Commentaries: Carlos Sonnenschein and Ana M. Soto Carcinogenesis and Metastasis Now in the Third Dimension—What’s in It for Pathologists? Am J Pathol 2006 168: 363-366. [Full Text] [PDF]   Debabrata Mukhopadhyay The Tumor Suppressor von Hippel-Lindau Gene Product and Metastasis: New Thoughts on an Old Molecule Am J Pathol 2006 168: 367-369. [Full Text] [PDF]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Markus Wörnle, Holger Schmid, Bernhard Banas, Monika Merkle, Anna Henger, Maximilian Roeder, Simone Blattner, Elisabeth Bock, Matthias Kretzler, Hermann-Josef Gröne, and Detlef Schlöndorff Novel Role of Toll-Like Receptor 3 in Hepatitis C-Associated Glomerulonephritis Am J Pathol 2006 168: 370-385. [Abstract] [Full Text] [PDF]   Shusaku Miyata, Genzou Takemura, Yukinori Kawase, Yiwen Li, Hideshi Okada, Rumi Maruyama, Hiroaki Ushikoshi, Masayasu Esaki, Hiromitsu Kanamori, Longhu Li, Yu Misao, Asaki Tezuka, Teruhiko Toyo-Oka, Shinya Minatoguchi, Takako Fujiwara, and Hisayoshi Fujiwara Autophagic Cardiomyocyte Death in Cardiomyopathic Hamsters and Its Prevention by Granulocyte Colony-Stimulating Factor Am J Pathol 2006 168: 386-397. [Abstract] [Full Text] [PDF]

Gastrointestinal, Hepatobiliary and Pancreatic Pathology: Marco Marzioni, Heather Francis, Antonio Benedetti, Yoshiyuki Ueno, Giammarco Fava, Juliet Venter, Ramona Reichenbach, Maria Grazia Mancino, Ryun Summers, Gianfranco Alpini, and Shannon Glaser Ca2+-Dependent Cytoprotective Effects of Ursodeoxycholic and Tauroursodeoxycholic Acid on the Biliary Epithelium in a Rat Model of Cholestasis and Loss of Bile Ducts Am J Pathol 2006 168: 398-409. [Abstract] [Full Text] [PDF]   Peter Fickert, Andrea Fuchsbichler, Hanns-Ulrich Marschall, Martin Wagner, Gernot Zollner, Robert Krause, Kurt Zatloukal, Hartmut Jaeschke, Helmut Denk, and Michael Trauner Lithocholic Acid Feeding Induces Segmental Bile Duct Obstruction and Destructive Cholangitis in Mice Am J Pathol 2006 168: 410-422. [Abstract] [Full Text] [PDF]   Dominik Huster, Milton J. Finegold, Clinton T. Morgan, Jason L. Burkhead, Randal Nixon, Scott M. Vanderwerf, Conrad T. Gilliam, and Svetlana Lutsenko Consequences of Copper Accumulation in the Livers of the Atp7b–/– (Wilson Disease Gene) Knockout Mice Am J Pathol 2006 168: 423-434. [Abstract] [Full Text] [PDF]

Growth Factors, Cytokines, Cell Cycle Molecules: Jaap G. Neels, Manjula Pandey, Gökhan S. Hotamisligil, and Fahumiya Samad Autoamplification of Tumor Necrosis Factor-: A Potential Mechanism for the Maintenance of Elevated Tumor Necrosis Factor- in Male but Not Female Obese Mice Am J Pathol 2006 168: 435-444. [Abstract] [Full Text] [PDF]   Charles J. Lockwood, Paul Matta, Graciela Krikun, Louise A. Koopman, Rachel Masch, Paolo Toti, Felice Arcuri, Se-Te Joseph Huang, Edmund F. Funai, and Frederick Schatz Regulation of Monocyte Chemoattractant Protein-1 Expression by Tumor Necrosis Factor- and Interleukin-1ß in First Trimester Human Decidual Cells: Implications for Preeclampsia Am J Pathol 2006 168: 445-452. [Abstract] [Full Text] [PDF]

