Warner-Lambert/Parke-Davis Award Lecture:

John C. Reed

Mechanisms of Apoptosis
Am J Pathol 2000 157: 1415-1430. [Abstract] [Full Text]  

Short Communications:

Jianming Zhao, Roland R. de Krijger, Dorette Meier, Ernst-Jan M. Speel, Parvin Saremaslani, Seraina Muletta-Feurer, Claudia Matter, Jürgen Roth, Philipp U. Heitz, and Paul Komminoth

Genomic Alterations in Well-Differentiated Gastrointestinal and Bronchial Neuroendocrine Tumors (Carcinoids) : Marked Differences Indicating Diversity in Molecular Pathogenesis
Am J Pathol 2000 157: 1431-1438. [Abstract] [Full Text]  

John E. Duda, Benoit I. Giasson, Qiping Chen, Tamar L. Gur, Howard I. Hurtig, Matthew B. Stern, Steven M. Gollomp, Harry Ischiropoulos, Virginia M.-Y. Lee, and John Q. Trojanowski

Widespread Nitration of Pathological Inclusions in Neurodegenerative Synucleinopathies
Am J Pathol 2000 157: 1439-1445. [Abstract] [Full Text]  

Aimin Li, Suehiro Sakaguchi, Kazuto Shigematsu, Ryuichiro Atarashi, Bhabesh C. Roy, Ryota Nakaoke, Kazuhiko Arima, Nobuhiko Okimura, Juraj Kopacek, and Shigeru Katamine

Physiological Expression of the Gene for PrP-Like Protein, PrPLP/Dpl, by Brain Endothelial Cells and its Ectopic Expression in Neurons of PrP-Deficient Mice Ataxic Due to Purkinje Cell Degeneration
Am J Pathol 2000 157: 1447-1452. [Abstract] [Full Text]  

Bernd M. Spriewald, Masaki Hara, Andrew Bushell, Suzanne Jenkins, Peter J. Morris, and Kathryn J. Wood

Differential Role for Competitive Reverse Transcriptase-Polymerase Chain Reaction and Intracellular Cytokine Staining as Diagnostic Tools for the Assessment of Intragraft Cytokine Profiles in Rejecting and Nonrejecting Heart Allografts
Am J Pathol 2000 157: 1453-1458. [Abstract] [Full Text]  

Technical Advances:

Ludger Fink, Thomas Kinfe, Werner Seeger, Leander Ermert, Wolfgang Kummer, and Rainer Maria Bohle

Immunostaining for Cell Picking and Real-Time mRNA Quantitation
Am J Pathol 2000 157: 1459-1466. [Abstract] [Full Text]  

Minna Tanner, David Gancberg, Angelo Di Leo, Denis Larsimont, Ghizlane Rouas, Martine J. Piccart, and Jorma Isola

Chromogenic in Situ Hybridization : A Practical Alternative for Fluorescence in Situ Hybridization to Detect HER-2/neu Oncogene Amplification in Archival Breast Cancer Samples
Am J Pathol 2000 157: 1467-1472. [Abstract] [Full Text]  

Regular Articles:

Heike Beck, Till Acker, Christoph Wiessner, Peter R. Allegrini, and Karl H. Plate

Expression of Angiopoietin-1, Angiopoietin-2, and Tie Receptors after Middle Cerebral Artery Occlusion in the Rat
Am J Pathol 2000 157: 1473-1483. [Abstract] [Full Text]  

Anna G. Brunello, Jakob Weissenberger, Andreas Kappeler, Claudio Vallan, Malte Peters, Stefan Rose-John, and Joachim Weis

Astrocytic Alterations in Interleukin-6/Soluble Interleukin-6 Receptor Double-Transgenic Mice
Am J Pathol 2000 157: 1485-1493. [Abstract] [Full Text]  

Ina Tesseur, Jo Van Dorpe, Koen Bruynseels, Francisca Bronfman, Raf Sciot, Alfons Van Lommel, and Fred Van Leuven

Prominent Axonopathy and Disruption of Axonal Transport in Transgenic Mice Expressing Human Apolipoprotein E4 in Neurons of Brain and Spinal Cord
Am J Pathol 2000 157: 1495-1510. [Abstract] [Full Text]  

Daniela Renzi, Beatrice Pellegrini, Francesco Tonelli, Calogero Surrenti, and Antonio Calabrò

