| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Commentary |


From the Departments of Pathology*
and
Oncology,
The Johns Hopkins Medical
Institutions, Baltimore, Maryland
Abstract
This article has been cited by other articles:
![]() |
A. Vincent, M.-P. Ducourouble, and I. Van Seuningen Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases FASEB J, August 1, 2008; 22(8): 3035 - 3045. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Feldmann and A. Maitra Molecular Genetics of Pancreatic Ductal Adenocarcinomas and Recent Implications for Translational Efforts J. Mol. Diagn., March 1, 2008; 10(2): 111 - 122. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. M. Winter, A. H. Ting, F. Vilardell, E. Gallmeier, S. B. Baylin, R. H. Hruban, S. E. Kern, and C. A. Iacobuzio-Donahue Absence of E-Cadherin Expression Distinguishes Noncohesive from Cohesive Pancreatic Cancer Clin. Cancer Res., January 15, 2008; 14(2): 412 - 418. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. V. Gold, Z. Karanjawala, D. E. Modrak, D. M. Goldenberg, and R. H. Hruban PAM4-Reactive MUC1 Is a Biomarker for Early Pancreatic Adenocarcinoma Clin. Cancer Res., December 15, 2007; 13(24): 7380 - 7387. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. E Brand, M. M Lerch, W. S Rubinstein, J. P Neoptolemos, D. C Whitcomb, R. H Hruban, T. A Brentnall, H. T Lynch, M. I Canto, and Participants of the Fourth International Symposium Advances in counselling and surveillance of patients at risk for pancreatic cancer Gut, October 1, 2007; 56(10): 1460 - 1469. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. Kojima, S. M. Vickers, N. V. Adsay, N. C. Jhala, H.-G. Kim, T. R. Schoeb, W. E. Grizzle, and C. A. Klug Inactivation of Smad4 Accelerates KrasG12D-Mediated Pancreatic Neoplasia Cancer Res., September 1, 2007; 67(17): 8121 - 8130. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. A Khalifa Intraoperative assessment of the Whipple resection specimen J. Clin. Pathol., September 1, 2007; 60(9): 975 - 980. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Mahadevan and D. D. Von Hoff Tumor-stroma interactions in pancreatic ductal adenocarcinoma Mol. Cancer Ther., April 1, 2007; 6(4): 1186 - 1197. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Ueda, K. Fukamachi, Y. Matsuoka, N. Takasuka, F. Takeshita, A. Naito, M. Iigo, D. B. Alexander, M. A. Moore, I. Saito, et al. Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas Carcinogenesis, December 1, 2006; 27(12): 2497 - 2510. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. K. Rustgi The molecular pathogenesis of pancreatic cancer: clarifying a complex circuitry. Genes & Dev., November 15, 2006; 20(22): 3049 - 3053. [Full Text] [PDF] |
||||
![]() |
J Kim, H A Reber, S M Dry, D Elashoff, S L Chen, N Umetani, M Kitago, O J Hines, K K Kazanjian, S Hiramatsu, et al. Unfavourable prognosis associated with K-ras gene mutation in pancreatic cancer surgical margins Gut, November 1, 2006; 55(11): 1598 - 1605. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. M. Wiktor-Brown, C. A. Hendricks, W. Olipitz, and B. P. Engelward Age-dependent accumulation of recombinant cells in the mouse pancreas revealed by in situ fluorescence imaging PNAS, August 8, 2006; 103(32): 11862 - 11867. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. B. Deramaudt, M. Takaoka, R. Upadhyay, M. J. Bowser, J. Porter, A. Lee, B. Rhoades, C. N. Johnstone, R. Weissleder, S. R. Hingorani, et al. N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell Migration, Invasion, and Tissue Architecture Disruption. Mol. Cell. Biol., June 1, 2006; 26(11): 4185 - 4200. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Giovannetti, V. Mey, S. Nannizzi, G. Pasqualetti, M. Del Tacca, and R. Danesi Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer. Mol. Cancer Ther., June 1, 2006; 5(6): 1387 - 1395. [Abstract] [Full Text] [PDF] |
