In Memoriam: Jeffrey E. Saffitz, Robert E. Schmidt, and Michael L. McDaniel Dr. Paul Eston Lacy, 1924–2005 Am J Pathol 2005 167: 299-300. [Full Text] [PDF]

Commentaries: W. Keith Jones A Murine Model of Alcoholic Cardiomyopathy: A Role for Zinc and Metallothionein in Fibrosis Am J Pathol 2005 167: 301-304. [Full Text] [PDF]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Edecio Cunha-Neto, Victor J. Dzau, Paul D. Allen, Dimitri Stamatiou, Luiz Benvenutti, M. Lourdes Higuchi, Natalia S. Koyama, Joao S. Silva, Jorge Kalil, and Choong-Chin Liew Cardiac Gene Expression Profiling Provides Evidence for Cytokinopathy as a Molecular Mechanism in Chagas’ Disease Cardiomyopathy Am J Pathol 2005 167: 305-313. [Abstract] [Full Text] [PDF] Supplemental Material   Tadeusz Pawelczyk, Marzena Grden, Robert Rzepko, Monika Sakowicz, and Andrzej Szutowicz Region-Specific Alterations of Adenosine Receptors Expression Level in Kidney of Diabetic Rat Am J Pathol 2005 167: 315-325. [Abstract] [Full Text] [PDF]   Akari Inada, Kojiro Nagai, Hidenori Arai, Jun-ichi Miyazaki, Keiko Nomura, Hiroshi Kanamori, Shinya Toyokuni, Yuichiro Yamada, Susan Bonner-Weir, Gordon C. Weir, Atsushi Fukatsu, and Yutaka Seino Establishment of a Diabetic Mouse Model with Progressive Diabetic Nephropathy Am J Pathol 2005 167: 327-336. [Abstract] [Full Text] [PDF]   Lipeng Wang, Zhanxiang Zhou, Jack T. Saari, and Y. James Kang Alcohol-Induced Myocardial Fibrosis in Metallothionein-Null Mice: Prevention by Zinc Supplementation Am J Pathol 2005 167: 337-344. [Abstract] [Full Text] [PDF]

Cell Injury, Repair, Aging and Apoptosis: Diana M. Fries, Richard Lightfoot, Michael Koval, and Harry Ischiropoulos Autologous Apoptotic Cell Engulfment Stimulates Chemokine Secretion by Vascular Smooth Muscle Cells Am J Pathol 2005 167: 345-353. [Abstract] [Full Text] [PDF]   Zheng Feng, Anna Rita Plati, Qing-li Cheng, Mariana Berho, Anita Banerjee, Mylene Potier, Wen-che Jy, Andrew Koff, Liliane J. Striker, and Gary E. Striker Glomerular Aging in Females Is a Multi-Stage Reversible Process Mediated by Phenotypic Changes in Progenitors Am J Pathol 2005 167: 355-363. [Abstract] [Full Text] [PDF]

Epithelial and Mesenchymal Cell Biology: James S. Hagood, Priya Prabhakaran, Pallavi Kumbla, Lorena Salazar, Mark W. MacEwen, Thomas H. Barker, Luis A. Ortiz, Trenton Schoeb, Gene P. Siegal, C. Bruce Alexander, Annie Pardo, and Moisés Selman Loss of Fibroblast Thy-1 Expression Correlates with Lung Fibrogenesis Am J Pathol 2005 167: 365-379. [Abstract] [Full Text] [PDF]   Tetsuya Kawakita, Edgar M. Espana, Hua He, Wei Li, Chia-Yiang Liu, and Scheffer C.G. Tseng Intrastromal Invasion by Limbal Epithelial Cells Is Mediated by Epithelial-Mesenchymal Transition Activated by Air Exposure Am J Pathol 2005 167: 381-393. [Abstract] [Full Text] [PDF] Supplemental Material   Craig Slattery, Eric Campbell, Tara McMorrow, and Michael P. Ryan Cyclosporine A-Induced Renal Fibrosis: A Role for Epithelial-Mesenchymal Transition Am J Pathol 2005 167: 395-407. [Abstract] [Full Text] [PDF]

