Biological Perspectives: Balázs Döme, Mary J.C. Hendrix, Sándor Paku, József Tóvári, and József Tímár Alternative Vascularization Mechanisms in Cancer: Pathology and Therapeutic Implications Am J Pathol 2007 170: 1-15. [Abstract] [Full Text] [PDF]

Commentaries: Dennis W. Dickson Linking Selective Vulnerability to Cell Death Mechanisms in Parkinson’s Disease Am J Pathol 2007 170: 16-19. [Full Text] [PDF]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Daphne Yuan-chen Wu, Reen Wu, Sekhar P. Reddy, Yong Chan Lee, and Mary Mann-Jong Chang Distinctive Epidermal Growth Factor Receptor/Extracellular Regulated Kinase-Independent and -Dependent Signaling Pathways in the Induction of Airway Mucin 5B and Mucin 5AC Expression by Phorbol 12-Myristate 13-Acetate Am J Pathol 2007 170: 20-32. [Abstract] [Full Text] [PDF]   Luigi Giusto Spagnoli, Sabina Pucci, Elena Bonanno, Antonio Cassone, Fabiola Sesti, Alessandra Ciervo, and Alessandro Mauriello Persistent Chlamydia pneumoniae Infection of Cardiomyocytes Is Correlated with Fatal Myocardial Infarction Am J Pathol 2007 170: 33-42. [Abstract] [Full Text] [PDF]   Yoh Matsumoto, Il-Kwon Park, and Kuniko Kohyama B-Cell Epitope Spreading Is a Critical Step for the Switch from C-Protein-Induced Myocarditis to Dilated Cardiomyopathy Am J Pathol 2007 170: 43-51. [Abstract] [Full Text] [PDF]   Hong Xiao, Adrian Schreiber, Peter Heeringa, Ronald J. Falk, and J. Charles Jennette Alternative Complement Pathway in the Pathogenesis of Disease Mediated by Anti-Neutrophil Cytoplasmic Autoantibodies Am J Pathol 2007 170: 52-64. [Abstract] [Full Text] [PDF]   Felix Chua, Sarah E. Dunsmore, Peter H. Clingen, Steven E. Mutsaers, Steven D. Shapiro, Anthony W. Segal, Jürgen Roes, and Geoffrey J. Laurent Mice Lacking Neutrophil Elastase Are Resistant to Bleomycin-Induced Pulmonary Fibrosis Am J Pathol 2007 170: 65-74. [Abstract] [Full Text] [PDF] Supplemental Material

Cell Injury, Repair, Aging and Apoptosis: Jian-hui Zhu, Craig Horbinski, Fengli Guo, Simon Watkins, Yasuo Uchiyama, and Charleen T. Chu Regulation of Autophagy by Extracellular Signal-Regulated Protein Kinases During 1-Methyl-4-Phenylpyridinium-Induced Cell Death Am J Pathol 2007 170: 75-86. [Abstract] [Full Text] [PDF]   Michael S. Forbes, Barbara A. Thornhill, Matthew H. Park, and Robert L. Chevalier Lack of Endothelial Nitric-Oxide Synthase Leads to Progressive Focal Renal Injury Am J Pathol 2007 170: 87-99. [Abstract] [Full Text] [PDF]   Gary Hin-Fai Yam, Katarina Gaplovska-Kysela, Christian Zuber, and Jürgen Roth Aggregated Myocilin Induces Russell Bodies and Causes Apoptosis: Implications for the Pathogenesis of Myocilin-Caused Primary Open-Angle Glaucoma Am J Pathol 2007 170: 100-109. [Abstract] [Full Text] [PDF]

Epithelial and Mesenchymal Cell Biology: Kyungmin Hahm, Matvey E. Lukashev, Yi Luo, William J. Yang, Brian M. Dolinski, Paul H. Weinreb, Kenneth J. Simon, Li Chun Wang, Diane R. Leone, Roy R. Lobb, Donald J. McCrann, Normand E. Allaire, Gerald S. Horan, Agnes Fogo, Raghu Kalluri, Charles F. Shield, III, Dean Sheppard, Humphrey A. Gardner, and Shelia M. Violette vß6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse Am J Pathol 2007 170: 110-125. [Abstract] [Full Text] [PDF] Supplemental Material   Birgit Gellersen, Juliane Briese, Marine Oberndörfer, Katja Redlin, Annemarie Samalecos, Dagmar-Ulrike Richter, Thomas Löning, Heinrich-Maria Schulte, and Ana-Maria Bamberger Expression of the Metastasis Suppressor KAI1 in Decidual Cells at the Human Maternal-Fetal Interface: Regulation and Functional Implications Am J Pathol 2007 170: 126-139. [Abstract] [Full Text] [PDF]   Arti Shukla, Karen M. Lounsbury, Trisha F. Barrett, Joanna Gell, Mercedes Rincon, Kelly J. Butnor, Douglas J. Taatjes, Gerald S. Davis, Pamela Vacek, Keiichi I. Nakayama, Keiko Nakayama, Chad Steele, and Brooke T. Mossman Asbestos-Induced Peribronchiolar Cell Proliferation and Cytokine Production Are Attenuated in Lungs of Protein Kinase C- Knockout Mice Am J Pathol 2007 170: 140-151. [Abstract] [Full Text] [PDF]   Ying Qiu, Yasuhiko Tomita, Binglin Zhang, Itsuko Nakamichi, Eiichi Morii, and Katsuyuki Aozasa Pre-B-Cell Leukemia Transcription Factor 1 Regulates Expression of Valosin-Containing Protein, a Gene Involved in Cancer Growth Am J Pathol 2007 170: 152-159. [Abstract] [Full Text] [PDF]

