Review Article: Manon J. Winter, Iris D. Nagtegaal, J. Han J. M. van Krieken, and Sergey V. Litvinov The Epithelial Cell Adhesion Molecule (Ep-CAM) as a Morphoregulatory Molecule Is a Tool in Surgical Pathology Am J Pathol 2003 163: 2139-2148. [Abstract] [Full Text] [PDF]

Short Communications: Rolf I. Skotheim, Kemal S. Korkmaz, Tove I. Klokk, Vera M. Abeler, Ceren G. Korkmaz, Jahn M. Nesland, Sophie D. Fosså, Ragnhild A. Lothe, and Fahri Saatcioglu NKX3.1 Expression Is Lost in Testicular Germ Cell Tumors Am J Pathol 2003 163: 2149-2154. [Abstract] [Full Text] [PDF]   Ling Li, Dongfeng Cao, David W. Garber, Helen Kim, and Ken-ichiro Fukuchi Association of Aortic Atherosclerosis with Cerebral ß-Amyloidosis and Learning Deficits in a Mouse Model of Alzheimer’s Disease Am J Pathol 2003 163: 2155-2164. [Abstract] [Full Text] [PDF]   Emi Ito, Reiko Honma, Jun-ichi Imai, Sakura Azuma, Takayuki Kanno, Shigeo Mori, Osamu Yoshie, Jun Nishio, Hiroshi Iwasaki, Koichi Yoshida, Jin Gohda, Jun-ichiro Inoue, Shinya Watanabe, and Kentaro Semba A Tetraspanin-Family Protein, T-Cell Acute Lymphoblastic Leukemia-Associated Antigen 1, Is Induced by the Ewing’s Sarcoma-Wilms’ Tumor 1 Fusion Protein of Desmoplastic Small Round-Cell Tumor Am J Pathol 2003 163: 2165-2172. [Abstract] [Full Text] [PDF]   Mary Allen, Marina Grachtchouk, Hong Sheng, Vladimir Grachtchouk, Anna Wang, Lebing Wei, Jianhong Liu, Angel Ramirez, Daniel Metzger, Pierre Chambon, Jose Jorcano, and Andrzej A. Dlugosz Hedgehog Signaling Regulates Sebaceous Gland Development Am J Pathol 2003 163: 2173-2178. [Abstract] [Full Text] [PDF]   Diethilde Theil, Tobias Derfuss, Igor Paripovic, Simone Herberger, Edgar Meinl, Olaf Schueler, Michael Strupp, Viktor Arbusow, and Thomas Brandt Latent Herpesvirus Infection in Human Trigeminal Ganglia Causes Chronic Immune Response Am J Pathol 2003 163: 2179-2184. [Abstract] [Full Text] [PDF]   Wei Li, Carol H. Thompson, Ding Xin, Yvonne E. Cossart, Christopher J. O’Brien, Edward B. McNeil, Kan Gao, Richard A. Scolyer, and Barbara R. Rose Absence of Human Papillomavirus in Tonsillar Squamous Cell Carcinomas from Chinese Patients Am J Pathol 2003 163: 2185-2189. [Abstract] [Full Text] [PDF]

Technical Advances: Cécile Michel, Chantal Desdouets, Béatrice Sacre-Salem, Jean-Charles Gautier, Ruth Roberts, and Eric Boitier Liver Gene Expression Profiles of Rats Treated with Clofibric Acid: Comparison of Whole Liver and Laser Capture Microdissected Liver Am J Pathol 2003 163: 2191-2199. [Abstract] [Full Text] [PDF]   Hidehisa Yamada, Keiji Furuuchi, Tetsuya Aoyama, Akihiko Kataoka, Jun-ichi Hamada, Mitsuhiro Tada, Shunichi Okushiba, Satoshi Kondo, Tetsuya Moriuchi, and Hiroyuki Katoh Reconstructed ß-Catenin/TCF4 Signaling in Yeast Applicable to Functional Evaluation of APC Mutations Am J Pathol 2003 163: 2201-2209. [Abstract] [Full Text] [PDF]

