Editorials:

Jay M. McDonald

A New Editor-in-Chief’s View Toward the Future
Am J Pathol 2003 163: 805. [Full Text]  

Reviews:

Hong D. Xiao, Sebastien Fuchs, Kristen Frenzel, Justin M. Cole, and Kenneth E. Bernstein

Newer Approaches to Genetic Modeling in Mice: Tissue-Specific Protein Expression as Studied Using Angiotensin-Converting Enzyme (ACE)
Am J Pathol 2003 163: 807-817. [Full Text]  

Short Communications:

Karin Hartmann, Metin Artuc, Stephan E. Baldus, Thomas K. Zirbes, Barbara Hermes, Juergen Thiele, Yoseph A. Mekori, and Beate M. Henz

Expression of Bcl-2 and Bcl-xL in Cutaneous and Bone Marrow Lesions of Mastocytosis
Am J Pathol 2003 163: 819-826. [Abstract] [Full Text]  

Susa Enholm, Tuija Hienonen, Anu Suomalainen, Lara Lipton, Ian Tomlinson, Vesa Kärjä, Matti Eskelinen, Jukka-Pekka Mecklin, Auli Karhu, Heikki J. Järvinen, and Lauri A. Aaltonen

Proportion and Phenotype of MYH-Associated Colorectal Neoplasia in a Population-Based Series of Finnish Colorectal Cancer Patients
Am J Pathol 2003 163: 827-832. [Abstract] [Full Text]  

Regular Articles:

Stefan Kins, Pascal Kurosinski, Roger M. Nitsch, and Jürgen Götz

Activation of the ERK and JNK Signaling Pathways Caused by Neuron-Specific Inhibition of PP2A in Transgenic Mice
Am J Pathol 2003 163: 833-843. [Abstract] [Full Text]  

Jin-Jing Pei, Cheng-Xin Gong, Wen-Lin An, Bengt Winblad, Richard F. Cowburn, Inge Grundke-Iqbal, and Khalid Iqbal

Okadaic-Acid-Induced Inhibition of Protein Phosphatase 2A Produces Activation of Mitogen-Activated Protein Kinases ERK1/2, MEK1/2, and p70 S6, Similar to That in Alzheimer’s Disease
Am J Pathol 2003 163: 845-858. [Abstract] [Full Text]  

Satoru Kyo, Kenkichi Masutomi, Yoshiko Maida, Taro Kanaya, Noriyuki Yatabe, Mitsuhiro Nakamura, Masaaki Tanaka, Mitsuko Takarada, Isamu Sugawara, Seishi Murakami, Takahiro Taira, and Masaki Inoue

Significance of Immunological Detection of Human Telomerase Reverse Transcriptase: Re-Evaluation of Expression and Localization of Human Telomerase Reverse Transcriptase
Am J Pathol 2003 163: 859-867. [Abstract] [Full Text]  

Nafiseh Nili, Asim N. Cheema, Frank J. Giordano, Alan W. Barolet, Saeid Babaei, Reed Hickey, Mohammad R. Eskandarian, Mirjam Smeets, Jagdish Butany, Gerard Pasterkamp, and Bradley H. Strauss

Decorin Inhibition of PDGF-Stimulated Vascular Smooth Muscle Cell Function: Potential Mechanism for Inhibition of Intimal Hyperplasia after Balloon Angioplasty
Am J Pathol 2003 163: 869-878. [Abstract] [Full Text]  

Stella Sarlos, Bishoy Rizkalla, Christina J. Moravski, Zemin Cao, Mark E. Cooper, and Jennifer L. Wilkinson-Berka

Retinal Angiogenesis Is Mediated by an Interaction between the Angiotensin Type 2 Receptor, VEGF, and Angiopoietin
Am J Pathol 2003 163: 879-887. [Abstract] [Full Text]  

Maria Pia Rastaldi, Silvia Armelloni, Silvia Berra, Min Li, Marzia Pesaresi, Helga Poczewski, Brigitte Langer, Dontscho Kerjaschki, Anna Henger, Simone Monika Blattner, Matthias Kretzler, Rudiger Wanke, and Giuseppe D’Amico

