Reviews: James M. Musser and Frank R. DeLeo Toward a Genome-Wide Systems Biology Analysis of Host-Pathogen Interactions in Group A Streptococcus Am J Pathol 2005 167: 1461-1472. [Abstract] [Full Text] [PDF]

Commentaries: John J. Shacka and Kevin A. Roth Cathepsin Deficiency as a Model for Neuronal Ceroid Lipofuscinoses Am J Pathol 2005 167: 1473-1476. [Full Text] [PDF]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Giuliano Ciarimboli, Thomas Ludwig, Detlef Lang, Hermann Pavenstädt, Hermann Koepsell, Hans-Jürgen Piechota, Jörg Haier, Ulrich Jaehde, Jochen Zisowsky, and Eberhard Schlatter Cisplatin Nephrotoxicity Is Critically Mediated via the Human Organic Cation Transporter 2 Am J Pathol 2005 167: 1477-1484. [Abstract] [Full Text] [PDF]   Francois Huaux, M. Gharaee-Kermani, Tianju Liu, Valérie Morel, Bridget McGarry, Matt Ullenbruch, Steven L. Kunkel, Jun Wang, Zhou Xing, and Sem H. Phan Role of Eotaxin-1 (CCL11) and CC Chemokine Receptor 3 (CCR3) in Bleomycin-Induced Lung Injury and Fibrosis Am J Pathol 2005 167: 1485-1496. [Abstract] [Full Text] [PDF]   Laure Favot, Susan M. Hall, Sheila G. Haworth, and Paul R. Kemp Cytoplasmic YY1 Is Associated with Increased Smooth Muscle-Specific Gene Expression: Implications for Neonatal Pulmonary Hypertension Am J Pathol 2005 167: 1497-1509. [Abstract] [Full Text] [PDF]   Guohong Li, John M. Sanders, Elizabeth T. Phan, Klaus Ley, and Ian J. Sarembock Arterial Macrophages and Regenerating Endothelial Cells Express P-Selectin in Atherosclerosis-Prone Apolipoprotein E-Deficient Mice Am J Pathol 2005 167: 1511-1518. [Abstract] [Full Text] [PDF]

Cell Injury, Repair, Aging and Apoptosis: Yunan Zhao, Tadamichi Shimizu, Jun Nishihira, Yoshikazu Koyama, Toshihiro Kushibiki, Ayumi Honda, Hirokazu Watanabe, Riichiro Abe, Yasuhiko Tabata, and Hiroshi Shimizu Tissue Regeneration Using Macrophage Migration Inhibitory Factor-Impregnated Gelatin Microbeads in Cutaneous Wounds Am J Pathol 2005 167: 1519-1529. [Abstract] [Full Text] [PDF]   Juan Arredondo, Alexander I. Chernyavsky, Ali Karaouni, and Sergei A. Grando Novel Mechanisms of Target Cell Death and Survival and of Therapeutic Action of IVIg in Pemphigus Am J Pathol 2005 167: 1531-1544. [Abstract] [Full Text] [PDF]   Mario Perl, Chun-Shiang Chung, Joanne Lomas-Neira, Tina-Marie Rachel, Walter L. Biffl, William G. Cioffi, and Alfred Ayala Silencing of Fas, but Not Caspase-8, in Lung Epithelial Cells Ameliorates Pulmonary Apoptosis, Inflammation, and Neutrophil Influx after Hemorrhagic Shock and Sepsis Am J Pathol 2005 167: 1545-1559. [Abstract] [Full Text] [PDF]   Matthew J. Hardman, Alexander Waite, Leo Zeef, Matthew Burow, Toshinori Nakayama, and Gillian S. Ashcroft Macrophage Migration Inhibitory Factor: A Central Regulator of Wound Healing Am J Pathol 2005 167: 1561-1574. [Abstract] [Full Text] [PDF] Supplemental Material   David J. Geer, Daniel D. Swartz, and Stelios T. Andreadis Biomimetic Delivery of Keratinocyte Growth Factor upon Cellular Demand for Accelerated Wound Healing in Vitro and in Vivo Am J Pathol 2005 167: 1575-1586. [Abstract] [Full Text] [PDF]

Epithelial and Mesenchymal Cell Biology: Kathryn L. Howe, Colin Reardon, Arthur Wang, Aisha Nazli, and Derek M. McKay Transforming Growth Factor-ß Regulation of Epithelial Tight Junction Proteins Enhances Barrier Function and Blocks Enterohemorrhagic Escherichia coli O157:H7-Induced Increased Permeability Am J Pathol 2005 167: 1587-1597. [Abstract] [Full Text] [PDF]

