help button home button Am J Pathol Angiogenesis Meeting
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS

This Article
Right arrow Order Full text via Infotrieve
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Myrie, C.
Right arrow Articles by Ramsey, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Myrie, C.
Right arrow Articles by Ramsey, D.

American Journal of Pathology, Vol 99, 243-252, Copyright © 1980 by American Society for Investigative Pathology

REGULAR ARTICLES

Light-microscopic analysis of sectioned Sezary cells: an accurate alternative to electron microscopy

C Myrie, D Zucker-Franklin and D Ramsey

The prognostic implications of circulating Sezary cells in mycosis fungoides (MF) are not known, and the significance of fluctuating Sezary cell counts in either MF or the Sezary syndrome has not been assessed. Such studies have been hampered by the inaccuracy of counts performed on routine blood smears and the unavailability of electron microscopy for routine purposes. The present studies conducted on the peripheral blood of 35 patients with either MF or the Sezary syndrome show that Sezary cell counts performed by light microscopy of sectioned Epon-embedded lymphocyte fractions are as accurate as those carried out at the ultrastructural level. In addition, the studies include preliminary observations concerning 20 patients whose Sezary cell counts were repeated over time intervals ranging from 3 months to over 5 years. The described method should facilitate the performance of blood and lymph node Sezary cell counts on a wider scale, which is a necessity if the significance of circulating Sezary cells is to be evaluated.


This article has been cited by other articles:


Home page
 PediatricsHome page
D. Zucker-Franklin, M. K. Kosann, B. A. Pancake, D. L. Ramsay, and N. A. Soter
Hypopigmented Mycosis Fungoides Associated With Human T Cell Lymphotropic Virus Type I Tax in a Pediatric Patient
Pediatrics, May 1, 1999; 103(5): 1039 - 1044.
[Full Text]

Home page
 CVIHome page
B.-N. Lee, M. Duvic, C.-K. Tang, C. Bueso-Ramos, Z. Estrov, and J. M. Reuben
Dysregulated Synthesis of Intracellular Type 1 and Type 2 Cytokines by T Cells of Patients with Cutaneous T-Cell Lymphoma
Clin. Vaccine Immunol., January 1, 1999; 6(1): 79 - 84.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1980 by the American Society for Investigative Pathology.