Reviews: Stephanie Cowey and Robert W. Hardy The Metabolic Syndrome: A High-Risk State for Cancer? Am J Pathol 2006 169: 1505-1522. ; doi: 10.2353/ajpath.2006.051090 [Abstract] [Full Text] [PDF]

Commentaries: Beatrice Knudsen Migrating with Myosin VI Am J Pathol 2006 169: 1523-1526. ; doi: 10.2353/ajpath.2006.060712 [Full Text] [PDF]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Jinhua Li, Naomi Vittoria Campanale, Rong Jiao Liang, James Antony Deane, John Frederick Bertram, and Sharon Denise Ricardo Inhibition of p38 Mitogen-Activated Protein Kinase and Transforming Growth Factor-ß1/Smad Signaling Pathways Modulates the Development of Fibrosis in Adriamycin-Induced Nephropathy Am J Pathol 2006 169: 1527-1540. ; doi: 10.2353/ajpath.2006.060169 [Abstract] [Full Text] [PDF]   Robin D. Clugston, Jürgen Klattig, Chistoph Englert, Margaret Clagett-Dame, Jelena Martinovic, Alexandra Benachi, and John J. Greer Teratogen-Induced, Dietary and Genetic Models of Congenital Diaphragmatic Hernia Share a Common Mechanism of Pathogenesis Am J Pathol 2006 169: 1541-1549. ; doi: 10.2353/ajpath.2006.060445 [Abstract] [Full Text] [PDF]   Hanako Sato, Takuya Yazawa, Takehisa Suzuki, Hiroaki Shimoyamada, Koji Okudela, Masaichi Ikeda, Kenji Hamada, Hisafumi Yamada-Okabe, Masayuki Yao, Yoshinobu Kubota, Takashi Takahashi, Hiroshi Kamma, and Hitoshi Kitamura Growth Regulation via Insulin-Like Growth Factor Binding Protein-4 and -2 in Association with Mutant K-ras in Lung Epithelia Am J Pathol 2006 169: 1550-1566. ; doi: 10.2353/ajpath.2006.051068 [Abstract] [Full Text] [PDF]   Jimena Cuenca, Paloma Martín-Sanz, Alberto M. Álvarez-Barrientos, Lisardo Boscá, and Nora Goren Infiltration of Inflammatory Cells Plays an Important Role in Matrix Metalloproteinase Expression and Activation in the Heart during Sepsis Am J Pathol 2006 169: 1567-1576. ; doi: 10.2353/ajpath.2006.060109 [Abstract] [Full Text] [PDF]   Hirokazu Okada, Tsutomu Inoue, Tomohiro Kikuta, Yusuke Watanabe, Yoshihiko Kanno, Shinichi Ban, Takeshi Sugaya, Masatsugu Horiuchi, and Hiromichi Suzuki A Possible Anti-Inflammatory Role of Angiotensin II Type 2 Receptor in Immune-Mediated Glomerulonephritis during Type 1 Receptor Blockade Am J Pathol 2006 169: 1577-1589. ; doi: 10.2353/ajpath.2006.060178 [Abstract] [Full Text] [PDF]

Cell Injury, Repair, Aging and Apoptosis: Zhijie Li, Alan R. Burns, and C. Wayne Smith Lymphocyte Function-Associated Antigen-1-Dependent Inhibition of Corneal Wound Healing Am J Pathol 2006 169: 1590-1600. ; doi: 10.2353/ajpath.2006.060415 [Abstract] [Full Text] [PDF]   Hae-June Lee, Yoon-Jin Lee, Hee-Chung Kwon, Sangwoo Bae, Sung-Ho Kim, Jung-Joon Min, Chul-Koo Cho, and Yun-Sil Lee Radioprotective Effect of Heat Shock Protein 25 on Submandibular Glands of Rats Am J Pathol 2006 169: 1601-1611. ; doi: 10.2353/ajpath.2006.060327 [Abstract] [Full Text] [PDF]   Francesca Seta, Lars Bellner, Rita Rezzani, Raymond F. Regan, Michael W. Dunn, Nader G. Abraham, Karsten Gronert, and Michal Laniado-Schwartzman Heme Oxygenase-2 Is a Critical Determinant for Execution of an Acute Inflammatory and Reparative Response Am J Pathol 2006 169: 1612-1623. ; doi: 10.2353/ajpath.2006.060555 [Abstract] [Full Text] [PDF]

