Commentaries: David H. Cribbs, Wayne W. Poon, Robert A. Rissman, and Mathew Blurton-Jones Caspase-Mediated Degeneration in Alzheimer’s Disease Am J Pathol 2004 165: 353-355. [Full Text]

Regular Articles: Xiao-Han Chen, Robert Siman, Akira Iwata, David F. Meaney, John Q. Trojanowski, and Douglas H. Smith Long-Term Accumulation of Amyloid-ß, ß-Secretase, Presenilin-1, and Caspase-3 in Damaged Axons Following Brain Trauma Am J Pathol 2004 165: 357-371. [Abstract] [Full Text]   Cristiano Rumio, Dario Besusso, Marco Palazzo, Silvia Selleri, Lucia Sfondrini, Francesco Dubini, Sylvie Ménard, and Andrea Balsari Degranulation of Paneth Cells via Toll-Like Receptor 9 Am J Pathol 2004 165: 373-381. [Abstract] [Full Text]   Liliana Schaefer, Daniel Mihalik, Andrea Babelova, Miroslava Krzyzankova, Hermann-Josef Gröne, Renato V. Iozzo, Marian F. Young, Daniela G. Seidler, Guoqing Lin, Dieter P. Reinhardt, and Roland M. Schaefer Regulation of Fibrillin-1 by Biglycan and Decorin Is Important for Tissue Preservation in the Kidney During Pressure-Induced Injury Am J Pathol 2004 165: 383-396. [Abstract] [Full Text]   Kathleen Hibbs, Keith M. Skubitz, Stefan E. Pambuccian, Rachael C. Casey, Kathryn M. Burleson, Theodore R. Oegema, Jr, Jeannine J. Thiele, Suzanne M. Grindle, Robin L. Bliss, and Amy P.N. Skubitz Differential Gene Expression in Ovarian Carcinoma: Identification of Potential Biomarkers Am J Pathol 2004 165: 397-414. [Abstract] [Full Text]   Qing Li and Bjorn R. Olsen Increased Angiogenic Response in Aortic Explants of Collagen XVIII/Endostatin-Null Mice Am J Pathol 2004 165: 415-424. [Abstract] [Full Text]   Sabine Kersting, Matthias Bruewer, Guido Schuermann, Axel Klotz, Markus Utech, Matthias Hansmerten, Christian F. Krieglstein, Norbert Senninger, Joerg-Dieter Schulzke, Hassan Y. Naim, and Klaus-Peter Zimmer Antigen Transport and Cytoskeletal Characteristics of a Distinct Enterocyte Population in Inflammatory Bowel Diseases Am J Pathol 2004 165: 425-437. [Abstract] [Full Text]   Koichi Kaikita, Takanori Hayasaki, Toshiyuki Okuma, William A. Kuziel, Hisao Ogawa, and Motohiro Takeya Targeted Deletion of CC Chemokine Receptor 2 Attenuates Left Ventricular Remodeling after Experimental Myocardial Infarction Am J Pathol 2004 165: 439-447. [Abstract] [Full Text]   Michael Samoszuk, Tom Deng, Mark J. Hamamura, Min-Ying Su, Nicholas Asbrock, and Orhan Nalcioglu Increased Blood Clotting, Microvascular Density, and Inflammation in Eotaxin-Secreting Tumors Implanted into Mice Am J Pathol 2004 165: 449-456. [Abstract] [Full Text]   Vassiliki Poulaki, Antonia M. Joussen, Nicholas Mitsiades, Constantine S. Mitsiades, Eirini F. Iliaki, and Anthony P. Adamis Insulin-Like Growth Factor-I Plays a Pathogenetic Role in Diabetic Retinopathy Am J Pathol 2004 165: 457-469. [Abstract] [Full Text]   Hirofumi Nakanishi, Kiyoko Yoshioka, Susumu Joyama, Nobuhito Araki, Akira Myoui, Shingo Ishiguro, Takafumi Ueda, Hideki Yoshikawa, and Kazuyuki Itoh Interleukin-6/Soluble Interleukin-6 Receptor Signaling Attenuates Proliferation and Invasion, and Induces Morphological Changes of a Newly Established Pleomorphic Malignant Fibrous Histiocytoma Cell Line Am J Pathol 2004 165: 471-480. [Abstract] [Full Text]   Tiemo Katzenberger, German Ott, Thomas Klein, Jörg Kalla, Hans Konrad Müller-Hermelink, and M. Michaela Ott Cytogenetic Alterations Affecting