Commentaries:

Michel Goedert and Masato Hasegawa

The Tauopathies : Toward an Experimental Animal Model
Am J Pathol 1999 154: 1-6. [Full Text]  

Timothy C. Greiner

Advances in Molecular Hematopathology : T-Cell Receptor and bcl-2 Genes
Am J Pathol 1999 154: 7-9. [Full Text]  

Mary T. Walsh

A Novel Amyloidogenic Variant of Apolipoprotein AI : Implications for a Conformational Change Leading to Cardiomyopathy
Am J Pathol 1999 154: 11-14. [Full Text]  

Short Communications:

Margaret Heung-Ling Ng, Amanda Kan, Yuk-Fei Chung, Ivy Hing-Nam Wong, Kwok-Wai Lo, Nicolas William Rupert Wickham, Kenny Ieng-Kit Lei, and Joseph Chuen-Kwan Lee

Combined Morphological and Interphase Fluorescence in Situ Hybridization Study in Multiple Myeloma of Chinese Patients
Am J Pathol 1999 154: 15-22. [Abstract] [Full Text]  

Shinji Sakurai, Tomoki Fukasawa, Ja-Mun Chong, Akira Tanaka, and Masashi Fukayama

Embryonic Form of Smooth Muscle Myosin Heavy Chain (SMemb/MHC-B) in Gastrointestinal Stromal Tumor and Interstitial Cells of Cajal
Am J Pathol 1999 154: 23-28. [Abstract] [Full Text]  

Nick Barker, Gerwin Huls, Vladimir Korinek, and Hans Clevers

Restricted High Level Expression of Tcf-4 Protein in Intestinal and Mammary Gland Epithelium
Am J Pathol 1999 154: 29-35. [Abstract] [Full Text]  

Nathalie Wong, Paul Lai, Siu-Wah Lee, Susanna Fan, Elizabeth Pang, Choong-Tsek Liew, Zhong Sheng, Joseph Wan-Yee Lau, and Philip James Johnson

Assessment of Genetic Changes in Hepatocellular Carcinoma by Comparative Genomic Hybridization Analysis : Relationship to Disease Stage, Tumor Size, and Cirrhosis
Am J Pathol 1999 154: 37-43. [Abstract] [Full Text]  

Patrick Van Der Voorn, Janneke Tekstra, Rob H.J. Beelen, Cornelis P. Tensen, Paul Van Der Valk, and Corline J.A. De Groot

Expression of MCP-1 by Reactive Astrocytes in Demyelinating Multiple Sclerosis Lesions
Am J Pathol 1999 154: 45-51. [Abstract] [Full Text]  

Jerzy Lasota, Marek Jasinski, Maarit Sarlomo-Rikala, and Markku Miettinen

Mutations in Exon 11 of c-Kit Occur Preferentially in Malignant versus Benign Gastrointestinal Stromal Tumors and Do Not Occur in Leiomyomas or Leiomyosarcomas
Am J Pathol 1999 154: 53-60. [Abstract] [Full Text]  

Technical Advances:

Falko Fend, Michael R. Emmert-Buck, Rodrigo Chuaqui, Kristina Cole, Jeff Lee, Lance A. Liotta, and Mark Raffeld

Immuno-LCM: Laser Capture Microdissection of Immunostained Frozen Sections for mRNA Analysis
Am J Pathol 1999 154: 61-66. [Abstract] [Full Text]  

Sabina Signoretti, Michael Murphy, Maria Giulia Cangi, Pietro Puddu, Marshall E. Kadin, and Massimo Loda

Detection of Clonal T-Cell Receptor Gene Rearrangements in Paraffin-Embedded Tissue by Polymerase Chain Reaction and Nonradioactive Single-Strand Conformational Polymorphism Analysis
Am J Pathol 1999 154: 67-75. [Abstract] [Full Text]  

Gary G. McIntosh, Andrew J. Lodge, Peter Watson, Andrew G. Hall, Katrina Wood, John J. Anderson, Brian Angus, Charles H. W. Horne, and Ian D. Milton

NCL-CD10–270: A New Monoclonal Antibody Recognizing CD10 in Paraffin-Embedded Tissue
Am J Pathol 1999 154: 77-82. [Abstract] [Full Text]  

Wolfgang Dietmaier, Arndt Hartmann, Sabine Wallinger, Ernst Heinmöller, Thomas Kerner, Elmar Endl, Karl-Walter Jauch, Ferdinand Hofstädter, and Josef Rüschoff

