Rous-Whipple Award Lecture:

Errol C. Friedberg

Nucleotide Excision Repair and Cancer Predisposition : A Journey from Man to Yeast to Mice
Am J Pathol 2000 157: 693-701. [Full Text]  

Short Communications:

Victoria A. Ploplis, Julie Wilberding, Laura McLennan, Zhong Liang, Ivo Cornelissen, Melanie E. DeFord, Elliot D. Rosen, and Francis J. Castellino

A Total Fibrinogen Deficiency Is Compatible with the Development of Pulmonary Fibrosis in Mice
Am J Pathol 2000 157: 703-708. [Abstract] [Full Text]  

Frank M. Raaphorst, Folkert J. van Kemenade, Tjasso Blokzijl, Elly Fieret, Karien M. Hamer, David P. E. Satijn, Arie P. Otte, and Chris J. L. M. Meijer

Coexpression of BMI-1 and EZH2 Polycomb Group Genes in Reed-Sternberg Cells of Hodgkin’s Disease
Am J Pathol 2000 157: 709-715. [Abstract] [Full Text]  

Yasushi Endoh, Gen Tamura, Yoichi Ajioka, Hidenobu Watanabe, and Teiichi Motoyama

Frequent Hypermethylation of the hMLH1 Gene Promoter in Differentiated-Type Tumors of the Stomach with the Gastric Foveolar Phenotype
Am J Pathol 2000 157: 717-722. [Abstract] [Full Text]  

Technical Advances:

Kenta Oode, Tomoko Furuya, Kei Harada, Shigeto Kawauchi, Koutaro Yamamoto, Takashi Hirano, and Kohsuke Sasaki

The Development of a Cell Array and Its Combination with Laser-Scanning Cytometry Allows a High-Throughput Analysis of Nuclear DNA Content
Am J Pathol 2000 157: 723-728. [Abstract] [Full Text]  

Regular Articles:

Joseph J. Y. Sung, Wai K. Leung, Minnie Y. Y. Go, Ka F. To, Alfred S. L. Cheng, Enders K. W. Ng, and Francis K. L. Chan

Cyclooxygenase-2 Expression in Helicobacter pylori-Associated Premalignant and Malignant Gastric Lesions
Am J Pathol 2000 157: 729-735. [Abstract] [Full Text]  

S. Nicholas Agoff, Teresa A. Brentnall, David A. Crispin, Shari L. Taylor, Stuart Raaka, Rodger C. Haggitt, Michael W. Reed, Irina A. Afonina, Peter S. Rabinovitch, Allyn C. Stevens, Ziding Feng, and Mary P. Bronner

The Role of Cyclooxygenase 2 in Ulcerative Colitis-Associated Neoplasia
Am J Pathol 2000 157: 737-745. [Abstract] [Full Text]  

Susan C. Abraham, Bunsei Nobukawa, Francis M. Giardiello, Stanley R. Hamilton, and Tsung-Teh Wu

Fundic Gland Polyps in Familial Adenomatous Polyposis : Neoplasms with Frequent Somatic Adenomatous Polyposis Coli Gene Alterations
Am J Pathol 2000 157: 747-754. [Abstract] [Full Text]  

Christine A. Iacobuzio-Donahue, David S. Klimstra, N. Volkan Adsay, Robb E. Wilentz, Pedram Argani, Taylor A. Sohn, Charles J. Yeo, John L. Cameron, Scott E. Kern, and Ralph H. Hruban

Dpc-4 Protein Is Expressed in Virtually All Human Intraductal Papillary Mucinous Neoplasms of the Pancreas : Comparison with Conventional Ductal Adenocarcinomas
Am J Pathol 2000 157: 755-761. [Abstract] [Full Text]  

Hey-Chi Hsu, Yung-Ming Jeng, Tsui-Lien Mao, Jan-Show Chu, Po-Lin Lai, and Shian-Yang Peng

ß-Catenin Mutations Are Associated with a Subset of Low-Stage Hepatocellular Carcinoma Negative for Hepatitis B Virus and with Favorable Prognosis
Am J Pathol 2000 157: 763-770. [Abstract] [Full Text]  

Gavin J. Gordon, William B. Coleman, and Joe W. Grisham

Temporal Analysis of Hepatocyte Differentiation by Small Hepatocyte-Like Progenitor Cells during Liver Regeneration in Retrorsine-Exposed Rats
Am J Pathol 2000 157: 771-786. [Abstract] [Full Text]  

Jan Richter, Urs Wagner, Juha Kononen, André Fijan, James Bruderer, Ulrico Schmid, Daniel Ackermann, Robert Maurer, Göran Alund, Hartmut Knönagel, Marcus Rist, Kim Wilber, Manuel Anabitarte, Franz Hering, Thomas Hardmeier, Andreas Schönenberger, Renata Flury, Peter Jäger, Jean Luc Fehr, Peter Schraml, Holger Moch, Michael J. Mihatsch, Thomas Gasser, Olli P. Kallioniemi, and Guido Sauter

