Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Roscoe L. Warner, Nicholas W. Lukacs, Steven D. Shapiro, Narasimharao Bhagarvathula, Kamalakar C. Nerusu, James Varani, and Kent J. Johnson Role of Metalloelastase in a Model of Allergic Lung Responses Induced by Cockroach Allergen Am J Pathol 2004 165: 1921-1930. [Abstract] [Full Text]   Guihua Zhou, Cai Li, and Lu Cai Advanced Glycation End-Products Induce Connective Tissue Growth Factor-Mediated Renal Fibrosis Predominantly through Transforming Growth Factor ß-Independent Pathway Am J Pathol 2004 165: 2033-2043. [Abstract] [Full Text]   Riaz I. Zuberi, Daniel K. Hsu, Omer Kalayci, Huan-Yuan Chen, Holly K. Sheldon, Lan Yu, John R. Apgar, Toshiaki Kawakami, Craig M. Lilly, and Fu-Tong Liu Critical Role for Galectin-3 in Airway Inflammation and Bronchial Hyperresponsiveness in a Murine Model of Asthma Am J Pathol 2004 165: 2045-2053. [Abstract] [Full Text]

Epithelial and Mesenchymal Cell Biology: Isao Nozaki, John G. Lunz, III, Susan Specht, Jong-In Park, Andrew S. Giraud, Noriko Murase, and Anthony J. Demetris Regulation and Function of Trefoil Factor Family 3 Expression in the Biliary Tree Am J Pathol 2004 165: 1907-1920. [Abstract] [Full Text]   András Masszi, Lingzhi Fan, László Rosivall, Christopher A. McCulloch, Ori D. Rotstein, István Mucsi, and András Kapus Integrity of Cell-Cell Contacts Is a Critical Regulator of TGF-ß1-Induced Epithelial-to-Myofibroblast Transition: Role for ß-Catenin Am J Pathol 2004 165: 1955-1967. [Abstract] [Full Text]   Philippe Mavier, Nadine Martin, Dominique Couchie, Anne-Marie Préaux, Yannick Laperche, and Elie Serge Zafrani Expression of Stromal Cell-Derived Factor-1 and of Its Receptor CXCR4 in Liver Regeneration from Oval Cells in Rat Am J Pathol 2004 165: 1969-1977. [Abstract] [Full Text]   Akira Hachiya, Akemi Kobayashi, Yasuko Yoshida, Takashi Kitahara, Yoshinori Takema, and Genji Imokawa Biphasic Expression of Two Paracrine Melanogenic Cytokines, Stem Cell Factor and Endothelin-1, in Ultraviolet B-Induced Human Melanogenesis Am J Pathol 2004 165: 2099-2109. [Abstract] [Full Text]   Christiane Bierkamp, Stéphanie Bonhoure, Anne Mathieu, Pascal Clerc, Daniel Fourmy, Lucien Pradayrol, Catherine Seva, and Marlène Dufresne Expression of Cholecystokinin-2/Gastrin Receptor in the Murine Pancreas Modulates Cell Adhesion and Cell Differentiation in Vivo Am J Pathol 2004 165: 2135-2145. [Abstract] [Full Text]

Growth Factors, Cytokines, Cell Cycle Molecules: Enrico Lupia, Alberto Goffi, Paolo De Giuli, Ornella Azzolino, Ornella Bosco, Enrico Patrucco, Maria Cristina Vivaldo, Marco Ricca, Matthias P. Wymann, Emilio Hirsch, Giuseppe Montrucchio, and Giorgio Emanuelli Ablation of Phosphoinositide 3-Kinase- Reduces the Severity of Acute Pancreatitis Am J Pathol 2004 165: 2003-2011. [Abstract] [Full Text]   Themis R. Kyriakides, Matt J. Foster, Grant E. Keeney, Annabel Tsai, Cecilia M. Giachelli, Ian Clark-Lewis, Barrett J. Rollins, and Paul Bornstein The CC Chemokine Ligand, CCL2/MCP1, Participates in Macrophage Fusion and Foreign Body Giant Cell Formation Am J Pathol 2004 165: 2157-2166. [Abstract] [Full Text]   Bumseok Kim, Qingquan Tang, Partha S. Biswas, Jun Xu, Raymond M. Schiffelers, Frank Y. Xie, Aslam M. Ansari, Puthupparampil V. Scaria, Martin C. Woodle, Patrick Lu, and Barry T. Rouse Inhibition of Ocular Angiogenesis by siRNA Targeting Vascular Endothelial Growth Factor Pathway Genes: Therapeutic Strategy for Herpetic Stromal Keratitis Am J Pathol 2004 165: 2177-2185. [Abstract] [Full Text]