Regular Articles: Jun Nakayama, Daisuke Aoki, Tomoaki Suga, Tomoya O. Akama, Satoshi Ishizone, Hirohito Yamaguchi, Kazuhiko Imakawa, Daita Nadano, Asgerally T. Fazleabas, Tsutomu Katsuyama, Shiro Nozawa, and Michiko N. Fukuda Implantation-Dependent Expression of Trophinin by Maternal Fallopian Tube Epithelia during Tubal Pregnancies: Possible Role of Human Chorionic Gonadotrophin on Ectopic Pregnancy Am J Pathol 2003 163: 2211-2219. [Abstract] [Full Text] [PDF]   Hiroshi Tazawa, Futoshi Okada, Tokushige Kobayashi, Mitsuhiro Tada, Yukiko Mori, Yoshie Une, Fujiro Sendo, Masanobu Kobayashi, and Masuo Hosokawa Infiltration of Neutrophils Is Required for Acquisition of Metastatic Phenotype of Benign Murine Fibrosarcoma Cells: Implication of Inflammation-Associated Carcinogenesis and Tumor Progression Am J Pathol 2003 163: 2221-2232. [Abstract] [Full Text] [PDF]   Alanna Ruddell, Pau Mezquita, Kimberly A. Brandvold, Andrew Farr, and Brian M. Iritani B Lymphocyte-Specific c-Myc Expression Stimulates Early and Functional Expansion of the Vasculature and Lymphatics during Lymphomagenesis Am J Pathol 2003 163: 2233-2245. [Abstract] [Full Text] [PDF]   Kathleen C. Flanders, Christopher D. Major, Alidad Arabshahi, Ekinadese E. Aburime, Miya H. Okada, Makiko Fujii, Timothy D. Blalock, Gregory S. Schultz, Anastasia Sowers, Mario A. Anzano, James B. Mitchell, Angelo Russo, and Anita B. Roberts Interference with Transforming Growth Factor-ß/ Smad3 Signaling Results in Accelerated Healing of Wounds in Previously Irradiated Skin Am J Pathol 2003 163: 2247-2257. [Abstract] [Full Text] [PDF]   Satoru Kyo, Mitsuhiro Nakamura, Tohru Kiyono, Yoshiko Maida, Taro Kanaya, Masaaki Tanaka, Noriyuki Yatabe, and Masaki Inoue Successful Immortalization of Endometrial Glandular Cells with Normal Structural and Functional Characteristics Am J Pathol 2003 163: 2259-2269. [Abstract] [Full Text] [PDF]   Guangyuan Zeng, Zhiqiang Hu, Michael S. Kinch, Chong-Xian Pan, David A. Flockhart, Chinghai Kao, Thomas A. Gardner, Shaobo Zhang, Lang Li, Lee Ann Baldridge, Michael O. Koch, Thomas M. Ulbright, John N. Eble, and Liang Cheng High-Level Expression of EphA2 Receptor Tyrosine Kinase in Prostatic Intraepithelial Neoplasia Am J Pathol 2003 163: 2271-2276. [Abstract] [Full Text] [PDF]   Claudio Doglioni, Sara Piccinin, Silvia Demontis, Maria Giulia Cangi, Lorenza Pecciarini, Concetta Chiarelli, Michela Armellin, Tamara Vukosavljevic, Mauro Boiocchi, and Roberta Maestro Alterations of ß-Catenin Pathway in Non-Melanoma Skin Tumors: Loss of -ABC Nuclear Reactivity Correlates with the Presence of ß-Catenin Gene Mutation Am J Pathol 2003 163: 2277-2287. [Abstract] [Full Text] [PDF]   Hai-Tao Yuan, Xiao-Zhong Li, Jolanta E. Pitera, David A. Long, and Adrian S. Woolf Peritubular Capillary Loss after Mouse Acute Nephrotoxicity Correlates with Down-Regulation of Vascular Endothelial Growth Factor-A and Hypoxia-Inducible Factor-1 Am J Pathol 2003 163: 2289-2301. [Abstract] [Full Text] [PDF]   Devanshi Seth, Maria A. Leo, Peter H. McGuinness, Charles S. Lieber, Yvonne Brennan, Rohan Williams, Xin M. Wang, Geoffrey W. McCaughan, Mark D. Gorrell, and Paul S. Haber Gene Expression Profiling of Alcoholic Liver Disease in the Baboon (Papio hamadryas) and Human Liver Am J Pathol 2003 163: 2303-2317. [Abstract] [Full Text] [PDF]   Cecilia L. Speyer, Thomas A. Neff, Roscoe L. Warner, Ren-Feng Guo, J. Vidya Sarma, Niels C. Riedemann, Megan E. Murphy, Hedwig S. Murphy, and Peter A. Ward Regulatory Effects of iNOS on Acute Lung Inflammatory Responses in Mice Am J Pathol 