Immunopathology and Infectious Disease: Gregory Gautier, Blandine de Saint-Vis, Brigitte Sénéchal, Jean-Jacques Pin, Elizabeth E.M. Bates, Christophe Caux, Frédéric Geissmann, and Pierre Garrone The Class 6 Semaphorin SEMA6A Is Induced by Interferon- and Defines an Activation Status of Langerhans Cells Observed in Pathological Situations Am J Pathol 2006 168: 453-465. [Abstract] [Full Text] [PDF]   Steve D. Swain, Nicole N. Meissner, and Allen G. Harmsen CD8 T Cells Modulate CD4 T-Cell and Eosinophil-Mediated Pulmonary Pathology in Pneumocystis Pneumonia in B-Cell-Deficient Mice Am J Pathol 2006 168: 466-475. [Abstract] [Full Text] [PDF]   Yulia Vugmeyster, Dhaya Seshasayee, Wesley Chang, Anahid Storn, Kathy Howell, Susan Sa, Tenea Nelson, Flavius Martin, Iqbal Grewal, Ellen Gilkerson, Ben Wu, Jeff Thompson, Barbara N. Ehrenfels, Song Ren, An Song, Thomas R. Gelzleichter, and Dimitry M. Danilenko A Soluble BAFF Antagonist, BR3-Fc, Decreases Peripheral Blood B Cells and Lymphoid Tissue Marginal Zone and Follicular B Cells in Cynomolgus Monkeys Am J Pathol 2006 168: 476-489. [Abstract] [Full Text] [PDF]

Matrix Pathobiology: Jeoung Soo Lee, Dina M. Basalyga, Agneta Simionescu, Jason C. Isenburg, Dan T. Simionescu, and Narendra R. Vyavahare Elastin Calcification in the Rat Subdermal Model Is Accompanied by Up-Regulation of Degradative and Osteogenic Cellular Responses Am J Pathol 2006 168: 490-498. [Abstract] [Full Text] [PDF]   Yoshihide Asano, Hironobu Ihn, Kenichi Yamane, Masatoshi Jinnin, and Kunihiko Tamaki Increased Expression of Integrin vß5 Induces the Myofibroblastic Differentiation of Dermal Fibroblasts Am J Pathol 2006 168: 499-510. [Abstract] [Full Text] [PDF]

Metabolic, Endocrine and Genitourinary Pathobiology: Padma Murthi, Vicki Doherty, Joanne Said, Susan Donath, Shaun P. Brennecke, and Bill Kalionis Homeobox Gene HLX1Expression Is Decreased in Idiopathic Human Fetal Growth Restriction Am J Pathol 2006 168: 511-518. [Abstract] [Full Text] [PDF]   Xiaoqing Liu, Yun Zhao, Basil Pawlyk, Margot Damaser, and Tiansen Li Failure of Elastic Fiber Homeostasis Leads to Pelvic Floor Disorders Am J Pathol 2006 168: 519-528. [Abstract] [Full Text] [PDF]

Stem Cells, Tissue Engineering and Hematopoietic Elements: Mirela Anghelina, Padma Krishnan, Leni Moldovan, and Nicanor I. Moldovan Monocytes/Macrophages Cooperate with Progenitor Cells during Neovascularization and Tissue Repair: Conversion of Cell Columns into Fibrovascular Bundles Am J Pathol 2006 168: 529-541. [Abstract] [Full Text] [PDF] Supplemental Material   Mahesh H. Mankani, Sergei A. Kuznetsov, Brian Shannon, Ravi K. Nalla, Robert O. Ritchie, Yixian Qin, and Pamela Gehron Robey Canine Cranial Reconstruction Using Autologous Bone Marrow Stromal Cells Am J Pathol 2006 168: 542-550. [Abstract] [Full Text] [PDF]

Tumorigenesis and Neoplastic Progression: Tajneen Natasha, Misty Kuhn, Owen Kelly, and Susan R. Rittling Override of the Osteoclast Defect in Osteopontin-Deficient Mice by Metastatic Tumor Growth in the Bone Am J Pathol 2006 168: 551-561. [Abstract] [Full Text] [PDF]   Benjamin Chaigne-Delalande, Lynda Deuve, Edith Reuzeau, Caroline Basoni, David Lafarge, Christine Varon, Florence Tatin, Guerric Anies, Richard Garand, Ijsbrand Kramer, and Elisabeth Génot RhoGTPases and p53 Are Involved in the Morphological Appearance and Interferon- Response of Hairy Cells Am J Pathol 2006 168: 562-573. [Abstract] [Full Text] [PDF]   Eijiro Nakamura, Paula Abreu-e-Lima, Yasuo Awakura, Takahiro Inoue, Toshiyuki Kamoto, Osamu Ogawa, Hirokazu Kotani, Toshiaki Manabe, Guo-Jun Zhang, Keiichi Kondo, Vania Nosé, and William G. Kaelin, Jr Clusterin Is a Secreted Marker for a Hypoxia-Inducible Factor-Independent Function of the von Hippel-Lindau Tumor Suppressor Protein Am J Pathol 2006 168: 574-584. [Abstract] [Full Text] [PDF]   Zhaocheng Zhang, Raj S. Mitra, Bradley S. Henson, Nabanita S. Datta, Laurie K. McCauley, Pawan Kumar, Julia S.-J. Lee, Thomas E. Carey, and Nisha J. D’Silva Rap1GAP Inhibits Tumor Growth in Oropharyngeal Squamous Cell Carcinoma Am J Pathol 2006 168: 585-596. [Abstract] [Full Text] [PDF]   Guoying Yu, George C. Tseng, Yan Ping Yu, Tim Gavel, Joel Nelson, Alan Wells, George Michalopoulos, Demetrius Kokkinakis, and Jian-Hua Luo CSR1 Suppresses Tumor Growth and Metastasis of Prostate Cancer Am J Pathol 2006 168: 597-607. [Abstract] [Full Text] [PDF]   Shauntae M. McDaniel, Kristen K. Rumer, Sandra L. Biroc, Richard P. Metz, Meenakshi Singh, Weston Porter, and Pepper Schedin Remodeling of the Mammary Microenvironment after Lactation Promotes Breast Tumor Cell Metastasis Am J Pathol 2006 168: 608-620. [Abstract] [Full Text] [PDF]