High-Throughput Tissue Microarray Analysis of Cyclin E Gene Amplification and Overexpression in Urinary Bladder Cancer
Am J Pathol 2000 157: 787-794. [Abstract] [Full Text]  

Koh-ichi Nakashiro, Masato Okamoto, Yoshiki Hayashi, and Ryoichi Oyasu

Hepatocyte Growth Factor Secreted by Prostate-Derived Stromal Cells Stimulates Growth of Androgen-Independent Human Prostatic Carcinoma Cells
Am J Pathol 2000 157: 795-803. [Abstract] [Full Text]  

Paul J. Grippo and Eric P. Sandgren

Highly Invasive Transitional Cell Carcinoma of the Bladder in a Simian Virus 40 T-Antigen Transgenic Mouse Model
Am J Pathol 2000 157: 805-813. [Abstract] [Full Text]  

Junichiro Nishiyama, Shuzo Kobayashi, Aki Ishida, Iwao Nakabayashi, Osamu Tajima, Soichiro Miura, Masateru Katayama, and Haruo Nogami

Up-Regulation of Galectin-3 in Acute Renal Failure of the Rat
Am J Pathol 2000 157: 815-823. [Abstract] [Full Text]  

Julian R. Pratt, Katsushige Abe, Masanabu Miyazaki, Wuding Zhou, and Steven H. Sacks

In Situ Localization of C3 Synthesis in Experimental Acute Renal Allograft Rejection
Am J Pathol 2000 157: 825-831. [Abstract] [Full Text]  

Elena Torban, Michael Roger Eccles, Jack Favor, and Paul Rowland Goodyer

PAX2 Suppresses Apoptosis in Renal Collecting Duct Cells
Am J Pathol 2000 157: 833-842. [Abstract] [Full Text]  

Annarosa Leri, Fabio Fiordaliso, Manabu Setoguchi, Federica Limana, Nanette H. Bishopric, Jan Kajstura, Keith Webster, and Piero Anversa

Inhibition of p53 Function Prevents Renin-Angiotensin System Activation and Stretch-Mediated Myocyte Apoptosis
Am J Pathol 2000 157: 843-857. [Abstract] [Full Text]  

Jean-Francois Légaré, Thomas Issekutz, Timothy D. G. Lee, and Greg Hirsch

CD8+ T Lymphocytes Mediate Destruction of the Vascular Media in a Model of Chronic Rejection
Am J Pathol 2000 157: 859-865. [Abstract] [Full Text]  

Glenn M. LaMuraglia, Jan Schiereck, Joerg Heckenkamp, Giuseppe Nigri, Peter Waterman, Dariusz Leszczynski, and Sylvie Kossodo

Photodynamic Therapy Induces Apoptosis in Intimal Hyperplastic Arteries
Am J Pathol 2000 157: 867-875. [Abstract] [Full Text]  

W. Matthijs Blankesteijn, Mariëlle E. van Gijn, Yvonne P. G. Essers-Janssen, Mat J. A. P. Daemen, and Jos F. M. Smits

ß-Catenin, an Inducer of Uncontrolled Cell Proliferation and Migration in Malignancies, Is Localized in the Cytoplasm of Vascular Endothelium during Neovascularization after Myocardial Infarction
Am J Pathol 2000 157: 877-883. [Abstract] [Full Text]  

Narendra Vyavahare, Peter Lloyd Jones, Sruthi Tallapragada, and Robert J. Levy

Inhibition of Matrix Metalloproteinase Activity Attenuates Tenascin-C Production and Calcification of Implanted Purified Elastin in Rats
Am J Pathol 2000 157: 885-893. [Abstract] [Full Text]  

Greer M. Murphy Jr., Feifei Zhao, Lan Yang, and Barbara Cordell

Expression of Macrophage Colony-Stimulating Factor Receptor Is Increased in the AßPP^V717F Transgenic Mouse Model of Alzheimer’s Disease
Am J Pathol 2000 157: 895-904. [Abstract] [Full Text]  

Sim K. Singhrao, James W. Neal, Neil K. Rushmere, B. Paul Morgan, and Philippe Gasque

Spontaneous Classical Pathway Activation and Deficiency of Membrane Regulators Render Human Neurons Susceptible to Complement Lysis
Am J Pathol 2000 157: 905-918. [Abstract] [Full Text]  

Atsushi Tsugu, Keiichi Sakai, Peter B. Dirks, Shin Jung, Rosanna Weksberg, Yan-Ling Fei, Soma Mondal, Stacey Ivanchuk, Cameron Ackerley, Paul A. Hamel, and James T. Rutka

Expression of p57^KIP2 Potently Blocks the Growth of Human Astrocytomas and Induces Cell Senescence
Am J Pathol 2000 157: 919-932. [Abstract] [Full Text]  

