On the Cover: As demonstrated by its abnormality in FAK^{K5 KO} mice, focal adhesion kinase (FAK) is required for proper epidermal permeability barrier acidification by mediating actin-dependent plasma membrane localization of Na⁺/H⁺ exchanger (NHE1). Shown is a schematic drawing of mouse skin depicting epidermal permeability barrier within the stratum corneum (inset). Illustration by Joseph Hill. (see page 2055)

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