Immunopathology and Infectious Disease: Shayne C. Barlow, Will Langston, Kametra M. Matthews, John H. Chidlow, Jr, and Christopher G. Kevil CD18 Deficiency Protects against Multiple Low-Dose Streptozotocin-Induced Diabetes Am J Pathol 2004 165: 1849-1852. [Abstract] [Full Text]   DeLisa Fairweather, Sylvia Frisancho-Kiss, Susy A. Yusung, Masheka A. Barrett, Sarah E. Davis, Shannon J.L. Gatewood, Dolores B. Njoku, and Noel R. Rose Interferon- Protects against Chronic Viral Myocarditis by Reducing Mast Cell Degranulation, Fibrosis, and the Profibrotic Cytokines Transforming Growth Factor-ß1, Interleukin-1ß, and Interleukin-4 in the Heart Am J Pathol 2004 165: 1883-1894. [Abstract] [Full Text]   Lisa Kercher, Cynthia Favara, Chi-Chao Chan, Richard Race, and Bruce Chesebro Differences in Scrapie-Induced Pathology of the Retina and Brain in Transgenic Mice that Express Hamster Prion Protein in Neurons, Astrocytes, or Multiple Cell Types Am J Pathol 2004 165: 2055-2067. [Abstract] [Full Text]   Yong Wook Park, Young Mo Kang, Joe Butterfield, Michael Detmar, Jörg J. Goronzy, and Cornelia M. Weyand Thrombospondin 2 Functions as an Endogenous Regulator of Angiogenesis and Inflammation in Rheumatoid Arthritis Am J Pathol 2004 165: 2087-2098. [Abstract] [Full Text]   Juan T. Borda, Xavier Alvarez, Ivanela Kondova, Pyone Aye, Meredith A. Simon, Ronald C. Desrosiers, and Andrew A. Lackner Cell Tropism of Simian Immunodeficiency Virus in Culture Is Not Predictive of in Vivo Tropism or Pathogenesis Am J Pathol 2004 165: 2111-2122. [Abstract] [Full Text]   Christian R. Engwerda, Manabu Ato, Simona Stäger, Clare E. Alexander, Amanda C. Stanley, and Paul M. Kaye Distinct Roles for Lymphotoxin- and Tumor Necrosis Factor in the Control of Leishmania donovani Infection Am J Pathol 2004 165: 2123-2133. [Abstract] [Full Text]   Cecilia L. Speyer, Hongwei Gao, Nicholas J. Rancilio, Thomas A. Neff, Gary B. Huffnagle, J. Vidya Sarma, and Peter A. Ward Novel Chemokine Responsiveness and Mobilization of Neutrophils during Sepsis Am J Pathol 2004 165: 2187-2196. [Abstract] [Full Text]

Musculoskeletal Pathology: Jung-Eun Kim, Kazuhisa Nakashima, and Benoit de Crombrugghe Transgenic Mice Expressing a Ligand-Inducible Cre Recombinase in Osteoblasts and Odontoblasts: A New Tool to Examine Physiology and Disease of Postnatal Bone and Tooth Am J Pathol 2004 165: 1875-1882. [Abstract] [Full Text]

Neurobiology: Magdalena J. Polanczyk, Richard E. Jones, Sandhya Subramanian, Michael Afentoulis, Cathleen Rich, Melissa Zakroczymski, Paul Cooke, Arthur A. Vandenbark, and Halina Offner T Lymphocytes Do Not Directly Mediate the Protective Effect of Estrogen on Experimental Autoimmune Encephalomyelitis Am J Pathol 2004 165: 2069-2077. [Abstract] [Full Text]   Francesca Ruffini, Nathalie Arbour, Manon Blain, André Olivier, and Jack P. Antel Distinctive Properties of Human Adult Brain-Derived Myelin Progenitor Cells Am J Pathol 2004 165: 2167-2175. [Abstract] [Full Text]   Syaun Sung, Hengxuan Yang, Kunihiro Uryu, Edward B. Lee, Lei Zhao, Diana Shineman, John Q. Trojanowski, Virginia M.-Y. Lee, and Domenico Praticò Modulation of Nuclear Factor-B Activity by Indomethacin Influences Aß Levels but Not Aß Precursor Protein Metabolism in a Model of Alzheimer’s Disease Am J Pathol 2004 165: 2197-2206. [Abstract] [Full Text]