Barbara Cannella, David Pitt, Elisabetta Capello, and Cedric S. Raine

Insulin-Like Growth Factor-1 Fails to Enhance Central Nervous System Myelin Repair during Autoimmune Demyelination
Am J Pathol 2000 157: 933-943. [Abstract] [Full Text]  

Matthias Hesse, Allen W. Cheever, Dragana Jankovic, and Thomas A. Wynn

NOS-2 Mediates the Protective Anti-Inflammatory and Antifibrotic Effects of the Th1-Inducing Adjuvant, IL-12, in a Th2 Model of Granulomatous Disease
Am J Pathol 2000 157: 945-955. [Abstract] [Full Text]  

Jari M. Karjalainen, Raija H. Tammi, Markku I. Tammi, Matti J. Eskelinen, Ulla M. Ågren, Jyrki J. Parkkinen, Esko M. Alhava, and Veli-Matti Kosma

Reduced Level of CD44 and Hyaluronan Associated with Unfavorable Prognosis in Clinical Stage I Cutaneous Melanoma
Am J Pathol 2000 157: 957-965. [Abstract] [Full Text]  

Boris C. Bastian, Philip E. LeBoit, and Daniel Pinkel

Mutations and Copy Number Increase of HRAS in Spitz Nevi with Distinctive Histopathological Features
Am J Pathol 2000 157: 967-972. [Abstract] [Full Text]  

J. Andrew Carlson, Kara Healy, Tien Anh Tran, John Malfetano, Vincent L. Wilson, Angela Rohwedder, and Jeffrey S. Ross

Chromosome 17 Aneusomy Detected by Fluorescence in Situ Hybridization in Vulvar Squamous Cell Carcinomas and Synchronous Vulvar Skin
Am J Pathol 2000 157: 973-983. [Abstract] [Full Text]  

Yasushi Yatabe, Hiroyuki Konishi, Tetsuya Mitsudomi, Shigeo Nakamura, and Takashi Takahashi

Topographical Distributions of Allelic Loss in Individual Non-Small-Cell Lung Cancers
Am J Pathol 2000 157: 985-993. [Abstract] [Full Text]  

Man Seong Seo, Naoyuki Okamoto, Melissa A. Vinores, Stanley A. Vinores, Sean F. Hackett, Haruhiko Yamada, Eri Yamada, Nancy L. Derevjanik, William LaRochelle, Donald J. Zack, and Peter A. Campochiaro

Photoreceptor-Specific Expression of Platelet-Derived Growth Factor-B Results in Traction Retinal Detachment
Am J Pathol 2000 157: 995-1005. [Abstract] [Full Text]  

Richard A. Zager and Thomas F. Kalhorn

Changes in Free and Esterified Cholesterol : Hallmarks of Acute Renal Tubular Injury and Acquired Cytoresistance
Am J Pathol 2000 157: 1007-1016. [Abstract] [Full Text]  

Animal Models:

Trudy A. Christiansen-Weber, Joseph R. Voland, Ying Wu, Karen Ngo, Barbara L. Roland, Steven Nguyen, Per A. Peterson, and Wai-Ping Fung-Leung

Functional Loss of ABCA1 in Mice Causes Severe Placental Malformation, Aberrant Lipid Distribution, and Kidney Glomerulonephritis As Well As High-Density Lipoprotein Cholesterol Deficiency
Am J Pathol 2000 157: 1017-1029. [Abstract] [Full Text]  

Eric C. Holland, Yi Li, Joseph Celestino, Chengkai Dai, Laura Schaefer, Raymond A. Sawaya, and Gregory N. Fuller

Astrocytes Give Rise to Oligodendrogliomas and Astrocytomas after Gene Transfer of Polyoma Virus Middle T Antigen in Vivo
Am J Pathol 2000 157: 1031-1037. [Abstract] [Full Text]  

Marcelo L. Rodriguez-Puebla, Margaret LaCava, Paula L. Miliani de Marval, Jose L. Jorcano, Ellen R. Richie, and Claudio J. Conti

Cyclin D2 Overexpression in Transgenic Mice Induces Thymic and Epidermal Hyperplasia whereas Cyclin D3 Expression Results Only in Epidermal Hyperplasia
Am J Pathol 2000 157: 1039-1050. [Abstract] [Full Text]  

Correspondence:

Boris Ruebner, Ramez Saroufeem, Byung Minutes, Henry Tesluk, Michael Lawson, John Thompson, Wolfgang Zimmermann, Georg Schwarzkopf, and Fritz Grunert

CEA Family Gene Expression and Ki67 Staining in Hyperplastic Polyps versus in Tubular Adenomas
Am J Pathol 2000 157: 1051-1052. [Full Text]  

Manuel Perucho, Shannon A. Kuismanen, Mari T. Holmberg, and Reijo Salovaara

Genetic and Epigenetic Modification of MLH1
Am J Pathol 2000 157: 1052-1053. [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.