2003 163: 2319-2328. [Abstract] [Full Text] [PDF]   Steven D. Shapiro, Nir M. Goldstein, A. McGarry Houghton, Dale K. Kobayashi, Diane Kelley, and Abderazzaq Belaaouaj Neutrophil Elastase Contributes to Cigarette Smoke-Induced Emphysema in Mice Am J Pathol 2003 163: 2329-2335. [Abstract] [Full Text] [PDF]   Jamshid Khoshnoodi, Kristmundur Sigmundsson, Lars-Göran Öfverstedt, Ulf Skoglund, Björn Öbrink, Jorma Wartiovaara, and Karl Tryggvason Nephrin Promotes Cell-Cell Adhesion through Homophilic Interactions Am J Pathol 2003 163: 2337-2346. [Abstract] [Full Text] [PDF]   Thomas W. Geisbert, Lisa E. Hensley, Tom Larsen, Howard A. Young, Douglas S. Reed, Joan B. Geisbert, Dana P. Scott, Elliott Kagan, Peter B. Jahrling, and Kelly J. Davis Pathogenesis of Ebola Hemorrhagic Fever in Cynomolgus Macaques: Evidence that Dendritic Cells Are Early and Sustained Targets of Infection Am J Pathol 2003 163: 2347-2370. [Abstract] [Full Text] [PDF]   Thomas W. Geisbert, Howard A. Young, Peter B. Jahrling, Kelly J. Davis, Tom Larsen, Elliott Kagan, and Lisa E. Hensley Pathogenesis of Ebola Hemorrhagic Fever in Primate Models: Evidence that Hemorrhage Is Not a Direct Effect of Virus-Induced Cytolysis of Endothelial Cells Am J Pathol 2003 163: 2371-2382. [Abstract] [Full Text] [PDF]   Sabine C. Linn, Rob B. West, Jonathan R. Pollack, Shirley Zhu, Tina Hernandez-Boussard, Torsten O. Nielsen, Brian P. Rubin, Rajiv Patel, John R. Goldblum, David Siegmund, David Botstein, Patrick O. Brown, C. Blake Gilks, and Matt van de Rijn Gene Expression Patterns and Gene Copy Number Changes in Dermatofibrosarcoma Protuberans Am J Pathol 2003 163: 2383-2395. [Abstract] [Full Text] [PDF]   Robert Paine, III, Steven E. Wilcoxen, Susan B. Morris, Claudio Sartori, Carlos E. O. Baleeiro, Michael A. Matthay, and Paul J. Christensen Transgenic Overexpression of Granulocyte Macrophage-Colony Stimulating Factor in the Lung Prevents Hyperoxic Lung Injury Am J Pathol 2003 163: 2397-2406. [Abstract] [Full Text] [PDF]   Yanwen Li, Zhigang Pan, Yuan Ji, Mary Sheppard, Donald J. Jeffries, Leonard C. Archard, and Hongyi Zhang Herpes Simplex Virus Type 1 Infection Associated with Atrial Myxoma Am J Pathol 2003 163: 2407-2412. [Abstract] [Full Text] [PDF]   Nir Grabie, Dennis T. Hsieh, Chiara Buono, Jason R. Westrich, Jessica A. Allen, Hong Pang, George Stavrakis, and Andrew H. Lichtman Neutrophils Sustain Pathogenic CD8+ T Cell Responses in the Heart Am J Pathol 2003 163: 2413-2420. [Abstract] [Full Text] [PDF]   Scott L. Hansen, Connie A. Myers, Aubri Charboneau, David M. Young, and Nancy Boudreau HoxD3 Accelerates Wound Healing in Diabetic Mice Am J Pathol 2003 163: 2421-2431. [Abstract] [Full Text] [PDF]   Jitka Ismail Virag and Charles E. Murry Myofibroblast and Endothelial Cell Proliferation during Murine Myocardial Infarct Repair Am J Pathol 2003 163: 2433-2440. [Abstract] [Full Text] [PDF] [Supplemental Data]   Hui-Ching Wang, Han-Chieh Wu, Chien-Fu Chen, Nelson Fausto, Huan-Yao Lei, and Ih-Jen Su Different Types of Ground Glass Hepatocytes in Chronic Hepatitis B Virus Infection Contain Specific Pre-S Mutants that May Induce Endoplasmic Reticulum Stress Am J Pathol 2003 163: 2441-2449. [Abstract] [Full