adhesion Molecule-1-Null Mice
Am. J. Pathol., August 1, 2009; 175(2): 903 - 915.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
A. M. Randi and B. Bussolati
Myeloid cell-induced angiogenesis: a sticky business
Blood, June 25, 2009; 113(26): 6508 - 6510.
[Full Text] [PDF]

Home page
 J. Immunol.Home page
Y. Wu, K. Tworkoski, M. Michaud, and J. A. Madri
Bone Marrow Monocyte PECAM-1 Deficiency Elicits Increased Osteoclastogenesis Resulting in Trabecular Bone Loss
J. Immunol., March 1, 2009; 182(5): 2672 - 2679.
[Abstract] [Full Text] [PDF]

Home page
 JNMHome page
M. Yamato, Y. Kataoka, H. Mizuma, Y. Wada, and Y. Watanabe
PET and Macro- and Microautoradiographic Studies Combined with Immunohistochemistry for Monitoring Rat Intestinal Ulceration and Healing Processes
J. Nucl. Med., February 1, 2009; 50(2): 266 - 273.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
C. Bergom, C. Paddock, C. Gao, T. Holyst, D. K. Newman, and P. J. Newman
An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling
J. Cell Sci., April 15, 2008; 121(8): 1235 - 1242.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
R. Soleimani, J. Van der Elst, E. Heytens, R. Van den Broecke, J. Gerris, M. Dhont, C. Cuvelier, and P. De Sutter
Back muscle as a promising site for ovarian tissue transplantation, an animal model
Hum. Reprod., March 1, 2008; 23(3): 619 - 626.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
C.-m. Liang, C.-p. Zhong, R.-x. Sun, B.-b. Liu, C. Huang, J. Qin, S. Zhou, J. Shan, Y.-k. Liu, and S.-l. Ye
Local Expression of Secondary Lymphoid Tissue Chemokine Delivered by Adeno-Associated Virus within the Tumor Bed Stimulates Strong Anti-Liver Tumor Immunity
J. Virol., September 1, 2007; 81(17): 9502 - 9511.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
Y. Wu, T. Welte, M. Michaud, and J. A. Madri
PECAM-1: a multifaceted regulator of megakaryocytopoiesis
Blood, August 1, 2007; 110(3): 851 - 859.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
E. Groyer, A. Nicoletti, H. Ait-Oufella, J. Khallou-Laschet, A. Varthaman, A.-T. Gaston, O. Thaunat, S. V. Kaveri, R. Blatny, H. Stockinger, et al.
Atheroprotective Effect of CD31 Receptor Globulin Through Enrichment of Circulating Regulatory T-Cells
J. Am. Coll. Cardiol., July 24, 2007; 50(4): 344 - 350.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
J. H. Chidlow Jr., D. Shukla, M. B. Grisham, and C. G. Kevil
Pathogenic angiogenesis in IBD and experimental colitis: new ideas and therapeutic avenues
Am J Physiol Gastrointest Liver Physiol, July 1, 2007; 293(1): G5 - G18.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
S. Kondo, E. A. Scheef, N. Sheibani, and C. M. Sorenson
PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis
Am J Physiol Cell Physiol, June 1, 2007; 292(6): C2070 - C2083.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
T. S. Dhanjal, C. Pendaries, E. A. Ross, M. K. Larson, M. B. Protty, C. D. Buckley, and S. P. Watson
A novel role for PECAM-1 in megakaryocytokinesis and recovery of platelet counts in thrombocytopenic mice
Blood, May 15, 2007; 109(10): 4237 - 4244.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
J. H. Chidlow Jr., W. Langston, J. J.M. Greer, D. Ostanin, M. Abdelbaqi, J. Houghton, A. Senthilkumar, D. Shukla, A. P. Mazar, M. B. Grisham, et al.
Differential Angiogenic Regulation of Experimental Colitis
Am. J. Pathol., December 1, 2006; 169(6): 2014 - 2030.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
M. P. Pusztaszeri, W. Seelentag, and F. T. Bosman
Immunohistochemical Expression of Endothelial Markers CD31, CD34, von Willebrand Factor, and Fli-1 in Normal Human Tissues
J. Histochem. Cytochem., April 1, 2006; 54(4): 385 - 395.
[Abstract] [Full Text] [PDF]