Multiple Mutation Analyses in Single Tumor Cells with Improved Whole Genome Amplification
Am J Pathol 1999 154: 83-95. [Abstract] [Full Text]  

Sandra D. Bohling, Thomas C. King, Carl T. Wittwer, and Kojo S. J. Elenitoba-Johnson

Rapid Simultaneous Amplification and Detection of the MBR/JH Chromosomal Translocation by Fluorescence Melting Curve Analysis
Am J Pathol 1999 154: 97-103. [Abstract] [Full Text]  

Liju Yang, Cindy X. Qiu, Anna Ludlow, Mark W. J. Ferguson, and Georg Brunner

Active Transforming Growth Factor-ß in Wound Repair : Determination Using a New Assay
Am J Pathol 1999 154: 105-111. [Abstract] [Full Text]  

Regular Articles:

Han-Xiang An, Matthias W. Beckmann, Guido Reifenberger, Hans G. Bender, and Dieter Niederacher

Gene Amplification and Overexpression of CDK4 in Sporadic Breast Carcinomas Is Associated with High Tumor Cell Proliferation
Am J Pathol 1999 154: 113-118. [Abstract] [Full Text]  

Elizabeth W. Newcomb, Meg Sosnow, Rita I. Demopoulos, Anne Zeleniuch-Jacquotte, Joan Sorich, and James L. Speyer

Expression of the Cell Cycle Inhibitor p27^KIP1 Is a New Prognostic Marker Associated with Survival in Epithelial Ovarian Tumors
Am J Pathol 1999 154: 119-125. [Abstract] [Full Text]  

Claudio Soravia, Sonia L. Sugg, Terri Berk, Angela Mitri, Hong Cheng, Steven Gallinger, Zane Cohen, Sylvia L. Asa, and Bharati V. Bapat

Familial Adenomatous Polyposis-Associated Thyroid Cancer : A Clinical, Pathological, and Molecular Genetics Study
Am J Pathol 1999 154: 127-135. [Abstract] [Full Text]  

Philip Cornford, Jim Evans, Andrew Dodson, Keith Parsons, Alan Woolfenden, John Neoptolemos, and Christopher S. Foster

Protein Kinase C Isoenzyme Patterns Characteristically Modulated in Early Prostate Cancer
Am J Pathol 1999 154: 137-144. [Abstract] [Full Text]  

Fabio Facchetti, William Vermi, Simona Fiorentini, Marco Chilosi, Arnaldo Caruso, Marzia Duse, Luigi Daniele Notarangelo, and Raffaele Badolato

Expression of Inducible Nitric Oxide Synthase in Human Granulomas and Histiocytic Reactions
Am J Pathol 1999 154: 145-152. [Abstract] [Full Text]  

Thomas Knittel, Christina Dinter, Dominik Kobold, Katrin Neubauer, Mirko Mehde, Sören Eichhorst, and Giuliano Ramadori

Expression and Regulation of Cell Adhesion Molecules by Hepatic Stellate Cells (HSC) of Rat Liver : Involvment of HSC in Recruitment of Inflammatory Cells during Hepatic Tissue Repair
Am J Pathol 1999 154: 153-167. [Abstract] [Full Text]  

Jürgen Floege, Tammo Ostendorf, Ulf Janssen, Michael Burg, Heinfried H. Radeke, Chandra Vargeese, Stanley C. Gill, Louis S. Green, and Nebojsa Janjic

Novel Approach to Specific Growth Factor Inhibition in Vivo : Antagonism of Platelet-Derived Growth Factor inGlomerulonephritis by Aptamers
Am J Pathol 1999 154: 169-179. [Abstract] [Full Text]  

Youxin Yang, Cécile Jeanpierre, Gregory R. Dressler, Mireille Lacoste, Patrick Niaudet, and Marie-Claire Gubler

WT1 and PAX-2 Podocyte Expression in Denys-Drash Syndrome and Isolated Diffuse Mesangial Sclerosis
Am J Pathol 1999 154: 181-192. [Abstract] [Full Text]  

Jörn Sträter, Sara M. Mariani, Henning Walczak, Frank G. Rücker, Frank Leithäuser, Peter H. Krammer, and Peter Möller

CD95 Ligand (CD95L) in Normal Human Lymphoid Tissues : A Subset of Plasma Cells Are Prominent Producers of CD95L
Am J Pathol 1999 154: 193-201. [Abstract] [Full Text]  

