Warner-Lambert/Parke-Davis Award Lecture:

Michael R. Lieber

Pathological and Physiological Double-Strand Breaks : Roles in Cancer, Aging, and the Immune System
Am J Pathol 1998 153: 1323-1332. [Abstract] [Full Text]  

Commentaries:

Juha Laurén, Yuji Gunji, and Kari Alitalo

Is Angiopoietin-2 Necessary for the Initiation of Tumor Angiogenesis?
Am J Pathol 1998 153: 1333-1339. [Full Text]  

Hans Konrad Müller-Hermelink and Axel Greiner

Molecular Analysis of Human Immunoglobulin Heavy Chain Variable Genes (IgVH) in Normal and Malignant B Cells
Am J Pathol 1998 153: 1341-1346. [Full Text]  

Richard E. B. Seftor

Role of the ß₃ Integrin Subunit in Human Primary Melanoma Progression : Multifunctional Activities Associated with_vß₃ Integrin Expression
Am J Pathol 1998 153: 1347-1351. [Full Text]  

Short Communications:

Johannes Pammer, Wolfgang Weninger, and Erwin Tschachler

Human Keratinocytes Express Cellular Prion-Related Protein in Vitro and during Inflammatory Skin Diseases
Am J Pathol 1998 153: 1353-1358. [Abstract] [Full Text]  

M.G. Spillantini, R.A. Crowther, W. Kamphorst, P. Heutink, and J.C. van Swieten

Tau Pathology in Two Dutch Families with Mutations in the Microtubule-Binding Region of Tau
Am J Pathol 1998 153: 1359-1363. [Abstract] [Full Text]  

Carol F. Lippa, Hideo Fujiwara, David M.A. Mann, Benoit Giasson, Minami Baba, Marie L. Schmidt, Linda E. Nee, Brendan O'Connell, Dan A. Pollen, Peter St. George-Hyslop, Bernardino Ghetti, David Nochlin, Thomas D. Bird, Nigel J. Cairns, Virginia M.-Y. Lee, Takeshi Iwatsubo, and John Q. Trojanowski

Lewy Bodies Contain Altered -Synuclein in Brains of Many Familial Alzheimer's Disease Patients with Mutations in Presenilin and Amyloid Precursor Protein Genes
Am J Pathol 1998 153: 1365-1370. [Abstract] [Full Text]  

Jörg Koglin, Troels Glysing-Jensen, John S. Mudgett, and Mary E. Russell

NOS2 Mediates Opposing Effects in Models of Acute and Chronic Cardiac Rejection : Insights from NOS2-Knockout Mice
Am J Pathol 1998 153: 1371-1376. [Abstract] [Full Text]  

Fabio Benigni, Silvano Sacco, Luigi Aloe, and Pietro Ghezzi

Intracerebroventricular Injection of Anti-Fas Activates the Hypothalamus-Pituitary-Adrenal Axis and Induces Peripheral Interleukin-6 and Serum Amyloid A in Mice : Comparison with Other Ligands of the Tumor Necrosis Factor/NerveGrowth Factor Receptor Superfamily
Am J Pathol 1998 153: 1377-1381. [Abstract] [Full Text]  

Technical Advances:

Jennifer L. Stinn, Marta K. Taylor, Gerold Becker, Hiroaki Nagano, Satoru Hasegawa, Yutaka Furakawa, Koichi Shimizu, Peter Libby, and Richard N. Mitchell

Interferon--Secreting T-Cell Populations in Rejecting Murine Cardiac Allografts : Assessment by Flow Cytometry
Am J Pathol 1998 153: 1383-1392. [Abstract] [Full Text]  

Satoshi Shiokawa, Junji Nishimura, Kouichi Ohshima, Naokuni Uike, and Kazuhiko Yamamoto

Establishment of a Novel B Cell Clonality Analysis Using Single-Strand Conformation Polymorphism of Immunoglobulin Light Chain Messenger Signals
Am J Pathol 1998 153: 1393-1400. [Abstract] [Full Text]  

Jon M. Davison, Thomas W. Morgan, Bae-Li Hsi, Sheng Xiao, and Jonathan A. Fletcher

Subtracted, Unique-Sequence, In Situ Hybridization : Experimental and Diagnostic Applications
Am J Pathol 1998 153: 1401-1409. [Abstract] [Full Text]  

Regular Articles:

James W. Mandell, Isa M. Hussaini, Maja Zecevic, Michael J. Weber, and Scott R. VandenBerg

In Situ Visualization of Intratumor Growth Factor Signaling : Immunohistochemical Localization of Activated ERK/MAP Kinase in Glial Neoplasms
Am J Pathol 1998 153: 1411-1423. [Abstract] [Full Text]  

Christian Zietz, Matthias Rössle, Christian Haas, Andrea Sendelhofert, Astrid Hirschmann, Michael Stürzl, and Udo Löhrs

