Reviews: Lorenzo Montanaro, Davide Treré, and Massimo Derenzini Nucleolus, Ribosomes, and Cancer Am J Pathol 2008 173: 301-310. First published online June 26, 2008; doi:10.2353/ajpath.2008.070752 [Abstract] [Full Text] [PDF]

Commentaries: Christopher W.G. Redman The Endoplasmic Reticulum Stress of Placental Impoverishment Am J Pathol 2008 173: 311-314. ; doi: 10.2353/ajpath.2008.080412 [Abstract] [Full Text] [PDF]

Regular Articles:

Cardiovascular, Pulmonary and Renal Pathology: Klaas Koop, Michael Eikmans, Markus Wehland, Hans Baelde, Daphne Ijpelaar, Reinhold Kreutz, Hiroshi Kawachi, Dontscho Kerjaschki, Emile de Heer, and Jan Anthonie Bruijn Selective Loss of Podoplanin Protein Expression Accompanies Proteinuria and Precedes Alterations in Podocyte Morphology in a Spontaneous Proteinuric Rat Model Am J Pathol 2008 173: 315-326. First published online July 3, 2008; doi:10.2353/ajpath.2008.080063 [Abstract] [Full Text] [PDF]   Weijing Cai, John C. He, Li Zhu, Xue Chen, Feng Zheng, Gary E. Striker, and Helen Vlassara Oral Glycotoxins Determine the Effects of Calorie Restriction on Oxidant Stress, Age-Related Diseases, and Lifespan Am J Pathol 2008 173: 327-336. First published online July 3, 2008; doi:10.2353/ajpath.2008.080152 [Abstract] [Full Text] [PDF]   Ling Lin, Zhihong Zhou, Liang Zheng, Sean Alber, Simon Watkins, Prabir Ray, Naftali Kaminski, Yingze Zhang, and Danielle Morse Cross Talk between Id1 and Its Interactive Protein Dril1 Mediate Fibroblast Responses to Transforming Growth Factor-β in Pulmonary Fibrosis Am J Pathol 2008 173: 337-346. First published online June 26, 2008; doi:10.2353/ajpath.2008.070915 [Abstract] [Full Text] [PDF]   Alice Bickerstaff, Ronald Pelletier, Jiao-Jing Wang, Gyongyi Nadasdy, Nicholas DiPaola, Charles Orosz, Anjali Satoskar, Gregg Hadley, and Tibor Nadasdy An Experimental Model of Acute Humoral Rejection of Renal Allografts Associated with Concomitant Cellular Rejection Am J Pathol 2008 173: 347-357. First published online June 26, 2008; doi:10.2353/ajpath.2008.070391 [Abstract] [Full Text] [PDF]   Xian Wu Cheng, Toyoaki Murohara, Masafumi Kuzuya, Hideo Izawa, Takeshi Sasaki, Koji Obata, Kohzo Nagata, Takao Nishizawa, Masakazu Kobayashi, Takashi Yamada, Weon Kim, Kohji Sato, Guo-Ping Shi, Kenji Okumura, and Mitsuhiro Yokota Superoxide-Dependent Cathepsin Activation Is Associated with Hypertensive Myocardial Remodeling and Represents a Target for Angiotensin II Type 1 Receptor Blocker Treatment Am J Pathol 2008 173: 358-369. First published online June 26, 2008; doi:10.2353/ajpath.2008.071126 [Abstract] [Full Text] [PDF] Supplemental Material

Cell Injury, Repair, Aging and Apoptosis: Anne M. Cataldo, Paul M. Mathews, Anne Boyer Boiteau, Linda C. Hassinger, Corrinne M. Peterhoff, Ying Jiang, Kerry Mullaney, Rachael L. Neve, Jean Gruenberg, and Ralph A. Nixon Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology: Accelerated Endocytosis Promotes Late Endocytic Defects Am J Pathol 2008 173: 370-384. First published online June 5, 2008; doi:10.2353/ajpath.2008.071053 [Abstract] [Full Text] [PDF] Supplemental Material

