Commentaries:

Keith R. Loeb and Lawrence A. Loeb

Genetic Instability and the Mutator Phenotype : Studies in Ulcerative Colitis
Am J Pathol 1999 154: 1621-1626. [Full Text]  

Dennis W. Dickson

Microglia in Alzheimer's Disease and Transgenic Models : How Close the Fit?
Am J Pathol 1999 154: 1627-1631. [Full Text]  

Jeffrey H. Miner

Alport Syndrome with Diffuse Leiomyomatosis : When and When Not?
Am J Pathol 1999 154: 1633-1635. [Full Text]  

Short Communications:

Wade S. Samowitz, Martha L. Slattery, John D. Potter, and Mark F. Leppert

BAT-26 and BAT-40 Instability in Colorectal Adenomas and Carcinomas and Germline Polymorphisms
Am J Pathol 1999 154: 1637-1641. [Abstract] [Full Text]  

Qingsheng Tian, Henry F. Frierson Jr., Geoffrey W. Krystal, and Christopher A. Moskaluk

Activating c-kit Gene Mutations in Human Germ Cell Tumors
Am J Pathol 1999 154: 1643-1647. [Abstract] [Full Text]  

Nobutaka Matsumura, Tsuneo Yamazaki, and Yasuo Ihara

Stable Expression in Chinese Hamster Ovary Cells of Mutated Tau Genes Causing Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 (FTDP-17)
Am J Pathol 1999 154: 1649-1656. [Abstract] [Full Text]  

Karen Pulford, Brunangelo Falini, Jaqueline Cordell, Andreas Rosenwald, German Ott, Hans-Konrad Müller-Hermelink, Kenneth A. MacLennan, Laurence Lamant, Antonio Carbone, Elias Campo, and David Y. Mason

Biochemical Detection of Novel Anaplastic Lymphoma Kinase Proteins in Tissue Sections of Anaplastic Large Cell Lymphoma
Am J Pathol 1999 154: 1657-1663. [Abstract] [Full Text]  

Technical Advances:

Joseph Geradts, Robert Maynard, Michael J. Birrer, Denver Hendricks, Susan L. Abbondanzo, Kwun M. Fong, J. Carl Barrett, and Donald P. Lombardi

Frequent Loss of KAI1 Expression in Squamous and Lymphoid Neoplasms : An Immunohistochemical Study of Archival Tissues
Am J Pathol 1999 154: 1665-1671. [Abstract] [Full Text]  

Regular Articles:

Martina Stalder, Amie Phinney, Alphonse Probst, Bernd Sommer, Matthias Staufenbiel, and Mathias Jucker

Association of Microglia with Amyloid Plaques in Brains of APP23 Transgenic Mice
Am J Pathol 1999 154: 1673-1684. [Abstract] [Full Text]  

A. van den Berg, L. Visser, and S. Poppema

High Expression of the CC Chemokine TARC in Reed-Sternberg Cells : A Possible Explanation for the Characteristic T-Cell Infiltratein Hodgkin's Lymphoma
Am J Pathol 1999 154: 1685-1691. [Abstract] [Full Text]  

Eric Santoni-Rugiu, Michael R. Jensen, Valentina M. Factor, and Snorri S. Thorgeirsson

Acceleration of c-myc-Induced Hepatocarcinogenesis by Co-Expression of Transforming Growth Factor (TGF)- in Transgenic Mice Is Associated with TGF-ß1 Signaling Disruption
Am J Pathol 1999 154: 1693-1700. [Abstract] [Full Text]  

Cornelia Stumptner, Hans Heid, Andrea Fuchsbichler, Hubert Hauser, Hans-Jörg Mischinger, Kurt Zatloukal, and Helmut Denk

Analysis of Intracytoplasmic Hyaline Bodies in a Hepatocellular Carcinoma : Demonstration of p62 as Major Constituent
Am J Pathol 1999 154: 1701-1710. [Abstract] [Full Text]  

Ludger Leifeld, Christian Trautwein, Franz Ludwig Dumoulin, Michael Peter Manns, Tilman Sauerbruch, and Ulrich Spengler

Enhanced Expression of CD80 (B7-1), CD86 (B7-2), and CD40 and Their Ligands CD28 and CD154 in Fulminant Hepatic Failure
Am J Pathol 1999 154: 1711-1720. [Abstract] [Full Text]  

Albert C. M. Ong, Christopher J. Ward, Robin J. Butler, Simon Biddolph, Coleen Bowker, Roser Torra, York Pei, and Peter C. Harris

Coordinate Expression of the Autosomal Dominant Polycystic Kidney Disease Proteins, Polycystin-2 And Polycystin-1, in Normal and Cystic Tissue
Am J Pathol 1999 154: 1721-1729. [Abstract] [Full Text]  