Home page
 ReproductionHome page
F. Wynne, M. Ball, A. S McLellan, P. Dockery, W. Zimmermann, and T. Moore
Mouse pregnancy-specific glycoproteins: tissue-specific expression and evidence of association with maternal vasculature.
Reproduction, April 1, 2006; 131(4): 721 - 732.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H. M. DeLisser, B. P. Helmke, G. Cao, P. M. Egan, D. Taichman, M. Fehrenbach, A. Zaman, Z. Cui, G. S. Mohan, H. S. Baldwin, et al.
Loss of PECAM-1 Function Impairs Alveolarization
J. Biol. Chem., March 31, 2006; 281(13): 8724 - 8731.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
N. Wagner, K.-D. Wagner, H. Theres, C. Englert, A. Schedl, and H. Scholz
Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1
Genes & Dev., November 1, 2005; 19(21): 2631 - 2642.
[Abstract] [Full Text] [PDF]

Home page
 Circ. Res.Home page
M. Rajesh, A. Kolmakova, and S. Chatterjee
Novel Role of Lactosylceramide in Vascular Endothelial Growth Factor-Mediated Angiogenesis in Human Endothelial Cells
Circ. Res., October 14, 2005; 97(8): 796 - 804.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
P. L. W. Yun, A. A. Decarlo, C. C. Chapple, and N. Hunter
Functional Implication of the Hydrolysis of Platelet Endothelial Cell Adhesion Molecule 1 (CD31) by Gingipains of Porphyromonas gingivalis for the Pathology of Periodontal Disease
Infect. Immun., March 1, 2005; 73(3): 1386 - 1398.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. Tzima, J. S. Reader, M. Irani-Tehrani, K. L. Ewalt, M. A. Schwartz, and P. Schimmel
VE-cadherin Links tRNA Synthetase Cytokine to Anti-angiogenic Function
J. Biol. Chem., January 28, 2005; 280(4): 2405 - 2408.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
C. D. O'Brien, G. Cao, A. Makrigiannakis, and H. M. DeLisser
Role of immunoreceptor tyrosine-based inhibitory motifs of PECAM-1 in PECAM-1-dependent cell migration
Am J Physiol Cell Physiol, October 1, 2004; 287(4): C1103 - C1113.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
S. M. Albelda, K. C. Lau, P. Chien, Z.-Y. Huang, E. Arguiris, A. Bohen, J. Sun, J. A. Billet, M. Christofidou-Solomidou, Z. K. Indik, et al.
Role for Platelet-Endothelial Cell Adhesion Molecule-1 in Macrophage Fc{gamma} Receptor Function
Am. J. Respir. Cell Mol. Biol., August 1, 2004; 31(2): 246 - 255.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
G. Bazzoni and E. Dejana
Endothelial Cell-to-Cell Junctions: Molecular Organization and Role in Vascular Homeostasis
Physiol Rev, July 1, 2004; 84(3): 869 - 901.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
T. Furusawa, K. Ohkoshi, C. Honda, S. Takahashi, and T. Tokunaga
Embryonic Stem Cells Expressing Both Platelet Endothelial Cell Adhesion Molecule-1 and Stage-Specific Embryonic Antigen-1 Differentiate Predominantly into Epiblast Cells in a Chimeric Embryo
Biol Reprod, May 1, 2004; 70(5): 1452 - 1457.
[Abstract] [Full Text] [PDF]

