Review Article: Elin S. Mortensen, Kristin A. Fenton, and Ole P. Rekvig Lupus Nephritis: The Central Role of Nucleosomes Revealed Am J Pathol 2008 172: 275-283. First published online January 10, 2008; doi:10.2353/ajpath.2008.070563 [Abstract] [Full Text] [PDF]

Commentaries: Charleen T. Chu Eaten Alive: Autophagy and Neuronal Cell Death after Hypoxia-Ischemia Am J Pathol 2008 172: 284-287. First published online January 17, 2008; doi:10.2353/ajpath.2008.071064 [Abstract] [Full Text] [PDF]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Neil C. Henderson, Alison C. Mackinnon, Sarah L. Farnworth, Tiina Kipari, Christopher Haslett, John P. Iredale, Fu-Tong Liu, Jeremy Hughes, and Tariq Sethi Galectin-3 Expression and Secretion Links Macrophages to the Promotion of Renal Fibrosis Am J Pathol 2008 172: 288-298. First published online January 17, 2008; doi:10.2353/ajpath.2008.070726 [Abstract] [Full Text] [PDF]   Yingjian Li, Young Sun Kang, Chunsun Dai, Lawrence P. Kiss, Xiaoyan Wen, and Youhua Liu Epithelial-to-Mesenchymal Transition Is a Potential Pathway Leading to Podocyte Dysfunction and Proteinuria Am J Pathol 2008 172: 299-308. First published online January 17, 2008; doi:10.2353/ajpath.2008.070057 [Abstract] [Full Text] [PDF]   Keren Borensztajn, Jurriën Stiekema, Sebastiaan Nijmeijer, Pieter H. Reitsma, Maikel P. Peppelenbosch, and C. Arnold Spek Factor Xa Stimulates Proinflammatory and Profibrotic Responses in Fibroblasts via Protease-Activated Receptor-2 Activation Am J Pathol 2008 172: 309-320. First published online January 17, 2008; doi:10.2353/ajpath.2008.070347 [Abstract] [Full Text] [PDF] Supplemental Material

Epithelial and Mesenchymal Cell Biology: Domenico Alvaro, Paolo Onori, Gianfranco Alpini, Antonio Franchitto, Douglas M. Jefferson, Alessia Torrice, Vincenzo Cardinale, Fabrizio Stefanelli, Maria Grazia Mancino, Mario Strazzabosco, Mario Angelico, Adolfo Attili, and Eugenio Gaudio Morphological and Functional Features of Hepatic Cyst Epithelium in Autosomal Dominant Polycystic Kidney Disease Am J Pathol 2008 172: 321-332. First published online January 17, 2008; doi:10.2353/ajpath.2008.070293 [Abstract] [Full Text] [PDF]   Kazuhiro Nakamura, Taku Sato, Akiko Ohashi, Hiromichi Tsurui, and Hiroyuki Hasegawa Role of a Serotonin Precursor in Development of Gut Microvilli Am J Pathol 2008 172: 333-344. First published online January 17, 2008; doi:10.2353/ajpath.2008.070358 [Abstract] [Full Text] [PDF]

Growth Factors, Cytokines, Cell Cycle Molecules: Caterina Bianco, Luigi Strizzi, Mario Mancino, Kazuhide Watanabe, Monica Gonzales, Shin Hamada, Ahmed Raafat, Lawson Sahlah, Cindy Chang, Federica Sotgia, Nicola Normanno, Michael Lisanti, and David S. Salomon Regulation of Cripto-1 Signaling and Biological Activity by Caveolin-1 in Mammary Epithelial Cells Am J Pathol 2008 172: 345-357. First published online January 17, 2008; doi:10.2353/ajpath.2008.070696 [Abstract] [Full Text] [PDF]   Toshio Kuwai, Toru Nakamura, Sun-Jin Kim, Takamitsu Sasaki, Yasuhiko Kitadai, Robert R. Langley, Dominic Fan, Stanley R. Hamilton, and Isaiah J. Fidler Intratumoral Heterogeneity for Expression of Tyrosine Kinase Growth Factor Receptors in Human Colon Cancer Surgical Specimens and Orthotopic Tumors Am J Pathol 2008 172: 358-366. First published online January 17, 2008; doi:10.2353/ajpath.2008.070625 [Abstract] [Full Text] [PDF]