MDM-2 Oncoprotein Overexpression, p53 Gene Mutation, and VEGF Up-Regulation in Angiosarcomas
Am J Pathol 1998 153: 1425-1433. [Abstract] [Full Text]  

Mei-Yu Hsu, Daw-Tsun Shih, Friedegund E. Meier, Patricia Van Belle, Ju-Yu Hsu, David E. Elder, Clayton A. Buck, and Meenhard Herlyn

Adenoviral Gene Transfer of ß3 Integrin Subunit Induces Conversion from Radial to Vertical Growth Phase in Primary Human Melanoma
Am J Pathol 1998 153: 1435-1442. [Abstract] [Full Text]  

Andrew H. Fischer, Jane A. Bond, Panya Taysavang, O. Eugene Battles, and David Wynford-Thomas

Papillary Thyroid Carcinoma Oncogene (RET/PTC) Alters the Nuclear Envelope and Chromatin Structure
Am J Pathol 1998 153: 1443-1450. [Abstract] [Full Text]  

Brian P. Rubin, Chang-Jie Chen, Thomas W. Morgan, Sheng Xiao, Holcombe E. Grier, Harry P. Kozakewich, Antonio R. Perez-Atayde, and Jonathan A. Fletcher

Congenital Mesoblastic Nephroma t(12;15) Is Associated with ETV6-NTRK3 Gene Fusion : Cytogenetic and Molecular Relationship to Congenital (Infantile)Fibrosarcoma
Am J Pathol 1998 153: 1451-1458. [Abstract] [Full Text]  

Astrid Stratmann, Werner Risau, and Karl H. Plate

Cell Type-Specific Expression of Angiopoietin-1 and Angiopoietin-2 Suggests a Role in Glioblastoma Angiogenesis
Am J Pathol 1998 153: 1459-1466. [Abstract] [Full Text]  

Feng Jiang, Jan Richter, Peter Schraml, Lukas Bubendorf, Thomas Gasser, Guido Sauter, Michael Jörg Mihatsch, and Holger Moch

Chromosomal Imbalances in Papillary Renal Cell Carcinoma : Genetic Differences between Histological Subtypes
Am J Pathol 1998 153: 1467-1473. [Abstract] [Full Text]  

Xiang Qian, Long Jin, Elzbieta Kulig, and Ricardo V. Lloyd

DNA Methylation Regulates p27^Kip1 Expression in Rodent Pituitary Cell Lines
Am J Pathol 1998 153: 1475-1482. [Abstract] [Full Text]  

Andreas Chott, Wolfgang Haedicke, Isabella Mosberger, Manuela Födinger, Karin Winkler, Christine Mannhalter, and Hans-Konrad Müller-Hermelink

Most CD56⁺ Intestinal Lymphomas Are CD8⁺CD5^- T-Cell Lymphomas of Monomorphic Small to Medium Size Histology
Am J Pathol 1998 153: 1483-1490. [Abstract] [Full Text]  

Anne Räisänen-Sokolowski, Troels Glysing-Jensen, and Mary E. Russell

Leukocyte-Suppressing Influences of Interleukin (IL)-10 in Cardiac Allografts : Insights from IL-10 Knockout Mice
Am J Pathol 1998 153: 1491-1500. [Abstract] [Full Text]  

Eloisa Arbustini, Marta Diegoli, Roberta Fasani, Maurizia Grasso, Patrizia Morbini, Nadia Banchieri, Ornella Bellini, Barbara Dal Bello, Andrea Pilotto, Giulia Magrini, Carlo Campana, Paolo Fortina, Antonello Gavazzi, Jagat Narula, and Mario Viganò

Mitochondrial DNA Mutations and Mitochondrial Abnormalities in Dilated Cardiomyopathy
Am J Pathol 1998 153: 1501-1510. [Abstract] [Full Text]  

Michio Nagata, Kei-ichi Nakayama, Yoshio Terada, Sachi Hoshi, and Teruo Watanabe

Cell Cycle Regulation and Differentiation in the Human Podocyte Lineage
Am J Pathol 1998 153: 1511-1520. [Abstract] [Full Text]  

Béatrice Nawrocki, Myriam Polette, Jolanda Van Hengel, Jean-Marie Tournier, Frans Van Roy, and Philippe Birembaut

Cytoplasmic Redistribution of E-Cadherin-Catenin Adhesion Complex Is Associated with Down-Regulated Tyrosine Phosphorylation of E-Cadherin in Human Bronchopulmonary Carcinomas
Am J Pathol 1998 153: 1521-1530. [Abstract] [Full Text]  

Junru Wang, Huaien Zheng, Ching-Ching Sung, Konrad K. Richter, and Martin Hauer-Jensen

Cellular Sources of Transforming Growth Factor-ß Isoforms in Early and Chronic Radiation Enteropathy
Am J Pathol 1998 153: 1531-1540. [Abstract] [Full Text]  