Substance P (Neurokinin-1) and Neurokinin A (Neurokinin-2) Receptor Gene and Protein Expression in the Healthy and Inflamed Human Intestine
Am J Pathol 2000 157: 1511-1522. [Abstract] [Full Text]  

Hiroki Kuniyasu, Wataru Yasui, Hisashi Shinohara, Seiji Yano, Lee M. Ellis, Michael R. Wilson, Corazon D. Bucana, Tadayoshi Rikita, Eiichi Tahara, and Isaiah J. Fidler

Induction of Angiogenesis by Hyperplastic Colonic Mucosa Adjacent to Colon Cancer
Am J Pathol 2000 157: 1523-1535. [Abstract] [Full Text]  

Debora Salani, Valeriana Di Castro, Maria Rita Nicotra, Laura Rosanò, Raffaele Tecce, Aldo Venuti, Pier Giorgio Natali, and Anna Bagnato

Role of Endothelin-1 in Neovascularization of Ovarian Carcinoma
Am J Pathol 2000 157: 1537-1547. [Abstract] [Full Text]  

Xi-Tao Wang, Yasushi Nagaba, Heide S. Cross, Fritz Wrba, Lin Zhang, and Sandra E. Guggino

The mRNA of L-Type Calcium Channel Elevated in Colon Cancer : Protein Distribution in Normal and Cancerous Colon
Am J Pathol 2000 157: 1549-1562. [Abstract] [Full Text]  

Vera J. M. Wielenga, Robbert van der Voort, Taher E. I. Taher, Lia Smit, Esther A. Beuling, Cees van Krimpen, Marcel Spaargaren, and Steven T. Pals

Expression of c-Met and Heparan-Sulfate Proteoglycan Forms of CD44 in Colorectal Cancer
Am J Pathol 2000 157: 1563-1573. [Abstract] [Full Text]  

Martin F. Fromm, Hans-Martin Kauffmann, Peter Fritz, Oliver Burk, Heyo K. Kroemer, Rolf W. Warzok, Michel Eichelbaum, Werner Siegmund, and Dieter Schrenk

The Effect of Rifampin Treatment on Intestinal Expression of Human MRP Transporters
Am J Pathol 2000 157: 1575-1580. [Abstract] [Full Text]  

Koji Isozaki, Benoit Terris, Jacques Belghiti, Serge Schiffmann, Seiichi Hirota, and Jean-Marie Vanderwinden

Germline-Activating Mutation in the Kinase Domain of KIT Gene in Familial Gastrointestinal Stromal Tumors
Am J Pathol 2000 157: 1581-1585. [Abstract] [Full Text]  

Judith V. M. G. Bovée, Martin van Royen, Alfons F. J. Bardoel, Carla Rosenberg, Cees J. Cornelisse, Anne-Marie Cleton-Jansen, and Pancras C. W. Hogendoorn

Near-Haploidy and Subsequent Polyploidization Characterize the Progression of Peripheral Chondrosarcoma
Am J Pathol 2000 157: 1587-1595. [Abstract] [Full Text]  

Marcus Rothe, Yon Ko, Peter Albers, and Nicolas Wernert

Eukaryotic Initiation Factor 3 p110 mRNA Is Overexpressed in Testicular Seminomas
Am J Pathol 2000 157: 1597-1604. [Abstract] [Full Text]  

Victor E. Gould, Nerea Martinez, Amila Orucevic, Jose Schneider, and Angel Alonso

A Novel, Nuclear Pore-Associated, Widely Distributed Molecule Overexpressed in Oncogenesis and Development
Am J Pathol 2000 157: 1605-1613. [Abstract] [Full Text]  

Victoria H. Mohr, Alexander O. Vortmeyer, Zhengping Zhuang, Steven K. Libutti, McClellan M. Walther, Peter L. Choyke, Berton Zbar, W. Marston Linehan, and Irina A. Lubensky

Histopathology and Molecular Genetics of Multiple Cysts and Microcystic (Serous) Adenomas of the Pancreas in von Hippel-Lindau Patients
Am J Pathol 2000 157: 1615-1621. [Abstract] [Full Text]  

Hong Ouyang, Lun-jun Mou, Catherine Luk, Ni Liu, Jana Karaskova, Jeremy Squire, and Ming-Sound Tsao

Immortal Human Pancreatic Duct Epithelial Cell Lines with Near Normal Genotype and Phenotype
Am J Pathol 2000 157: 1623-1631. [Abstract] [Full Text]  