Growth Factors, Cytokines, Cell Cycle Molecules: Ruth Schwaninger, Cyrill A. Rentsch, Antoinette Wetterwald, Geertje van der Horst, Rutger L. van Bezooijen, Gabri van der Pluijm, Clemens W.G.M. Löwik, Karin Ackermann, Walter Pyerin, Freddie C. Hamdy, George N. Thalmann, and Marco G. Cecchini Lack of Noggin Expression by Cancer Cells Is a Determinant of the Osteoblast Response in Bone Metastases Am J Pathol 2007 170: 160-175. [Abstract] [Full Text] [PDF] Supplemental Material   Sandra March, Mariona Graupera, María Rosa Sarrias, Francisco Lozano, Pilar Pizcueta, Jaume Bosch, and Pablo Engel Identification and Functional Characterization of the Hepatic Stellate Cell CD38 Cell Surface Molecule Am J Pathol 2007 170: 176-187. [Abstract] [Full Text] [PDF]   Sabine A. Eming, Sabine Werner, Philippe Bugnon, Claudia Wickenhauser, Lisa Siewe, Olaf Utermöhlen, Jeffrey M. Davidson, Thomas Krieg, and Axel Roers Accelerated Wound Closure in Mice Deficient for Interleukin-10 Am J Pathol 2007 170: 188-202. [Abstract] [Full Text] [PDF]

Immunopathology and Infectious Disease: Philip Stashenko, Reginaldo B. Gonçalves, Brad Lipkin, Alexander Ficarelli, Hajime Sasaki, and Antonio Campos-Neto Th1 Immune Response Promotes Severe Bone Resorption Caused by Porphyromonas gingivalis Am J Pathol 2007 170: 203-213. [Abstract] [Full Text] [PDF]   Ikuo Tsunoda, Tomoko Tanaka, Emily Jane Terry, and Robert S. Fujinami Contrasting Roles for Axonal Degeneration in an Autoimmune versus Viral Model of Multiple Sclerosis: When Can Axonal Injury Be Beneficial? Am J Pathol 2007 170: 214-226. [Abstract] [Full Text] [PDF]   Liv Eidsmo, Caroline Fluur, Bence Rethi, Sofia Eriksson Ygberg, Nicolas Ruffin, Angelo De Milito, Hannah Akuffo, and Francesca Chiodi FasL and TRAIL Induce Epidermal Apoptosis and Skin Ulceration Upon Exposure to Leishmania major Am J Pathol 2007 170: 227-239. [Abstract] [Full Text] [PDF] Supplemental Material   Arno Hänninen, Rita Nurmela, Mikael Maksimow, Jarkko Heino, Sirpa Jalkanen, and Christian Kurts Islet ß-Cell-Specific T Cells Can Use Different Homing Mechanisms to Infiltrate and Destroy Pancreatic Islets Am J Pathol 2007 170: 240-250. [Abstract] [Full Text] [PDF]   Harald Gelderblom, Jens Schmidt, Diana Londoño, Yunhong Bai, Jacqueline Quandt, Ron Hornung, Adriana Marques, Roland Martin, and Diego Cadavid Role of Interleukin 10 during Persistent Infection with the Relapsing Fever Spirochete Borrelia turicatae Am J Pathol 2007 170: 251-262. [Abstract] [Full Text] [PDF]   Elena Gonzalez-Rey, Alejo Chorny, Francisco O’Valle, and Mario Delgado Adrenomedullin Protects from Experimental Arthritis by Down-Regulating Inflammation and Th1 Response and Inducing Regulatory T Cells Am J Pathol 2007 170: 263-271. [Abstract] [Full Text] [PDF]   Junda Kel, Judith Oldenampsen, Mariken Luca, Jan Wouter Drijfhout, Frits Koning, and Lex Nagelkerken Soluble Mannosylated Myelin Peptide Inhibits the Encephalitogenicity of Autoreactive T Cells during Experimental Autoimmune Encephalomyelitis Am J Pathol 2007 170: 272-280. [Abstract] [Full Text] [PDF]

