Amgen Award Lecture: Jerrold R. Turner Molecular Basis of Epithelial Barrier Regulation: From Basic Mechanisms to Clinical Application Am J Pathol 2006 169: 1901-1909. [Abstract] [Full Text] [PDF]

Commentaries: Philippe G. Frank and Michael P. Lisanti Zebrafish as a Novel Model System to Study the Function of Caveolae and Caveolin-1 in Organismal Biology Am J Pathol 2006 169: 1910-1912. [Full Text] [PDF]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Roberta Fiaccavento, Felicia Carotenuto, Marilena Minieri, Laura Masuelli, Alba Vecchini, Roberto Bei, Andrea Modesti, Luciano Binaglia, Angelo Fusco, Aldo Bertoli, Giancarlo Forte, Luciana Carosella, and Paolo Di Nardo -Linolenic Acid-Enriched Diet Prevents Myocardial Damage and Expands Longevity in Cardiomyopathic Hamsters Am J Pathol 2006 169: 1913-1924. [Abstract] [Full Text] [PDF]   Miliyun G. Chiu, Tanya M. Johnson, Adrian S. Woolf, Eugenia M. Dahm-Vicker, David A. Long, Lisa Guay-Woodford, Katherine A. Hillman, Suleman Bawumia, Kerrie Venner, R. Colin Hughes, Francoise Poirier, and Paul J.D. Winyard Galectin-3 Associates with the Primary Cilium and Modulates Cyst Growth in Congenital Polycystic Kidney Disease Am J Pathol 2006 169: 1925-1938. [Abstract] [Full Text] [PDF]   Grace Fortes Monis, Christopher Schultz, Ruiyi Ren, Jeremy Eberhard, Catherine Costello, Lawreen Connors, Martha Skinner, and Vickery Trinkaus-Randall Role of Endocytic Inhibitory Drugs on Internalization of Amyloidogenic Light Chains by Cardiac Fibroblasts Am J Pathol 2006 169: 1939-1952. [Abstract] [Full Text] [PDF] Supplemental Material   Jian-Jun Wen, Vandanajay Bhatia, Vsevolod L. Popov, and Nisha Jain Garg Phenyl--tert-Butyl Nitrone Reverses Mitochondrial Decay in Acute Chagas’ Disease Am J Pathol 2006 169: 1953-1964. [Abstract] [Full Text] [PDF]   Marina Morigi, Simona Buelli, Cristina Zanchi, Lorena Longaretti, Daniela Macconi, Ariela Benigni, Daniela Moioli, Giuseppe Remuzzi, and Carla Zoja Shigatoxin-Induced Endothelin-1 Expression in Cultured Podocytes Autocrinally Mediates Actin Remodeling Am J Pathol 2006 169: 1965-1975. [Abstract] [Full Text] [PDF]

Cell Injury, Repair, Aging and Apoptosis: Bum-Chan Park, Xiang Shen, Mishan Samaraweera, and Beatrice Y.J.T. Yue Studies of Optineurin, a Glaucoma Gene: Golgi Fragmentation and Cell Death from Overexpression of Wild-Type and Mutant Optineurin in Two Ocular Cell Types Am J Pathol 2006 169: 1976-1989. [Abstract] [Full Text] [PDF]   Antje Wurm, Thomas Pannicke, Ianors Iandiev, Eva Bühner, Uta-Carolin Pietsch, Andreas Reichenbach, Peter Wiedemann, Susann Uhlmann, and Andreas Bringmann Changes in Membrane Conductance Play a Pathogenic Role in Osmotic Glial Cell Swelling in Detached Retinas Am J Pathol 2006 169: 1990-1998. [Abstract] [Full Text] [PDF]