Growth Factors, Cytokines, Cell Cycle Molecules: Kenneth B.R. Ewan, Hellen A. Oketch-Rabah, Shraddha A. Ravani, G. Shyamala, Harold L. Moses, and Mary Helen Barcellos-Hoff Proliferation of Estrogen Receptor--Positive Mammary Epithelial Cells Is Restrained by Transforming Growth Factor-ß1 in Adult Mice Am J Pathol 2005 167: 409-417. [Abstract] [Full Text] [PDF]   Cristina Colarossi, Yan Chen, Hiroto Obata, Vladimir Jurukovski, Laura Fontana, Branka Dabovic, and Daniel B. Rifkin Lung Alveolar Septation Defects in Ltbp-3-Null Mice Am J Pathol 2005 167: 419-428. [Abstract] [Full Text] [PDF]   Chunsun Dai, Chang-Goo Huh, Snorri S. Thorgeirsson, and Youhua Liu ß-Cell-Specific Ablation of the Hepatocyte Growth Factor Receptor Results in Reduced Islet Size, Impaired Insulin Secretion, and Glucose Intolerance Am J Pathol 2005 167: 429-436. [Abstract] [Full Text] [PDF]

Immunopathology and Infectious Disease: Xuan-Yu Wang, Maria-Giuliana Vannucchi, Florentine Nieuwmeyer, Jing Ye, Maria-Simonetta Faussone-Pellegrini, and Jan Dirk Huizinga Changes in Interstitial Cells of Cajal at the Deep Muscular Plexus Are Associated with Loss of Distention-Induced Burst-Type Muscle Activity in Mice Infected by Trichinella spiralis Am J Pathol 2005 167: 437-453. [Abstract] [Full Text] [PDF]   Thomas C. Greenough, Angela Carville, James Coderre, Mohan Somasundaran, John L. Sullivan, Katherine Luzuriaga, and Keith Mansfield Pneumonitis and Multi-Organ System Disease in Common Marmosets (Callithrix jacchus) Infected with the Severe Acute Respiratory Syndrome-Associated Coronavirus Am J Pathol 2005 167: 455-463. [Abstract] [Full Text] [PDF]   Margaret G. Petroff, Elza Kharatyan, Donald S. Torry, and Lesya Holets The Immunomodulatory Proteins B7-DC, B7-H2, and B7-H3 Are Differentially Expressed across Gestation in the Human Placenta Am J Pathol 2005 167: 465-473. [Abstract] [Full Text] [PDF]

Matrix Pathobiology: Michael D. Amatangelo, Daniel E. Bassi, Andrés J.P. Klein-Szanto, and Edna Cukierman Stroma-Derived Three-Dimensional Matrices Are Necessary and Sufficient to Promote Desmoplastic Differentiation of Normal Fibroblasts Am J Pathol 2005 167: 475-488. [Abstract] [Full Text] [PDF]   Nick Di Girolamo, Minas Coroneo, and Denis Wakefield Epidermal Growth Factor Receptor Signaling Is Partially Responsible for the Increased Matrix Metalloproteinase-1 Expression in Ocular Epithelial Cells after UVB Radiation Am J Pathol 2005 167: 489-503. [Abstract] [Full Text] [PDF]

