Reviews: Thomas J. Montine and Jason D. Morrow Fatty Acid Oxidation in the Pathogenesis of Alzheimer’s Disease Am J Pathol 2005 166: 1283-1289. [Abstract] [Full Text]

Commentaries: Patricia S. Steeg New Insights into the Tumor Metastatic Process Revealed by Gene Expression Profiling Am J Pathol 2005 166: 1291-1294. [Full Text]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Herman K.W. Tse, Maran B.W. Leung, Adrian S. Woolf, Aswin L. Menke, Nicholas D. Hastie, John A. Gosling, Chi-Pui Pang, and Alisa S.W. Shum Implication of Wt1 in the Pathogenesis of Nephrogenic Failure in a Mouse Model of Retinoic Acid-Induced Caudal Regression Syndrome Am J Pathol 2005 166: 1295-1307. [Abstract] [Full Text]   Marina Morigi, Simona Buelli, Stefania Angioletti, Cristina Zanchi, Lorena Longaretti, Carla Zoja, Miriam Galbusera, Sara Gastoldi, Peter Mundel, Giuseppe Remuzzi, and Ariela Benigni In Response to Protein Load Podocytes Reorganize Cytoskeleton and Modulate Endothelin-1 Gene: Implication for Permselective Dysfunction of Chronic Nephropathies Am J Pathol 2005 166: 1309-1320. [Abstract] [Full Text]   Brigham C. Willis, Janice M. Liebler, Katherine Luby-Phelps, Andrew G. Nicholson, Edward D. Crandall, Roland M. du Bois, and Zea Borok Induction of Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells by Transforming Growth Factor-ß1: Potential Role in Idiopathic Pulmonary Fibrosis Am J Pathol 2005 166: 1321-1332. [Abstract] [Full Text]

Cell Injury, Repair, Aging and Apoptosis: Takahisa Yano, Yoshinori Itoh, Toshio Kubota, Toshiaki Sendo, Tatsuya Koyama, Takuya Fujita, Kumiko Saeki, Akira Yuo, and Ryozo Oishi A Prostacyclin Analog Prevents Radiocontrast Nephropathy via Phosphorylation of Cyclic AMP Response Element Binding Protein Am J Pathol 2005 166: 1333-1342. [Abstract] [Full Text]   James J. Tomasek, Joel McRae, Gary K. Owens, and Carol J. Haaksma Regulation of -Smooth Muscle Actin Expression in Granulation Tissue Myofibroblasts Is Dependent on the Intronic CArG Element and the Transforming Growth Factor-ß1 Control Element Am J Pathol 2005 166: 1343-1351. [Abstract] [Full Text]

Growth Factors, Cytokines, Cell Cycle Molecules: David C.J. Howell, Robin H. Johns, Joseph A. Lasky, Bin Shan, Chris J. Scotton, Geoffrey J. Laurent, and Rachel C. Chambers Absence of Proteinase-Activated Receptor-1 Signaling Affords Protection from Bleomycin-Induced Lung Inflammation and Fibrosis Am J Pathol 2005 166: 1353-1365. [Abstract] [Full Text]   Claus Cursiefen, Sakae Ikeda, Patsy M. Nishina, Richard S. Smith, Akihiro Ikeda, David Jackson, Jun-Song Mo, Lu Chen, M. Reza Dana, Bronislaw Pytowski, Friedrich E. Kruse, and J. Wayne Streilein Spontaneous Corneal Hem- and Lymphangiogenesis in Mice with Destrin-Mutation Depend on VEGFR3 Signaling Am J Pathol 2005 166: 1367-1377. [Abstract] [Full Text]   Mei Wan, Jin Huang, Nirag C. Jhala, Ewan M. Tytler, Lei Yang, Selwyn M. Vickers, Yi Tang, Chongyuan Lu, Ning Wang, and Xu Cao SCFß-TrCP1 Controls Smad4 Protein Stability in Pancreatic Cancer Cells Am J Pathol 2005 166: 1379-1392. [Abstract] [Full Text]   Shizuya Saika, Takeshi Miyamoto, Osamu Yamanaka, Tadashi Kato, Yoshitaka Ohnishi, Kathleen C. Flanders, Kazuo Ikeda, Yuji Nakajima, Winston W.-Y. Kao, Misako Sato, Yasuteru Muragaki, and Akira Ooshima Therapeutic Effect of Topical Administration of SN50, an Inhibitor of Nuclear Factor-B, in Treatment of Corneal Alkali Burns in Mice Am J Pathol 2005 166: 1393-1403. [Abstract] [Full Text]   Shizuya Saika, Kazuo Ikeda, Osamu Yamanaka, Takeshi Miyamoto, Yoshitaka Ohnishi, Misako Sato, Yasuteru Muragaki, Akira Ooshima, Yuji Nakajima, Winston W.-Y. Kao, Kathleen C. Flanders, and Anita B. Roberts Expression of Smad7 in Mouse Eyes Accelerates Healing of Corneal Tissue after Exposure to Alkali Am J Pathol 2005 166: 1405-1418. [Abstract] [Full Text]