Gastrointestinal, Hepatobiliary and Pancreatic Pathology: Xiaonan Han, Bankole Osuntokun, Nancy Benight, Kimberly Loesch, Stuart J. Frank, and Lee A. Denson Signal Transducer and Activator of Transcription 5b Promotes Mucosal Tolerance in Pediatric Crohn’s Disease and Murine Colitis Am J Pathol 2006 169: 1999-2013. [Abstract] [Full Text] [PDF]   John H. Chidlow, Jr., Will Langston, James J.M. Greer, Dmitry Ostanin, Maisoun Abdelbaqi, Jeffery Houghton, Annamalai Senthilkumar, Deepti Shukla, Andrew P. Mazar, Matthew B. Grisham, and Christopher G. Kevil Differential Angiogenic Regulation of Experimental Colitis Am J Pathol 2006 169: 2014-2030. [Abstract] [Full Text] [PDF]   Laetitia Finzi, Véronique Barbu, Pierre-Regis Burgel, Martine Mergey, Kimberly S. Kirkwood, Elizabeth C. Wick, Jean-Yves Scoazec, Frédérique Peschaud, François Paye, Jay A. Nadel, and Chantal Housset MUC5AC, a Gel-Forming Mucin Accumulating in Gallstone Disease, Is Overproduced via an Epidermal Growth Factor Receptor Pathway in the Human Gallbladder Am J Pathol 2006 169: 2031-2041. [Abstract] [Full Text] [PDF]   Cristiana Bertolani, Pau Sancho-Bru, Paola Failli, Ramon Bataller, Sara Aleffi, Raffaella DeFranco, Benedetta Mazzinghi, Paola Romagnani, Stefano Milani, Pere Ginés, Jordi Colmenero, Maurizio Parola, Stefania Gelmini, Roberto Tarquini, Giacomo Laffi, Massimo Pinzani, and Fabio Marra Resistin as an Intrahepatic Cytokine: Overexpression during Chronic Injury and Induction of Proinflammatory Actions in Hepatic Stellate Cells Am J Pathol 2006 169: 2042-2053. [Abstract] [Full Text] [PDF]

Growth Factors, Cytokines, Cell Cycle Molecules: Yasuhiko Kitadai, Takamitsu Sasaki, Toshio Kuwai, Toru Nakamura, Corazon D. Bucana, and Isaiah J. Fidler Targeting the Expression of Platelet-Derived Growth Factor Receptor by Reactive Stroma Inhibits Growth and Metastasis of Human Colon Carcinoma Am J Pathol 2006 169: 2054-2065. [Abstract] [Full Text] [PDF]   Donghang Zheng, Seh-hoon Oh, Youngmi Jung, and Bryon E. Petersen Oval Cell Response in 2-Acetylaminofluorene/Partial Hepatectomy Rat Is Attenuated by Short Interfering RNA Targeted to Stromal Cell-Derived Factor-1 Am J Pathol 2006 169: 2066-2074. [Abstract] [Full Text] [PDF] Supplemental Material   Michael Y. Fessing, Tatyana Y. Sharova, Andrey A. Sharov, Ruzanna Atoyan, and Vladimir A. Botchkarev Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen) Am J Pathol 2006 169: 2075-2084. [Abstract] [Full Text] [PDF]

Immunopathology and Infectious Disease: Gudrun Szalay, Martina Sauter, Joachim Hald, Andreas Weinzierl, Reinhard Kandolf, and Karin Klingel Sustained Nitric Oxide Synthesis Contributes to Immunopathology in Ongoing Myocarditis Attributable to Interleukin-10 Disorders Am J Pathol 2006 169: 2085-2093. [Abstract] [Full Text] [PDF]   Vanessa Roulet, Anne-Pascale Satie, Annick Ruffault, Anna Le Tortorec, Hélène Denis, Odile Guist’hau, Jean-Jacques Patard, Nathalie Rioux-Leclerq, Janine Gicquel, Bernard Jégou, and Nathalie Dejucq-Rainsford Susceptibility of Human Testis to Human Immunodeficiency Virus-1 Infection in Situ and in Vitro Am J Pathol 2006 169: 2094-2103. [Abstract] [Full Text] [PDF]   Stephen J. Crocker, Jason K. Whitmire, Ricardo F. Frausto, Parntip Chertboonmuang, Paul D. Soloway, J. Lindsay Whitton, and Iain L. Campbell Persistent Macrophage/Microglial Activation and Myelin Disruption after Experimental Autoimmune Encephalomyelitis in Tissue Inhibitor of Metalloproteinase-1-Deficient Mice Am J Pathol 2006 169: 2104-2116. [Abstract] [Full Text] [PDF]   Patricia C. Fulkerson, Christine A. Fischetti, and Marc E. Rothenberg Eosinophils and CCR3 Regulate Interleukin-13 Transgene-Induced Pulmonary Remodeling Am J Pathol 2006 169: 2117-2126. [Abstract] [Full Text] [PDF]   Carolina Obregon, Barbara Rothen-Rutishauser, Stephen Kiama Gitahi, Peter Gehr, and Laurent P. Nicod Exovesicles from Human Activated Dendritic Cells Fuse with Resting Dendritic Cells, Allowing Them to Present Alloantigens Am J Pathol 2006 169: 2127-2136. [Abstract] [Full Text] [PDF]   Boris Calderon, Anish Suri, and Emil R. Unanue In CD4+ T-Cell-Induced Diabetes, Macrophages Are the Final Effector Cells that Mediate Islet ß-Cell Killing: Studies from an Acute Model Am J Pathol 2006 169: 2137-2147. [Abstract] [Full Text] [PDF]