Epithelial and Mesenchymal Cell Biology: François Maquerlot, Stephane Galiacy, Michel Malo, Christophe Guignabert, Daniel A. Lawrence, Maria-Pia d’Ortho, and Georgia Barlovatz-Meimon Dual Role for Plasminogen Activator Inhibitor Type 1 as Soluble and as Matricellular Regulator of Epithelial Alveolar Cell Wound Healing Am J Pathol 2006 169: 1624-1632. ; doi: 10.2353/ajpath.2006.051053 [Abstract] [Full Text] [PDF]   Hidekata Yasuoka, Zhihong Zhou, Joseph M. Pilewski, Tim D. Oury, Augustine M.K. Choi, and Carol A. Feghali-Bostwick Insulin-Like Growth Factor-Binding Protein-5 Induces Pulmonary Fibrosis and Triggers Mononuclear Cellular Infiltration Am J Pathol 2006 169: 1633-1642. ; doi: 10.2353/ajpath.2006.060501 [Abstract] [Full Text] [PDF]   Mami Mihara, Yukinari Yoshida, Tetsuya Tsukamoto, Ken-ichi Inada, Yukihiro Nakanishi, Yukiko Yagi, Kohzoh Imai, Takashi Sugimura, Masae Tatematsu, and Toshikazu Ushijima Methylation of Multiple Genes in Gastric Glands with Intestinal Metaplasia: A Disorder with Polyclonal Origins Am J Pathol 2006 169: 1643-1651. ; doi: 10.2353/ajpath.2006.060552 [Abstract] [Full Text] [PDF]   Prashiela Manga, David Sheyn, Fan Yang, Rangaprasad Sarangarajan, and Raymond E. Boissy A Role for Tyrosinase-Related Protein 1 in 4-tert-Butylphenol-Induced Toxicity in Melanocytes: Implications for Vitiligo Am J Pathol 2006 169: 1652-1662. ; doi: 10.2353/ajpath.2006.050769 [Abstract] [Full Text] [PDF]

Immunopathology and Infectious Disease: Xu Wang, Steven D. Douglas, Jin-Song Peng, Dun-Jin Zhou, Qi Wan, and Wen-Zhe Ho An in Vitro Model of Morphine Withdrawal Manifests the Enhancing Effect on Human Immunodeficiency Virus Infection of Human T Lymphocytes through the Induction of Substance P Am J Pathol 2006 169: 1663-1670. ; doi: 10.2353/ajpath.2006.060358 [Abstract] [Full Text] [PDF]   Lizette Visser, Marie-José Melief, Debby van Riel, Marjan van Meurs, Ella A. Sick, Seiichi Inamura, Jeffrey J. Bajramovic, Sandra Amor, Rogier Q. Hintzen, Leonie A. Boven, Bert A. ’t Hart, and Jon D. Laman Phagocytes Containing a Disease-Promoting Toll-Like Receptor/Nod Ligand Are Present in the Brain during Demyelinating Disease in Primates Am J Pathol 2006 169: 1671-1685. ; doi: 10.2353/ajpath.2006.060143 [Abstract] [Full Text] [PDF]   Matam Vijay-Kumar, Huixia Wu, Rheinallt Jones, George Grant, Brian Babbin, Timothy P. King, Denise Kelly, Andrew T. Gewirtz, and Andrew S. Neish Flagellin Suppresses Epithelial Apoptosis and Limits Disease during Enteric Infection Am J Pathol 2006 169: 1686-1700. ; doi: 10.2353/ajpath.2006.060345 [Abstract] [Full Text] [PDF] Supplemental Material   Mosiuoa Leeto, De’Broski R. Herbert, Reece Marillier, Anita Schwegmann, Lizette Fick, and Frank Brombacher TH1-Dominant Granulomatous Pathology Does Not Inhibit Fibrosis or Cause Lethality during Murine Schistosomiasis Am J Pathol 2006 169: 1701-1712. ; doi: 10.2353/ajpath.2006.060346 [Abstract] [Full Text] [PDF]   Maki Kakurai, Rossella Monteforte, Hajime Suto, Mindy Tsai, Susumu Nakae, and Stephen J. Galli Mast Cell-Derived Tumor Necrosis Factor Can Promote Nerve Fiber Elongation in the Skin during Contact Hypersensitivity in Mice Am J Pathol 2006 169: 1713-1721. ; doi: 10.2353/ajpath.2006.060602 [Abstract] [Full Text] [PDF] Supplemental Material