Immunopathology and Infectious Disease: Mira Choi, Birgit Salanova, Susanne Rolle, Maren Wellner, Wolfgang Schneider, Friedrich C. Luft, and Ralph Kettritz Short-Term Heat Exposure Inhibits Inflammation by Abrogating Recruitment of and Nuclear Factor-B Activation in Neutrophils Exposed to Chemotactic Cytokines Am J Pathol 2008 172: 367-777. First published online January 10, 2008; doi:10.2353/ajpath.2008.070532 [Abstract] [Full Text] [PDF]   Lyn Hillyer, Charlene Whitley, Amy Olver, Michelle Webster, Tessa Steevels, and Bill Woodward Adoptively Transferred Dendritic Cells Restore Primary Cell-Mediated Inflammatory Competence to Acutely Malnourished Weanling Mice Am J Pathol 2008 172: 378-385. First published online January 17, 2008; doi:10.2353/ajpath.2008.070456 [Abstract] [Full Text] [PDF]   Matthew A. Schaller, Lara E. Kallal, and Nicholas W. Lukacs A Key Role for CC Chemokine Receptor 1 in T-Cell-Mediated Respiratory Inflammation Am J Pathol 2008 172: 386-394. First published online January 17, 2008; doi:10.2353/ajpath.2008.070537 [Abstract] [Full Text] [PDF]   Sarah L. Farnworth, Neil C. Henderson, Alison C. MacKinnon, Kirsten M. Atkinson, Tom Wilkinson, Kevin Dhaliwal, Katsutoshi Hayashi, A. John Simpson, Adriano G. Rossi, Christopher Haslett, and Tariq Sethi Galectin-3 Reduces the Severity of Pneumococcal Pneumonia by Augmenting Neutrophil Function Am J Pathol 2008 172: 395-405. First published online January 17, 2008; doi:10.2353/ajpath.2008.070870 [Abstract] [Full Text] [PDF]

Molecular Pathogenesis of Genetic and Inherited Diseases: Ibrahim Malik, John Turk, David J. Mancuso, Laura Montier, Mary Wohltmann, David F. Wozniak, Robert E. Schmidt, Richard W. Gross, and Paul T. Kotzbauer Disrupted Membrane Homeostasis and Accumulation of Ubiquitinated Proteins in a Mouse Model of Infantile Neuroaxonal Dystrophy Caused by PLA2G6 Mutations Am J Pathol 2008 172: 406-416. First published online January 17, 2008; doi:10.2353/ajpath.2008.070823 [Abstract] [Full Text] [PDF]   Anna-Rachel Gallagher, Ernie L. Esquivel, Tiffany S. Briere, Xin Tian, Michihiro Mitobe, Luis F. Menezes, Glen S. Markowitz, Dhanpat Jain, Luiz F. Onuchic, and Stefan Somlo Biliary and Pancreatic Dysgenesis in Mice Harboring a Mutation in Pkhd1 Am J Pathol 2008 172: 417-429. First published online January 17, 2008; doi:10.2353/ajpath.2008.070381 [Abstract] [Full Text] [PDF] Supplemental Material

Musculoskeletal Pathology: Larry J. Suva, Eric Hartman, Joshua D. Dilley, Susan Russell, Nisreen S. Akel, Robert A. Skinner, William R. Hogue, Ulrich Budde, Kottayil I. Varughese, Taisuke Kanaji, and Jerry Ware Platelet Dysfunction and a High Bone Mass Phenotype in a Murine Model of Platelet-Type von Willebrand Disease Am J Pathol 2008 172: 430-439. First published online January 10, 2008; doi:10.2353/ajpath.2008.070417 [Abstract] [Full Text] [PDF]   Kristen A. Johnson, Wei Yao, Nancy E. Lane, Philippe Naquet, and Robert A. Terkeltaub Vanin-1 Pantetheinase Drives Increased Chondrogenic Potential of Mesenchymal Precursors in ank/ank Mice Am J Pathol 2008 172: 440-453. First published online January 10, 2008; doi:10.2353/ajpath.2008.070753 [Abstract] [Full Text] [PDF] Supplemental Material

