
Figure 2. IHC for CD138/Syndecan 1
(left) shows
strong staining by PCs in all biopsies (Poly.
PCs, polyclonal plasmacytosis; LPL/WM, lymphoplasmacytoid
lymphoma/Waldenstroms macroglobulinemia; MM no LL, multiple myeloma
without lytic lesions; and MM with LL, multiple myeloma with lytic
lesions). IHC for CD56/NCAM
(right) shows
strong expression in the linear rows of paratrabecular osteoblasts used
as internal positive controls
(arrows, spindle-shaped cells
adjacent to a bony trabeculum in each frame).
The PCs are CD56/NCAM-negative in all biopsies except MM with LL
(open
arrow).