Reviews:

James W. Mandell

Phosphorylation State-Specific Antibodies: Applications in Investigative and Diagnostic Pathology
Am J Pathol 2003 163: 1687-1698. [Abstract] [Full Text]  

Commentaries:

Stephen W. Chensue

Exposing a Killer: Pathologists Angle for Anthrax
Am J Pathol 2003 163: 1699-1702. [Full Text]  

Andrew P. Mizisin

Comparative Neuropathology and Diabetic Autonomic Neuropathy
Am J Pathol 2003 163: 1703-1706. [Full Text]  

Short Communications:

Shigeki Sekine, Sunao Sato, Takashi Takata, Yasuo Fukuda, Takeshi Ishida, Mitsunobu Kishino, Tatsuhiro Shibata, Yae Kanai, and Setsuo Hirohashi

ß-Catenin Mutations Are Frequent in Calcifying Odontogenic Cysts, but Rare in Ameloblastomas
Am J Pathol 2003 163: 1707-1712. [Abstract] [Full Text]  

Maddalena T. Tilli, M. Silvina Frech, Mary E. Steed, Kathleen S. Hruska, Michael D. Johnson, Jodi A. Flaws, and Priscilla A. Furth

Introduction of Estrogen Receptor- into the tTA/TAg Conditional Mouse Model Precipitates the Development of Estrogen-Responsive Mammary Adenocarcinoma
Am J Pathol 2003 163: 1713-1719. [Abstract] [Full Text]  

Andrey Korshunov, Kai Neben, Gunnar Wrobel, Bjoern Tews, Axel Benner, Meinhard Hahn, Andrey Golanov, and Peter Lichter

Gene Expression Patterns in Ependymomas Correlate with Tumor Location, Grade, and Patient Age
Am J Pathol 2003 163: 1721-1727. [Abstract] [Full Text]  

Fumio Ide, Munenori Kitada, Hideaki Sakashita, Kaoru Kusama, Kiyoji Tanaka, and Takatoshi Ishikawa

p53 Haploinsufficiency Profoundly Accelerates the Onset of Tongue Tumors in Mice Lacking the Xeroderma Pigmentosum Group A Gene
Am J Pathol 2003 163: 1729-1733. [Abstract] [Full Text]  

Ryan D. McAllister, Yogendra Singh, Wendy D. du Bois, Michael Potter, Thomas Boehm, Nathan D. Meeker, Parley D. Fillmore, Lisa M. Anderson, Matthew E. Poynter, and Cory Teuscher

Susceptibility to Anthrax Lethal Toxin Is Controlled by Three Linked Quantitative Trait Loci
Am J Pathol 2003 163: 1735-1741. [Abstract] [Full Text]  

Technical Advances:

Jop Perrée, Ton G. van Leeuwen, Raphaella Kerindongo, Jos A. E. Spaan, and Ed VanBavel

Function and Structure of Pressurized and Perfused Porcine Carotid Arteries: Effects of in Vitro Balloon Angioplasty
Am J Pathol 2003 163: 1743-1750. [Abstract] [Full Text]  

Sven Perner, Silke Brüderlein, Cornelia Hasel, Irena Waibel, Alexandra Holdenried, Neslisah Ciloglu, Heiko Chopurian, Kirsten Vang Nielsen, Andreas Plesch, Josef Högel, and Peter Möller

Quantifying Telomere Lengths of Human Individual Chromosome Arms by Centromere-Calibrated Fluorescence in Situ Hybridization and Digital Imaging
Am J Pathol 2003 163: 1751-1756. [Abstract] [Full Text]  

Regular Articles:

Theresa P. Pretlow, Winfried Edelmann, Raju Kucherlapati, Thomas G. Pretlow, and Leonard H. Augenlicht

Spontaneous Aberrant Crypt Foci in Apc1638N Mice with a Mutant Apc Allele
Am J Pathol 2003 163: 1757-1763. [Abstract] [Full Text]  

Boris C. Bastian, Adam B. Olshen, Philip E. LeBoit, and Daniel Pinkel

Classifying Melanocytic Tumors Based on DNA Copy Number Changes
Am J Pathol 2003 163: 1765-1770. [Abstract] [Full Text]  

Abdoelwaheb El Ghalbzouri, Marcel Jonkman, Johanna Kempenaar, and Maria Ponec

Recessive Epidermolysis Bullosa Simplex Phenotype Reproduced in Vitro: Ablation of Keratin 14 Is Partially Compensated by Keratin 17
Am J Pathol 2003 163: 1771-1779. [Abstract] [Full Text]  

