Review:

Sakari Knuutila, Yan Aalto, Kirsi Autio, Anna-Maria Björkqvist, Wa'el El-Rifai, Samuli Hemmer, Tarja Huhta, Eeva Kettunen, Sonja Kiuru-Kuhlefelt, Marcelo L. Larramendy, Tamara Lushnikova, Outi Monni, Heini Pere, Johanna Tapper, Maija Tarkkanen, Asta Varis, Veli-Matti Wasenius, Maija Wolf, and Ying Zhu

DNA Copy Number Losses in Human Neoplasms
Am J Pathol 1999 155: 683-694. [Abstract] [Full Text]  

Commentaries:

Mina J. Bissell

Tumor Plasticity Allows Vasculogenic Mimicry, a Novel Form of Angiogenic Switch : A Rose by Any Other Name?
Am J Pathol 1999 155: 675-679. [Full Text]  

Onsi W. Kamel

Unraveling the Mystery of the Lymphoid Follicle
Am J Pathol 1999 155: 681-682. [Full Text]  

Short Communications:

Laura Obici, Vittorio Bellotti, Palma Mangione, Monica Stoppini, Eloisa Arbustini, Laura Verga, Irene Zorzoli, Ernesto Anesi, Giuseppe Zanotti, Carlo Campana, Mario Viganò, and Giampaolo Merlini

The New Apolipoprotein A-I Variant Leu¹⁷⁴ Ser Causes Hereditary Cardiac Amyloidosis, and the Amyloid Fibrils Are Constituted by the 93-Residue N-Terminal Polypeptide
Am J Pathol 1999 155: 695-702. [Abstract] [Full Text]  

Jeanne Tran Van Nhieu, Claire Angélique Renard, Yu Wei, Daniel Cherqui, Elie Serge Zafrani, and Marie Annick Buendia

Nuclear Accumulation of Mutated ß-Catenin in Hepatocellular Carcinoma Is Associated with Increased Cell Proliferation
Am J Pathol 1999 155: 703-710. [Abstract] [Full Text]  

Kenji Hibi, William H. Westra, Michael Borges, Steve Goodman, David Sidransky, and Jin Jen

PGP9.5 As a Candidate Tumor Marker for Non-Small-Cell Lung Cancer
Am J Pathol 1999 155: 711-715. [Abstract] [Full Text]  

Masayuki Kikukawa, Naoto Aoki, Yoshimitu Sakamoto, and Mayumi Mori

Study of p53 in Elderly Patients with Myelodysplastic Syndromes by Immunohistochemistry and DNA Analysis
Am J Pathol 1999 155: 717-721. [Abstract] [Full Text]  

Special Report:

Peter H. Byers

Molecular Genetic Pathology : Coming of Age in the Molecular World
Am J Pathol 1999 155: 673-674. [Full Text]  

Technical Advances:

Jack L. Arbiser, Gerhard Raab, Richard M. Rohan, Subroto Paul, Karen Hirschi, Evelyn Flynn, E. Roydon Price, David E. Fisher, Cynthia Cohen, and Michael Klagsbrun

Isolation of Mouse Stromal Cells Associated with a Human Tumor Using Differential Diphtheria Toxin Sensitivity
Am J Pathol 1999 155: 723-729. [Abstract] [Full Text]  

Regular Articles:

Roy King, Katherine N. Weilbaecher, Gaël McGill, Edward Cooley, Martin Mihm, and David E. Fisher

Microphthalmia Transcription Factor : A Sensitive and Specific Melanocyte Marker for MelanomaDiagnosis
Am J Pathol 1999 155: 731-738. [Abstract] [Full Text]  

Andrew J. Maniotis, Robert Folberg, Angela Hess, Elisabeth A. Seftor, Lynn M.G. Gardner, Jacob Pe'er, Jeffrey M. Trent, Paul S. Meltzer, and Mary J. C. Hendrix

Vascular Channel Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry
Am J Pathol 1999 155: 739-752. [Abstract] [Full Text]  

Manfred Kunz, Anke Hartmann, Egbert Flory, Atiye Toksoy, Dirk Koczan, Hans-Jürgen Thiesen, Nafoumi Mukaida, Manfred Neumann, Ulf Rüdiger Rapp, Eva-Bettina Bröcker, and Reinhard Gillitzer

Anoxia-Induced Up-Regulation of Interleukin-8 in Human Malignant Melanoma : A Potential Mechanism for High Tumor Aggressiveness
Am J Pathol 1999 155: 753-763. [Abstract] [Full Text]  