Neurobiology: Jianting Miao, Feng Xu, Judianne Davis, Irene Otte-Höller, Marcel M. Verbeek, and William E. Van Nostrand Cerebral Microvascular Amyloid ß Protein Deposition Induces Vascular Degeneration and Neuroinflammation in Transgenic Mice Expressing Human Vasculotropic Mutant Amyloid ß Precursor Protein Am J Pathol 2005 167: 505-515. [Abstract] [Full Text] [PDF]   Pietro Fratta, W. King Engel, Janis McFerrin, Kelvin J.A. Davies, Sharon W. Lin, and Valerie Askanas Proteasome Inhibition and Aggresome Formation in Sporadic Inclusion-Body Myositis and in Amyloid-ß Precursor Protein-Overexpressing Cultured Human Muscle Fibers Am J Pathol 2005 167: 517-526. [Abstract] [Full Text] [PDF]   Samir Kumar-Singh, Daniel Pirici, Eileen McGowan, Sally Serneels, Chantal Ceuterick, John Hardy, Karen Duff, Dennis Dickson, and Christine Van Broeckhoven Dense-Core Plaques in Tg2576 and PSAPP Mouse Models of Alzheimer’s Disease Are Centered on Vessel Walls Am J Pathol 2005 167: 527-543. [Abstract] [Full Text] [PDF]   Emma East, David Baker, Gareth Pryce, H. Roger Lijnen, M. Louise Cuzner, and Djordje Gveric A Role for the Plasminogen Activator System in Inflammation and Neurodegeneration in the Central Nervous System during Experimental Allergic Encephalomyelitis Am J Pathol 2005 167: 545-554. [Abstract] [Full Text] [PDF]

Stem Cells, Tissue Engineering and Hematopoietic Elements: Amar Deep Sharma, Tobias Cantz, Rudolf Richter, Klaus Eckert, Reinhard Henschler, Ludwig Wilkens, Andrea Jochheim-Richter, Lubomir Arseniev, and Michael Ott Human Cord Blood Stem Cells Generate Human Cytokeratin 18-Negative Hepatocyte-Like Cells in Injured Mouse Liver Am J Pathol 2005 167: 555-564. [Abstract] [Full Text] [PDF]

Tumorigenesis and Neoplastic Progression: Mitsutoshi Nakada, Jared A. Niska, Nhan L. Tran, Wendy S. McDonough, and Michael E. Berens EphB2/R-Ras Signaling Regulates Glioma Cell Adhesion, Growth, and Invasion Am J Pathol 2005 167: 565-576. [Abstract] [Full Text] [PDF]   Adam H. Johnson, Henry F. Frierson, Alexander Zaika, Steven M. Powell, James Roche, Sheila Crowe, Christopher A. Moskaluk, and Wa’el El-Rifai Expression of Tight-Junction Protein Claudin-7 Is an Early Event in Gastric Tumorigenesis Am J Pathol 2005 167: 577-584. [Abstract] [Full Text] [PDF]   Youping Sun, Luigi Strizzi, Ahmed Raafat, Morihisa Hirota, Caterina Bianco, Lionel Feigenbaum, Nicholas Kenney, Christian Wechselberger, Robert Callahan, and David S. Salomon Overexpression of Human Cripto-1 in Transgenic Mice Delays Mammary Gland Development and Differentiation and Induces Mammary Tumorigenesis Am J Pathol 2005 167: 585-597. [Abstract] [Full Text] [PDF]

Vascular Biology, Atherosclerosis and Endothelium Biology: Mohamed Al-Shabrawey, Manuela Bartoli, Azza B. El-Remessy, Daniel H. Platt, Sue Matragoon, M. Ali Behzadian, Robert W. Caldwell, and Ruth B. Caldwell Inhibition of NAD(P)H Oxidase Activity Blocks Vascular Endothelial Growth Factor Overexpression and Neovascularization during Ischemic Retinopathy Am J Pathol 2005 167: 599-607. [Abstract] [Full Text] [PDF]   Rob J. Dekker, Johannes V. van Thienen, Jakub Rohlena, Saskia C. de Jager, Yvonne W. Elderkamp, Jurgen Seppen, Carlie J.M. de Vries, Erik A.L. Biessen, Theo J.C. van Berkel, Hans Pannekoek, and Anton J.G. Horrevoets Endothelial KLF2 Links Local Arterial Shear Stress Levels to the Expression of Vascular Tone-Regulating Genes Am J Pathol 2005 167: 609-618. [Abstract] [Full Text] [PDF]   Sheri E. Kelemen and Michael V. Autieri Expression of Allograft Inflammatory Factor-1 in T Lymphocytes: A Role in T-Lymphocyte Activation and Proliferative Arteriopathies Am J Pathol 2005 167: 619-626. [Abstract] [Full Text] [PDF]

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