Short Communications: Gaetano Vattemi, W. King Engel, Janis McFerrin, and Valerie Askanas Endoplasmic Reticulum Stress and Unfolded Protein Response in Inclusion Body Myositis Muscle Am J Pathol 2004 164: 1-7. [Abstract] [Full Text]   Greg Bloom, Ivana V. Yang, David Boulware, Ka Yin Kwong, Domenico Coppola, Steven Eschrich, John Quackenbush, and Timothy J. Yeatman Multi-Platform, Multi-Site, Microarray-Based Human Tumor Classification Am J Pathol 2004 164: 9-16. [Abstract] [Full Text]   Rainer Lehtonen, Maija Kiuru, Sakari Vanharanta, Jari Sjöberg, Leena-Maija Aaltonen, Kristiina Aittomäki, Johanna Arola, Ralf Butzow, Charis Eng, Kirsti Husgafvel-Pursiainen, Jorma Isola, Heikki Järvinen, Pasi Koivisto, Jukka-Pekka Mecklin, Päivi Peltomäki, Reijo Salovaara, Veli-Matti Wasenius, Auli Karhu, Virpi Launonen, Nina N. Nupponen, and Lauri A. Aaltonen Biallelic Inactivation of Fumarate Hydratase (FH) Occurs in Nonsyndromic Uterine Leiomyomas but Is Rare in Other Tumors Am J Pathol 2004 164: 17-22. [Abstract] [Full Text]

Technical Advances: Martha S. Rook, Scott M. Delach, Galina Deyneko, Andrew Worlock, and Jia Liu Wolfe Whole Genome Amplification of DNA from Laser Capture-Microdissected Tissue for High-Throughput Single Nucleotide Polymorphism and Short Tandem Repeat Genotyping Am J Pathol 2004 164: 23-33. [Abstract] [Full Text]   Maureen Cronin, Mylan Pho, Debjani Dutta, James C. Stephans, Steven Shak, Michael C. Kiefer, Jose M. Esteban, and Joffre B. Baker Measurement of Gene Expression in Archival Paraffin-Embedded Tissues: Development and Performance of a 92-Gene Reverse Transcriptase-Polymerase Chain Reaction Assay Am J Pathol 2004 164: 35-42. [Abstract] [Full Text]   Daniel L. Myers and Lucy Liaw Improved Analysis of the Vascular Response to Arterial Ligation Using a Multivariate Approach Am J Pathol 2004 164: 43-48. [Abstract] [Full Text]

Regular Articles: Michael B. Drennan, Delphine Nicolle, Valerie J. F. Quesniaux, Muazzam Jacobs, Nasiema Allie, Joseph Mpagi, Cécile Frémond, Hermann Wagner, Carsten Kirschning, and Bernhard Ryffel Toll-Like Receptor 2-Deficient Mice Succumb to Mycobacterium tuberculosis Infection Am J Pathol 2004 164: 49-57. [Abstract] [Full Text]   Takayuki Harada, Chikako Harada, Yu-Lai Wang, Hitoshi Osaka, Kazuhito Amanai, Kohichi Tanaka, Shuichi Takizawa, Rieko Setsuie, Mikako Sakurai, Yae Sato, Mami Noda, and Keiji Wada Role of Ubiquitin Carboxy Terminal Hydrolase-L1 in Neural Cell Apoptosis Induced by Ischemic Retinal Injury in Vivo Am J Pathol 2004 164: 59-64. [Abstract] [Full Text]   Andreas Gebert, Ivo Steinmetz, Susanne Fassbender, and Karl-Heinz Wendlandt Antigen Transport into Peyer’s Patches: Increased Uptake by Constant Numbers of M Cells Am J Pathol 2004 164: 65-72. [Abstract] [Full Text]   Juana Maria Garcia Pedrero, M. Pilar Fernandez, Reginald O. Morgan, Agustin Herrero Zapatero, Maria Victoria Gonzalez, Carlos Suarez Nieto, and Juan Pablo Rodrigo Annexin A1 Down-Regulation in Head and Neck Cancer Is Associated with Epithelial Differentiation Status Am J Pathol 2004 164: 73-79. [Abstract] [Full Text]   Stephanie Kwei, George Stavrakis, Masaya Takahas, George Taylor, M. Judah Folkman, Michael A. Gimbrone, Jr, and Guillermo García-Cardeña Early Adaptive Responses of the Vascular Wall during Venous Arterialization in Mice Am J Pathol 2004 164: 81-89. [Abstract] [Full Text]   Koji Okudela, Hiroyuki Hayashi, Takaaki Ito, Takuya Yazawa, Takehisa Suzuki, Yuko Nakane, Hanako Sato, Haruhiko Ishi, Xin KeQin, Akira Masuda, Takashi Takahashi, and Hitoshi Kitamura K-ras Gene Mutation Enhances Motility of Immortalized Airway Cells and Lung Adenocarcinoma Cells via Akt