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(American Journal of Pathology. 2009;174:1594-1596.)
© 2009 American Society for Investigative Pathology
DOI: 10.2353/ajpath.2009.090198

Commentary

Angiogenic Monocytes

Another Colorful Blow to Endothelial Progenitors

Anton J.G. Horrevoets

From the Department of Molecular Cell Biology and Immunology, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands

Abstract

This Commentary provides perspective on a related article by Sun-Jin Kim and coworkers (Am J Pathol: 172 AJP08-0819), who assess the contribution of bone marrow-derived cells to tumor angiogenesis in a physiologic, non-myeloablative setting and conclude that the actual angiogenic cell type incorporated in the newly formed vessels is actually monocytes/macrophages.




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