Marielle E. Kroon, Pieter Koolwijk, Harry van Goor, Ulrich H. Weidle, Annemie Collen, Gabri van der Pluijm, and Victor W. M. van Hinsbergh

Role and Localization of Urokinase Receptor in the Formation of New Microvascular Structures in Fibrin Matrices
Am J Pathol 1999 154: 1731-1742. [Abstract] [Full Text]  

Man Seong Seo, Nohoon Kwak, Hiroaki Ozaki, Haruhiko Yamada, Naoyuki Okamoto, Eri Yamada, Doriano Fabbro, Francesco Hofmann, Jeanette M. Wood, and Peter A. Campochiaro

Dramatic Inhibition of Retinal and Choroidal Neovascularization by Oral Administration of a Kinase Inhibitor
Am J Pathol 1999 154: 1743-1753. [Abstract] [Full Text]  

Michiko Watari, Hidemichi Watari, Michael E. DiSanto, Samuel Chacko, Guo-Ping Shi, and Jerome F. Strauss III

Pro-Inflammatory Cytokines Induce Expression of Matrix-Metabolizing Enzymes in Human Cervical Smooth Muscle Cells
Am J Pathol 1999 154: 1755-1762. [Abstract] [Full Text]  

Gary W. Hoyle, Jian Li, Jeffrey B. Finkelstein, Todd Eisenberg, Jing-Yao Liu, Joseph A. Lasky, Grace Athas, Gilbert F. Morris, and Arnold R. Brody

Emphysematous Lesions, Inflammation, and Fibrosis in the Lungs of Transgenic Mice Overexpressing Platelet-Derived Growth Factor
Am J Pathol 1999 154: 1763-1775. [Abstract] [Full Text]  

Nina N. Nupponen, Kati Porkka, Laura Kakkola, Minna Tanner, Karin Persson, Åke Borg, Jorma Isola, and Tapio Visakorpi

Amplification and Overexpression of p40 Subunit of Eukaryotic Translation Initiation Factor 3 in Breast and Prostate Cancer
Am J Pathol 1999 154: 1777-1783. [Abstract] [Full Text]  

Min Sun Shin, Won Sang Park, Su Young Kim, Ho Sik Kim, Seok Jin Kang, Kye Yong Song, Jik Young Park, Seung Myung Dong, Jae Ho Pi, Ro Ra Oh, Jung Young Lee, Nam Jin Yoo, and Sug Hyung Lee

Alterations of Fas (Apo-1/CD95) Gene in Cutaneous Malignant Melanoma
Am J Pathol 1999 154: 1785-1791. [Abstract] [Full Text]  

Claudia Verhagen, William Faber, Paul Klatser, Anita Buffing, Ben Naafs, and Pranab Das

Immunohistological Analysis of In Situ Expression of Mycobacterial Antigens in Skin Lesions of Leprosy Patients Across the Histopathological Spectrum : Association of Mycobacterial Lipoarabinomannan (LAM) and Mycobacterium leprae Phenolic Glycolipid-I (PGL-I) with Leprosy Reactions
Am J Pathol 1999 154: 1793-1804. [Abstract] [Full Text]  

Riccardo Dolcetti, Alessandra Viel, Claudio Doglioni, Antonio Russo, Massimo Guidoboni, Eugenia Capozzi, Nicola Vecchiato, Ettore Macrì, Mara Fornasarig, and Mauro Boiocchi

High Prevalence of Activated Intraepithelial Cytotoxic T Lymphocytes and Increased Neoplastic Cell Apoptosis in Colorectal Carcinomas with Microsatellite Instability
Am J Pathol 1999 154: 1805-1813. [Abstract] [Full Text]  

Jen-Lan Tsao, Simon Tavaré, Reijo Salovaara, Jeremy R. Jass, Lauri A. Aaltonen, and Darryl Shibata

Colorectal Adenoma and Cancer Divergence : Evidence of Multilineage Progression
Am J Pathol 1999 154: 1815-1824. [Abstract] [Full Text]  

Robert F. Willenbucher, Daniela E. Aust, Cornell G. Chang, Suzanne J. Zelman, Linda D. Ferrell, Dan H. Moore II, and Frederic M. Waldman

Genomic Instability Is an Early Event during the Progression Pathway of Ulcerative-Colitis-Related Neoplasia
Am J Pathol 1999 154: 1825-1830. [Abstract] [Full Text]  

Matthew Bjerknes and Hazel Cheng

Colossal Crypts Bordering Colon Adenomas in Apc^Min Mice Express Full-Length Apc
Am J Pathol 1999 154: 1831-1834. [Abstract] [Full Text]  

