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American Journal of Pathology, Vol 85, 73-84, Copyright © 1976 by American Society for Investigative Pathology

REGULAR ARTICLES

Histopathology of spontaneous regression in virus-induced murine leukemia

I Russo, J Russo, J Baldwin and MA Rich

The histopathology of the spontaneous regression of murine leukemia induced by a particular strain of Friend leukemia virus was studied in Swiss ICR/Ha mice. Animals inoculated with the regressing strain of Friend virus exhibited an initial pathologic response identical to that induced by conventional strains of Friend virus. Unlike the fatal leukemia produced by conventional Friend virus, the pathology of the disease induced by the regressing strain of Friend virus appeared to be self-limiting. The histopathology of the two diseases is compared in this report.




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Copyright © 1976 by the American Society for Investigative Pathology.