BCL6 Are Predominantly Found in Follicular Lymphomas Grade 3B with a Diffuse Large B-Cell Component Am J Pathol 2004 165: 481-490. [Abstract] [Full Text]   Eiichi Morii, Akihiko Ito, Tomoko Jippo, Yu-ichiro Koma, Keisuke Oboki, Tomohiko Wakayama, Shoichi Iseki, M. Lynn Lamoreux, and Yukihiko Kitamura Number of Mast Cells in the Peritoneal Cavity of Mice: Influence of Microphthalmia Transcription Factor through Transcription of Newly Found Mast Cell Adhesion Molecule, Spermatogenic Immunoglobulin Superfamily Am J Pathol 2004 165: 491-499. [Abstract] [Full Text]   Hirohiko Ise, Toshio Nikaido, Naoki Negishi, Nobuhiro Sugihara, Fumitaka Suzuki, Toshihiro Akaike, and Uichi Ikeda Effective Hepatocyte Transplantation Using Rat Hepatocytes with Low Asialoglycoprotein Receptor Expression Am J Pathol 2004 165: 501-510. [Abstract] [Full Text]   Rosa Marina Melillo, Anna Maria Cirafici, Valentina De Falco, Marie Bellantoni, Gennaro Chiappetta, Alfredo Fusco, Francesca Carlomagno, Antonella Picascia, Donatella Tramontano, Giovanni Tallini, and Massimo Santoro The Oncogenic Activity of RET Point Mutants for Follicular Thyroid Cells May Account for the Occurrence of Papillary Thyroid Carcinoma in Patients Affected by Familial Medullary Thyroid Carcinoma Am J Pathol 2004 165: 511-521. [Abstract] [Full Text]   Huishan Guo, Steffen Albrecht, Martine Bourdeau, Tracy Petzke, Catherine Bergeron, and Andrea C. LeBlanc Active Caspase-6 and Caspase-6-Cleaved Tau in Neuropil Threads, Neuritic Plaques, and Neurofibrillary Tangles of Alzheimer’s Disease Am J Pathol 2004 165: 523-531. [Abstract] [Full Text]   Koh-ichi Nakashiro, Shingo Hara, Yuji Shinohara, Miho Oyasu, Hitoshi Kawamata, Satoru Shintani, Hiroyuki Hamakawa, and Ryoichi Oyasu Phenotypic Switch from Paracrine to Autocrine Role of Hepatocyte Growth Factor in an Androgen-Independent Human Prostatic Carcinoma Cell Line, CWR22R Am J Pathol 2004 165: 533-540. [Abstract] [Full Text]   Karen O. Yee, Michael Streit, Thomas Hawighorst, Michael Detmar, and Jack Lawler Expression of the Type-1 Repeats of Thrombospondin-1 Inhibits Tumor Growth Through Activation of Transforming Growth Factor-ß Am J Pathol 2004 165: 541-552. [Abstract] [Full Text]   David Waltregny, Laurence de Leval, Wendy Glénisson, Siv Ly Tran, Brian J. North, Akeila Bellahcène, Ulrich Weidle, Eric Verdin, and Vincent Castronovo Expression of Histone Deacetylase 8, a Class I Histone Deacetylase, Is Restricted to Cells Showing Smooth Muscle Differentiation in Normal Human Tissues Am J Pathol 2004 165: 553-564. [Abstract] [Full Text]   Carl Morrison, William Farrar, Jeff Kneile, Nita Williams, Yiwen Liu-Stratton, Alan Bakaletz, Micheala A. Aldred, and Charis Eng Molecular Classification of Parathyroid Neoplasia by Gene Expression Profiling Am J Pathol 2004 165: 565-576. [Abstract] [Full Text]   Jun-ichi Satoh, Takashi Yamamura, and Kunimasa Arima The 14-3-3 Protein Isoform Expressed in Reactive Astrocytes in Demyelinating Lesions of Multiple Sclerosis Binds to Vimentin and Glial Fibrillary Acidic Protein in Cultured Human Astrocytes Am J Pathol 2004 165: 577-592. [Abstract] [Full Text] Supplemental Material   Jan H.N. Lindeman, Roeland Hanemaaijer, Adri Mulder, P.D. Sander Dijkstra, Károly Szuhai, Dieter Bromme, Jan H. Verheijen, and Pancras C.W. Hogendoorn Cathepsin K Is the Principal Protease in Giant Cell Tumor of Bone