Home page
 Molecular Cancer TherapeuticsHome page
S. Swenson, F. Costa, R. Minea, R. P. Sherwin, W. Ernst, G. Fujii, D. Yang, and F. S. Markland Jr.
Intravenous liposomal delivery of the snake venom disintegrin contortrostatin limits breast cancer progression
Mol. Cancer Ther., April 1, 2004; 3(4): 499 - 511.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
D. R. Gray, W. J. Huss, J. M. Yau, L. E. Durham, E. S. Werdin, W. K. Funkhouser Jr., and G. J. Smith
Short-Term Human Prostate Primary Xenografts: An in Vivo Model of Human Prostate Cancer Vasculature and Angiogenesis
Cancer Res., March 1, 2004; 64(5): 1712 - 1721.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
T. Semba, Y. Funahashi, N. Ono, Y. Yamamoto, N. H. Sugi, M. Asada, K. Yoshimatsu, and T. Wakabayashi
An Angiogenesis Inhibitor E7820 Shows Broad-Spectrum Tumor Growth Inhibition in a Xenograft Model: Possible Value of Integrin {alpha}2 on Platelets as a Biological Marker
Clin. Cancer Res., February 15, 2004; 10(4): 1430 - 1438.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
D. Feng, J. A. Nagy, K. Pyne, H. F. Dvorak, and A. M. Dvorak
Ultrastructural Localization of Platelet Endothelial Cell Adhesion Molecule (PECAM-1, CD31) in Vascular Endothelium
J. Histochem. Cytochem., January 1, 2004; 52(1): 87 - 102.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. Ishida, R. K. Kundu, E. Yang, K.-i. Hirata, Y.-D. Ho, and T. Quertermous
Targeted Disruption of Endothelial Cell-selective Adhesion Molecule Inhibits Angiogenic Processes in Vitro and in Vivo
J. Biol. Chem., September 5, 2003; 278(36): 34598 - 34604.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
D. GRATZINGER, S. CANOSA, B. ENGELHARDT, and J. A. MADRI
Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho
FASEB J, August 1, 2003; 17(11): 1458 - 1469.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
A. Solowiej, P. Biswas, D. Graesser, and J. A. Madri
Lack of Platelet Endothelial Cell Adhesion Molecule-1 Attenuates Foreign Body Inflammation because of Decreased Angiogenesis
Am. J. Pathol., March 1, 2003; 162(3): 953 - 962.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
J. M. Enciso, D. Gratzinger, T. D. Camenisch, S. Canosa, E. Pinter, and J. A. Madri
Elevated glucose inhibits VEGF-A-mediated endocardial cushion formation: modulation by PECAM-1 and MMP-2
J. Cell Biol., February 18, 2003; 160(4): 605 - 615.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
S. Tasaka, L. Qin, A. Saijo, S. M. Albelda, H. M. DeLisser, and C. M. Doerschuk
Platelet Endothelial Cell Adhesion Molecule-1 in Neutrophil Emigration during Acute Bacterial Pneumonia in Mice and Rats
Am. J. Respir. Crit. Care Med., January 15, 2003; 167(2): 164 - 170.
[Abstract] [Full Text] [PDF]

Home page
 Mol Cancer ResHome page
J. Tapon-Bretaudiere, D. Chabut, M. Zierer, S. Matou, D. Helley, A. Bros, P. A.S. Mourao, and A.-M. Fischer
A Fucosylated Chondroitin Sulfate From Echinoderm Modulates in Vitro Fibroblast Growth Factor 2-Dependent Angiogenesis
Mol. Cancer Res., December 1, 2002; 1(2): 96 - 102.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
Y. Funahashi, N. H. Sugi, T. Semba, Y. Yamamoto, S. Hamaoka, N. Tsukahara-Tamai, Y. Ozawa, A. Tsuruoka, K. Nara, K. Takahashi, et al.
Sulfonamide Derivative, E7820, Is a Unique Angiogenesis Inhibitor Suppressing an Expression of Integrin {alpha}2 Subunit on Endothelium
Cancer Res., November 1, 2002; 62(21): 6116 - 6123.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
T. Akimoto, H. Liapis, and M. R. Hammerman
Microvessel formation from mouse embryonic aortic explants is oxygen and VEGF dependent
Am J Physiol Regulatory Integrative Comp Physiol, August 1, 2002; 283(2): R487 - R495.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M.-X. Wong, D. Roberts, P. A. Bartley, and D. E. Jackson
Absence of Platelet Endothelial Cell Adhesion Molecule-1 (CD31) Leads to Increased Severity of Local and Systemic IgE-Mediated Anaphylaxis and Modulation of Mast Cell Activation
J. Immunol., June 15, 2002; 168(12): 6455 - 6462.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
G. Ren, L. H. Michael, M. L. Entman, and N. G. Frangogiannis
Morphological Characteristics of the Microvasculature in Healing Myocardial Infarcts
J. Histochem. Cytochem., January 1, 2002; 50(1): 71 - 80.
[Abstract] [Full Text]