Su P. Yang, Adrian S. Woolf, Hai T. Yuan, Rosemary J. Scott, R. Anthony Risdon, Michael J. O’Hare, and Paul J. D. Winyard

Potential Biological Role of Transforming Growth Factor-ß1 in Human Congenital Kidney Malformations
Am J Pathol 2000 157: 1633-1647. [Abstract] [Full Text]  

Dominic Cosgrove, Kathryn Rodgers, Daniel Meehan, Caroline Miller, Karen Bovard, Amy Gilroy, Humphrey Gardner, Victor Kotelianski, Phillip Gotwals, Aldo Amatucci, and Raghu Kalluri

Integrin 1ß1 and Transforming Growth Factor-ß1 Play Distinct Roles in Alport Glomerular Pathogenesis and Serve as Dual Targets for Metabolic Therapy
Am J Pathol 2000 157: 1649-1659. [Abstract] [Full Text]  

Thinle Chodon, Tsuneki Sugihara, Hiroharu H. Igawa, Emi Funayama, and Hiroshi Furukawa

Keloid-Derived Fibroblasts Are Refractory to Fas-Mediated Apoptosis and Neutralization of Autocrine Transforming Growth Factor-ß1 Can Abrogate this Resistance
Am J Pathol 2000 157: 1661-1669. [Abstract] [Full Text]  

Jens Schümann, Dominik Wolf, Andreas Pahl, Kay Brune, Thomas Papadopoulos, Nico van Rooijen, and Gisa Tiegs

Importance of Kupffer Cells for T-Cell-Dependent Liver Injury in Mice
Am J Pathol 2000 157: 1671-1683. [Abstract] [Full Text]  

Filomena Conti, Sylvie Breton, Frédéric Batteux, Valérie Furlan, Didier Houssin, Bernard Weill, and Yvon Calmus

Defective Interleukin-1 Receptor Antagonist Production Is Associated with Resistance of Acute Liver Graft Rejection to Steroid Therapy
Am J Pathol 2000 157: 1685-1692. [Abstract] [Full Text]  

Tomoaki Tomiya, Itsuro Ogata, Miho Yamaoka, Mikio Yanase, Yukiko Inoue, and Kenji Fujiwara

The Mitogenic Activity of Hepatocyte Growth Factor on Rat Hepatocytes Is Dependent upon Endogenous Transforming Growth Factor-
Am J Pathol 2000 157: 1693-1701. [Abstract] [Full Text]  

Debora Salani, Giulia Taraboletti, Laura Rosanò, Valeriana Di Castro, Patrizia Borsotti, Raffaella Giavazzi, and Anna Bagnato

Endothelin-1 Induces an Angiogenic Phenotype in Cultured Endothelial Cells and Stimulates Neovascularization In Vivo
Am J Pathol 2000 157: 1703-1711. [Abstract] [Full Text]  

Benedetta Bussolati, Luigi Biancone, Paola Cassoni, Simona Russo, Marek Rola-Pleszczynski, Giuseppe Montrucchio, and Giovanni Camussi

PAF Produced by Human Breast Cancer Cells Promotes Migration and Proliferation of Tumor Cells and Neo-Angiogenesis
Am J Pathol 2000 157: 1713-1725. [Abstract] [Full Text]  

Elda Perlino, Mariarosaria Lovecchio, Rosa A. Vacca, Mara Fornaro, Loredana Moro, Pasquale Ditonno, Michele Battaglia, Francesco P. Selvaggi, Mauro G. Mastropasqua, Pantaleo Bufo, and Lucia R. Languino

Regulation of mRNA and Protein Levels of ß1 Integrin Variants in Human Prostate Carcinoma
Am J Pathol 2000 157: 1727-1734. [Abstract] [Full Text]  

Susan M. Koethe, John R. Kuhnmuench, and Carl G. Becker

Neutrophil Priming by Cigarette Smoke Condensate and a Tobacco Anti-Idiotypic Antibody
Am J Pathol 2000 157: 1735-1743. [Abstract] [Full Text]  

Jesper J. Hedberg, Jan-Olov Höög, Jan A. Nilsson, Zheng Xi, Åsa Elfwing, and Roland C. Grafström

Expression of Alcohol Dehydrogenase 3 in Tissue and Cultured Cells from Human Oral Mucosa
Am J Pathol 2000 157: 1745-1755. [Abstract] [Full Text]  

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