Am J Pathol 2004 165: 593-600. [Abstract] [Full Text]   Stephen L. Madden, Brian P. Cook, Mariana Nacht, William D. Weber, Michelle R. Callahan, Yide Jiang, Michael R. Dufault, Xiaoming Zhang, Wen Zhang, Jennifer Walter-Yohrling, Cecile Rouleau, Viatcheslav R. Akmaev, Clarence J. Wang, Xiaohong Cao, Thia B. St. Martin, Bruce L. Roberts, Beverly A. Teicher, Katherine W. Klinger, Radu-Virgil Stan, Brenden Lucey, Eleanor B. Carson-Walter, John Laterra, and Kevin A. Walter Vascular Gene Expression in Nonneoplastic and Malignant Brain Am J Pathol 2004 165: 601-608. [Abstract] [Full Text] Supplemental Material   Christopher G. Kevil, M. John Hicks, Xiaodong He, Junxuan Zhang, Christie M. Ballantyne, Chander Raman, Trenton R. Schoeb, and Daniel C. Bullard Loss of LFA-1, but not Mac-1, Protects MRL/MpJ-Faslpr Mice from Autoimmune Disease Am J Pathol 2004 165: 609-616. [Abstract] [Full Text]   Xiwu Chen, Gilbert Moeckel, Jason D. Morrow, Dominic Cosgrove, Raymond C. Harris, Agnes B. Fogo, Roy Zent, and Ambra Pozzi Lack of Integrin 1ß1 Leads to Severe Glomerulosclerosis after Glomerular Injury Am J Pathol 2004 165: 617-630. [Abstract] [Full Text]   Tetsu Nishiwaki, Hiroyuki Yoneyama, Yoshinobu Eishi, Naoki Matsuo, Koichiro Tatsumi, Hiroshi Kimura, Takayuki Kuriyama, and Kouji Matsushima Indigenous Pulmonary Propionibacterium acnes Primes the Host in the Development of Sarcoid-Like Pulmonary Granulomatosis in Mice Am J Pathol 2004 165: 631-639. [Abstract] [Full Text]   Noriko Asano, Manabu Fujimoto, Norihito Yazawa, Senji Shirasawa, Minoru Hasegawa, Hitoshi Okochi, Kunihiko Tamaki, Thomas F. Tedder, and Shinichi Sato B Lymphocyte Signaling Established by the CD19/CD22 Loop Regulates Autoimmunity in the Tight-Skin Mouse Am J Pathol 2004 165: 641-650. [Abstract] [Full Text]   Michiel S. Van der Heijden, Jonathan R. Brody, Eike Gallmeier, Steven C. Cunningham, David A. Dezentje, Dong Shen, Ralph H. Hruban, and Scott E. Kern Functional Defects in the Fanconi Anemia Pathway in Pancreatic Cancer Cells Am J Pathol 2004 165: 651-657. [Abstract] [Full Text]   Yong Zhou, James S. Hagood, and Joanne E. Murphy-Ullrich Thy-1 Expression Regulates the Ability of Rat Lung Fibroblasts to Activate Transforming Growth Factor-ß in Response to Fibrogenic Stimuli Am J Pathol 2004 165: 659-669. [Abstract] [Full Text]

Animal Models: Julia Schultz, Anja Schwarz, Sabine Neidhold, Michael Burwinkel, Constanze Riemer, Dietrich Simon, Manfred Kopf, Markus Otto, and Michael Baier Role of Interleukin-1 in Prion Disease-Associated Astrocyte Activation Am J Pathol 2004 165: 671-678. [Abstract] [Full Text]   Cindy E.L. Lim, Klaus I. Matthaei, Anneke C. Blackburn, Richard P. Davis, Jane E. Dahlstrom, Mark E. Koina, M.W. Anders, and Philip G. Board Mice Deficient in Glutathione Transferase Zeta/Maleylacetoacetate Isomerase Exhibit a Range of Pathological Changes and Elevated Expression of Alpha, Mu, and Pi Class Glutathione Transferases Am J Pathol 2004 165: 679-693. [Abstract] [Full Text]   Hippokratis Kiaris, Katerina Politi, Lisa M. Grimm, Matthias Szabolcs, Peter Fisher, Argiris Efstratiadis, and Spyros Artavanis-Tsakonas Modulation of Notch Signaling Elicits Signature Tumors and Inhibits Hras1-Induced Oncogenesis in the Mouse Mammary Epithelium Am J Pathol 2004 165: 695-705. [Abstract] [Full Text]

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