Immunopathology and Infectious Disease: Daniel S. Mansur, Erna G. Kroon, Maurício L. Nogueira, Rosa M.E. Arantes, Soraia C.O. Rodrigues, Shizuo Akira, Ricardo T. Gazzinelli, and Marco A. Campos Lethal Encephalitis in Myeloid Differentiation Factor 88-Deficient Mice Infected with Herpes Simplex Virus 1 Am J Pathol 2005 166: 1419-1426. [Abstract] [Full Text]   Florent Sebbane, Donald Gardner, Daniel Long, Brian B. Gowen, and B. Joseph Hinnebusch Kinetics of Disease Progression and Host Response in a Rat Model of Bubonic Plague Am J Pathol 2005 166: 1427-1439. [Abstract] [Full Text]   Monika Bradl, Jan Bauer, Alexander Flügel, Hartmut Wekerle, and Hans Lassmann Complementary Contribution of CD4 and CD8 T Lymphocytes to T-Cell Infiltration of the Intact and the Degenerative Spinal Cord Am J Pathol 2005 166: 1441-1450. [Abstract] [Full Text]

Matrix Pathobiology: Yoshihiro Mimura, Hironobu Ihn, Masatoshi Jinnin, Yoshihide Asano, Kenichi Yamane, and Kunihiko Tamaki Constitutive Thrombospondin-1 Overexpression Contributes to Autocrine Transforming Growth Factor-ß Signaling in Cultured Scleroderma Fibroblasts Am J Pathol 2005 166: 1451-1463. [Abstract] [Full Text]   Michael Anne Gratton, Velidi H. Rao, Daniel T. Meehan, Charles Askew, and Dominic Cosgrove Matrix Metalloproteinase Dysregulation in the Stria Vascularis of Mice with Alport Syndrome: Implications for Capillary Basement Membrane Pathology Am J Pathol 2005 166: 1465-1474. [Abstract] [Full Text]

Neurobiology: Masaru Yamamoto, Masahide Horiba, James L. Buescher, DeReng Huang, Howard E. Gendelman, Richard M. Ransohoff, and Tsuneya Ikezu Overexpression of Monocyte Chemotactic Protein-1/CCL2 in ß-Amyloid Precursor Protein Transgenic Mice Show Accelerated Diffuse ß-Amyloid Deposition Am J Pathol 2005 166: 1475-1485. [Abstract] [Full Text]   Sandra J. Campbell, V. Hugh Perry, Fernando J. Pitossi, Angus G. Butchart, Mariela Chertoff, Sara Waters, Robert Dempster, and Daniel C. Anthony Central Nervous System Injury Triggers Hepatic CC and CXC Chemokine Expression that Is Associated with Leukocyte Mobilization and Recruitment to Both the Central Nervous System and the Liver Am J Pathol 2005 166: 1487-1497. [Abstract] [Full Text]   Dalinda Liazoghli, Sebastien Perreault, Kristina D. Micheva, Mylène Desjardins, and Nicole Leclerc Fragmentation of the Golgi Apparatus Induced by the Overexpression of Wild-Type and Mutant Human Tau Forms in Neurons Am J Pathol 2005 166: 1499-1514. [Abstract] [Full Text]

Tumorigenesis and Neoplastic Progression: Mariarosaria Boccellino, Giovanni Camussi, Alfonso Giovane, Luigi Ferro, Vincenzo Calderaro, Ciro Balestrieri, and Lucio Quagliuolo Platelet-Activating Factor Regulates Cadherin-Catenin Adhesion System Expression and ß-Catenin Phosphorylation during Kaposi’s Sarcoma Cell Motility Am J Pathol 2005 166: 1515-1522. [Abstract] [Full Text]   Li Bai, Hong-Min Ni, Xiaoyun Chen, Daniell DiFrancesca, and Xiao-Ming Yin Deletion of Bid Impedes Cell Proliferation and Hepatic Carcinogenesis Am J Pathol 2005 166: 1523-1532. [Abstract] [Full Text]   Liang Cheng, Timothy D. Jones, Ryan P. McCarthy, John N. Eble, Mingsheng Wang, Gregory T. MacLennan, Antonio Lopez-Beltran, Ximing J. Yang, Michael O. Koch, Shaobo Zhang, Chong-Xian Pan, and Lee Ann Baldridge Molecular Genetic Evidence for a Common Clonal Origin of Urinary Bladder Small Cell Carcinoma and Coexisting Urothelial Carcinoma Am J Pathol 2005 166: 1533-1539. [Abstract] [Full Text]   Keiran S.M. Smalley, Patricia Brafford, Nikolas K. Haass, Johanna M. Brandner, Eric Brown, and Meenhard Herlyn Up-Regulated Expression of Zonula Occludens Protein-1 in Human Melanoma Associates with N-Cadherin and Contributes to Invasion and Adhesion Am J Pathol 2005 166: 1541-1554. [Abstract] [Full Text]   G. Astrid Limb, Karl Matter, Gillian Murphy, Alison D. Cambrey, Paul N. Bishop, Glenn E. Morris, and Peng T. Khaw Matrix Metalloproteinase-1 Associates with Intracellular Organelles and Confers Resistance to Lamin A/C Degradation during Apoptosis Am J Pathol 2005 166: 1555-1563. [Abstract] [Full Text]   Valerie Montel, To-Yu Huang, Evangeline Mose, Kersi Pestonjamasp, and David Tarin Expression Profiling of Primary Tumors and Matched Lymphatic and Lung Metastases in a Xenogeneic Breast Cancer Model Am J Pathol 2005 166: 1565-1579. [Abstract] [Full Text] Supplemental Material

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