Glomerular Podocytes Possess the Synaptic Vesicle Molecule Rab3A and Its Specific Effector Rabphilin-3a
Am J Pathol 2003 163: 889-899. [Abstract] [Full Text]  

Bruno Stuhlmüller, Elke Kunisch, Juliane Franz, Lorena Martinez-Gamboa, Maria M. Hernandez, Axel Pruss, Norbert Ulbrich, Volker A. Erdmann, Gerd R. Burmester, and Raimund W. Kinne

Detection of Oncofetal H19 RNA in Rheumatoid Arthritis Synovial Tissue
Am J Pathol 2003 163: 901-911. [Abstract] [Full Text]  

Maria Debiec-Rychter, Romaric Croes, Rita De Vos, Peter Marynen, Tania Roskams, Anne Hagemeijer, Rita Lombaerts, and Raf Sciot

Complex Genomic Rearrangement of ALK Loci Associated with Integrated Human Epstein-Barr Virus in a Post-Transplant Myogenic Liver Tumor
Am J Pathol 2003 163: 913-922. [Abstract] [Full Text]  

Masashi Nakayama, Christina J. Bennett, Jessica L. Hicks, Jonathan I. Epstein, Elizabeth A. Platz, William G. Nelson, and Angelo M. De Marzo

Hypermethylation of the Human Glutathione S-Transferase- Gene (GSTP1) CpG Island Is Present in a Subset of Proliferative Inflammatory Atrophy Lesions but Not in Normal or Hyperplastic Epithelium of the Prostate: A Detailed Study Using Laser-Capture Microdissection
Am J Pathol 2003 163: 923-933. [Abstract] [Full Text]  

Edward M. Conway, Femke Zwerts, Veerle Van Eygen, Astrid DeVriese, Nobuo Nagai, Wei Luo, and Désiré Collen

Survivin-Dependent Angiogenesis in Ischemic Brain: Molecular Mechanisms of Hypoxia-Induced Up-Regulation
Am J Pathol 2003 163: 935-946. [Abstract] [Full Text]  

Stephan Seeliger, Thomas Vogl, Ingo Hubert Engels, J. Michael Schröder, Clemens Sorg, Cord Sunderkötter, and Johannes Roth

Expression of Calcium-Binding Proteins MRP8 and MRP14 in Inflammatory Muscle Diseases
Am J Pathol 2003 163: 947-956. [Abstract] [Full Text]  

Adriana Handra-Luca, Hadi Bilal, Jacques-Charles Bertrand, and Pierre Fouret

Extra-Cellular Signal-Regulated ERK-1/ERK-2 Pathway Activation in Human Salivary Gland Mucoepidermoid Carcinoma: Association to Aggressive Tumor Behavior and Tumor Cell Proliferation
Am J Pathol 2003 163: 957-967. [Abstract] [Full Text]  

Xiaowei Xu, Stephen Lyle, Yaping Liu, Benjamin Solky, and George Cotsarelis

Differential Expression of Cyclin D1 in the Human Hair Follicle
Am J Pathol 2003 163: 969-978. [Abstract] [Full Text]  

Bernard S. Buetow, Kristen A. Tappan, Jeffrey R. Crosby, Ronald A. Seifert, and Daniel F. Bowen-Pope

Chimera Analysis Supports a Predominant Role of PDGFRß in Promoting Smooth-Muscle Cell Chemotaxis after Arterial Injury
Am J Pathol 2003 163: 979-984. [Abstract] [Full Text]  

Peter Schraml, Georg Schwerdtfeger, Felix Burkhalter, Anna Raggi, Dietmar Schmidt, Teresa Ruffalo, Walter King, Kim Wilber, Michael J. Mihatsch, and Holger Moch

Combined Array Comparative Genomic Hybridization and Tissue Microarray Analysis Suggest PAK1 at 11q13.5-q14 as a Critical Oncogene Target in Ovarian Carcinoma
Am J Pathol 2003 163: 985-992. [Abstract] [Full Text]  

