Amgen Award Lecture: Jonathan R. Pollack A Perspective on DNA Microarrays in Pathology Research and Practice Am J Pathol 2007 171: 375-385. First published online June 28, 2007; doi:10.2353/ajpath.2007.070342 [Abstract] [Full Text] [PDF]

Reviews: Monika Trzpis, Pamela M.J. McLaughlin, Lou M.F.H. de Leij, and Martin C. Harmsen Epithelial Cell Adhesion Molecule: More than a Carcinoma Marker and Adhesion Molecule Am J Pathol 2007 171: 386-395. First published online June 28, 2007; doi:10.2353/ajpath.2007.070152 [Abstract] [Full Text] [PDF]

Commentaries: Ralph Feuer Tickling the CD200 Receptor: A Remedy for Those Irritating Macrophages Am J Pathol 2007 171: 396-398. First published online June 28, 2007; doi:10.2353/ajpath.2007.070474 [Full Text] [PDF]   Melanie A. Sherman The Role of Mast Cells in Bacterial Enteritis Am J Pathol 2007 171: 399-401. First published online June 14, 2007; doi:10.2353/ajpath.2007.070501 [Full Text] [PDF]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Masashi Mizuno, Masatoshi Nozaki, Nobuya Morine, Norihiko Suzuki, Kazuhiro Nishikawa, B. Paul Morgan, and Seiichi Matsuo A Protein Toxin from the Sea Anemone Phyllodiscus semoni Targets the Kidney and Causes a Severe Renal Injury with Predominant Glomerular Endothelial Damage Am J Pathol 2007 171: 402-414. First published online June 28, 2007; doi:10.2353/ajpath.2007.060984 [Abstract] [Full Text] [PDF]   Etsuko Yanagida-Asanuma, Katsuhiko Asanuma, Kwanghee Kim, Mary Donnelly, Hoon Young Choi, Jae Hyung Chang, Shiro Suetsugu, Yasuhiko Tomino, Tadaomi Takenawa, Christian Faul, and Peter Mundel Synaptopodin Protects Against Proteinuria by Disrupting Cdc42:IRSp53:Mena Signaling Complexes in Kidney Podocytes Am J Pathol 2007 171: 415-427. First published online June 14, 2007; doi:10.2353/ajpath.2007.070075 [Abstract] [Full Text] [PDF]   Kerill Pochetuhen, Irina G. Luzina, Virginia Lockatell, Jung Choi, Nevins W. Todd, and Sergei P. Atamas Complex Regulation of Pulmonary Inflammation and Fibrosis by CCL18 Am J Pathol 2007 171: 428-437. First published online June 14, 2007; doi:10.2353/ajpath.2007.061167 [Abstract] [Full Text] [PDF]   Denise W. Wong, Gavin Y. Oudit, Heather Reich, Zamaneh Kassiri, Joyce Zhou, Qiao C. Liu, Peter H. Backx, Josef M. Penninger, Andrew M. Herzenberg, and James W. Scholey Loss of Angiotensin-Converting Enzyme-2 (Ace2) Accelerates Diabetic Kidney Injury Am J Pathol 2007 171: 438-451. First published online June 28, 2007; doi:10.2353/ajpath.2007.060977 [Abstract] [Full Text] [PDF]   Maaike Alderliesten, Marjo de Graauw, Judith Oldenampsen, Yu Qin, Chantal Pont, Liesbeth van Buren, and Bob van de Water Extracellular Signal-Regulated Kinase Activation during Renal Ischemia/Reperfusion Mediates Focal Adhesion Dissolution and Renal Injury Am J Pathol 2007 171: 452-462. First published online July 9, 2007; doi:10.2353/ajpath.2007.060805 [Abstract] [Full Text] [PDF] Supplemental Material   Kurt Reifenberg, Hans-Anton Lehr, Michael Torzewski, Gisela Steige, Elena Wiese, Ines Küpper, Christoph Becker, Sibylle Ott, Petra Nusser, Ken-Ichi Yamamura, Gerd Rechtsteiner, Tobias Warger, Andrea Pautz, Hartmut Kleinert, Albrecht Schmidt, Burkert Pieske, Philip Wenzel, Thomas Münzel, and Jürgen Löhler Interferon- Induces Chronic Active Myocarditis and Cardiomyopathy in Transgenic Mice Am J Pathol 2007 171: 463-472. First published online June 7, 2007; doi:10.2353/ajpath.2007.060906 [Abstract] [Full Text] [PDF]   Sayuri Suzuki, Hirotaka Fukasawa, Kyoko Kitagawa, Chiharu Uchida, Takayuki Hattori, Tomoyasu Isobe, Toshiaki Oda, Taro Misaki, Naro Ohashi, Keiko Nakayama, Keiichi I. Nakayama, Akira Hishida, Tatsuo Yamamoto, and Masatoshi Kitagawa Renal Damage in Obstructive Nephropathy Is Decreased in Skp2-Deficient Mice Am J Pathol 2007 171: 473-483. First published online July 9, 2007; doi:10.2353/ajpath.2007.070279 [Abstract] [Full Text] [PDF] Supplemental Material