Activation: Possible Contribution to Non-Invasive Expansion of Lung Adenocarcinoma Am J Pathol 2004 164: 91-100. [Abstract] [Full Text]   Daniëlle M. J. Curfs, Esther Lutgens, Marion J. J. Gijbels, Mark M. Kockx, Mat J. A. P. Daemen, and Frederik J. van Schooten Chronic Exposure to the Carcinogenic Compound Benzo[a]Pyrene Induces Larger and Phenotypically Different Atherosclerotic Plaques in ApoE-Knockout Mice Am J Pathol 2004 164: 101-108. [Abstract] [Full Text]   Yuan H. Yang, Pam Hall, Georgia Milenkovski, Laveena Sharma, Paul Hutchinson, Els Melis, Peter Carmeliet, Peter Tipping, and Eric Morand Reduction in Arthritis Severity and Modulation of Immune Function in Tissue Factor Cytoplasmic Domain Mutant Mice Am J Pathol 2004 164: 109-117. [Abstract] [Full Text]   Aleksander Hinek, Kathy R. Braun, Kela Liu, Yanting Wang, and Thomas N. Wight Retrovirally Mediated Overexpression of Versican V3 Reverses Impaired Elastogenesis and Heightened Proliferation Exhibited by Fibroblasts from Costello Syndrome and Hurler Disease Patients Am J Pathol 2004 164: 119-131. [Abstract] [Full Text]   Conrad A. Farrar, Yi Wang, Steven H. Sacks, and Wuding Zhou Independent Pathways of P-Selectin and Complement-Mediated Renal Ischemia/Reperfusion Injury Am J Pathol 2004 164: 133-141. [Abstract] [Full Text]   Mark W. Head, Diane Ritchie, Nadine Smith, Victoria McLoughlin, William Nailon, Sazia Samad, Stephen Masson, Matthew Bishop, Linda McCardle, and James W. Ironside Peripheral Tissue Involvement in Sporadic, Iatrogenic, and Variant Creutzfeldt-Jakob Disease: An Immunohistochemical, Quantitative, and Biochemical Study Am J Pathol 2004 164: 143-153. [Abstract] [Full Text]   Deepa V. Dabir, John Q. Trojanowski, Christiane Richter-Landsberg, Virginia M.-Y. Lee, and Mark S. Forman Expression of the Small Heat-Shock Protein B-Crystallin in Tauopathies with Glial Pathology Am J Pathol 2004 164: 155-166. [Abstract] [Full Text]   Parley D. Fillmore, Elizabeth P. Blankenhorn, James F. Zachary, and Cory Teuscher Adult Gonadal Hormones Selectively Regulate Sexually Dimorphic Quantitative Traits Observed in Experimental Allergic Encephalomyelitis Am J Pathol 2004 164: 167-175. [Abstract] [Full Text]   Martine Chabaud-Riou and Gary S. Firestein Expression and Activation of Mitogen-Activated Protein Kinase Kinases-3 and -6 in Rheumatoid Arthritis Am J Pathol 2004 164: 177-184. [Abstract] [Full Text]   Thomas Pufe, Angelika Lemke, Bodo Kurz, Wolf Petersen, Bernhard Tillmann, Alan J. Grodzinsky, and Rolf Mentlein Mechanical Overload Induces VEGF in Cartilage Discs via Hypoxia-Inducible Factor Am J Pathol 2004 164: 185-192. [Abstract] [Full Text]   Soledad R. Alonso, Pablo Ortiz, Marina Pollán, Beatriz Pérez-Gómez, Lydia Sánchez, Ma Jesús Acuña, Raquel Pajares, Francisco J. Martínez-Tello, Carlos M. Hortelano, Miguel A. Piris, and José L. Rodríguez-Peralto Progression in Cutaneous Malignant Melanoma Is Associated with Distinct Expression Profiles: A Tissue Microarray-Based Study Am J Pathol 2004 164: 193-203. [Abstract] [Full Text] Supplemental Material   Kwesi Teye, Makoto Tsuneoka, Nobuyuki Arima, Yoshiro Koda, Yasuhiro Nakamura, Yoichi Ueta, Kazuo Shirouzu, and Hiroshi Kimura Increased Expression of a Myc Target Gene Mina53 in Human Colon Cancer Am J Pathol 2004 164: 205-216. [Abstract] [Full Text]   Jeff Holzbeierlein, Priti Lal, Eva LaTulippe, Alex Smith, Jaya Satagopan, Liying Zhang, Charles Ryan, Steve Smith, Howard Scher, Peter Scardino, Victor Reuter, and William L. Gerald Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance Am J Pathol 2004 164: 217-227. [Abstract] [Full Text] Supplemental Material   Lari Häkkinen, Leeni