The Cover: Confocal micrograph showing abundant strands of vascular basement membrane (type IV collagen immunoreactivity, red) in a tumor after endothelial cells (CD31 immunoreactivity, yellow-green) of blood vessels regressed in response to treatment with an inhibitor of VEGF signaling. Basement membrane strands serve as a historical record of the number and location of tumor vessels present before treatment. (See page 35).