The Cover: Multilabel confocal microscopy showing infected multinucleated giant cells in lung of macaque infected with simian immunodeficiency virus (SIV). SIV was detected by in situ hybird-ization (red); macrophages were detected with Ham56 (green); cellular nuclei were labeled with To-pro3 (blue) and the unlabeled tissue was visualized by differential interference contrast micros-copy (gray). (See page 2111).