Cell Injury, Repair, Aging and Apoptosis: Cecelia C. Yates, Diana Whaley, Priya Kulasekeran, Wayne W. Hancock, Bao Lu, Richard Bodnar, Joseph Newsome, Patricia A. Hebda, and Alan Wells Delayed and Deficient Dermal Maturation in Mice Lacking the CXCR3 ELR-Negative CXC Chemokine Receptor Am J Pathol 2007 171: 484-495. First published online June 28, 2007; doi:10.2353/ajpath.2007.061092 [Abstract] [Full Text] [PDF]   Nima Soleymanlou, Andrea Jurisicova, Yuanhong Wu, Mari Chijiiwa, Jocelyn E. Ray, Jacqui Detmar, Tullia Todros, Stacy Zamudio, Martin Post, and Isabella Caniggia Hypoxic Switch in Mitochondrial Myeloid Cell Leukemia Factor-1/Mtd Apoptotic Rheostat Contributes to Human Trophoblast Cell Death in Preeclampsia Am J Pathol 2007 171: 496-506. First published online June 28, 2007; doi:10.2353/ajpath.2007.070094 [Abstract] [Full Text] [PDF]   Stefan Frantz, Jochen Tillmanns, Peter J. Kuhlencordt, Isabel Schmidt, Anna Adamek, Charlotte Dienesch, Thomas Thum, Steve Gerondakis, Georg Ertl, and Johann Bauersachs Tissue-Specific Effects of the Nuclear Factor B Subunit p50 on Myocardial Ischemia-Reperfusion Injury Am J Pathol 2007 171: 507-512. First published online June 7, 2007; doi:10.2353/ajpath.2007.061042 [Abstract] [Full Text] [PDF]   Wen-Xing Ding, Hong-Min Ni, Wentao Gao, Tamotsu Yoshimori, Donna B. Stolz, David Ron, and Xiao-Ming Yin Linking of Autophagy to Ubiquitin-Proteasome System Is Important for the Regulation of Endoplasmic Reticulum Stress and Cell Viability Am J Pathol 2007 171: 513-524. First published online July 9, 2007; doi:10.2353/ajpath.2007.070188 [Abstract] [Full Text] [PDF]

Gastrointestinal, Hepatobiliary and Pancreatic Pathology: Peter Fickert, Ulrike Stöger, Andrea Fuchsbichler, Tarek Moustafa, Hanns-Ulrich Marschall, Andreas H. Weiglein, Oleksiy Tsybrovskyy, Hartmut Jaeschke, Kurt Zatloukal, Helmut Denk, and Michael Trauner A New Xenobiotic-Induced Mouse Model of Sclerosing Cholangitis and Biliary Fibrosis Am J Pathol 2007 171: 525-536. First published online June 28, 2007; doi:10.2353/ajpath.2007.061133 [Abstract] [Full Text] [PDF] Supplemental Material   Bai-Sui Feng, Shao-Heng He, Peng-Yuan Zheng, Linda Wu, and Ping-Chang Yang Mast Cells Play a Crucial Role in Staphylococcus aureus Peptidoglycan-Induced Diarrhea Am J Pathol 2007 171: 537-547. First published online June 28, 2007; doi:10.2353/ajpath.2007.061274 [Abstract] [Full Text] [PDF]