Janardhan Sampath, Pandy R. Long, Robert L. Shepard, Xiaoling Xia, Viswanath Devanarayan, George E. Sandusky, William L. Perry, III, Anne H. Dantzig, Mark Williamson, Mark Rolfe, and Robert E. Moore

Human SPF45, a Splicing Factor, Has Limited Expression in Normal Tissues, Is Overexpressed in Many Tumors, and Can Confer a Multidrug-Resistant Phenotype to Cells
Am J Pathol 2003 163: 1781-1790. [Abstract] [Full Text]  

Dominique Joly, Viviane Morel, Aurélie Hummel, Antonella Ruello, Patrick Nusbaum, Natacha Patey, Laure-Hélène Noël, Patricia Rousselle, and Bertrand Knebelmann

ß₄ Integrin and Laminin 5 Are Aberrantly Expressed in Polycystic Kidney Disease: Role in Increased Cell Adhesion and Migration
Am J Pathol 2003 163: 1791-1800. [Abstract] [Full Text]  

Peter Baluk, Shunichi Morikawa, Amy Haskell, Michael Mancuso, and Donald M. McDonald

Abnormalities of Basement Membrane on Blood Vessels and Endothelial Sprouts in Tumors
Am J Pathol 2003 163: 1801-1815. [Abstract] [Full Text]  

Masatoshi Deguchi, Diana Whitaker-Menezes, Stephen C. Jones, Setsuya Aiba, Satoshi Nakagawa, Hachiro Tagami, Robert Korngold, and George F. Murphy

12E2: A Cloned Murine Dermal Cell with Features of Dermal Dendrocytes and Capacity to Produce Pathologic Changes Resembling Early Kaposi’s Sarcoma
Am J Pathol 2003 163: 1817-1825. [Abstract] [Full Text]  

Kutty Selva Nandakumar, Lars Svensson, and Rikard Holmdahl

Collagen Type II-Specific Monoclonal Antibody-Induced Arthritis in Mice: Description of the Disease and the Influence of Age, Sex, and Genes
Am J Pathol 2003 163: 1827-1837. [Abstract] [Full Text]  

Peter van Lent, Karin C. Nabbe, Peter Boross, Arjen B. Blom, Johannes Roth, Astrid Holthuysen, Annet Sloetjes, Sjef Verbeek, and Wim van den Berg

The Inhibitory Receptor FcRII Reduces Joint Inflammation and Destruction in Experimental Immune Complex-Mediated Arthritides Not Only by Inhibition of FcRI/III but Also by Efficient Clearance and Endocytosis of Immune Complexes
Am J Pathol 2003 163: 1839-1848. [Abstract] [Full Text]  

Fiona Oakley, Nathan Trim, Christothea M. Constandinou, Weilan Ye, Alane M. Gray, Gretchen Frantz, Kenneth Hillan, Tim Kendall, R. Christopher Benyon, Derek A. Mann, and John P. Iredale

Hepatocytes Express Nerve Growth Factor during Liver Injury: Evidence for Paracrine Regulation of Hepatic Stellate Cell Apoptosis
Am J Pathol 2003 163: 1849-1858. [Abstract] [Full Text]  

Cheng Liu, Gourab Bhattacharjee, William Boisvert, Ralph Dilley, and Thomas Edgington

In Vivo Interrogation of the Molecular Display of Atherosclerotic Lesion Surfaces
Am J Pathol 2003 163: 1859-1871. [Abstract] [Full Text]  

Charles Heilig, Frank Brosius, Brian Siu, Luis Concepcion, Richard Mortensen, Kathleen Heilig, Min Zhu, Richard Weldon, Guimei Wu, and David Conner

Implications of Glucose Transporter Protein Type 1 (GLUT1)-Haplodeficiency in Embryonic Stem Cells for Their Survival in Response to Hypoxic Stress
Am J Pathol 2003 163: 1873-1885. [Abstract] [Full Text]  

Birgitte Vrou Offersen, Boye Schnack Nielsen, Gunilla Høyer-Hansen, Fritz Rank, Stephen Hamilton-Dutoit, Jens Overgaard, and Peter A. Andreasen

The Myofibroblast Is the Predominant Plasminogen Activator Inhibitor-1-Expressing Cell Type in Human Breast Carcinomas
Am J Pathol 2003 163: 1887-1899. [Abstract] [Full Text]  