Koivisto, Humphrey Gardner, Ulpu Saarialho-Kere, Joseph M. Carroll, Merja Lakso, Heikki Rauvala, Matti Laato, Jyrki Heino, and Hannu Larjava Increased Expression of ß6-Integrin in Skin Leads to Spontaneous Development of Chronic Wounds Am J Pathol 2004 164: 229-242. [Abstract] [Full Text]   Xian Wu Cheng, Masafumi Kuzuya, Takeshi Sasaki, Koji Arakawa, Shigeru Kanda, Daigo Sumi, Teruhiko Koike, Keiko Maeda, Norika Tamaya-Mori, Guo-Ping Shi, Noboru Saito, and Akihisa Iguchi Increased Expression of Elastolytic Cysteine Proteases, Cathepsins S and K, in the Neointima of Balloon-Injured Rat Carotid Arteries Am J Pathol 2004 164: 243-251. [Abstract] [Full Text]   Steven Greenway, Robert Jan van Suylen, Gideon Du Marchie Sarvaas, Edwin Kwan, Noona Ambartsumian, Eugene Lukanidin, and Marlene Rabinovitch S100A4/Mts1 Produces Murine Pulmonary Artery Changes Resembling Plexogenic Arteriopathy and Is Increased in Human Plexogenic Arteriopathy Am J Pathol 2004 164: 253-262. [Abstract] [Full Text]   Hamida Hammad, Hendrik Jan de Heer, Thomas Soullié, Véronique Angeli, François Trottein, Henk C. Hoogsteden, and Bart N. Lambrecht Activation of Peroxisome Proliferator-Activated Receptor- in Dendritic Cells Inhibits the Development of Eosinophilic Airway Inflammation in a Mouse Model of Asthma Am J Pathol 2004 164: 263-271. [Abstract] [Full Text]   Jonathan R. Brody, Shrihari S. Kadkol, M. Claire Hauer, Fatemeh Rajaii, Jessica Lee, and Gary R. Pasternack pp32 Reduction Induces Differentiation of TSU-Pr1 Cells Am J Pathol 2004 164: 273-283. [Abstract] [Full Text]   Andrew J. Evans, Brenda L. Gallie, Michael A.S. Jewett, Gregory R. Pond, Kirk Vandezande, John Underwood, Yves Fradet, Gloria Lim, Paula Marrano, Maria Zielenska, and Jeremy A. Squire Defining a 0.5-Mb Region of Genomic Gain on Chromosome 6p22 in Bladder Cancer by Quantitative-Multiplex Polymerase Chain Reaction Am J Pathol 2004 164: 285-293. [Abstract] [Full Text]   Craig M. Schramm, Lynn Puddington, Carol Wu, Linda Guernsey, Mehrnaz Gharaee-Kermani, Sem H. Phan, and Roger S. Thrall Chronic Inhaled Ovalbumin Exposure Induces Antigen-Dependent but Not Antigen-Specific Inhalational Tolerance in a Murine Model of Allergic Airway Disease Am J Pathol 2004 164: 295-304. [Abstract] [Full Text]   Kathleen Kemmer, Christopher L. Corless, Jonathan A. Fletcher, Laura McGreevey, Andrea Haley, Diana Griffith, Oscar W. Cummings, Cecily Wait, Ajia Town, and Michael C. Heinrich KIT Mutations Are Common in Testicular Seminomas Am J Pathol 2004 164: 305-313. [Abstract] [Full Text]   Derek D. Sloan, Ben Nicholson, Virginia Urquidi, and Steve Goodison Detection of Differentially Expressed Genes in an Isogenic Breast Metastasis Model using RNA Arbitrarily Primed-Polymerase Chain Reaction Coupled with Array Hybridization (RAP-Array) Am J Pathol 2004 164: 315-323. [Abstract] [Full Text]

Animal Models: Katerina Politi, Matthias Szabolcs, Peter Fisher, Ana Kljuic, Thomas Ludwig, and Argiris Efstratiadis A Mouse Model of Uterine Leiomyosarcoma Am J Pathol 2004 164: 325-336. [Abstract] [Full Text]   Yutaka Takaoka, Mika Ohta, Kazuhisa Miyakawa, Osamu Nakamura, Misao Suzuki, Kiyoshi Takahashi, Ken-ichi Yamamura, and Yoshiyuki Sakaki Cysteine 10 Is a Key Residue in Amyloidogenesis of Human Transthyretin Val30Met Am J Pathol 2004 164: 337-345. [Abstract] [Full Text]   Ronald L. Klein, Wen-Lang Lin, Dennis W. Dickson, Jada Lewis, Michael Hutton, Karen Duff, Edwin M. Meyer, and Michael A. King Rapid Neurofibrillary Tangle Formation after Localized Gene Transfer of Mutated Tau Am J Pathol 2004 164: 347-353. [Abstract] [Full Text]

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