Immunopathology and Infectious Disease: Fiona H. Amante, Amanda C. Stanley, Louise M. Randall, Yonghong Zhou, Ashraful Haque, Karli McSweeney, Andrew P. Waters, Chris J. Janse, Michael F. Good, Geoff R. Hill, and Christian R. Engwerda A Role for Natural Regulatory T Cells in the Pathogenesis of Experimental Cerebral Malaria Am J Pathol 2007 171: 548-559. First published online June 28, 2007; doi:10.2353/ajpath.2007.061033 [Abstract] [Full Text] [PDF] Supplemental Material   Rei Watanabe, Manabu Fujimoto, Nobuko Ishiura, Yoshihiro Kuwano, Hiroko Nakashima, Norihito Yazawa, Hitoshi Okochi, Shinichi Sato, Thomas F. Tedder, and Kunihiko Tamaki CD19 Expression in B Cells Is Important for Suppression of Contact Hypersensitivity Am J Pathol 2007 171: 560-570. First published online June 7, 2007; doi:10.2353/ajpath.2007.061279 [Abstract] [Full Text] [PDF]   Niki M. Moutsopoulos, Salvador Nares, Nikolaos Nikitakis, Zoila Rangel, Jie Wen, Peter Munson, John Sauk, and Sharon M. Wahl Tonsil Epithelial Factors May Influence Oropharyngeal Human Immunodeficiency Virus Transmission Am J Pathol 2007 171: 571-579. First published online July 9, 2007; doi:10.2353/ajpath.2007.061006 [Abstract] [Full Text] [PDF]   David A. Copland, Claudia J. Calder, Ben J.E. Raveney, Lindsay B. Nicholson, Joseph Phillips, Holly Cherwinski, Maria Jenmalm, Jonathon D. Sedgwick, and Andrew D. Dick Monoclonal Antibody-Mediated CD200 Receptor Signaling Suppresses Macrophage Activation and Tissue Damage in Experimental Autoimmune Uveoretinitis Am J Pathol 2007 171: 580-598. First published online June 28, 2007; doi:10.2353/ajpath.2007.070272 [Abstract] [Full Text] [PDF]

Neurobiology: Eva Herrero-Herranz, Luis A. Pardo, Gertrude Bunt, Ralf Gold, Walter Stühmer, and Ralf A. Linker Re-Expression of a Developmentally Restricted Potassium Channel in Autoimmune Demyelination: Kv1.4 Is Implicated in Oligodendroglial Proliferation Am J Pathol 2007 171: 589-598. First published online June 28, 2007; doi:10.2353/ajpath.2007.061241 [Abstract] [Full Text] [PDF] Supplemental Material   Jiaxin Dong, Aimin Li, Naohiro Yamaguchi, Suehiro Sakaguchi, and David A. Harris Doppel Induces Degeneration of Cerebellar Purkinje Cells Independently of Bax Am J Pathol 2007 171: 599-607. First published online June 14, 2007; doi:10.2353/ajpath.2007.070262 [Abstract] [Full Text] [PDF]   Michel Guipponi, Justin Tan, Ping Z.F. Cannon, Lauren Donley, Pauline Crewther, Maria Clarke, Qingyu Wu, Robert K. Shepherd, and Hamish S. Scott Mice Deficient for the Type II Transmembrane Serine Protease, TMPRSS1/hepsin, Exhibit Profound Hearing Loss Am J Pathol 2007 171: 608-616. First published online July 9, 2007; doi:10.2353/ajpath.2007.070068 [Abstract] [Full Text] [PDF] Supplemental Material