Text] [PDF]   Steven D. Billings, Michael D. Southall, Tao Li, Paul W. Cook, LeeAnn Baldridge, William B. Moores, Daniel F. Spandau, John G. Foley, and Jeffrey B. Travers Amphiregulin Overexpression Results in Rapidly Growing Keratinocytic Tumors: An In Vivo Xenograft Model of Keratoacanthoma Am J Pathol 2003 163: 2451-2458. [Abstract] [Full Text] [PDF]   Chia Soo, Steven R. Beanes, Fei-Ya Hu, Xinli Zhang, Catherine Dang, Grace Chang, Yubert Wang, Ichiro Nishimura, Earl Freymiller, Michael T. Longaker, H.Peter Lorenz, and Kang Ting Ontogenetic Transition in Fetal Wound Transforming Growth Factor-ß Regulation Correlates with Collagen Organization Am J Pathol 2003 163: 2459-2476. [Abstract] [Full Text] [PDF]   Kevin M. Kernek, Thomas M. Ulbright, Shaobo Zhang, Steven D. Billings, Oscar W. Cummings, John D. Henley, Helen Michael, Matteo Brunelli, Guido Martignoni, Richard S. Foster, John N. Eble, and Liang Cheng Identical Allelic Losses in Mature Teratoma and Other Histologic Components of Malignant Mixed Germ Cell Tumors of the Testis Am J Pathol 2003 163: 2477-2484. [Abstract] [Full Text] [PDF]   Gwenaële Garin, Chérif Badid, Brigitte McGregor, Madeleine Vincent, Sylviane Guerret, Kazem Zibara, Adam Hurlstone, Maurice Laville, and John L. McGregor Ischemia Induces Early Expression of a New Transcription Factor (6A3-5) in Kidney Vascular Smooth Muscle Cells: Studies in Rat and Human Renal Pathology Am J Pathol 2003 163: 2485-2494. [Abstract] [Full Text] [PDF]   Liang Shan, Minshu Yu, Cunping Qiu, and Elizabeth G. Snyderwine Id4 Regulates Mammary Epithelial Cell Growth and Differentiation and Is Overexpressed in Rat Mammary Gland Carcinomas Am J Pathol 2003 163: 2495-2502. [Abstract] [Full Text] [PDF]   Akira Tsuchiya, Michiie Sakamoto, Jun Yasuda, Makoto Chuma, Tsutomu Ohta, Misao Ohki, Toshiharu Yasugi, Yuji Taketani, and Setsuo Hirohashi Expression Profiling in Ovarian Clear Cell Carcinoma: Identification of Hepatocyte Nuclear Factor-1ß as a Molecular Marker and a Possible Molecular Target for Therapy of Ovarian Clear Cell Carcinoma Am J Pathol 2003 163: 2503-2512. [Abstract] [Full Text] [PDF]   Neville N. C. Tam, Ying Gao, Yuet-Kin Leung, and Shuk-Mei Ho Androgenic Regulation of Oxidative Stress in the Rat Prostate: Involvement of NAD(P)H Oxidases and Antioxidant Defense Machinery during Prostatic Involution and Regrowth Am J Pathol 2003 163: 2513-2522. [Abstract] [Full Text] [PDF]   Xiaopeng Li, Heather Rayford, and Bruce D. Uhal Essential Roles for Angiotensin Receptor AT1a in Bleomycin-Induced Apoptosis and Lung Fibrosis in Mice Am J Pathol 2003 163: 2523-2530. [Abstract] [Full Text] [PDF]   Suresh Kumar, Hiromitsu Kishimoto, Hui Lin Chua, Sunil Badve, Kathy D. Miller, Robert M. Bigsby, and Harikrishna Nakshatri Interleukin-1 Promotes Tumor Growth and Cachexia in MCF-7 Xenograft Model of Breast Cancer Am J Pathol 2003 163: 2531-2541. [Abstract] [Full Text] [PDF]   Mariarosaria Lovecchio, Eugenio Maiorano, Rosa A. Vacca, Giuseppe Loverro, Margherita Fanelli, Leonardo Resta, Sergio Stefanelli, Luigi Selvaggi, Ersilia Marra, and Elda Perlino ß1C Integrin Expression in Human Endometrial Proliferative Diseases Am J Pathol 2003 163: 2543-2553. [Abstract] [Full