Markus Kaiser, Brian Younge, Johannes Björnsson, Jörg J. Goronzy, and Cornelia M. Weyand

Formation of New Vasa Vasorum in Vasculitis : Production of Angiogenic Cytokines by Multinucleated GiantCells
Am J Pathol 1999 155: 765-774. [Abstract] [Full Text]  

Agustín Melián, Yong-Jian Geng, Galina K. Sukhova, Peter Libby, and Steven A. Porcelli

CD1 Expression in Human Atherosclerosis : A Potential Mechanism for T Cell Activation by Foam Cells
Am J Pathol 1999 155: 775-786. [Abstract] [Full Text]  

Nhan L. Tran, Raymond B. Nagle, Anne E. Cress, and Ronald L. Heimark

N-Cadherin Expression in Human Prostate Carcinoma Cell Lines : An Epithelial-Mesenchymal Transformation Mediating Adhesion withStromal Cells
Am J Pathol 1999 155: 787-798. [Abstract] [Full Text]  

Giovanni Santelli, Daniela Califano, Gennaro Chiappetta, Maria Teresa Vento, Paola Cannada Bartoli, Fulvio Zullo, Francesco Trapasso, Giuseppe Viglietto, and Alfredo Fusco

Thymosin ß-10 Gene Overexpression Is a General Event in Human Carcinogenesis
Am J Pathol 1999 155: 799-804. [Abstract] [Full Text]  

Takuya Tsunoda, Mitsunori Yamakawa, and Tsuneo Takahashi

Differential Expression of Ca²⁺-Binding Proteins on Follicular Dendritic Cells in Non-Neoplastic and Neoplastic Lymphoid Follicles
Am J Pathol 1999 155: 805-814. [Abstract] [Full Text]  

Haruhisa Maruyama, Jörg Kleeff, Stefan Wildi, Helmut Friess, Markus W. Büchler, Mark A. Israel, and Murray Korc

Id-1 and Id-2 Are Overexpressed in Pancreatic Cancer and in Dysplastic Lesions in Chronic Pancreatitis
Am J Pathol 1999 155: 815-822. [Abstract] [Full Text]  

Massimo Guidoboni, Claudio Doglioni, Licia Laurino, Mauro Boiocchi, and Riccardo Dolcetti

Activation of Infiltrating Cytotoxic T Lymphocytes and Lymphoma Cell Apoptotic Rates in Gastric MALT Lymphomas : Differences between High-Grade and Low-Grade Cases
Am J Pathol 1999 155: 823-829. [Abstract] [Full Text]  

Andrew Barber, Stephen Courtenay Robson, and Fiona Lyall

Hemoxygenase and Nitric Oxide Synthase Do Not Maintain Human Uterine Quiescence during Pregnancy
Am J Pathol 1999 155: 831-840. [Abstract] [Full Text]  

Teshome Yehualaeshet, Robert O'Connor, Julia Green-Johnson, Sabine Mai, Roy Silverstein/p, Joanne E. Murphy-Ullrich, and Nasreen Khalil

Activation of Rat Alveolar Macrophage-Derived Latent Transforming Growth Factor ß-1 by Plasmin Requires Interaction with Thrombospondin-1 and its Cell Surface Receptor, CD36
Am J Pathol 1999 155: 841-851. [Abstract] [Full Text]  

Lih-Fen Lue, Yu-Min Kuo, Alex E. Roher, Libuse Brachova, Yong Shen, Lucia Sue, Thomas Beach, Janice H. Kurth, Russel E. Rydel, and Joseph Rogers

Soluble Amyloid ß Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's Disease
Am J Pathol 1999 155: 853-862. [Abstract] [Full Text]  

Thomas J. Montine, William R. Markesbery, William Zackert, Stephanie C. Sanchez, L. Jackson Roberts II, and Jason D. Morrow

The Magnitude of Brain Lipid Peroxidation Correlates with the Extent of Degeneration but Not with Density of Neuritic Plaques or Neurofibrillary Tangles or with APOE Genotype in Alzheimer's Disease Patients
Am J Pathol 1999 155: 863-868. [Abstract] [Full Text]  

Federico Licastro, Iain L. Campbell, Carrie Kincaid, Isaac Veinbergs, Emily Van Uden, Edward Rockenstein, Margaret Mallory, John R. Gilbert, and Eliezer Masliah

A Role for apoE in Regulating the Levels of -1-Antichymotrypsin in the Aging Mouse Brain and in Alzheimer's Disease
Am J Pathol 1999 155: 869-875. [Abstract] [Full Text]  

