Am J Pathol JNCI
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Cover Figure


On the Cover: Keratocysts that develop in K5-Gli2 transgenic mice exhibit many of the same gross, microscopic, biochemical, and molecular features seen in odontogenic keratocysts arising in humans, including deregulated activation of the Hedgehog signaling pathway in epithelial cells comprising the cyst wall. Shown are two small, intact keratinizing jaw cysts near molar tooth roots of K5-Gli2 mice. (See page 806)
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Copyright © 2007 by the American Society for Investigative Pathology.