Megan S. Lim, Stephen E. Straus, Janet K. Dale, Thomas A. Fleisher, Maryalice Stetler-Stevenson, Warren Strober, Michael C. Sneller, Jennifer M. Puck, Michael J. Lenardo, Kojo S. J. Elenitoba-Johnson, Albert Y. Lin, Mark Raffeld, and Elaine S. Jaffe

Pathological Findings in Human Autoimmune Lymphoproliferative Syndrome
Am J Pathol 1998 153: 1541-1550. [Abstract] [Full Text]  

Ayae Kinoshita, Makoto Kinoshita, Haruhiko Akiyama, Hidekazu Tomimoto, Ichiro Akiguchi, Sharad Kumar, Makoto Noda, and Jun Kimura

Identification of Septins in Neurofibrillary Tangles in Alzheimer's Disease
Am J Pathol 1998 153: 1551-1560. [Abstract] [Full Text]  

Adolfo Jiménez-Huete, Patricia M. J. Lievens, Rubén Vidal, Pedro Piccardo, Bernardino Ghetti, Fabrizio Tagliavini, Blas Frangione, and Frances Prelli

Endogenous Proteolytic Cleavage of Normal and Disease-Associated Isoforms of the Human Prion Protein in Neural and Non-Neural Tissues
Am J Pathol 1998 153: 1561-1572. [Abstract] [Full Text]  

Darren Paul Stevenson, William Patrick Collins, Farzin Farzaneh, Kohkichi Hata, and Kohji Miyazaki

Thymidine Phosphorylase Activity and Prodrug Effects in a Three-Dimensional Model of Angiogenesis : Implications for the Treatment of Ovarian Cancer
Am J Pathol 1998 153: 1573-1578. [Abstract] [Full Text]  

Pascal Roger, Pascal Pujol, Annick Lucas, Pierre Baldet, and Henri Rochefort

Increased Immunostaining of Fibulin-1, an Estrogen-Regulated Protein in the Stroma of Human Ovarian Epithelial Tumors
Am J Pathol 1998 153: 1579-1588. [Abstract] [Full Text]  

Giuseppe Montrucchio, Anna Sapino, Benedetta Bussolati, Gianpiero Ghisolfi, Simona Rizea-Savu, Luigi Silvestro, Enrico Lupia, and Giovanni Camussi

Potential Angiogenic Role of Platelet-Activating Factor in Human Breast Cancer
Am J Pathol 1998 153: 1589-1596. [Abstract] [Full Text]  

Eric Adriaenssens, Lionel Dumont, Séverine Lottin, Domitille Bolle, Alain Leprêtre, Alice Delobelle, Fatima Bouali, Thierry Dugimont, Jean Coll, and Jean-Jacques Curgy

H19 Overexpression in Breast Adenocarcinoma Stromal Cells Is Associated with Tumor Values and Steroid Receptor Status but Independent of p53 and Ki-67 Expression
Am J Pathol 1998 153: 1597-1607. [Abstract] [Full Text]  

András Matolcsy, Roland G. Nádor, Ethel Cesarman, and Daniel M. Knowles

Immunoglobulin V_H Gene Mutational Analysis Suggests that Primary Effusion Lymphomas Derive from Different Stages of B Cell Maturation
Am J Pathol 1998 153: 1609-1614. [Abstract] [Full Text]  

Jan Richter, Lorenza Beffa, Urs Wagner, Peter Schraml, Thomas C. Gasser, Holger Moch, Michael J. Mihatsch, and Guido Sauter

Patterns of Chromosomal Imbalances in Advanced Urinary Bladder Cancer Detected by Comparative Genomic Hybridization
Am J Pathol 1998 153: 1615-1621. [Abstract] [Full Text]  

Animal Models:

Volker Straub, Franck Duclos, David P. Venzke, Jane C. Lee, Susan Cutshall, Cynthia J. Leveille, and Kevin P. Campbell

Molecular Pathogenesis of Muscle Degeneration in the -Sarcoglycan-Deficient Hamster
Am J Pathol 1998 153: 1623-1630. [Abstract] [Full Text]  

John M. Galasso, Jeffrey K. Harrison, and Faye S. Silverstein

Excitotoxic Brain Injury Stimulates Expression of the Chemokine Receptor CCR5 in Neonatal Rats
Am J Pathol 1998 153: 1631-1640. [Abstract] [Full Text]  

Takao Tobe, Sagrario Ortega, Jose D. Luna, Hiroaki Ozaki, Naoyuki Okamoto, Nancy L. Derevjanik, Stanley A. Vinores, Claudio Basilico, and Peter A. Campochiaro

Targeted Disruption of the FGF2 Gene Does Not Prevent Choroidal Neovascularization in a Murine Model
Am J Pathol 1998 153: 1641-1646. [Abstract] [Full Text]  

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