Gastrointestinal, Hepatobiliary and Pancreatic Pathology: Mary F. Walsh, Dinakar R. Ampasala, James Hatfield, Richard Vander Heide, Silke Suer, Arun K. Rishi, and Marc D. Basson Transforming Growth Factor-β Stimulates Intestinal Epithelial Focal Adhesion Kinase Synthesis via Smad- and p38-Dependent Mechanisms Am J Pathol 2008 173: 385-399. First published online June 26, 2008; doi:10.2353/ajpath.2008.070729 [Abstract] [Full Text] [PDF]   Hon-Wai Koon, Dezheng Zhao, Hua Xu, Collin Bowe, Alan Moss, Mary P. Moyer, and Charalabos Pothoulakis Substance P-Mediated Expression of the Pro-Angiogenic Factor CCN1 Modulates the Course of Colitis Am J Pathol 2008 173: 400-410. First published online July 3, 2008; doi:10.2353/ajpath.2008.080222 [Abstract] [Full Text] [PDF] Supplemental Material

Immunopathology and Infectious Disease: Wassim Elyaman, Pia Kivisäkk, Jay Reddy, Tanuja Chitnis, Khadir Raddassi, Jaime Imitola, Elizabeth Bradshaw, Vijay K. Kuchroo, Hideo Yagita, Mohamed H. Sayegh, and Samia J. Khoury Distinct Functions of Autoreactive Memory and Effector CD4+ T Cells in Experimental Autoimmune Encephalomyelitis Am J Pathol 2008 173: 411-422. First published online June 26, 2008; doi:10.2353/ajpath.2008.080142 [Abstract] [Full Text] [PDF] Supplemental Material   Kely C. Coltri, Leandro L. Oliveira, Camila F. Pinzan, Patrícia E. Vendruscolo, Roberto Martinez, Maria Helena Goldman, Ademilson Panunto-Castelo, and Maria-Cristina Roque-Barreira Therapeutic Administration of KM+ Lectin Protects Mice Against Paracoccidioides brasiliensis Infection via Interleukin-12 Production in a Toll-Like Receptor 2-Dependent Mechanism Am J Pathol 2008 173: 423-432. First published online July 3, 2008; doi:10.2353/ajpath.2008.080126 [Abstract] [Full Text] [PDF]

Metabolic, Endocrine and Genitourinary Pathobiology: Chih-Chao Hsu, Chun-Wun Lu, Bu-Miin Huang, Meng-Hsing Wu, and Shaw-Jenq Tsai Cyclic Adenosine 3',5'-Monophosphate Response Element-Binding Protein and CCAAT/Enhancer-Binding Protein Mediate Prostaglandin E2-Induced Steroidogenic Acute Regulatory Protein Expression in Endometriotic Stromal Cells Am J Pathol 2008 173: 433-441. First published online June 26, 2008; doi:10.2353/ajpath.2008.080199 [Abstract] [Full Text] [PDF]   Enrica Favaro, Ilaria Miceli, Benedetta Bussolati, Michel Schimitt-Ney, Paolo Cavallo Perin, Giovanni Camussi, and Maria M. Zanone Hyperglycemia Induces Apoptosis of Human Pancreatic Islet Endothelial Cells: Effects of Pravastatin on the Akt Survival Pathway Am J Pathol 2008 173: 442-450. First published online July 3, 2008; doi:10.2353/ajpath.2008.080238 [Abstract] [Full Text] [PDF]   Hong-wa Yung, Stefania Calabrese, Debby Hynx, Brian A. Hemmings, Irene Cetin, D. Stephen Charnock-Jones, and Graham J. Burton Evidence of Placental Translation Inhibition and Endoplasmic Reticulum Stress in the Etiology of Human Intrauterine Growth Restriction Am J Pathol 2008 173: 451-462. First published online June 26, 2008; doi:10.2353/ajpath.2008.071193 [Abstract] [Full Text] [PDF]   Zhuo OuYang, Yasushi Hirota, Yutaka Osuga, Kahori Hamasaki, Akiko Hasegawa, Toshiki Tajima, Tetsuya Hirata, Kaori Koga, Osamu Yoshino, Miyuki Harada, Yuri Takemura, Emi Nose, Tetsu Yano, and Yuji Taketani Interleukin-4 Stimulates Proliferation of Endometriotic Stromal Cells Am J Pathol 2008 173: 463-469. First published online July 3, 2008; doi:10.2353/ajpath.2008.071044 [Abstract] [Full Text] [PDF]