Harunobu Murayama, Ryong-Woon Shin, Jun Higuchi, Satoshi Shibuya, Tamaki Muramoto, and Tetsuyuki Kitamoto

Interaction of Aluminum with PHF in Alzheimer's Disease Neurofibrillary Degeneration Evidenced by Desferrioxamine-Assisted Chelating Autoclave Method
Am J Pathol 1999 155: 877-885. [Abstract] [Full Text]  

Suya Yang, Jennifer Graham, Jeanne W. Kahn, Eric A. Schwartz, and Mary E. Gerritsen

Functional Roles for PECAM-1 (CD31) and VE-Cadherin (CD144) in Tube Assembly and Lumen Formation in Three-Dimensional Collagen Gels
Am J Pathol 1999 155: 887-895. [Abstract] [Full Text]  

Fernando S. Santiago, David G. Atkins, and Levon M. Khachigian

Vascular Smooth Muscle Cell Proliferation and Regrowth after Mechanical Injury in Vitro Are Egr-1/NGFI-A-Dependent
Am J Pathol 1999 155: 897-905. [Abstract] [Full Text]  

Heikki Ahola, Shi-Xuan Wang, Pauliina Luimula, Marja-Liisa Solin, Lawrence B. Holzman, and Harry Holthöfer

Cloning and Expression of the Rat Nephrin Homolog
Am J Pathol 1999 155: 907-913. [Abstract] [Full Text]  

Markus Müschen, Ulrich Warskulat, Andreas Perniok, Jos Even, Cordula Moers, Berrin Kismet, Nazan Temizkan, Dietmar Simon, Matthias Schneider, and Dieter Häussinger

Involvement of Soluble CD95 in Churg-Strauss Syndrome
Am J Pathol 1999 155: 915-925. [Abstract] [Full Text]  

Mary M. Zutter, Samuel A. Santoro, Justina E. Wu, Tetsuro Wakatsuki, S. Kent Dickeson, and Elliot L. Elson

Collagen Receptor Control of Epithelial Morphogenesis and Cell Cycle Progression
Am J Pathol 1999 155: 927-940. [Abstract] [Full Text]  

Peiguo G. Chu, Karen L. Chang, Wen-Gang Chen, Yuan-Yuan Chen, Darryl Shibata, Kazukiko Hayashi, Carlos Bacchi, Maura Bacchi, and Lawrence M. Weiss

Epstein-Barr Virus (EBV) Nuclear Antigen (EBNA)-4 Mutation in EBV-Associated Malignancies in Three Different Populations
Am J Pathol 1999 155: 941-947. [Abstract] [Full Text]  

Ian Y. R. Adamson and Julita Bakowska

Relationship of Keratinocyte Growth Factor and Hepatocyte Growth Factor Levels in Rat Lung Lavage Fluid to Epithelial Cell Regeneration after Bleomycin
Am J Pathol 1999 155: 949-954. [Abstract] [Full Text]  

Cheng-long Huang, Nobuoki Kohno, Haruhiko Inufusa, Ken Kodama, Toshihiko Taki, and Masayuki Miyake

Overexpression of bax Associated with Mutations in the Loop-Sheet-Helix Motif of p53
Am J Pathol 1999 155: 955-965. [Abstract] [Full Text]  

Jennifer A. Doll, Xiaopei Zhu, Jaime Furman, Zahid Kaleem, Carlos Torres, Peter A. Humphrey, and Helen Donis-Keller

Genetic Analysis of Prostatic Atypical Adenomatous Hyperplasia (Adenosis)
Am J Pathol 1999 155: 967-971. [Abstract] [Full Text]  

Narendra Vyavahare, Matthew Ogle, Frederick J. Schoen, and Robert J. Levy

Elastin Calcification and its Prevention with Aluminum Chloride Pretreatment
Am J Pathol 1999 155: 973-982. [Abstract] [Full Text]  

Animal Models:

Lieve Umans, Lutgarde Serneels, Lut Overbergh, Lou Stas, and Fred Van Leuven

2-Macroglobulin- and Murinoglobulin-1- Deficient Mice : A Mouse Model for Acute Pancreatitis
Am J Pathol 1999 155: 983-993. [Abstract] [Full Text]  

Kevin A. Kelley, Lap Ho, David Winger, Jose Freire-Moar, Cy Blanco Borelli, Paul S. Aisen, and Giulio Maria Pasinetti

Potentiation of Excitotoxicity in Transgenic Mice Overexpressing Neuronal Cyclooxygenase-2
Am J Pathol 1999 155: 995-1004. [Abstract] [Full Text]  

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