Immunopathology and Infectious Disease: Paola Secchiero, Elisa Barbarotto, Arianna Gonelli, Mario Tiribelli, Carlotta Zerbinati, Claudio Celeghini, Claudio Agostinelli, Stefano A. Pileri, and Giorgio Zauli Potential Pathogenetic Implications of Cyclooxygenase-2 Overexpression in B Chronic Lymphoid Leukemia Cells Am J Pathol 2005 167: 1599-1607. [Abstract] [Full Text] [PDF]   Simona Ozden, Vincent Mouly, Marie-Christine Prevost, Antoine Gessain, Gillian Butler-Browne, and Pierre-Emmanuel Ceccaldi Muscle Wasting Induced by HTLV-1 Tax-1 Protein: An in Vitro and in Vivo Study Am J Pathol 2005 167: 1609-1619. [Abstract] [Full Text] [PDF]   Romy Fischer, Jerry R. McGhee, Huong Lan Vu, T. Prescott Atkinson, Raymond J. Jackson, Daniel Tomé, and Prosper N. Boyaka Oral and Nasal Sensitization Promote Distinct Immune Responses and Lung Reactivity in a Mouse Model of Peanut Allergy Am J Pathol 2005 167: 1621-1630. [Abstract] [Full Text] [PDF]   Ikuo Tsunoda, Jane E. Libbey, Li-Qing Kuang, Emily Jane Terry, and Robert S. Fujinami Massive Apoptosis in Lymphoid Organs in Animal Models for Primary and Secondary Progressive Multiple Sclerosis Am J Pathol 2005 167: 1631-1646. [Abstract] [Full Text] [PDF]   Claudine S. Bonder, M. Ursula Norman, Tara MacRae, Paul R. Mangan, Casey T. Weaver, Daniel C. Bullard, Donna-Marie McCafferty, and Paul Kubes P-Selectin Can Support Both Th1 and Th2 Lymphocyte Rolling in the Intestinal Microvasculature Am J Pathol 2005 167: 1647-1660. [Abstract] [Full Text] [PDF]   Paul R. Mangan, Darrell O’Quinn, Laurie Harrington, Claudine S. Bonder, Paul Kubes, Dennis F. Kucik, Daniel C. Bullard, and Casey T. Weaver Both Th1 and Th2 Cells Require P-Selectin Glycoprotein Ligand-1 for Optimal Rolling on Inflamed Endothelium Am J Pathol 2005 167: 1661-1675. [Abstract] [Full Text] [PDF] Supplemental Material   David Torres, Laure Janot, Valerie F.J. Quesniaux, Sergei I. Grivennikov, Isabelle Maillet, Jonathon D. Sedgwick, Bernhard Ryffel, and Francois Erard Membrane Tumor Necrosis Factor Confers Partial Protection to Listeria Infection Am J Pathol 2005 167: 1677-1687. [Abstract] [Full Text] [PDF]

Matrix Pathobiology: Anna Caciotti, Maria Alice Donati, Tiziana Bardelli, Alessandra d’Azzo, Graziella Massai, Luciana Luciani, Enrico Zammarchi, and Amelia Morrone Primary and Secondary Elastin-Binding Protein Defect Leads to Impaired Elastogenesis in Fibroblasts from GM1-Gangliosidosis Patients Am J Pathol 2005 167: 1689-1698. [Abstract] [Full Text] [PDF]   Yunliang Chen, Xu Shi-wen, Jonathan van Beek, Laura Kennedy, Marilyn McLeod, Elisabetta A. Renzoni, George Bou-Gharios, Sarah Wilcox-Adelman, Paul F. Goetinck, Mark Eastwood, Carol M. Black, David J. Abraham, and Andrew Leask Matrix Contraction by Dermal Fibroblasts Requires Transforming Growth Factor-ß/Activin-Linked Kinase 5, Heparan Sulfate-Containing Proteoglycans, and MEK/ERK: Insights into Pathological Scarring in Chronic Fibrotic Disease Am J Pathol 2005 167: 1699-1711. [Abstract] [Full Text] [PDF]

Neurobiology: Masato Koike, Masahiro Shibata, Satoshi Waguri, Kentaro Yoshimura, Isei Tanida, Eiki Kominami, Takahiro Gotow, Christoph Peters, Kurt von Figura, Noboru Mizushima, Paul Saftig, and Yasuo Uchiyama Participation of Autophagy in Storage of Lysosomes in Neurons from Mouse Models of Neuronal Ceroid-Lipofuscinoses (Batten Disease) Am J Pathol 2005 167: 1713-1728. [Abstract] [Full Text] [PDF] Supplemental Material   Manuela Pastore, Steven S. Chin, Karen L. Bell, Zhiqian Dong, Qiwei Yang, Lizhu Yang, Jue Yuan, Shu G. Chen, Pierluigi Gambetti, and Wen-Quan Zou Creutzfeldt-Jakob Disease (CJD) with a Mutation at Codon 148 of Prion Protein Gene: Relationship with Sporadic CJD Am J Pathol 2005 167: 1729-1738. [Abstract] [Full Text] [PDF]

Tumorigenesis and Neoplastic Progression: Neveen Said and Kouros Motamed Absence of Host-Secreted Protein Acidic and Rich in Cysteine (SPARC) Augments Peritoneal Ovarian Carcinomatosis Am J Pathol 2005 167: 1739-1752. [Abstract] [Full Text] [PDF] Supplemental Material   Kelly E. Fathers, Courtney M. Stone, Kanwal Minhas, Jason J.A. Marriott, Janice D. Greenwood, Daniel J. Dumont, and Brenda L. Coomber Heterogeneity of Tie2 Expression in Tumor Microcirculation: Influence of Cancer Type, Implantation Site, and Response to Therapy Am J Pathol 2005 167: 1753-1762. [Abstract] [Full Text] [PDF]   Robert S. Stearman, Lori Dwyer-Nield, Laura Zerbe, Stacy A. Blaine, Zeng Chan, Paul A. Bunn, Jr., Gary L. Johnson, Fred R. Hirsch, Daniel T. Merrick, Wilbur A. Franklin, Anna E. Baron, Robert L. Keith, Raphael A. Nemenoff, Alvin M. Malkinson, and Mark W. Geraci Analysis of Orthologous Gene Expression between Human Pulmonary Adenocarcinoma and a Carcinogen-Induced Murine Model Am J Pathol 2005 167: 1763-1775. [Abstract] [Full Text] [PDF] Supplemental Material

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