Wun-Ju Shieh, Jeannette Guarner, Christopher Paddock, Patricia Greer, Kathleen Tatti, Marc Fischer, Marci Layton, Michael Philips, Eddy Bresnitz, Conrad P. Quinn, Tanja Popovic, Bradley A. Perkins, and Sherif R. Zaki

The Critical Role of Pathology in the Investigation of Bioterrorism-Related Cutaneous Anthrax
Am J Pathol 2003 163: 1901-1910. [Abstract] [Full Text]  

Yuji Akiyama, Chihaya Maesawa, Satoshi Ogasawara, Masanori Terashima, and Tomoyuki Masuda

Cell-Type-Specific Repression of the Maspin Gene Is Disrupted Frequently by Demethylation at the Promoter Region in Gastric Intestinal Metaplasia and Cancer Cells
Am J Pathol 2003 163: 1911-1919. [Abstract] [Full Text]  

Camilla Göktürk, Joakim Nilsson, Jenny Nordquist, Millvej Kristensson, Kristian Svensson, Charlotte Söderberg, Marianne Israelson, Håkan Garpenstrand, Mats Sjöquist, Lars Oreland, and Karin Forsberg-Nilsson

Overexpression of Semicarbazide-Sensitive Amine Oxidase in Smooth Muscle Cells Leads to an Abnormal Structure of the Aortic Elastic Laminas
Am J Pathol 2003 163: 1921-1928. [Abstract] [Full Text]  

Marina Fanin, Anna Chiara Nascimbeni, Luigi Fulizio, Carlo Pietro Trevisan, Marija Meznaric-Petrusa, and Corrado Angelini

Loss of Calpain-3 Autocatalytic Activity in LGMD2A Patients with Normal Protein Expression
Am J Pathol 2003 163: 1929-1936. [Abstract] [Full Text]  

Monica Rupérez, Marta Ruiz-Ortega, Vanesa Esteban, Óscar Lorenzo, Sergio Mezzano, Juan Jose Plaza, and Jesús Egido

Angiotensin II Increases Connective Tissue Growth Factor in the Kidney
Am J Pathol 2003 163: 1937-1947. [Abstract] [Full Text]  

Alain C. Borczuk, Lyall Gorenstein, Kristin L. Walter, Adel A. Assaad, Liqun Wang, and Charles A. Powell

Non-Small-Cell Lung Cancer Molecular Signatures Recapitulate Lung Developmental Pathways
Am J Pathol 2003 163: 1949-1960. [Abstract] [Full Text] Data Supplement to Am J Pathol 2003, 163:1949-1960  

Steven K. Lundy, Aaron A. Berlin, and Nicholas W. Lukacs

Interleukin-12-Independent Down-Modulation of Cockroach Antigen-Induced Asthma in Mice by Intranasal Exposure to Bacterial Lipopolysaccharide
Am J Pathol 2003 163: 1961-1968. [Abstract] [Full Text]  

Marion Buyse, Laetitia Charrier, Shanthi Sitaraman, Andrew Gewirtz, and Didier Merlin

Interferon- Increases hPepT1-Mediated Uptake of Di-Tripeptides Including the Bacterial Tripeptide fMLP in Polarized Intestinal Epithelia
Am J Pathol 2003 163: 1969-1977. [Abstract] [Full Text]  

Päivikki Kauraniemi, Tuula Kuukasjärvi, Guido Sauter, and Anne Kallioniemi

Amplification of a 280-Kilobase Core Region at the ERBB2 Locus Leads to Activation of Two Hypothetical Proteins in Breast Cancer
Am J Pathol 2003 163: 1979-1984. [Abstract] [Full Text]  

Kerby A. Shedden, Jeremy M. G. Taylor, Thomas J. Giordano, Rork Kuick, David E. Misek, Gad Rennert, Donald R. Schwartz, Stephen B. Gruber, Craig Logsdon, Diane Simeone, Sharon L. R. Kardia, Joel K. Greenson, Kathleen R. Cho, David G. Beer, Eric R. Fearon, and Samir Hanash

Accurate Molecular Classification of Human Cancers Based on Gene Expression Using a Simple Classifier with a Pathological Tree-Based Framework
Am J Pathol 2003 163: 1985-1995. [Abstract] [Full Text]  

Azza B. El-Remessy, Ibrahim E. Khalil, Suraporn Matragoon, Gamal Abou-Mohamed, Nai-Jer Tsai, Penny Roon, Ruth B. Caldwell, Robert W. Caldwell, Keith Green, and Gregory I. Liou

