Editorials:

Nelson Fausto

Editor’s Farewell
Am J Pathol 2000 157: 1757-1758. [Full Text]  

Commentaries:

Harvey Jon Kliman

Uteroplacental Blood Flow : The Story of Decidualization, Menstruation, and Trophoblast Invasion
Am J Pathol 2000 157: 1759-1768. [Full Text]  

Short Communications:

Sabina Signoretti, David Waltregny, James Dilks, Beth Isaac, Douglas Lin, Levi Garraway, Annie Yang, Rodolfo Montironi, Frank McKeon, and Massimo Loda

p63 Is a Prostate Basal Cell Marker and Is Required for Prostate Development
Am J Pathol 2000 157: 1769-1775. [Abstract] [Full Text]  

Michael E. Kupferman, M. Elizabeth Fini, William J. Muller, Randal Weber, Yi Cheng, and Ruth J. Muschel

Matrix Metalloproteinase 9 Promoter Activity Is Induced Coincident with Invasion during Tumor Progression
Am J Pathol 2000 157: 1777-1783. [Abstract] [Full Text]  

Kathrin D. Geiger, Peter Stoldt, Wolfgang Schlote, and Amin Derouiche

Ezrin Immunoreactivity Is Associated with Increasing Malignancy of Astrocytic Tumors but Is Absent in Oligodendrogliomas
Am J Pathol 2000 157: 1785-1793. [Abstract] [Full Text]  

Milam A. Brantley Jr. and J. William Harbour

Deregulation of the Rb and p53 Pathways in Uveal Melanoma
Am J Pathol 2000 157: 1795-1801. [Abstract] [Full Text]  

Lisa L. P. Siu, Vivian Chan, John K. C. Chan, Kit-Fai Wong, Raymond Liang, and Yok-Lam Kwong

Consistent Patterns of Allelic Loss in Natural Killer Cell Lymphoma
Am J Pathol 2000 157: 1803-1809. [Abstract] [Full Text]  

Homira Behbahani, Edwina Popek, Patricia Garcia, Jan Andersson, Anna-Lena Spetz, Alan Landay, Zareefa Flener, and Bruce K. Patterson

Up-Regulation of CCR5 Expression in the Placenta Is Associated with Human Immunodeficiency Virus-1 Vertical Transmission
Am J Pathol 2000 157: 1811-1818. [Abstract] [Full Text]  

Stewart C. Whitman, Punnaivanam Ravisankar, Haley Elam, and Alan Daugherty

Exogenous Interferon- Enhances Atherosclerosis in Apolipoprotein E-/- Mice
Am J Pathol 2000 157: 1819-1824. [Abstract] [Full Text]  

Michiko Miyaki, Takeru Iijima, Reiko Ishii, Tsunekazu Hishima, Takeo Mori, Keigo Yoshinaga, Hiroshi Takami, Toshio Kuroki, and Takeo Iwama

Molecular Evidence for Multicentric Development of Thyroid Carcinomas in Patients with Familial Adenomatous Polyposis
Am J Pathol 2000 157: 1825-1827. [Abstract] [Full Text]  

Technical Advances:

Marcus Mueller, Karin Wacker, William F. Hickey, Erich B. Ringelstein, and Reinhard Kiefer

Co-Localization of Multiple Antigens and Specific DNA : A Novel Method Using Methyl Methacrylate-Embedded Semithin Serial Sections and Catalyzed Reporter Deposition
Am J Pathol 2000 157: 1829-1838. [Abstract] [Full Text]  

Regular Articles:

Binghua Zhu, David G. Kuhel, David P. Witte, and David Y. Hui

Apolipoprotein E Inhibits Neointimal Hyperplasia after Arterial Injury in Mice
Am J Pathol 2000 157: 1839-1848. [Abstract] [Full Text]  

Jonathan H. Erlich, Edward M. Boyle, Joanne Labriola, J. Craig Kovacich, Richard A. Santucci, Colleen Fearns, Elizabeth N. Morgan, Wang Yun, Thomas Luther, Osamu Kojikawa, Thomas R. Martin, Timothy H. Pohlman, Edward D. Verrier, and Nigel Mackman

Inhibition of the Tissue Factor-Thrombin Pathway Limits Infarct Size after Myocardial Ischemia-Reperfusion Injury by Reducing Inflammation
Am J Pathol 2000 157: 1849-1862. [Abstract] [Full Text]  

Giorgia Egidy, Lucienne Juillerat-Jeanneret, Jean-François Jeannin, Petra Korth, Fred T. Bosman, and Florence Pinet

Modulation of Human Colon Tumor-Stromal Interactions by the Endothelin System
Am J Pathol 2000 157: 1863-1874. [Abstract] [Full Text]  

Reiko Inada, Masato Matsuki, Keiko Yamada, Yoichi Morishima, Shen-Chun Shen, Nobuo Kuramoto, Hirokazu Yasuno, Kenzo Takahashi, Yoshiki Miyachi, and Kiyofumi Yamanishi

Facilitated Wound Healing by Activation of the Transglutaminase 1 Gene
Am J Pathol 2000 157: 1875-1882. [Abstract] [Full Text]  

Manuela M. Santos, Maria de Sousa, Luke H. P. M. Rademakers, Hans Clevers, J. J. M. Marx, and Marco W. Schilham

Iron Overload and Heart Fibrosis in Mice Deficient for Both ß2-Microglobulin and Rag1
Am J Pathol 2000 157: 1883-1892. [Abstract] [Full Text]  

Seiji Yano, Hisashi Shinohara, Roy S. Herbst, Hiroki Kuniyasu, Corazon D. Bucana, Lee M. Ellis, and Isaiah J. Fidler

Production of Experimental Malignant Pleural Effusions Is Dependent on Invasion of the Pleura and Expression of Vascular Endothelial Growth Factor/Vascular Permeability Factor by Human Lung Cancer Cells
Am J Pathol 2000 157: 1893-1903. [Abstract] [Full Text]  

Vesa Ruotsalainen, Jaakko Patrakka, Päivi Tissari, Paula Reponen, Michael Hess, Marjo Kestilä, Christer Holmberg, Riitta Salonen, Markku Heikinheimo, Jorma Wartiovaara, Karl Tryggvason, and Hannu Jalanko

Role of Nephrin in Cell Junction Formation in Human Nephrogenesis
Am J Pathol 2000 157: 1905-1916. [Abstract] [Full Text]  

Vibeke Westphal, Simon Murch, Soohyun Kim, Geetha Srikrishna, Bryan Winchester, Richard Day, and Hudson H. Freeze

Reduced Heparan Sulfate Accumulation in Enterocytes Contributes to Protein-Losing Enteropathy in a Congenital Disorder of Glycosylation
Am J Pathol 2000 157: 1917-1925. [Abstract] [Full Text]  

John F. Tarlton, Christine V. Whiting, David Tunmore, Soren Bregenholt, Jorg Reimann, Mogens H. Claesson, and Paul W. Bland

The Role of Up-Regulated Serine Proteases and Matrix Metalloproteinases in the Pathogenesis of a Murine Model of Colitis
Am J Pathol 2000 157: 1927-1935. [Abstract] [Full Text]  

Kenneth R. LaMontagne Jr., Marsha A. Moses, Dmitri Wiederschain, Sudipta Mahajan, Jeannine Holden, Hamid Ghazizadeh, David A. Frank, and Jack L. Arbiser

Inhibition of MAP Kinase Kinase Causes Morphological Reversion and Dissociation between Soft Agar Growth and in Vivo Tumorigenesis in Angiosarcoma Cells
Am J Pathol 2000 157: 1937-1945. [Abstract] [Full Text]  

Richard Palmqvist, Jörgen N. Rutegård, Bela Bozoky, Göran Landberg, and Roger Stenling

Human Colorectal Cancers with an Intact p16/Cyclin D1/pRb Pathway Have Up-Regulated p16 Expression and Decreased Proliferation in Small Invasive Tumor Clusters
Am J Pathol 2000 157: 1947-1953. [Abstract] [Full Text]  

Sylvia L. F. Pender, Mikko T. Salmela, Giovanni Monteleone, Denni Schnapp, Catriona McKenzie, Jo Spencer, Sherman Fong, Ulpu Saarialho-Kere, and Thomas T. MacDonald

Ligation of 4ß1 Integrin on Human Intestinal Mucosal Mesenchymal Cells Selectively Up-Regulates Membrane Type-1 Matrix Metalloproteinase and Confers a Migratory Phenotype
Am J Pathol 2000 157: 1955-1962. [Abstract] [Full Text]  

Teresa C. Weglarz, Jay L. Degen, and Eric P. Sandgren

Hepatocyte Transplantation into Diseased Mouse Liver : Kinetics of Parenchymal Repopulation and Identification of the Proliferative Capacity of Tetraploid and Octaploid Hepatocytes
Am J Pathol 2000 157: 1963-1974. [Abstract] [Full Text]  

Allal Ouhtit, Alexander Gorny, H. Konrad Muller, Laurie L. Hill, Laurie Owen-Schaub, and Honnavara N. Ananthaswamy

Loss of Fas-Ligand Expression in Mouse Keratinocytes during UV Carcinogenesis
Am J Pathol 2000 157: 1975-1981. [Abstract] [Full Text]  

Xiao-Ling Ding, Jacob Husseman, Andrei Tomashevski, David Nochlin, Lee-Way Jin, and Inez Vincent

The Cell Cycle Cdc25A Tyrosine Phosphatase Is Activated in Degenerating Postmitotic Neurons in Alzheimer’s Disease
Am J Pathol 2000 157: 1983-1990. [Abstract] [Full Text]  

Barbara Serafini, Sandra Columba-Cabezas, Francesca Di Rosa, and Francesca Aloisi

Intracerebral Recruitment and Maturation of Dendritic Cells in the Onset and Progression of Experimental Autoimmune Encephalomyelitis
Am J Pathol 2000 157: 1991-2002. [Abstract] [Full Text]  

Lennart Mucke, Gui-Qiu Yu, Lisa McConlogue, Edward M. Rockenstein, Carmela R. Abraham, and Eliezer Masliah

Astroglial Expression of Human ₁-Antichymotrypsin Enhances Alzheimer-like Pathology in Amyloid Protein Precursor Transgenic Mice
Am J Pathol 2000 157: 2003-2010. [Abstract] [Full Text]  

Annukka Paju, Anders Bjartell, Wan-Ming Zhang, Stig Nordling, Anders Borgström, Jens Hansson, and Ulf-Håkan Stenman

Expression and Characterization of Trypsinogen Produced in the Human Male Genital Tract
Am J Pathol 2000 157: 2011-2021. [Abstract] [Full Text]  

Prosper N. Boyaka, Peter F. Wright, Mariarosaria Marinaro, Hiroshi Kiyono, Joyce E. Johnson, Ricardo A. Gonzales, Mine R. Ikizler, Jay A. Werkhaven, Raymond J. Jackson, Kohtaro Fujihashi, Simonetta Di Fabio, Herman F. Staats, and Jerry R. McGhee

Human Nasopharyngeal-Associated Lymphoreticular Tissues : Functional Analysis of Subepithelial and Intraepithelial B and T Cells from Adenoids and Tonsils
Am J Pathol 2000 157: 2023-2035. [Abstract] [Full Text]  

Auragun Wibulswas, Daniel Croft, Ian Bacarese-Hamilton, Peter McIntyre, Elisabeth Genot, and IJsbrand M. Kramer

The CD44v7/8 Epitope as a Target to Restrain Proliferation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
Am J Pathol 2000 157: 2037-2044. [Abstract] [Full Text]  

J. Clifford Murray, Georgina Barnett, Maarten Tas, Anne Jakobsen, Joanne Brown, Des Powe, and Colin Clelland

Immunohistochemical Analysis of Endothelial-Monocyte-Activating Polypeptide-II Expression in Vivo
Am J Pathol 2000 157: 2045-2053. [Abstract] [Full Text]  

Xiaozhou Shang, Boqin Qiu, Kirsten A. Frait, Jerry S. Hu, Joanne Sonstein, Jeffrey L. Curtis, Bao Lu, Craig Gerard, and Stephen W. Chensue

Chemokine Receptor 1 Knockout Abrogates Natural Killer Cell Recruitment and Impairs Type-1 Cytokines in Lymphoid Tissue during Pulmonary Granuloma Formation
Am J Pathol 2000 157: 2055-2063. [Abstract] [Full Text]  

Salvatore Cuzzocrea, Michelle C. McDonald, Emanuela Mazzon, Dilani Siriwardena, Ivana Serraino, Laura Dugo, Domenico Britti, Giuseppe Mazzullo, Achille P. Caputi, and Christoph Thiemermann

Calpain Inhibitor I Reduces the Development of Acute and Chronic Inflammation
Am J Pathol 2000 157: 2065-2079. [Abstract] [Full Text]  

Alfons S. K. de Hooge, Fons A. J. van de Loo, Onno J. Arntz, and Wim B. van den Berg

Involvement of IL-6, Apart from Its Role in Immunity, in Mediating a Chronic Response during Experimental Arthritis
Am J Pathol 2000 157: 2081-2091. [Abstract] [Full Text]  

Maho Morishima-Kawashima, Noriko Oshima, Hiromitsu Ogata, Haruyasu Yamaguchi, Masahiro Yoshimura, Shiro Sugihara, and Yasuo Ihara

Effect of Apolipoprotein E Allele 4 on the Initial Phase of Amyloid ß-Protein Accumulation in the Human Brain
Am J Pathol 2000 157: 2093-2099. [Abstract] [Full Text]  

Setsuya Sakagashira, Henry J. Hiddinga, Kayoko Tateishi, Tokio Sanke, Tadashi Hanabusa, Kishio Nanjo, and Norman L. Eberhardt

S20G Mutant Amylin Exhibits Increased in Vitro Amyloidogenicity and Increased Intracellular Cytotoxicity Compared to Wild-Type Amylin
Am J Pathol 2000 157: 2101-2109. [Abstract] [Full Text]  

Eric Jauniaux, Adrian L. Watson, Joanne Hempstock, Yi-Ping Bao, Jeremy N. Skepper, and Graham J. Burton

Onset of Maternal Arterial Blood Flow and Placental Oxidative Stress : A Possible Factor in Human Early Pregnancy Failure
Am J Pathol 2000 157: 2111-2122. [Abstract] [Full Text]  

Lorena Landuzzi, Carla De Giovanni, Giordano Nicoletti, Ilaria Rossi, Cinzia Ricci, Annalisa Astolfi, Luciano Scopece, Katia Scotlandi, Massimo Serra, Gian Paolo Bagnara, Patrizia Nanni, and Pier-Luigi Lollini

The Metastatic Ability of Ewing’s Sarcoma Cells Is Modulated by Stem Cell Factor and by Its Receptor c-kit
Am J Pathol 2000 157: 2123-2131. [Abstract] [Full Text]  

Takehisa Hashimoto, Yoshio Tokuchi, Moriaki Hayashi, Yasuhito Kobayashi, Kazunori Nishida, Shin-ichi Hayashi, Yuichi Ishikawa, Ken Nakagawa, Jun-ichi Hayashi, and Eiju Tsuchiya

Different Subtypes of Human Lung Adenocarcinoma Caused by Different Etiological Factors : Evidence from p53 Mutational Spectra
Am J Pathol 2000 157: 2133-2141. [Abstract] [Full Text]  

Animal Models:

Margarethe Hoenig, Gregory Hall, Duncan Ferguson, Katherine Jordan, Michael Henson, Kenneth Johnson, and Timothy O’Brien

A Feline Model of Experimentally Induced Islet Amyloidosis
Am J Pathol 2000 157: 2143-2150. [Abstract] [Full Text]  

Charlotte Kuperwasser, Gregory D. Hurlbut, Frances S. Kittrell, Ellen S. Dickinson, Rudy Laucirica, Daniel Medina, Stephen P. Naber, and D. Joseph Jerry

Development of Spontaneous Mammary Tumors in BALB/c p53 Heterozygous Mice : A Model for Li-Fraumeni Syndrome
Am J Pathol 2000 157: 2151-2159. [Abstract] [Full Text]  

Correction:

Correction
Am J Pathol 2000 157: 2161. [Full Text]  

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