||||
![]() |
F Bergmann, S Aulmann, M N Wente, R Penzel, I Esposito, J Kleeff, H Friess, and P Schirmacher Molecular characterisation of pancreatic ductal adenocarcinoma in patients under 40 J. Clin. Pathol., June 1, 2006; 59(6): 580 - 584. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. F. Hezel, A. C. Kimmelman, B. Z. Stanger, N. Bardeesy, and R. A. DePinho Genetics and biology of pancreatic ductal adenocarcinoma. Genes & Dev., May 15, 2006; 20(10): 1218 - 1249. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Bardeesy, A. J. Aguirre, G. C. Chu, K.-h. Cheng, L. V. Lopez, A. F. Hezel, B. Feng, C. Brennan, R. Weissleder, U. Mahmood, et al. From the Cover: Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse PNAS, April 11, 2006; 103(15): 5947 - 5952. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. H. Hruban, N. V. Adsay, J. Albores-Saavedra, M. R. Anver, A. V. Biankin, G. P. Boivin, E. E. Furth, T. Furukawa, A. Klein, D. S. Klimstra, et al. Pathology of Genetically Engineered Mouse Models of Pancreatic Exocrine Cancer: Consensus Report and Recommendations Cancer Res., January 1, 2006; 66(1): 95 - 106. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Qian, J. Niu, M. Li, P. J. Chiao, and M.-S. Tsao In vitro Modeling of Human Pancreatic Duct Epithelial Cell Transformation Defines Gene Expression Changes Induced by K-ras Oncogenic Activation in Pancreatic Carcinogenesis Cancer Res., June 15, 2005; 65(12): 5045 - 5053. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. E. Dowen, T. Crnogorac-Jurcevic, R. Gangeswaran, M. Hansen, J. J. Eloranta, V. Bhakta, T. A. Brentnall, J. Luttges, G. Kloppel, and N. R. Lemoine Expression of S100P and Its Novel Binding Partner S100PBPR in Early Pancreatic Cancer Am. J. Pathol., January 1, 2005; 166(1): 81 - 92. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Aguilar, J. M. Corominas, N. Malats, J. A. Pereira, M. Dufresne, F. X. Real, and P. Navarro Tissue Plasminogen Activator in Murine Exocrine Pancreas Cancer: Selective Expression in Ductal Tumors and Contribution to Cancer Progression Am. J. Pathol., October 1, 2004; 165(4): 1129 - 1139. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. T. Henke, B. R. Haddad, S. E. Kim, J. D. Rone, A. Mani, J. M. Jessup, A. Wellstein, A. Maitra, and A. T. Riegel Overexpression of the Nuclear Receptor Coactivator AIB1 (SRC-3) during Progression of Pancreatic Adenocarcinoma Clin. Cancer Res., September 15, 2004; 10(18): 6134 - 6142. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Takahashi, T. Oda, T. Hasebe, Y. Aoyagi, T. Kinoshita, M. Konishi, T. Nakagohri, K. Inoue, S. Takahashi, H. Kawahira, et al. Biologically Different Subgroups of Invasive Ductal Carcinoma of the Pancreas: Dpc4 Status According to the Ratio of Intraductal Carcinoma Components Clin. Cancer Res., June 1, 2004; 10(11): 3772 - 3779. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. E. Jones, M. J. Humphreys, F. Campbell, J. P. Neoptolemos, and M. T. Boyd Comprehensive Analysis of Matrix Metalloproteinase and Tissue Inhibitor Expression in Pancreatic Cancer: Increased Expression of Matrix Metalloproteinase-7 Predicts Poor Survival Clin. Cancer Res., April 15, 2004; 10(8): 2832 - 2845. [Abstract] [Full Text] [PDF] |
||||
![]() |