Musculoskeletal Pathology: Christian A. Shaw, Nancy Larochelle, Roy W.R. Dudley, Hanns Lochmuller, Gawiyou Danialou, Basil J. Petrof, George Karpati, Paul C. Holland, and Josephine Nalbantoglu Simultaneous Dystrophin and Dysferlin Deficiencies Associated with High-Level Expression of the Coxsackie and Adenovirus Receptor in Transgenic Mice Am J Pathol 2006 169: 2148-2160. [Abstract] [Full Text] [PDF]   Despina Sitara, Mohammed S. Razzaque, René St-Arnaud, Wei Huang, Takashi Taguchi, Reinhold G. Erben, and Beate Lanske Genetic Ablation of Vitamin D Activation Pathway Reverses Biochemical and Skeletal Anomalies in Fgf-23-Null Animals Am J Pathol 2006 169: 2161-2170. [Abstract] [Full Text] [PDF]

Tumorigenesis and Neoplastic Progression: Evangelia Peponi, Elias Drakos, Guadalupe Reyes, Vasiliki Leventaki, George Z. Rassidakis, and L. Jeffrey Medeiros Activation of Mammalian Target of Rapamycin Signaling Promotes Cell Cycle Progression and Protects Cells from Apoptosis in Mantle Cell Lymphoma Am J Pathol 2006 169: 2171-2180. [Abstract] [Full Text] [PDF]   Halina Was, Tomasz Cichon, Ryszard Smolarczyk, Dominika Rudnicka, Magdalena Stopa, Catherine Chevalier, Jean J. Leger, Bozena Lackowska, Anna Grochot, Karolina Bojkowska, Anna Ratajska, Claudine Kieda, Stanislaw Szala, Jozef Dulak, and Alicja Jozkowicz Overexpression of Heme Oxygenase-1 in Murine Melanoma: Increased Proliferation and Viability of Tumor Cells, Decreased Survival of Mice Am J Pathol 2006 169: 2181-2198. [Abstract] [Full Text] [PDF]   Ilaria Bellezza, Hannes Neuwirt, Constanze Nemes, Ilaria T. Cavarretta, Martin Puhr, Hannes Steiner, Alba Minelli, Georg Bartsch, Felix Offner, Alfred Hobisch, Wolfgang Doppler, and Zoran Culig Suppressor of Cytokine Signaling-3 Antagonizes cAMP Effects on Proliferation and Apoptosis and Is Expressed in Human Prostate Cancer Am J Pathol 2006 169: 2199-2208. [Abstract] [Full Text] [PDF]

Vascular Biology, Atherosclerosis and Endothelium Biology: Ping-Ke Fang, Keith R. Solomon, Liyan Zhuang, Maosong Qi, Mary McKee, Michael R. Freeman, and Pamela C. Yelick Caveolin-1 and -1ß Perform Nonredundant Roles in Early Vertebrate Development Am J Pathol 2006 169: 2209-2222. [Abstract] [Full Text] [PDF]   Stefania Bruno, Benedetta Bussolati, Cristina Grange, Federica Collino, Manuela Efrem Graziano, Ugo Ferrando, and Giovanni Camussi CD133+ Renal Progenitor Cells Contribute to Tumor Angiogenesis Am J Pathol 2006 169: 2223-2235. [Abstract] [Full Text] [PDF]   Paola Secchiero, Federica Corallini, Assunta Pandolfi, Agostino Consoli, Riccardo Candido, Bruno Fabris, Claudio Celeghini, Silvano Capitani, and Giorgio Zauli An Increased Osteoprotegerin Serum Release Characterizes the Early Onset of Diabetes Mellitus and May Contribute to Endothelial Cell Dysfunction Am J Pathol 2006 169: 2236-2244. [Abstract] [Full Text] [PDF]   De-xiu Bu, Anne-Louise Hemdahl, Anders Gabrielsen, Jonas Fuxe, Chaoyong Zhu, Per Eriksson, and Zhong-qun Yan Induction of Neutrophil Gelatinase-Associated Lipocalin in Vascular Injury via Activation of Nuclear Factor-B Am J Pathol 2006 169: 2245-2253. [Abstract] [Full Text] [PDF]   Vineeth S. Rajkumar, Xu Shiwen, Maria Bostrom, Patricia Leoni, John Muddle, Mikael Ivarsson, Bengt Gerdin, Christopher P. Denton, George Bou-Gharios, Carol M. Black, and David J. Abraham Platelet-Derived Growth Factor-ß Receptor Activation Is Essential for Fibroblast and Pericyte Recruitment during Cutaneous Wound Healing Am J Pathol 2006 169: 2254-2265. [Abstract] [Full Text] [PDF]

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