Zishan A. Haroon, Khalid Amin, Xiaohong Jiang, and Murat O. Arcasoy

A Novel Role for Erythropoietin During Fibrin-Induced Wound-Healing Response
Am J Pathol 2003 163: 993-1000. [Abstract] [Full Text]  

Oliver Stoeltzing, Wenbiao Liu, Niels Reinmuth, Fan Fan, Alexander A. Parikh, Corazon D. Bucana, Douglas B. Evans, Gregg L. Semenza, and Lee M. Ellis

Regulation of Hypoxia-Inducible Factor-1, Vascular Endothelial Growth Factor, and Angiogenesis by an Insulin-Like Growth Factor-I Receptor Autocrine Loop in Human Pancreatic Cancer
Am J Pathol 2003 163: 1001-1011. [Abstract] [Full Text]  

Peter Schraml, Alexander Hergovitz, Florian Hatz, Mahul B. Amin, So D. Lim, Wilhelm Krek, Michael J. Mihatsch, and Holger Moch

Relevance of Nuclear and Cytoplasmic von Hippel Lindau Protein Expression for Renal Carcinoma Progression
Am J Pathol 2003 163: 1013-1020. [Abstract] [Full Text]  

Takashi Horiguchi, Kunihiro Uryu, Benoit I. Giasson, Harry Ischiropoulos, Richard LightFoot, Christine Bellmann, Christiane Richter-Landsberg, Virginia M.-Y. Lee, and John Q. Trojanowski

Nitration of Tau Protein Is Linked to Neurodegeneration in Tauopathies
Am J Pathol 2003 163: 1021-1031. [Abstract] [Full Text]  

Jörg van den Boom, Marietta Wolter, Rork Kuick, David E. Misek, Andrew S. Youkilis, Daniel S. Wechsler, Clemens Sommer, Guido Reifenberger, and Samir M. Hanash

Characterization of Gene Expression Profiles Associated with Glioma Progression Using Oligonucleotide-Based Microarray Analysis and Real-Time Reverse Transcription-Polymerase Chain Reaction
Am J Pathol 2003 163: 1033-1043. [Abstract] [Full Text]  

Shaohua Li, Caroline Van Den Diepstraten, Sudhir J. D’Souza, Bosco M. C. Chan, and J. Geoffrey Pickering

Vascular Smooth Muscle Cells Orchestrate the Assembly of Type I Collagen via 2ß1 Integrin, RhoA, and Fibronectin Polymerization
Am J Pathol 2003 163: 1045-1056. [Abstract] [Full Text]  

Takashi Ishizawa, Narahiko Sahara, Koichi Ishiguro, Jay Kersh, Eileen McGowan, Jada Lewis, Michael Hutton, Dennis W. Dickson, and Shu-Hui Yen

Co-Localization of Glycogen Synthase Kinase-3 with Neurofibrillary Tangles and Granulovacuolar Degeneration in Transgenic Mice
Am J Pathol 2003 163: 1057-1067. [Abstract] [Full Text]  

Susanna H. Weerth, Horea Rus, Moon L. Shin, and Cedric S. Raine

Complement C5 in Experimental Autoimmune Encephalomyelitis (EAE) Facilitates Remyelination and Prevents Gliosis
Am J Pathol 2003 163: 1069-1080. [Abstract] [Full Text]  

Stefan Gattenlöhner, Christiane Waller, Georg Ertl, Burkhard-Dieter Bültmann, Hans-Konrad Müller-Hermelink, and Alexander Marx

NCAM(CD56) and RUNX1(AML1) Are Up-Regulated in Human Ischemic Cardiomyopathy and a Rat Model of Chronic Cardiac Ischemia
Am J Pathol 2003 163: 1081-1090. [Abstract] [Full Text]  

Andrew H. Fischer, Panya Taysavang, and Sissy M. Jhiang

Nuclear Envelope Irregularity Is Induced by RET/PTC During Interphase
Am J Pathol 2003 163: 1091-1100. [Abstract] [Full Text]  

Bin Yang, Mingzhou Guo, James G. Herman, and Douglas P. Clark

Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma
Am J Pathol 2003 163: 1101-1107. [Abstract] [Full Text]  