Metabolic, Endocrine and Genitourinary Pathobiology: Satoshi Sekiguchi, Jungkee Kwon, Etsuko Yoshida, Hiroko Hamasaki, Shizuko Ichinose, Makoto Hideshima, Mutsuki Kuraoka, Akio Takahashi, Yoshiyuki Ishii, Shigeru Kyuwa, Keiji Wada, and Yasuhiro Yoshikawa Localization of Ubiquitin C-Terminal Hydrolase L1 in Mouse Ova and Its Function in the Plasma Membrane to Block Polyspermy Am J Pathol 2006 169: 1722-1729. ; doi: 10.2353/ajpath.2006.060301 [Abstract] [Full Text] [PDF]   Hicham Id Boufker, Henri Alexandre, Yves Carlier, and Carine Truyens Infertility in Murine Acute Trypanosoma cruzi Infection Is Associated with Inhibition of Pre-Implantation Embryo Development Am J Pathol 2006 169: 1730-1738. ; doi: 10.2353/ajpath.2006.060309 [Abstract] [Full Text] [PDF]

Tumorigenesis and Neoplastic Progression: Scott A. Gerber, Viktoriya Y. Rybalko, Chad E. Bigelow, Amit A. Lugade, Thomas H. Foster, John G. Frelinger, and Edith M. Lord Preferential Attachment of Peritoneal Tumor Metastases to Omental Immune Aggregates and Possible Role of a Unique Vascular Microenvironment in Metastatic Survival and Growth Am J Pathol 2006 169: 1739-1752. ; doi: 10.2353/ajpath.2006.051222 [Abstract] [Full Text] [PDF]   Jamie S. Mader, Daniel Smyth, Jean Marshall, and David W. Hoskin Bovine Lactoferricin Inhibits Basic Fibroblast Growth Factor- and Vascular Endothelial Growth Factor165-Induced Angiogenesis by Competing for Heparin-Like Binding Sites on Endothelial Cells Am J Pathol 2006 169: 1753-1766. ; doi: 10.2353/ajpath.2006.051229 [Abstract] [Full Text] [PDF]   Wiltrud Lederle, Hans-Jürgen Stark, Mihaela Skobe, Norbert E. Fusenig, and Margareta M. Mueller Platelet-Derived Growth Factor-BB Controls Epithelial Tumor Phenotype by Differential Growth Factor Regulation in Stromal Cells Am J Pathol 2006 169: 1767-1783. ; doi: 10.2353/ajpath.2006.060120 [Abstract] [Full Text] [PDF]   Terence M. Williams, Federica Sotgia, Hyangkyu Lee, Ghada Hassan, Dolores Di Vizio, Gloria Bonuccelli, Franco Capozza, Isabelle Mercier, Hallgeir Rui, Richard G. Pestell, and Michael P. Lisanti Stromal and Epithelial Caveolin-1 Both Confer a Protective Effect Against Mammary Hyperplasia and Tumorigenesis: Caveolin-1 Antagonizes Cyclin D1 Function in Mammary Epithelial Cells Am J Pathol 2006 169: 1784-1801. ; doi: 10.2353/ajpath.2006.060590 [Abstract] [Full Text] [PDF]   Joerg Galle, Doreen Sittig, Isabelle Hanisch, Manja Wobus, Elke Wandel, Markus Loeffler, and Gabriela Aust Individual Cell-Based Models of Tumor-Environment Interactions: Multiple Effects of CD97 on Tumor Invasion Am J Pathol 2006 169: 1802-1811. ; doi: 10.2353/ajpath.2006.060006 [Abstract] [Full Text] [PDF] Supplemental Material   Simion Chiosea, Elena Jelezcova, Uma Chandran, Marie Acquafondata, Teresa McHale, Robert W. Sobol, and Rajiv Dhir Up-Regulation of Dicer, a Component of the MicroRNA Machinery, in Prostate Adenocarcinoma Am J Pathol 2006 169: 1812-1820. ; doi: 10.2353/ajpath.2006.060480 [Abstract] [Full Text] [PDF]   Teresa A. Rose-Hellekant, Kristin M. Wentworth, Sarah Nikolai, Donald W. Kundel, and Eric P. Sandgren Mammary Carcinogenesis Is Preceded by Altered Epithelial Cell Turnover in Transforming Growth Factor- and c-myc Transgenic Mice Am J Pathol 2006 169: 1821-1832. ; doi: 10.2353/ajpath.2006.050675 [Abstract] [Full Text] [PDF]   Yabing Chen, Jianmin Xu, Nirag Jhala, Pritish Pawar, Zeng B. Zhu, Liping Ma, Chang-Hyun Byon, and Jay M. McDonald Fas-Mediated Apoptosis in Cholangiocarcinoma Cells Is Enhanced by 3,3'-Diindolylmethane through Inhibition of AKT Signaling and FLICE-Like Inhibitory Protein Am J Pathol 2006 169: 1833-1842. ; doi: 10.2353/ajpath.2006.060234 [Abstract] [Full Text] [PDF]   Thomas A. Dunn, Shenglin Chen, Dennis A. Faith, Jessica L. Hicks, Elizabeth A. Platz, Yidong Chen, Charles M. Ewing, Jurga Sauvageot, William B. Isaacs, Angelo M. De Marzo, and Jun Luo A Novel Role of Myosin VI in Human Prostate Cancer Am J Pathol 2006 169: 1843-1854. ; doi: 10.2353/ajpath.2006.060316 [Abstract] [Full Text] [PDF] Supplemental Material