Home page
 Exp Biol MedHome page
A. RayChaudhury, M. Elkins, D. Kozien, and M. T. Nakada
Regulation of PECAM-1 in Endothelial Cells during Cell Growth and Migration
Exp Biol Med, July 1, 2001; 226(7): 686 - 691.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
A. K. Sood, E. A. Seftor, M. S. Fletcher, L. M. G. Gardner, P. M. Heidger, R. E. Buller, R. E. B. Seftor, and M. J. C. Hendrix
Molecular Determinants of Ovarian Cancer Plasticity
Am. J. Pathol., April 1, 2001; 158(4): 1279 - 1288.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
E. Prager, G. Staffler, O. Majdic, M. D. Saemann, S. Godar, G. J. Zlabinger, and H. Stockinger
Induction of Hyporesponsiveness and Impaired T Lymphocyte Activation by the CD31 Receptor:Ligand Pathway in T Cells
J. Immunol., February 15, 2001; 166(4): 2364 - 2371.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
T. Zhao and P. J. Newman
Integrin Activation by Regulated Dimerization and Oligomerization of Platelet Endothelial Cell Adhesion Molecule (Pecam)-1 from within the Cell
J. Cell Biol., January 8, 2001; 152(1): 65 - 74.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
G. Zeng, L. Gao, S. Birkle, and R. K. Yu
Suppression of Ganglioside GD3 Expression in a Rat F-11 Tumor Cell Line Reduces Tumor Growth, Angiogenesis, and Vascular Endothelial Growth Factor Production
Cancer Res., December 1, 2000; 60(23): 6670 - 6676.
[Abstract] [Full Text]

Home page
 Am. J. Pathol.Home page
A. Li, S. Sakaguchi, K. Shigematsu, R. Atarashi, B. C. Roy, R. Nakaoke, K. Arima, N. Okimura, J. Kopacek, and S. Katamine
Physiological Expression of the Gene for PrP-Like Protein, PrPLP/Dpl, by Brain Endothelial Cells and its Ectopic Expression in Neurons of PrP-Deficient Mice Ataxic Due to Purkinje Cell Degeneration
Am. J. Pathol., November 1, 2000; 157(5): 1447 - 1452.
[Abstract] [Full Text] [PDF]

Home page
 J. Histochem. Cytochem.Home page
A. Marszalek, T. Daa, K. Kashima, I. Nakayama, and S. Yokoyama
Ultrastructural and Morphometric Studies Related to Expression of the Cell Adhesion Molecule PECAM-1/CD31 in Developing Rat Lung
J. Histochem. Cytochem., September 1, 2000; 48(9): 1283 - 1290.
[Abstract] [Full Text]

Home page
 Mol. Biol. CellHome page
C. W.Y. Wong, G. Wiedle, C. Ballestrem, B. Wehrle-Haller, S. Etteldorf, M. Bruckner, B. Engelhardt, R. H. Gisler, and B. A. Imhof
PECAM-1/CD31 Trans-homophilic Binding at the Intercellular Junctions Is Independent of Its Cytoplasmic Domain; Evidence for Heterophilic Interaction with Integrin alpha vbeta 3 in Cis
Mol. Biol. Cell, September 1, 2000; 11(9): 3109 - 3121.
[Abstract] [Full Text]

Home page
 Mol. Biol. CellHome page
N. Sheibani, C. M. Sorenson, and W. A. Frazier
Differential Modulation of Cadherin-mediated Cell-Cell Adhesion by Platelet Endothelial Cell Adhesion Molecule-1 Isoforms through Activation of Extracellular Regulated Kinases
Mol. Biol. Cell, August 1, 2000; 11(8): 2793 - 2802.
[Abstract] [Full Text]

Home page
 Am. J. Pathol.Home page
S. Mahooti, D. Graesser, S. Patil, P. Newman, G. Duncan, T. Mak, and J. A. Madri
PECAM-1 (CD31) Expression Modulates Bleeding Time in Vivo
Am. J. Pathol., July 1, 2000; 157(1): 75 - 81.
[Abstract] [Full Text] [PDF]

Home page
 Pharmacol. Rev.Home page
A. W. Griffioen and G. Molema
Angiogenesis: Potentials for Pharmacologic Intervention in the Treatment of Cancer, Cardiovascular Diseases, and Chronic Inflammation
Pharmacol. Rev., June 1, 2000; 52(2): 237 - 268.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
V. L. Bautch, S. D. Redick, A. Scalia, M. Harmaty, P. Carmeliet, and R. Rapoport
Characterization of the vasculogenic block in the absence of vascular endothelial growth factor-A
Blood, March 15, 2000; 95(6): 1979 - 1987.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
C. J. Drake and P. A. Fleming
Vasculogenesis in the day 6.5 to 9.5 mouse embryo
Blood, March 1, 2000; 95(5): 1671 - 1679.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
C.E. Gargett, K. Bucak, and P.A.W. Rogers
Isolation, characterization and long-term culture of human myometrial microvascular endothelial cells
Hum. Reprod., February 1, 2000; 15(2): 293 - 301.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
J Sun, C Paddock, J Shubert, H. Zhang, K Amin, P. Newman, and S. Albelda
Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization
J. Cell Sci., January 4, 2000; 113(8): 1459 - 1469.
[Abstract] [PDF]