Tumorigenesis and Neoplastic Progression: Gianni Gerlini, Adrian Tun-Kyi, Christa Dudli, Günter Burg, Nicola Pimpinelli, and Frank O. Nestle Metastatic Melanoma Secreted IL-10 Down-Regulates CD1 Molecules on Dendritic Cells in Metastatic Tumor Lesions Am J Pathol 2004 165: 1853-1863. [Abstract] [Full Text]   Sho-ichi Yamagishi, Riichiro Abe, Yosuke Inagaki, Kazuo Nakamura, Hiroshi Sugawara, Daisuke Inokuma, Hideki Nakamura, Tadamichi Shimizu, Masayoshi Takeuchi, Akihiko Yoshimura, Richard Bucala, Hiroshi Shimizu, and Tsutomu Imaizumi Minodronate, a Newly Developed Nitrogen-Containing Bisphosphonate, Suppresses Melanoma Growth and Improves Survival in Nude Mice by Blocking Vascular Endothelial Growth Factor Signaling Am J Pathol 2004 165: 1865-1874. [Abstract] [Full Text]   Malathy P.V. Shekhar, Pratima Nangia-Makker, Larry Tait, Fred Miller, and Avraham Raz Alterations in Galectin-3 Expression and Distribution Correlate with Breast Cancer Progression: Functional Analysis of Galectin-3 in Breast Epithelial-Endothelial Interactions Am J Pathol 2004 165: 1931-1941. [Abstract] [Full Text]   Chi-Ming Li, Connie E. Kim, Adam A. Margolin, Meirong Guo, Jimmy Zhu, Jacqueline M. Mason, Terrence W. Hensle, Vundavalli V.V.S. Murty, Paul E. Grundy, Eric R. Fearon, Vivette D’Agati, Jonathan D. Licht, and Benjamin Tycko CTNNB1 Mutations and Overexpression of Wnt/ß-Catenin Target Genes in WT1-Mutant Wilms’ Tumors Am J Pathol 2004 165: 1943-1953. [Abstract] [Full Text]   Michael Mengel, Danny Jonigk, Ludwig Wilkens, Jörg Radermacher, Reinhard von Wasielewski, Ulrich Lehmann, Hermann Haller, Michael Mihatsch, and Hans Kreipe Chimerism of Metanephric Adenoma but Not of Carcinoma in Kidney Transplants Am J Pathol 2004 165: 2079-2085. [Abstract] [Full Text]   Shojiro Kitajima, Yasusei Kudo, Ikuko Ogawa, Tarig Bashir, Masae Kitagawa, Mutsumi Miyauchi, Michele Pagano, and Takashi Takata Role of Cks1 Overexpression in Oral Squamous Cell Carcinomas: Cooperation with Skp2 in Promoting p27 Degradation Am J Pathol 2004 165: 2147-2155. [Abstract] [Full Text]

Vascular Biology, Atherosclerosis and Endothelium Biology: Jolanta E. Pitera, Adrian S. Woolf, Nicholas W. Gale, George D. Yancopoulos, and Hai Tao Yuan Dysmorphogenesis of Kidney Cortical Peritubular Capillaries in Angiopoietin-2-Deficient Mice Am J Pathol 2004 165: 1895-1906. [Abstract] [Full Text]   Tetsuhiro Tanaka, Toshio Miyata, Reiko Inagi, Toshiro Fujita, and Masaomi Nangaku Hypoxia in Renal Disease with Proteinuria and/or Glomerular Hypertension Am J Pathol 2004 165: 1979-1992. [Abstract] [Full Text]   Timi Martelius, Ville Salaspuro, Marko Salmi, Leena Krogerus, Krister Höckerstedt, Sirpa Jalkanen, and Irmeli Lautenschlager Blockade of Vascular Adhesion Protein-1 Inhibits Lymphocyte Infiltration in Rat Liver Allograft Rejection Am J Pathol 2004 165: 1993-2001. [Abstract] [Full Text]   Rima Elhage, Pierre Gourdy, Laurent Brouchet, Jacek Jawien, Marie-José Fouque, Catherine Fiévet, Xavier Huc, Yara Barreira, Jean Claude Couloumiers, Jean-François Arnal, and Francis Bayard Deleting TCRß+ or CD4+ T Lymphocytes Leads to Opposite Effects on Site-Specific Atherosclerosis in Female Apolipoprotein E-Deficient Mice Am J Pathol 2004 165: 2013-2018. [Abstract] [Full Text]   Yasuhiro Nakamura, Katsuhide Igarashi, Takashi Suzuki, Jun Kanno, Tohru Inoue, Chika Tazawa, Masayuki Saruta, Tomoko Ando, Noriko Moriyama, Toru Furukawa, Masao Ono, Takuya Moriya, Kiyoshi Ito, Haruo Saito, Tadashi Ishibashi, Shoki Takahashi, Shogo Yamada, and Hironobu Sasano E4F1, a Novel Estrogen-Responsive Gene in Possible Atheroprotection, Revealed by Microarray Analysis Am J Pathol 2004 165: 2019-2031. [Abstract] [Full Text]

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