Vascular Biology, Atherosclerosis and Endothelium Biology: Vincent Fontaine, Cédric Filipe, Nikos Werner, Pierre Gourdy, Audrey Billon, Barbara Garmy-Susini, Laurent Brouchet, Francis Bayard, Hervé Prats, Thomas Doetschman, Georg Nickenig, and Jean-François Arnal Essential Role of Bone Marrow Fibroblast Growth Factor-2 in the Effect of Estradiol on Reendothelialization and Endothelial Progenitor Cell Mobilization Am J Pathol 2006 169: 1855-1862. ; doi: 10.2353/ajpath.2006.060260 [Abstract] [Full Text] [PDF]   Lynda K. Harris, Rosemary J. Keogh, Mark Wareing, Philip N. Baker, Judith E. Cartwright, John D. Aplin, and Guy St J. Whitley Invasive Trophoblasts Stimulate Vascular Smooth Muscle Cell Apoptosis by a Fas Ligand-Dependent Mechanism Am J Pathol 2006 169: 1863-1874. ; doi: 10.2353/ajpath.2006.060265 [Abstract] [Full Text] [PDF]   Danielle A. Murphy, Sosina Makonnen, Wiem Lassoued, Michael D. Feldman, Christopher Carter, and William M.F. Lee Inhibition of Tumor Endothelial ERK Activation, Angiogenesis, and Tumor Growth by Sorafenib (BAY43-9006) Am J Pathol 2006 169: 1875-1885. ; doi: 10.2353/ajpath.2006.050711 [Abstract] [Full Text] [PDF] Supplemental Material   Dianhong Luo, Yan Luo, Yun He, Haifeng Zhang, Rong Zhang, Xianghong Li, Wawrzyniec L. Dobrucki, Al J. Sinusas, William C. Sessa, and Wang Min Differential Functions of Tumor Necrosis Factor Receptor 1 and 2 Signaling in Ischemia-Mediated Arteriogenesis and Angiogenesis Am J Pathol 2006 169: 1886-1898. ; doi: 10.2353/ajpath.2006.060603 [Abstract] [Full Text] [PDF] Supplemental Material

Correction: Corrections Am J Pathol 2006 169: 1899. ; doi: 10.2353/ajpath.2006.060864 [Full Text] [PDF]

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