Gloria H. Su, Ralph H. Hruban, Ravi K. Bansal, G. Steven Bova, David J. Tang, Manu C. Shekher, Anne Marie Westerman, Mark M. Entius, Michael Goggins, Charles J. Yeo, and Scott E. Kern

Germline and Somatic Mutations of the STK11/LKB1 Peutz-Jeghers Gene in Pancreatic and Biliary Cancers
Am J Pathol 1999 154: 1835-1840. [Abstract] [Full Text]  

Christopher D. M. Fletcher, Paola Dal Cin, Ivo de Wever, Nils Mandahl, Fredrik Mertens, Felix Mitelman, Juan Rosai, Anders Rydholm, Raf Sciot, Giovanni Tallini, Herman van den Berghe, Roberta Vanni, and Helena Willén

Correlation between Clinicopathological Features and Karyotype in Spindle Cell Sarcomas : A Report of 130 Cases from the CHAMP Study Group
Am J Pathol 1999 154: 1841-1847. [Abstract] [Full Text]  

Christine Szych, Annette Staebler, Denise C. Connolly, Rong Wu, Kathleen R. Cho, and Brigitte M. Ronnett

Molecular Genetic Evidence Supporting the Clonality and Appendiceal Origin of Pseudomyxoma Peritonei in Women
Am J Pathol 1999 154: 1849-1855. [Abstract] [Full Text]  

Falko Fend, Leticia Quintanilla-Martinez, Shimareet Kumar, Michael W. Beaty, Loryn Blum, Lynn Sorbara, Elaine S. Jaffe, and Mark Raffeld

Composite Low Grade B-Cell Lymphomas with Two Immunophenotypically Distinct Cell Populations Are True Biclonal Lymphomas : A Molecular Analysis Using Laser Capture Microdissection
Am J Pathol 1999 154: 1857-1866. [Abstract] [Full Text]  

Patricia Lagadec, Stéphane Raynal, Blandine Lieubeau, Nathalie Onier, Laurent Arnould, Valérie Saint-Giorgio, David A. Lawrence, and Jean-François Jeannin

Evidence for Control of Nitric Oxide Synthesis by Intracellular Transforming Growth Factor-ß1 in Tumor Cells : Implications for Tumor Development
Am J Pathol 1999 154: 1867-1876. [Abstract] [Full Text]  

Elena Rodríguez-Iñigo, Javier Bartolomé, Susana de Lucas, Felix Manzarbeitia, Margarita Pardo, Carlos Arocena, Jaime Gosálvez, Horacio Oliva, and Vicente Carreño

Histological Damage in Chronic Hepatitis C Is Not Related to the Extent of Infection in the Liver
Am J Pathol 1999 154: 1877-1881. [Abstract] [Full Text]  

Keqin Zheng, Scott Harvey, Yoshikazu Sado, Ichiro Naito, Yoshifumi Ninomiya, Robert Jacobs, and Paul S. Thorner

Absence of the 6(IV) Chain of Collagen Type IV in Alport Syndrome Is Related to a Failure at the Protein Assembly Level and Does Not Result in Diffuse Leiomyomatosis
Am J Pathol 1999 154: 1883-1891. [Abstract] [Full Text]  

Andrea Martinuzzi, Giuliana Schievano, Annachiara Nascimbeni, and Marina Fanin

McArdle's Disease : The Unsolved Mystery of the Reappearing Enzyme
Am J Pathol 1999 154: 1893-1897. [Abstract] [Full Text]  

Richard A. Zager

Calcitriol Directly Sensitizes Renal Tubular Cells to ATP-Depletion- and Iron-Mediated Attack
Am J Pathol 1999 154: 1899-1909. [Abstract] [Full Text]  

Carmen A. Yiamouyiannis, Craig M. Schramm, Lynn Puddington, Peter Stengel, Ebrahim Baradaran-Hosseini, Walter W. Wolyniec, Herbert E. Whiteley, and Roger S. Thrall

Shifts in Lung Lymphocyte Profiles Correlate with the Sequential Development of Acute Allergic and Chronic Tolerant Stages in a Murine Asthma Model
Am J Pathol 1999 154: 1911-1921. [Abstract] [Full Text]  

Animal Models:

Jörn E. Schmitz, Meredith A. Simon, Marcelo J. Kuroda, Michelle A. Lifton, Markus W. Ollert, Carl-Wilhelm Vogel, Paul Racz, Klara Tenner-Racz, Bernard J. Scallon, Margaret Dalesandro, John Ghrayeb, E. Peter Rieber, Vito G. Sasseville, and Keith A. Reimann

A Nonhuman Primate Model for the Selective Elimination of CD8+ Lymphocytes Using a Mouse-Human Chimeric Monoclonal Antibody
Am J Pathol 1999 154: 1923-1932. [Abstract] [Full Text]  

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