Text] [PDF]   Leo E. Otterbein, Sherrie L. Otterbein, Emeka Ifedigbo, Fang Liu, Danielle E. Morse, Colleen Fearns, Richard J. Ulevitch, Roy Knickelbein, Richard A. Flavell, and Augustine M. Choi MKK3 Mitogen-Activated Protein Kinase Pathway Mediates Carbon Monoxide-Induced Protection Against Oxidant-Induced Lung Injury Am J Pathol 2003 163: 2555-2563. [Abstract] [Full Text] [PDF]   Donald Fraser, Nigel Brunskill, Takafumi Ito, and Aled Phillips Long-Term Exposure of Proximal Tubular Epithelial Cells to Glucose Induces Transforming Growth Factor-ß1 Synthesis via an Autocrine PDGF Loop Am J Pathol 2003 163: 2565-2574. [Abstract] [Full Text] [PDF]

Animal Models: Jack Gauldie, Tom Galt, Philippe Bonniaud, Clinton Robbins, Margaret Kelly, and David Warburton Transfer of the Active Form of Transforming Growth Factor-ß1 Gene to Newborn Rat Lung Induces Changes Consistent with Bronchopulmonary Dysplasia Am J Pathol 2003 163: 2575-2584. [Abstract] [Full Text] [PDF]   Yuzuru Taguchi, Shirou Mohri, James W. Ironside, Tamaki Muramoto, and Tetsuyuki Kitamoto Humanized Knock-In Mice Expressing Chimeric Prion Protein Showed Varied Susceptibility to Different Human Prions Am J Pathol 2003 163: 2585-2593. [Abstract] [Full Text] [PDF]   Reza J. Rasoulpour, Heidi A. Schoenfeld, Douglas A. Gray, and Kim Boekelheide Expression of a K48R Mutant Ubiquitin Protects Mouse Testis from Cryptorchid Injury and Aging Am J Pathol 2003 163: 2595-2603. [Abstract] [Full Text] [PDF]   Claudia F. Benjamim, Cory M. Hogaboam, Nicholas W. Lukacs, and Steven L. Kunkel Septic Mice Are Susceptible to Pulmonary Aspergillosis Am J Pathol 2003 163: 2605-2617. [Abstract] [Full Text] [PDF]   Federica Sotgia, Gloria Bonuccelli, Carlo Minetti, Scott E. Woodman, Franco Capozza, Robert G. Kemp, Philipp E. Scherer, and Michael P. Lisanti Phosphofructokinase Muscle-Specific Isoform Requires Caveolin-3 Expression for Plasma Membrane Recruitment and Caveolar Targeting: Implications for the Pathogenesis of Caveolin-Related Muscle Diseases Am J Pathol 2003 163: 2619-2634. [Abstract] [Full Text] [PDF]

Correspondence: Hidefumi Sasaki, Yoshitaka Fujii, Nobuyuki Ide, and Petr Starostik Chromosome 6 Abnormalities Correlated with Thymoma Progression Am J Pathol 2003 163: 2635-2636. [Full Text] [PDF]   Martin Flück, Thomas Gustafsson, Tuomas Rissanen, and Seppo Ylä-Herttuala VEGF Protein in Human Ischemic Skeletal Muscle Am J Pathol 2003 163: 2636-2638. [Full Text] [PDF]   Torsten Goldmann, Ekkehard Vollmer, and Johannes Gerdes What’s Cooking? Detection of Important Biomarkers in HOPE-Fixed, Paraffin-Embedded Tissues Eliminates the Need for Antigen Retrieval Am J Pathol 2003 163: 2638-2640. [Full Text] [PDF]   Jiri T. Beranek, Tarek El-Sawy, and Robert L. Fairchild Unusual Apoptosis in Experimental Cardiac Rejection Am J Pathol 2003 163: 2640-2642. [Full Text] [PDF]   Mohammad Reza Namazi and Victoria Kolb-Bachofen Explaining Decreased Nitric Oxide Production in Psoriatic Lesions: Arginase 1 Overexpression versus Calcitonin Gene-Related Peptide Am J Pathol 2003 163: 2642-2643. [Full Text] [PDF]

Correction: Corrections Am J Pathol 2003 163: 2645-2646. [Full Text] [PDF]

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