J.-K. Lin, S.-C. Chang, Y.-C. Yang, and A. F.-Y. Li Loss of Heterozygosity and DNA Aneuploidy in Colorectal Adenocarcinoma Ann. Surg. Oncol., November 1, 2003; 10(9): 1086 - 1094. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. J. Grippo, P. S. Nowlin, M. J. Demeure, D. S. Longnecker, and E. P. Sandgren Preinvasive Pancreatic Neoplasia of Ductal Phenotype Induced by Acinar Cell Targeting of Mutant Kras in Transgenic Mice Cancer Res., May 1, 2003; 63(9): 2016 - 2019. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Matsubayashi, N. Sato, N. Fukushima, C. J. Yeo, K. M. Walter, K. Brune, F. Sahin, R. H. Hruban, and M. Goggins Methylation of Cyclin D2 Is Observed Frequently in Pancreatic Cancer but Is Also an Age-related Phenomenon in Gastrointestinal Tissues Clin. Cancer Res., April 1, 2003; 9(4): 1446 - 1452. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. A. French, E. K. Alexander, E. S. Cibas, V. Nose, J. Laguette, W. Faquin, J. Garber, F. Moore Jr, J. A. Fletcher, P. R. Larsen, et al. Genetic and Biological Subgroups of Low-Stage Follicular Thyroid Cancer Am. J. Pathol., April 1, 2003; 162(4): 1053 - 1060. [Abstract] [Full Text] [PDF] |
||||
![]() |
N Howes and J P Neoptolemos Risk of pancreatic ductal adenocarcinoma in chronic pancreatitis Gut, December 1, 2002; 51(6): 765 - 766. [Full Text] [PDF] |
||||
![]() |
N. T. van Heek, A. K. Meeker, S. E. Kern, C. J. Yeo, K. D. Lillemoe, J. L. Cameron, G. J. A. Offerhaus, J. L. Hicks, R. E. Wilentz, M. G. Goggins, et al. Telomere Shortening Is Nearly Universal in Pancreatic Intraepithelial Neoplasia Am. J. Pathol., November 1, 2002; 161(5): 1541 - 1547. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Hennig, X.-Z. Ding, W.-G. Tong, M. B. Schneider, J. Standop, H. Friess, M. W. Buchler, P. M. Pour, and T. E. Adrian 5-Lipoxygenase and Leukotriene B4 Receptor Are Expressed in Human Pancreatic Cancers But Not in Pancreatic Ducts in Normal Tissue Am. J. Pathol., August 1, 2002; 161(2): 421 - 428. [Abstract] [Full Text] [PDF] |
||||
![]() |
A V Biankin, S A Biankin, J G Kench, A L Morey, C-S Lee, D R Head, R P Eckstein, T B Hugh, S M Henshall, and R L Sutherland Aberrant p16INK4A and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma Gut, June 1, 2002; 50(6): 861 - 868. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Fukushima, N. Sato, T. Ueki, C. Rosty, K. M. Walter, R. E. Wilentz, C. J. Yeo, R. H. Hruban, and M. Goggins Aberrant Methylation of Preproenkephalin and p16 Genes in Pancreatic Intraepithelial Neoplasia and Pancreatic Ductal Adenocarcinoma Am. J. Pathol., May 1, 2002; 160(5): 1573 - 1581. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. Ryu, J. Jones, N. J. Blades, G. Parmigiani, M. A. Hollingsworth, R. H. Hruban, and S. E. Kern Relationships and Differentially Expressed Genes among Pancreatic Cancers Examined by Large-scale Serial Analysis of Gene Expression Cancer Res., February 1, 2002; 62(3): 819 - 826. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. V. Biankin, J. G. Kench, A. L. Morey, C.-S. Lee, S. A. Biankin, D. R. Head, T. B. Hugh, S. M. Henshall, and R. L. Sutherland Overexpression of p21WAF1/CIP1 is an Early Event in the Development of Pancreatic Intraepithelial Neoplasia Cancer Res., December 1, 2001; 61(24): 8830 - 8837. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Luttges, H. Galehdari, V. Brocker, I. Schwarte-Waldhoff, D. Henne-Bruns, G. Kloppel, W. Schmiegel, and S. A. Hahn Allelic Loss Is Often the First Hit in the Biallelic Inactivation of the p53 and DPC4 Genes During Pancreatic Carcinogenesis Am. J. Pathol., May 1, 2001; 158(5): 1677 - 1683. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. M. Henshall, D. I. Quinn, C. S. Lee, D. R. Head, D. Golovsky, P. C. Brenner, W. Delprado, P. D. Stricker, J. J. Grygiel, and R. L. Sutherland Overexpression of the Cell Cycle Inhibitor p16INK4A in High-grade Prostatic Intraepithelial Neoplasia Predicts Early Relapse in Prostate Cancer Patients Clin. Cancer Res., March 1, 2001; 7(3): 544 - 550. [Abstract] [Full Text] |
||||
![]() |
R. H. Hruban, M. Goggins, J. Parsons, and S. E. Kern Progression Model for Pancreatic Cancer Clin. Cancer Res., August 1, 2000; 6(8): 2969 - 2972. [Full Text] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |