This Month in AJP:

The Role of Genetic Instability in Tumor Growth: Challenge of a Concept
Am J Pathol 2002 160: 753-754. [Full Text]  

Commentaries:

Ian Tomlinson, Peter Sasieni, and Walter Bodmer

How Many Mutations in a Cancer?
Am J Pathol 2002 160: 755-758. [Full Text]  

Jon C. Aster and Janina A. Longtine

Detection of BCL2 Rearrangements in Follicular Lymphoma
Am J Pathol 2002 160: 759-763. [Full Text]  

Short Communications:

Hirokazu Okada, Tsutomu Inoue, Yoshihiko Kanno, Tatsuya Kobayashi, Yusuke Watanabe, Jeffrey B. Kopp, Robert M. Carey, and Hiromichi Suzuki

Interstitial Fibroblast-Like Cells Express Renin-Angiotensin System Components in a Fibrosing Murine Kidney
Am J Pathol 2002 160: 765-772. [Abstract] [Full Text]  

Peter Hewett, Sarbjit Nijjar, Munjiba Shams, Susan Morgan, Janesh Gupta, and Asif Ahmed

Down-Regulation of Angiopoietin-1 Expression in Menorrhagia
Am J Pathol 2002 160: 773-780. [Abstract] [Full Text]  

Yan-Jun Gan, Bassem I. Razzouk, Tao Su, and John W. Sixbey

A Defective, Rearranged Epstein-Barr Virus Genome in EBER-Negative and EBER-Positive Hodgkin’s Disease
Am J Pathol 2002 160: 781-786. [Abstract] [Full Text]  

Gyeong Hoon Kang, Sun Lee, Woo Ho Kim, Hye Won Lee, Jin Cheon Kim, Mun-Gan Rhyu, and Jae Y. Ro

Epstein-Barr Virus-Positive Gastric Carcinoma Demonstrates Frequent Aberrant Methylation of Multiple Genes and Constitutes CpG Island Methylator Phenotype-Positive Gastric Carcinoma
Am J Pathol 2002 160: 787-794. [Abstract] [Full Text]  

Michele A. Zysman, William B. Chapman, and Bharati Bapat

Considerations When Analyzing the Methylation Status of PTEN Tumor Suppressor Gene
Am J Pathol 2002 160: 795-800. [Abstract] [Full Text]  

Technical Advances:

Stefan J. Scheidl, Sven Nilsson, Mattias Kalén, Mats Hellström, Minoru Takemoto, Joakim Håkansson, and Per Lindahl

mRNA Expression Profiling of Laser Microbeam Microdissected Cells from Slender Embryonic Structures
Am J Pathol 2002 160: 801-813. [Abstract] [Full Text]  

Rachel A. Craven, Nick Totty, Patricia Harnden, Peter J. Selby, and Rosamonde E. Banks

Laser Capture Microdissection and Two-Dimensional Polyacrylamide Gel Electrophoresis : Evaluation of Tissue Preparation and Sample Limitations
Am J Pathol 2002 160: 815-822. [Abstract] [Full Text]  

Andrea Albinger-Hegyi, Bernhard Hochreutener, Marie-Therese Abdou, Ivan Hegyi, María Teresa Dours-Zimmermann, Michael O. Kurrer, Philipp U. Heitz, and Dieter R. Zimmermann

High Frequency of t(14;18)-Translocation Breakpoints Outside of Major Breakpoint and Minor Cluster Regions in Follicular Lymphomas : Improved Polymerase Chain Reaction Protocols for Their Detection
Am J Pathol 2002 160: 823-832. [Abstract] [Full Text]  

Regular Articles:

Christine A. Kostek, Janice A. Dominov, and Jeffrey Boone Miller

Up-Regulation of MHC Class I Expression Accompanies but Is Not Required for Spontaneous Myopathy in Dysferlin-Deficient SJL/J Mice
Am J Pathol 2002 160: 833-839. [Abstract] [Full Text]  

Taunia D. Lee, Melva L. Gonzalez, Padmasini Kumar, Saritha Chary-Reddy, Paula Grammas, and H. Anne Pereira

CAP37, a Novel Inflammatory Mediator : Its Expression in Endothelial Cells and Localization to Atherosclerotic Lesions
Am J Pathol 2002 160: 841-848. [Abstract] [Full Text]  

Maria Cristina Manara, Bernard Perbal, Stefania Benini, Rosaria Strammiello, Vanessa Cerisano, Stefania Perdichizzi, Massimo Serra, Annalisa Astolfi, Franco Bertoni, Jennifer Alami, Herman Yeger, Piero Picci, and Katia Scotlandi

The Expression of ccn3(nov) Gene in Musculoskeletal Tumors
Am J Pathol 2002 160: 849-859. [Abstract] [Full Text]  

Andrea Hartner, Nada Cordasic, Bernd Klanke, Ulrich Müller, R. Bernd Sterzel, and Karl F. Hilgers

The 8 Integrin Chain Affords Mechanical Stability to the Glomerular Capillary Tuft in Hypertensive Glomerular Disease
Am J Pathol 2002 160: 861-867. [Abstract] [Full Text]  

Tokushige Kobayashi, Futoshi Okada, Nobuyuki Fujii, Naoko Tomita, Satoru Ito, Hiroshi Tazawa, Tetsuya Aoyama, Sung Ki Choi, Toshiyuki Shibata, Hisakazu Fujita, and Masuo Hosokawa

Thymosin-ß4 Regulates Motility and Metastasis of Malignant Mouse Fibrosarcoma Cells
Am J Pathol 2002 160: 869-882. [Abstract] [Full Text]  

Wilhelmina M. Aarts, Richard J. Bende, Jan-Willem Vaandrager, Philip M. Kluin, Anton W. Langerak, Steven T. Pals, and Carel J.M. van Noesel

In Situ Analysis of the Variable Heavy Chain Gene of an IgM/IgG-Expressing Follicular Lymphoma : Evidence for Interfollicular Trafficking of Tumor Cells
Am J Pathol 2002 160: 883-891. [Abstract] [Full Text]  

Carsten Denkert, Martin Köbel, Sören Pest, Ines Koch, Stefan Berger, Michael Schwabe, Antje Siegert, Angela Reles, Bernd Klosterhalfen, and Steffen Hauptmann

Expression of Cyclooxygenase 2 Is an Independent Prognostic Factor in Human Ovarian Carcinoma
Am J Pathol 2002 160: 893-903. [Abstract] [Full Text]  

Janet Liversidge, Andrew Dick, and Sharon Gordon

Nitric Oxide Mediates Apoptosis Through Formation of Peroxynitrite and Fas/Fas-Ligand Interactions in Experimental Autoimmune Uveitis
Am J Pathol 2002 160: 905-916. [Abstract] [Full Text]  

Andrew D. Cook, Emma L. Braine, Ian K. Campbell, and John A. Hamilton

Differing Roles for Urokinase and Tissue-Type Plasminogen Activator in Collagen-Induced Arthritis
Am J Pathol 2002 160: 917-926. [Abstract] [Full Text]  

Stephanie J. Bissel, Guoji Wang, Mimi Ghosh, Todd A. Reinhart, Saverio Capuano, III, Kelly Stefano Cole, Michael Murphey-Corb, Michael Piatak, Jr., Jeffrey D. Lifson, and Clayton A. Wiley

Macrophages Relate Presynaptic and Postsynaptic Damage in Simian Immunodeficiency Virus Encephalitis
Am J Pathol 2002 160: 927-941. [Abstract] [Full Text]  

Manolis Mavroidis and Yassemi Capetanaki

Extensive Induction of Important Mediators of Fibrosis and Dystrophic Calcification in Desmin-Deficient Cardiomyopathy
Am J Pathol 2002 160: 943-952. [Abstract] [Full Text]  

Susan C. Abraham, Tsung-Teh Wu, Ralph H. Hruban, Jae-Hyuk Lee, Charles J. Yeo, Kevin Conlon, Murray Brennan, John L. Cameron, and David S. Klimstra

Genetic and Immunohistochemical Analysis of Pancreatic Acinar Cell Carcinoma : Frequent Allelic Loss on Chromosome 11p and Alterations in the APC/ß-Catenin Pathway
Am J Pathol 2002 160: 953-962. [Abstract] [Full Text]  

Dolgor Baatar, Michael K. Jones, Rama Pai, Hirofumi Kawanaka, Imre L. Szabo, Woo S. Moon, Seigo Kitano, and Andrzej S. Tarnawski

Selective Cyclooxygenase-2 Blocker Delays Healing of Esophageal Ulcers in Rats and Inhibits Ulceration-Triggered c-Met/Hepatocyte Growth Factor Receptor Induction and Extracellular Signal-Regulated Kinase 2 Activation
Am J Pathol 2002 160: 963-972. [Abstract] [Full Text]  

Véronique Chauvet, Feng Qian, Nicolas Boute, Yiqiang Cai, Bunyong Phakdeekitacharoen, Luis F. Onuchic, Tania Attié-Bitach, Liliane Guicharnaud, Olivier Devuyst, Gregory G. Germino, and Marie-Claire Gubler

Expression of PKD1 and PKD2 Transcripts and Proteins in Human Embryo and during Normal Kidney Development
Am J Pathol 2002 160: 973-983. [Abstract] [Full Text]  

Shunichi Morikawa, Peter Baluk, Toshiyuki Kaidoh, Amy Haskell, Rakesh K. Jain, and Donald M. McDonald

Abnormalities in Pericytes on Blood Vessels and Endothelial Sprouts in Tumors
Am J Pathol 2002 160: 985-1000. [Abstract] [Full Text]  

Eckart Laack, Haleh Nikbakht, Anja Peters, Christian Kugler, Yvonne Jasiewicz, Lutz Edler, Dieter Kurt Hossfeld, and Udo Schumacher

Lectin Histochemistry of Resected Adenocarcinoma of the Lung : Helix pomatia Agglutinin Binding Is an Independent Prognostic Factor
Am J Pathol 2002 160: 1001-1008. [Abstract] [Full Text]  

Oddbjørn Straume and Lars Andreas Akslen

Importance of Vascular Phenotype by Basic Fibroblast Growth Factor, and Influence of the Angiogenic Factors Basic Fibroblast Growth Factor/Fibroblast Growth Factor Receptor-1 and Ephrin-A1/EphA2 on Melanoma Progression
Am J Pathol 2002 160: 1009-1019. [Abstract] [Full Text]  

Takayuki Iwaki, Mayra J. Sandoval-Cooper, Melissa Paiva, Takao Kobayashi, Victoria A. Ploplis, and Francis J. Castellino

Fibrinogen Stabilizes Placental-Maternal Attachment During Embryonic Development in the Mouse
Am J Pathol 2002 160: 1021-1034. [Abstract] [Full Text]  

Sigrid Regauer, Olaf Reich, and Christine Beham-Schmid

Monoclonal -T-Cell Receptor Rearrangement in Vulvar Lichen Sclerosus and Squamous Cell Carcinomas
Am J Pathol 2002 160: 1035-1045. [Abstract] [Full Text]  

Wei Qu, Bhalchandra A. Diwan, Jie Liu, Robert A. Goyer, Tammy Dawson, John L. Horton, M. George Cherian, and Michael P. Waalkes

The Metallothionein-Null Phenotype Is Associated with Heightened Sensitivity to Lead Toxicity and an Inability to Form Inclusion Bodies
Am J Pathol 2002 160: 1047-1056. [Abstract] [Full Text]  

Kathleen C. Flanders, Catherine D. Sullivan, Makiko Fujii, Anastasia Sowers, Mario A. Anzano, Alidad Arabshahi, Christopher Major, Chuxia Deng, Angelo Russo, James B. Mitchell, and Anita B. Roberts

Mice Lacking Smad3 Are Protected Against Cutaneous Injury Induced by Ionizing Radiation
Am J Pathol 2002 160: 1057-1068. [Abstract] [Full Text]  

Young K. Song, Timothy R. Billiar, and Yong J. Lee

Role of Galectin-3 in Breast Cancer Metastasis : Involvement of Nitric Oxide
Am J Pathol 2002 160: 1069-1075. [Abstract] [Full Text]  

Yutaka Furukawa, Peter Libby, Jennifer L. Stinn, Gerold Becker, and Richard N. Mitchell

Cold Ischemia Induces Isograft Arteriopathy, but Does Not Augment Allograft Arteriopathy in Non-Immunosuppressed Hosts
Am J Pathol 2002 160: 1077-1087. [Abstract] [Full Text]  

Michelle P. Bendeck, Michelle Conte, Mingyu Zhang, Nafiseh Nili, Bradley H. Strauss, and Stephanie M. Farwell

Doxycycline Modulates Smooth Muscle Cell Growth, Migration, and Matrix Remodeling after Arterial Injury
Am J Pathol 2002 160: 1089-1095. [Abstract] [Full Text]  

Jeremy Griggs, Jeremy N. Skepper, Gerry A. Smith, Kevin M. Brindle, James C. Metcalfe, and Robin Hesketh

Inhibition of Proliferative Retinopathy by the Anti-Vascular Agent Combretastatin-A4
Am J Pathol 2002 160: 1097-1103. [Abstract] [Full Text]  

Christian H. Rickert, Otmar D. Wiestler, and Werner Paulus

Chromosomal Imbalances in Choroid Plexus Tumors
Am J Pathol 2002 160: 1105-1113. [Abstract] [Full Text]  

Jay A. A. West, Kurt J. Williams, Elina Toskala, Susan J. Nishio, Chad A. Fleschner, Henry Jay Forman, Alan R. Buckpitt, and Charles G. Plopper

Induction of Tolerance to Naphthalene in Clara Cells Is Dependent on a Stable Phenotypic Adaptation Favoring Maintenance of the Glutathione Pool
Am J Pathol 2002 160: 1115-1127. [Abstract] [Full Text]  

Toshiro Niki, Takashi Kohno, Sanae Iba, Yasumitsu Moriya, Yoko Takahashi, Miyuki Saito, Arafumi Maeshima, Tesshi Yamada, Yoshihiro Matsuno, Masashi Fukayama, Jun Yokota, and Setsuo Hirohashi

Frequent Co-Localization of Cox-2 and Laminin-5 2 Chain at the Invasive Front of Early-Stage Lung Adenocarcinomas
Am J Pathol 2002 160: 1129-1141. [Abstract] [Full Text]  

Animal Models:

Antoinette Wetterwald, Gabri van der Pluijm, Ivo Que, Bianca Sijmons, Jeroen Buijs, Marcel Karperien, Clemens W. G. M. Löwik, Elsbeth Gautschi, George N. Thalmann, and Marco G. Cecchini

Optical Imaging of Cancer Metastasis to Bone Marrow : A Mouse Model of Minimal Residual Disease
Am J Pathol 2002 160: 1143-1153. [Abstract] [Full Text]  

Melpo Christofidou-Solomidou, Stephen Kennel, Arnaud Scherpereel, Rainer Wiewrodt, Charalambos C. Solomides, Giuseppe G. Pietra, Juan-Carlos Murciano, Sayed A. Shah, Harry Ischiropoulos, Steven M. Albelda, and Vladimir R. Muzykantov

Vascular Immunotargeting of Glucose Oxidase to the Endothelial Antigens Induces Distinct Forms of Oxidant Acute Lung Injury : Targeting to Thrombomodulin, But Not to PECAM-1, Causes Pulmonary Thrombosis and Neutrophil Transmigration
Am J Pathol 2002 160: 1155-1169. [Abstract] [Full Text]  

Ricardo V. Lloyd, Katharina H. Ruebel, Shuya Zhang, and Long Jin

Pituitary Hyperplasia in Glycoprotein Hormone Alpha Subunit-, p18^INK4C-, and p27^kip-1-Null Mice : Analysis of Proteins Influencing p27^kip-1 Ubiquitin Degradation
Am J Pathol 2002 160: 1171-1179. [Abstract] [Full Text]  

Liliana Schaefer, Katarina Macakova, Igor Raslik, Miroslava Micegova, Hermann-Josef Gröne, Elke Schönherr, Horst Robenek, Frank G. Echtermeyer, Susanne Grässel, Peter Bruckner, Roland M. Schaefer, Renato V. Iozzo, and Hans Kresse

Absence of Decorin Adversely Influences Tubulointerstitial Fibrosis of the Obstructed Kidney by Enhanced Apoptosis and Increased Inflammatory Reaction
Am J Pathol 2002 160: 1181-1191. [Abstract] [Full Text]  

Correction:

Correction
Am J Pathol 2002 160: 1193. [Full Text]  

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