Kurt D. Merkel, Jeanne M. Erdmann, Kevin P. McHugh, Yousef Abu-Amer, F. Patrick Ross, and Steven L. Teitelbaum

Tumor Necrosis Factor- Mediates Orthopedic Implant Osteolysis
Am J Pathol 1999 154: 203-210. [Abstract] [Full Text]  

Hans Hölschermann, Rainer M. Bohle, Hagen Zeller, Heiko Schmidt, Ulrich Stahl, Ludger Fink, Helmut Grimm, Harald Tillmanns, and Werner Haberbosch

In Situ Detection of Tissue Factor within the Coronary Intima in Rat Cardiac Allograft Vasculopathy
Am J Pathol 1999 154: 211-220. [Abstract] [Full Text]  

Ladan Hamidi Asl, Juris J. Liepnieks, Kamran Hamidi Asl, Tomoyuki Uemichi, Georges Moulin, Emmanuel Desjoyaux, Robert Loire, Marc Delpech, Gilles Grateau, and Merrill D. Benson

Hereditary Amyloid Cardiomyopathy Caused by a Variant Apolipoprotein A1
Am J Pathol 1999 154: 221-227. [Abstract] [Full Text]  

François Mach, Uwe Schönbeck, Rosalind P. Fabunmi, Curran Murphy, Elizabeth Atkinson, Jean-Yves Bonnefoy, Pierre Graber, and Peter Libby

T Lymphocytes Induce Endothelial Cell Matrix Metalloproteinase Expression by a CD40L-Dependent Mechanism : Implications for Tubule Formation
Am J Pathol 1999 154: 229-238. [Abstract] [Full Text]  

Alex B. Lentsch, Jacqueline A. Jordan, Boris J. Czermak, Kathleen M. Diehl, Ellen M. Younkin, Vidya Sarma, and Peter A. Ward

Inhibition of NF-B Activation and Augmentation of IBß by Secretory Leukocyte Protease Inhibitor during Lung Inflammation
Am J Pathol 1999 154: 239-247. [Abstract] [Full Text]  

Seiji Niho, Tomoyuki Yokose, Kenji Suzuki, Tetsuro Kodama, Yutaka Nishiwaki, and Kiyoshi Mukai

Monoclonality of Atypical Adenomatous Hyperplasia of the Lung
Am J Pathol 1999 154: 249-254. [Abstract] [Full Text]  

Jean-Pierre Brion, Gunter Tremp, and Jean-Noël Octave

Transgenic Expression of the Shortest Human Tau Affects Its Compartmentalization and Its Phosphorylation as in the Pretangle Stage of Alzheimer's Disease
Am J Pathol 1999 154: 255-270. [Abstract] [Full Text]  

Miho Enya, Maho Morishima-Kawashima, Masahiro Yoshimura, Yasuhisa Shinkai, Kaoru Kusui, Karen Khan, Dora Games, Dale Schenk, Shiro Sugihara, Haruyasu Yamaguchi, and Yasuo Ihara

Appearance of Sodium Dodecyl Sulfate-Stable Amyloid ß-Protein (Aß) Dimer in the Cortex During Aging
Am J Pathol 1999 154: 271-279. [Abstract] [Full Text]  

Sabine A. Eming, Martin L. Yarmush, Gerald G. Krueger, and Jeffrey R. Morgan

Regulation of the Spatial Organization of Mesenchymal Connective Tissue : Effects of Cell-Associated versus Released Isoforms of Platelet-Derived Growth Factor
Am J Pathol 1999 154: 281-289. [Abstract] [Full Text]  

Marco Paolo Martegani, Fabrizio Del Prete, Alessandra Gasbarri, Pier Giorgio Natali, and Armando Bartolazzi

Structural Variability of CD44v Molecules and Reliability of Immunodetection of CD44 Isoforms Using mAbs Specific for CD44 Variant Exon Products
Am J Pathol 1999 154: 291-300. [Abstract] [Full Text]  

Animal Models:

Liancun Wu, Yu-Ping Xia, Sanford I. Roth, Elliott Gruskin, and Thomas A. Mustoe

Transforming Growth Factor-ß1 Fails to Stimulate Wound Healing and Impairs Its Signal Transduction in an Aged Ischemic Ulcer Model : Importance of Oxygen and Age
Am J Pathol 1999 154: 301-309. [Abstract] [Full Text]  

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