Stem Cells, Tissue Engineering and Hematopoietic Elements: Martin Wirenfeldt, Lasse Dissing-Olesen, Alicia Anne Babcock, Marianne Nielsen, Michael Meldgaard, Jens Zimmer, Iñigo Azcoitia, Robert Graham Quinton Leslie, Frederik Dagnaes-Hansen, and Bente Finsen Population Control of Resident and Immigrant Microglia by Mitosis and Apoptosis Am J Pathol 2007 171: 617-631. First published online June 28, 2007; doi:10.2353/ajpath.2007.061044 [Abstract] [Full Text] [PDF]   Steven M. Jay, Eleni Skokos, Farah Laiwalla, Marie-Marthe Krady, and Themis R. Kyriakides Foreign Body Giant Cell Formation Is Preceded by Lamellipodia Formation and Can Be Attenuated by Inhibition of Rac1 Activation Am J Pathol 2007 171: 632-640. First published online June 7, 2007; doi:10.2353/ajpath.2007.061213 [Abstract] [Full Text] [PDF] Supplemental Material   Luca Fabris, Massimiliano Cadamuro, Maria Guido, Carlo Spirli, Romina Fiorotto, Michele Colledan, Giuliano Torre, Daniele Alberti, Aurelio Sonzogni, Lajos Okolicsanyi, and Mario Strazzabosco Analysis of Liver Repair Mechanisms in Alagille Syndrome and Biliary Atresia Reveals a Role for Notch Signaling Am J Pathol 2007 171: 641-653. First published online June 28, 2007; doi:10.2353/ajpath.2007.070073 [Abstract] [Full Text] [PDF]

Tumorigenesis and Neoplastic Progression: Ugur Özbek, Ayten Kandilci, Sjozef van Baal, Jacqueline Bonten, Kelli Boyd, Patrick Franken, Riccardo Fodde, and Gerard C. Grosveld SET-CAN, the Product of the t(9;9) in Acute Undifferentiated Leukemia, Causes Expansion of Early Hematopoietic Progenitors and Hyperproliferation of Stomach Mucosa in Transgenic Mice Am J Pathol 2007 171: 654-666. First published online June 14, 2007; doi:10.2353/ajpath.2007.060934 [Abstract] [Full Text] [PDF]   Zhi Hong Lu, Jason D. Wright, Brian Belt, Robert D. Cardiff, and Jeffrey M. Arbeit Hypoxia-Inducible Factor-1 Facilitates Cervical Cancer Progression in Human Papillomavirus Type 16 Transgenic Mice Am J Pathol 2007 171: 667-681. First published online June 28, 2007; doi:10.2353/ajpath.2007.061138 [Abstract] [Full Text] [PDF] Supplemental Material   Mika Suzuki, Evangeline Mose, Christine Galloy, and David Tarin Osteopontin Gene Expression Determines Spontaneous Metastatic Performance of Orthotopic Human Breast Cancer Xenografts Am J Pathol 2007 171: 682-692. First published online July 9, 2007; doi:10.2353/ajpath.2007.070232 [Abstract] [Full Text] [PDF]

Vascular Biology, Atherosclerosis and Endothelium Biology: Matthew E. Kutcher, Alexey Y. Kolyada, Howard K. Surks, and Ira M. Herman Pericyte Rho GTPase Mediates Both Pericyte Contractile Phenotype and Capillary Endothelial Growth State Am J Pathol 2007 171: 693-701. First published online June 7, 2007; doi:10.2353/ajpath.2007.070102 [Abstract] [Full Text] [PDF]   Tero A.H. Järvinen and Erkki Ruoslahti Molecular Changes in the Vasculature of Injured Tissues Am J Pathol 2007 171: 702-711. First published online June 28, 2007; doi:10.2353/ajpath.2007.061251 [Abstract] [Full Text] [PDF] Supplemental Material

Correspondence: Anna Alisi, Valerio Nobili, Kohji Otogawa, and Norifumi Kawada Molecular Pathogenesis of Nonalcoholic Steatohepatitis: Today and Tomorrow Am J Pathol 2007 171: 712-713. First published online June 14, 2007; doi:10.2353/ajpath.2007.070463 [Full Text] [PDF]

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