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A more recent version of this article appeared on August 1, 2007

Published online before print June 28, 2007
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Copyright © 2007 American Society for Investigative Pathology
American Journal of Pathology, doi:10.2353/ajpath.2007.070342

Accepted for publication May 23, 2007.

Article

A Perspective on DNA Microarrays in Pathology Research and Practice

Jonathan R. Pollack@

From the Department of Pathology, Stanford University, Stanford, California

@ To whom correspondence should be addressed. E-mail: pollack1{at}stanford.edu.


  Abstract

DNA microarray technology matured in the mid-1990s, and the past decade has witnessed a tremendous growth in its application. DNA microarrays have provided powerful tools for pathology researchers seeking to describe, classify, and understand human disease. There has also been great expectation that the technology would advance the practice of pathology. This review highlights some of the key contributions of DNA microarrays to experimental pathology, focusing in the area of cancer research. Also discussed are some of the current challenges in translating utility to clinical practice.






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Copyright © 2007 by the American Society for Investigative Pathology.