Vascular Biology, Atherosclerosis and Endothelium Biology: Matthew R. Ritter, John Reinisch, Sheila Fallon Friedlander, and Martin Friedlander Myeloid Cells in Infantile Hemangioma Am J Pathol 2006 168: 621-628. [Abstract] [Full Text] [PDF]   Anna Csiszar, Mansoor Ahmad, Kira E. Smith, Nazar Labinskyy, Qun Gao, Gabor Kaley, John G. Edwards, Michael S. Wolin, and Zoltan Ungvari Bone Morphogenetic Protein-2 Induces Proinflammatory Endothelial Phenotype Am J Pathol 2006 168: 629-638. [Abstract] [Full Text] [PDF]   Arindel S.R. Maharaj, Magali Saint-Geniez, Angel E. Maldonado, and Patricia A. D’Amore Vascular Endothelial Growth Factor Localization in the Adult Am J Pathol 2006 168: 639-648. [Abstract] [Full Text] [PDF]   Fiona Anne Stewart, Sylvia Heeneman, Johannes te Poele, Jacqueline Kruse, Nicola S. Russell, Marion Gijbels, and Mat Daemen Ionizing Radiation Accelerates the Development of Atherosclerotic Lesions in ApoE–/– Mice and Predisposes to an Inflammatory Plaque Phenotype Prone to Hemorrhage Am J Pathol 2006 168: 649-658. [Abstract] [Full Text] [PDF]   Maria G. Frid, Jacqueline A. Brunetti, Danielle L. Burke, Todd C. Carpenter, Neil J. Davie, John T. Reeves, Mark T. Roedersheimer, Nico van Rooijen, and Kurt R. Stenmark Hypoxia-Induced Pulmonary Vascular Remodeling Requires Recruitment of Circulating Mesenchymal Precursors of a Monocyte/Macrophage Lineage Am J Pathol 2006 168: 659-669. [Abstract] [Full Text] [PDF]   Detlev Roth, Michael Piekarek, Mats Paulsson, Hildegard Christ, Thomas Krieg, Wilhelm Bloch, Jeffrey M. Davidson, and Sabine A. Eming Plasmin Modulates Vascular Endothelial Growth Factor-A-Mediated Angiogenesis during Wound Repair Am J Pathol 2006 168: 670-684. [Abstract] [Full Text] [PDF]   Xian Wu Cheng, Masafumi Kuzuya, Kae Nakamura, Qun Di, Zexuan Liu, Takeshi Sasaki, Shigeru Kanda, Hai Jin, Guo-Ping Shi, Toyoaki Murohara, Mitsuhiro Yokota, and Akihisa Iguchi Localization of Cysteine Protease, Cathepsin S, to the Surface of Vascular Smooth Muscle Cells by Association with Integrin ß3 Am J Pathol 2006 168: 685-694. [Abstract] [Full Text] [PDF]   Sei-ichiro Tsuchihashi, Bibo Ke, Fady Kaldas, Evelyn Flynn, Ronald W. Busuttil, David M. Briscoe, and Jerzy W. Kupiec-Weglinski Vascular Endothelial Growth Factor Antagonist Modulates Leukocyte Trafficking and Protects Mouse Livers against Ischemia/Reperfusion Injury Am J Pathol 2006 168: 695-705. [Abstract] [Full Text] [PDF]   Valentina Fonsato, Stefano Buttiglieri, Maria Chiara Deregibus, Valeria Puntorieri, Benedetta Bussolati, and Giovanni Camussi Expression of Pax2 in Human Renal Tumor-Derived Endothelial Cells Sustains Apoptosis Resistance and Angiogenesis Am J Pathol 2006 168: 706-713. [Abstract] [Full Text] [PDF]

Correction: Corrections Am J Pathol 2006 168: 714. [Full Text] [PDF]

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