Akira Masuda, Ken Maeno, Taku Nakagawa, Hiroko Saito, and Takashi Takahashi

Association between Mitotic Spindle Checkpoint Impairment and Susceptibility to the Induction of Apoptosis by Anti-Microtubule Agents in Human Lung Cancers
Am J Pathol 2003 163: 1109-1116. [Abstract] [Full Text]  

Piers Davenport and Peter G. Tipping

The Role of Interleukin-4 and Interleukin-12 in the Progression of Atherosclerosis in Apolipoprotein E-Deficient Mice
Am J Pathol 2003 163: 1117-1125. [Abstract] [Full Text]  

Anja S. Mühlfeld, Stephan Segerer, Kelly Hudkins, Matthew D. Carling, Min Wen, Andrew G. Farr, Jeffrey V. Ravetch, and Charles E. Alpers

Deletion of the Fc Receptor IIb in Thymic Stromal Lymphopoietin Transgenic Mice Aggravates Membranoproliferative Glomerulonephritis
Am J Pathol 2003 163: 1127-1136. [Abstract] [Full Text]  

Zhanxiang Zhou, Lipeng Wang, Zhenyuan Song, Jason C. Lambert, Craig J. McClain, and Y. James Kang

A Critical Involvement of Oxidative Stress in Acute Alcohol-Induced Hepatic TNF- Production
Am J Pathol 2003 163: 1137-1146. [Abstract] [Full Text]  

Amy K. McNally and James M. Anderson

Foreign Body-Type Multinucleated Giant Cell Formation Is Potently Induced by -Tocopherol and Prevented by the Diacylglycerol Kinase Inhibitor R59022
Am J Pathol 2003 163: 1147-1156. [Abstract] [Full Text]  

Todd A. Wyatt, Mary A. Forgèt, and Joseph H. Sisson

Ethanol Stimulates Ciliary Beating by Dual Cyclic Nucleotide Kinase Activation in Bovine Bronchial Epithelial Cells
Am J Pathol 2003 163: 1157-1166. [Abstract] [Full Text]  

Yuan Li, Ting Zhang, Steven D. Douglas, Jian-Ping Lai, Wei-Dong Xiao, David E. Pleasure, and Wen-Zhe Ho

Morphine Enhances Hepatitis C Virus (HCV) Replicon Expression
Am J Pathol 2003 163: 1167-1175. [Abstract] [Full Text]  

Shereen Ezzat, Shunjiang Yu, and Sylvia L. Asa

Ikaros Isoforms in Human Pituitary Tumors: Distinct Localization, Histone Acetylation, and Activation of the 5' Fibroblast Growth Factor Receptor-4 Promoter
Am J Pathol 2003 163: 1177-1184. [Abstract] [Full Text]  

Christoph Daniel, Yoshitugu Takabatake, Masayuki Mizui, Yoshitaka Isaka, Hiroshi Kawashi, Harald Rupprecht, Enyu Imai, and Christian Hugo

Antisense Oligonucleotides Against Thrombospondin-1 Inhibit Activation of TGF-ß in Fibrotic Renal Disease in the Rat in Vivo
Am J Pathol 2003 163: 1185-1192. [Abstract] [Full Text]  

Jacob H. Rand, Xiao-Xuan Wu, Anthony S. Quinn, Pojen P. Chen, Keith R. McCrae, Edwin G. Bovill, and Douglas J. Taatjes

Human Monoclonal Antiphospholipid Antibodies Disrupt the Annexin A5 Anticoagulant Crystal Shield on Phospholipid Bilayers: Evidence from Atomic Force Microscopy and Functional Assay
Am J Pathol 2003 163: 1193-1200. [Abstract] [Full Text]  

Animal Models:

Manal Zabalawi, Shaila Bhat, Tara Loughlin, Michael J. Thomas, Eric Alexander, Mark Cline, Bill Bullock, Mark Willingham, and Mary G. Sorci-Thomas

Induction of Fatal Inflammation in LDL Receptor and ApoA-I Double-Knockout Mice Fed Dietary Fat and Cholesterol
Am J Pathol 2003 163: 1201-1213. [Abstract] [Full Text]  

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