Neuroprotective Effect of(-)⁹-Tetrahydrocannabinol and Cannabidiol in N-Methyl-D-Aspartate-Induced Retinal Neurotoxicity: Involvement of Peroxynitrite
Am J Pathol 2003 163: 1997-2008. [Abstract] [Full Text]  

Siew-Kian Tai, Owen June-Keong Tan, Vincent Tak-Kwong Chow, Rongxian Jin, J. Louise Jones, Puay-Hoon Tan, Anita Jayasurya, and Boon-Huat Bay

Differential Expression of Metallothionein 1 and 2 Isoforms in Breast Cancer Lines with Different Invasive Potential: Identification of a Novel Nonsilent Metallothionein-1H Mutant Variant
Am J Pathol 2003 163: 2009-2019. [Abstract] [Full Text]  

Eva Grimaud, Luc Soubigou, Séverine Couillaud, Patrick Coipeau, Anne Moreau, Norbert Passuti, François Gouin, Françoise Redini, and Dominique Heymann

Receptor Activator of Nuclear Factor B Ligand (RANKL)/Osteoprotegerin (OPG) Ratio Is Increased in Severe Osteolysis
Am J Pathol 2003 163: 2021-2031. [Abstract] [Full Text]  

Andrew Wallace McGowan Minto, Lars-Peter Erwig, and Andrew Jackson Rees

Heterogeneity of Macrophage Activation in Anti-Thy-1.1 Nephritis
Am J Pathol 2003 163: 2033-2041. [Abstract] [Full Text]  

Julie T. Daniels, Gregory S. Schultz, Timothy D. Blalock, Qian Garrett, Gary R. Grotendorst, Nicholas M. Dean, and Peng T. Khaw

Mediation of Transforming Growth Factor-ß₁-Stimulated Matrix Contraction by Fibroblasts: A Role for Connective Tissue Growth Factor in Contractile Scarring
Am J Pathol 2003 163: 2043-2052. [Abstract] [Full Text]  

Eun-Young Ahn, George Pan, Jae Hwan Oh, Ewan M. Tytler, and Jay M. McDonald

The Combination of Calmodulin Antagonists and Interferon- Induces Apoptosis through Caspase-Dependent and -Independent Pathways in Cholangiocarcinoma Cells
Am J Pathol 2003 163: 2053-2063. [Abstract] [Full Text]  

Sofie Struyf, Evemie Schutyser, Mieke Gouwy, Klara Gijsbers, Paul Proost, Yves Benoit, Ghislain Opdenakker, Jo Van Damme, and Geneviève Laureys

PARC/CCL18 Is a Plasma CC Chemokine with Increased Levels in Childhood Acute Lymphoblastic Leukemia
Am J Pathol 2003 163: 2065-2075. [Abstract] [Full Text]  

Animal Models:

Robert E. Schmidt, Denise A. Dorsey, Lucie N. Beaudet, Kathy E. Frederick, Curtis A. Parvin, Santiago B. Plurad, and Matteo G. Levisetti

Non-Obese Diabetic Mice Rapidly Develop Dramatic Sympathetic Neuritic Dystrophy: A New Experimental Model of Diabetic Autonomic Neuropathy
Am J Pathol 2003 163: 2077-2091. [Abstract] [Full Text]  

You-Hai Xu, Brian Quinn, David Witte, and Gregory A. Grabowski

Viable Mouse Models of Acid ß-Glucosidase Deficiency: The Defect in Gaucher Disease
Am J Pathol 2003 163: 2093-2101. [Abstract] [Full Text]  

Michal A. Elovitz, Zhao Wang, Edward K. Chien, Daniel F. Rychlik, and Mark Phillippe

A New Model for Inflammation-Induced Preterm Birth: The Role of Platelet-Activating Factor and Toll-Like Receptor-4
Am J Pathol 2003 163: 2103-2111. [Abstract] [Full Text]  

Elaine Y. Lin, Joan G. Jones, Ping Li, Liyin Zhu, Kathleen D. Whitney, William J. Muller, and Jeffrey W. Pollard

Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases
Am J Pathol 2003 163: 2113-2126. [Abstract] [Full Text]  

K. Thong Wong, Isabelle Grosjean, Christine Brisson, Barissa Blanquier, Michelle Fevre-Montange, Arlette Bernard, Philippe Loth, Marie-Claude Georges-Courbot, Michelle Chevallier, Hideo Akaoka, Philippe Marianneau, Sai Kit Lam, T. Fabian Wild, and Vincent Deubel

A Golden Hamster Model for Human Acute Nipah Virus Infection
Am J Pathol 2003 163: 2127-2137. [Abstract] [Full Text]  

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