Reversible Demyelination, Blood-Brain Barrier Breakdown, and Pronounced Neutrophil Recruitment Induced by Chronic IL-1 Expression in the Brain
Am J Pathol Ferrari et al.
165: 1827
Supplement for Am J Pathol 2004, 165:1827-1837
Supplementary Figures 1 and 2 for Am J Pathol 2004, 165:1827-1837
Files in this Data Supplement:
Supplemental Figures -
Supplemental Figures 1 and 2 (PDF document; 158 KB)
Supplemental Figure 1: Cresyl violet staining of representative sections of cortex including the meninges. No
inflammation is observed in the meninges surrounding the injection site 2 (A) or 14 days (B) after AdIL-1â administration. Inset: Higher magnification of the meninges after
2 days of injection. Scale bar: A- B, 100µm; inset, 50µm.
Supplemental Figure 2: Degenerative axon characterized by flocular dense material, swelling mitochondria
and vesicles probably filled with neurofilaments. Scale bar: 500nm