Home page
 J. Cell Sci.Home page
C Johnson-Leger, M Aurrand-Lions, and B. Imhof
The parting of the endothelium: miracle, or simply a junctional affair?
J. Cell Sci., January 3, 2000; 113(6): 921 - 933.
[Abstract] [PDF]

Home page
 Am. J. Pathol.Home page
S. Yang, J. Graham, J. W. Kahn, E. A. Schwartz, and M. E. Gerritsen
Functional Roles for PECAM-1 (CD31) and VE-Cadherin (CD144) in Tube Assembly and Lumen Formation in Three-Dimensional Collagen Gels
Am. J. Pathol., September 1, 1999; 155(3): 887 - 895.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
B. Vailhe, J. Dietl, M. Kapp, B. Toth, and P. Arck
Increased blood vessel density in decidua parietalis is associated with spontaneous human first trimester abortion
Hum. Reprod., June 1, 1999; 14(6): 1628 - 1634.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
S. D. Redick and V. L. Bautch
Developmental Platelet Endothelial Cell Adhesion Molecule Expression Suggests Multiple Roles for a Vascular Adhesion Molecule
Am. J. Pathol., April 1, 1999; 154(4): 1137 - 1147.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
G. S. Duncan, D. P. Andrew, H. Takimoto, S. A. Kaufman, H. Yoshida, J. Spellberg, J. Luis de la Pompa, A. Elia, A. Wakeham, B. Karan-Tamir, et al.
Genetic Evidence for Functional Redundancy of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1): CD31-Deficient Mice Reveal PECAM-1-Dependent and PECAM-1-Independent Functions
J. Immunol., March 1, 1999; 162(5): 3022 - 3030.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
N Ilan, S Mahooti, D. Rimm, and J. Madri
PECAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated beta-catenin
J. Cell Sci., January 9, 1999; 112(18): 3005 - 3014.
[Abstract] [PDF]

Home page
 J. Cell Sci.Home page
P. Hordijk, E Anthony, F. Mul, R Rientsma, L. Oomen, and D Roos
Vascular-endothelial-cadherin modulates endothelial monolayer permeability
J. Cell Sci., January 6, 1999; 112(12): 1915 - 1923.
[Abstract] [PDF]

Home page
 J. Biol. Chem.Home page
T. L. Bach, C. Barsigian, C. H. Yaen, and J. Martinez
Endothelial Cell VE-cadherin Functions as a Receptor for the beta 15-42 Sequence of Fibrin
J. Biol. Chem., November 13, 1998; 273(46): 30719 - 30728.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Q.-H. Sun, C. Paddock, G. P. Visentin, M. M. Zukowski, W. A. Muller, and P. J. Newman
Cell Surface Glycosaminoglycans Do Not Serve as Ligands for PECAM-1. PECAM-1 IS NOT A HEPARIN-BINDING PROTEIN
J. Biol. Chem., May 8, 1998; 273(19): 11483 - 11490.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
N. Sheibani and W. A. Frazier
Down-Regulation of Platelet Endothelial Cell Adhesion Molecule-1 Results in Thrombospondin-1 Expression and Concerted Regulation of Endothelial Cell Phenotype
Mol. Biol. Cell, April 1, 1998; 9(4): 701 - 713.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
K.-i. Hirata, T. Ishida, K. Penta, M. Rezaee, E. Yang, J. Wohlgemuth, and T. Quertermous
Cloning of an Immunoglobulin Family Adhesion Molecule Selectively Expressed by Endothelial Cells
J. Biol. Chem., May 4, 2001; 276(19): 16223 - 16231.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
G. Cao, C. D. O'Brien, Z. Zhou, S. M. Sanders, J. N. Greenbaum, A. Makrigiannakis, and H. M. DeLisser
Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migration
Am J Physiol Cell Physiol, May 1, 2002; 282(5): C1181 - C1190.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1997 by the American Society for Investigative Pathology.