Neurobiology: Masato Koike, Masahiro Shibata, Masao Tadakoshi, Kunihito Gotoh, Masaaki Komatsu, Satoshi Waguri, Nobutaka Kawahara, Keisuke Kuida, Shigekazu Nagata, Eiki Kominami, Keiji Tanaka, and Yasuo Uchiyama Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury Am J Pathol 2008 172: 454-469. First published online January 10, 2008; doi:10.2353/ajpath.2008.070876 [Abstract] [Full Text] [PDF] Supplemental Material   David Muyllaert, Dick Terwel, Anna Kremer, Kristina Sennvik, Peter Borghgraef, Herman Devijver, Ilse Dewachter, and Fred Van Leuven Neurodegeneration and Neuroinflammation in cdk5/p25-Inducible Mice: A Model for Hippocampal Sclerosis and Neocortical Degeneration Am J Pathol 2008 172: 470-485. First published online January 17, 2008; doi:10.2353/ajpath.2008.070693 [Abstract] [Full Text] [PDF] Supplemental Material

Tumorigenesis and Neoplastic Progression: Sven Christian, Renate Winkler, Iris Helfrich, Anja M. Boos, Eva Besemfelder, Dirk Schadendorf, and Hellmut G. Augustin Endosialin (Tem1) Is a Marker of Tumor-Associated Myofibroblasts and Tumor Vessel-Associated Mural Cells Am J Pathol 2008 172: 486-494. First published online January 10, 2008; doi:10.2353/ajpath.2008.070623 [Abstract] [Full Text] [PDF]   Ron Tongbai, Gila Idelman, Silje H. Nordgard, Wenwu Cui, Jonathan L. Jacobs, Cynthia M. Haggerty, Stephen J. Chanock, Anne-Lise Børresen-Dale, Gary Livingston, Patrick Shaunessy, Chih-Hung Chiang, Vessela N. Kristensen, Sven Bilke, and Kevin Gardner Transcriptional Networks Inferred from Molecular Signatures of Breast Cancer Am J Pathol 2008 172: 495-509. First published online January 10, 2008; doi:10.2353/ajpath.2008.061079 [Abstract] [Full Text] [PDF] Supplemental Material   Burkhard Hirsch, Michael Hummel, Stefan Bentink, Fariba Fouladi, Rainer Spang, Raphael Zollinger, Harald Stein, and Horst Dürkop CD30-Induced Signaling Is Absent in Hodgkin’s Cells but Present in Anaplastic Large Cell Lymphoma Cells Am J Pathol 2008 172: 510-520. First published online January 10, 2008; doi:10.2353/ajpath.2008.070858 [Abstract] [Full Text] [PDF] Supplemental Material

Vascular Biology, Atherosclerosis and Endothelium Biology: Masaru Yamamoto, Servio H. Ramirez, Shinji Sato, Tomomi Kiyota, Ronald L. Cerny, Kozo Kaibuchi, Yuri Persidsky, and Tsuneya Ikezu Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells Am J Pathol 2008 172: 521-533. First published online January 10, 2008; doi:10.2353/ajpath.2008.070076 [Abstract] [Full Text] [PDF]   Christian M. Becker, Nadine Rohwer, Tae Funakoshi, Thorsten Cramer, Wanja Bernhardt, Amy Birsner, Judah Folkman, and Robert J. D’Amato 2-Methoxyestradiol Inhibits Hypoxia-Inducible Factor-1 and Suppresses Growth of Lesions in a Mouse Model of Endometriosis Am J Pathol 2008 172: 534-544. First published online January 17, 2008; doi:10.2353/ajpath.2008.061244 [Abstract] [Full Text] [PDF] Supplemental Material   Victor L. Thijssen, Sarah Hulsmans, and Arjan W. Griffioen The Galectin Profile of the Endothelium: Altered Expression and Localization in Activated and Tumor Endothelial Cells Am J Pathol 2008 172: 545-553. First published online January 17, 2008; doi:10.2353/ajpath.2008.070938 [Abstract] [Full Text] [PDF]

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