Matrix Pathobiology: Christina D. Keller, Pilar Rivera Gil, Markus Tölle, Markus van der Giet, Jerold Chun, Heinfried H. Radeke, Monika Schäfer-Korting, and Burkhard Kleuser Immunomodulator FTY720 Induces Myofibroblast Differentiation via the Lysophospholipid Receptor S1P3 and Smad3 Signaling Am J Pathol 2007 170: 281-292. [Abstract] [Full Text] [PDF]   Thomas M. Merritt, Roger Bick, Brian J. Poindexter, Joseph L. Alcorn, and Jacqueline T. Hecht Unique Matrix Structure in the Rough Endoplasmic Reticulum Cisternae of Pseudoachondroplasia Chondrocytes Am J Pathol 2007 170: 293-300. [Abstract] [Full Text] [PDF]   Liliana Schaefer, Wasiliki Tsalastra, Andrea Babelova, Martina Baliova, Jens Minnerup, Lydia Sorokin, Hermann-Josef Gröne, Dieter P. Reinhardt, Josef Pfeilschifter, Renato V. Iozzo, and Roland M. Schaefer Decorin-Mediated Regulation of Fibrillin-1 in the Kidney Involves the Insulin-Like Growth Factor-I Receptor and Mammalian Target of Rapamycin Am J Pathol 2007 170: 301-315. [Abstract] [Full Text] [PDF]

Musculoskeletal Pathology: William Schubert, Federica Sotgia, Alex W. Cohen, Franco Capozza, Gloria Bonuccelli, Claudio Bruno, Carlo Minetti, Eduardo Bonilla, Salvatore DiMauro, and Michael P. Lisanti Caveolin-1(–/–)- and Caveolin-2(–/–)-Deficient Mice Both Display Numerous Skeletal Muscle Abnormalities, with Tubular Aggregate Formation Am J Pathol 2007 170: 316-333. [Abstract] [Full Text] [PDF] Supplemental Material

Tumorigenesis and Neoplastic Progression: Giacomo Azzali Tumor Cell Transendothelial Passage in the Absorbing Lymphatic Vessel of Transgenic Adenocarcinoma Mouse Prostate Am J Pathol 2007 170: 334-346. [Abstract] [Full Text] [PDF]   Eli E. Bar, Aneeka Chaudhry, Mohamed H. Farah, and Charles G. Eberhart Hedgehog Signaling Promotes Medulloblastoma Survival via BclII Am J Pathol 2007 170: 347-355. [Abstract] [Full Text] [PDF]   Isa M. Hussaini, Christy Trotter, Yunge Zhao, Rana Abdel-Fattah, Samson Amos, Aizhen Xiao, Crystal U. Agi, Gerard T. Redpath, Zixing Fang, Gilberto K.K. Leung, Maria Beatriz S. Lopes, and Edward R. Laws, Jr Matrix Metalloproteinase-9 Is Differentially Expressed in Nonfunctioning Invasive and Noninvasive Pituitary Adenomas and Increases Invasion in Human Pituitary Adenoma Cell Line Am J Pathol 2007 170: 356-365. [Abstract] [Full Text] [PDF]   Jie Zhang, Shailaja Kalyankrishna, Marie Wislez, Nishan Thilaganathan, Babita Saigal, Wei Wei, Long Ma, Ignacio I. Wistuba, Faye M. Johnson, and Jonathan M. Kurie Src-Family Kinases Are Activated in Non-Small Cell Lung Cancer and Promote the Survival of Epidermal Growth Factor Receptor-Dependent Cell Lines Am J Pathol 2007 170: 366-376. [Abstract] [Full Text] [PDF]   Paola Alberici, Emma de Pater, Joana Cardoso, Mieke Bevelander, Lia Molenaar, Jos Jonkers, and Riccardo Fodde Aneuploidy Arises at Early Stages of Apc-Driven Intestinal Tumorigenesis and Pinpoints Conserved Chromosomal Loci of Allelic Imbalance between Mouse and Human Am J Pathol 2007 170: 377-387. [Abstract] [Full Text] [PDF]

Vascular Biology, Atherosclerosis and Endothelium Biology: Anna Csiszar, Nazar Labinskyy, Kira Smith, Aracelie Rivera, Zsuzsanna Orosz, and Zoltan Ungvari Vasculoprotective Effects of Anti-Tumor Necrosis Factor- Treatment in Aging Am J Pathol 2007 170: 388-698. [Abstract] [Full Text] [PDF]   Xiujie Li, Ezequiel Calvo, Marc Cool, Pavel Chrobak, Denis G. Kay, and Paul Jolicoeur Overexpression of Notch1 Ectodomain in Myeloid Cells Induces Vascular Malformations through a Paracrine Pathway Am J Pathol 2007 170: 399-415. [Abstract] [Full Text] [PDF] Supplemental Material   Vinay K. Bhatia, Sheng Yun, Viola Leung, David C. Grimsditch, G. Martin Benson, Marina B. Botto, Joseph J. Boyle, and Dorian O. Haskard Complement C1q Reduces Early Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice Am J Pathol 2007 170: 416-426. [Abstract] [Full Text] [PDF]

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