Neurobiology: Xinglong Wang, Bo Su, Hisashi Fujioka, and Xiongwei Zhu Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer’s Disease Patients Am J Pathol 2008 173: 470-482. First published online July 3, 2008; doi:10.2353/ajpath.2008.071208 [Abstract] [Full Text] [PDF] Supplemental Material   Gregory D. Van Vickle, Chera L. Esh, Ian D. Daugs, Tyler A. Kokjohn, Walter M. Kalback, R. Lyle Patton, Dean C. Luehrs, Douglas G. Walker, Lih-Fen Lue, Thomas G. Beach, Judianne Davis, William E. Van Nostrand, Eduardo M. Castaño, and Alex E. Roher Tg-SwDI Transgenic Mice Exhibit Novel Alterations in AβPP Processing, Aβ Degradation, and Resilient Amyloid Angiopathy Am J Pathol 2008 173: 483-493. First published online July 3, 2008; doi:10.2353/ajpath.2008.071191 [Abstract] [Full Text] [PDF]

Stem Cells, Tissue Engineering and Hematopoietic Elements: Wataru Hashimoto, Ryo Sudo, Kazutomo Fukasawa, Mariko Ikeda, Toshihiro Mitaka, and Kazuo Tanishita Ductular Network Formation by Rat Biliary Epithelial Cells in the Dynamical Culture with Collagen Gel and Dimethylsulfoxide Stimulation Am J Pathol 2008 173: 494-506. First published online June 26, 2008; doi:10.2353/ajpath.2008.071024 [Abstract] [Full Text] [PDF]   John C. Gomez, Jindrich Soltys, Keiichi Okano, Mary C. Dinauer, and Claire M. Doerschuk The Role of Rac2 in Regulating Neutrophil Production in the Bone Marrow and Circulating Neutrophil Counts Am J Pathol 2008 173: 507-517. First published online June 26, 2008; doi:10.2353/ajpath.2008.071059 [Abstract] [Full Text] [PDF]

Tumorigenesis and Neoplastic Progression: Sung Koo Kang, Young Kwang Chae, Janghee Woo, Myoung Sook Kim, Jong Chul Park, Juna Lee, Jean Charles Soria, Se Jin Jang, David Sidransky, and Chulso Moon Role of Human Aquaporin 5 In Colorectal Carcinogenesis Am J Pathol 2008 173: 518-525. First published online June 26, 2008; doi:10.2353/ajpath.2008.071198 [Abstract] [Full Text] [PDF]   Everardo Macias, Paula L. Miliani de Marval, Adriana De Siervi, Claudio J. Conti, Adrian M. Senderowicz, and Marcelo L. Rodriguez-Puebla CDK2 Activation in Mouse Epidermis Induces Keratinocyte Proliferation but Does Not Affect Skin Tumor Development Am J Pathol 2008 173: 526-535. First published online July 3, 2008; doi:10.2353/ajpath.2008.071124 [Abstract] [Full Text] [PDF]   Esra A. Akbay, Cristina M. Contreras, Samanthi A. Perera, James P. Sullivan, Russell R. Broaddus, John O. Schorge, Raheela Ashfaq, Hossein Saboorian, Kwok-Kin Wong, and Diego H. Castrillon Differential Roles of Telomere Attrition in Type I and II Endometrial Carcinogenesis Am J Pathol 2008 173: 536-544. First published online July 3, 2008; doi:10.2353/ajpath.2008.071179 [Abstract] [Full Text] [PDF]   David Zagzag, Mine Esencay, Olga Mendez, Herman Yee, Iva Smirnova, Yuanyuan Huang, Luis Chiriboga, Eugene Lukyanov, Mengling Liu, and Elizabeth W. Newcomb Hypoxia- and Vascular Endothelial Growth Factor-Induced Stromal Cell-Derived Factor-1/CXCR4 Expression in Glioblastomas: One Plausible Explanation of Scherer’s Structures Am J Pathol 2008 173: 545-560. First published online July 3, 2008; doi:10.2353/ajpath.2008.071197 [Abstract] [Full Text] [PDF]   Yi Xiao, Yin Ye, Kurtis Yearsley, Susie Jones, and Sanford H. Barsky The Lymphovascular Embolus of Inflammatory Breast Cancer Expresses a Stem Cell-Like Phenotype Am J Pathol 2008 173: 561-574. First published online July 3, 2008; doi:10.2353/ajpath.2008.071214 [Abstract] [Full Text] [PDF]

Vascular Biology, Atherosclerosis and Endothelium Biology: Jenilyn J. Virrey, Shengxi Guan, Wei Li, Axel H. Schönthal, Thomas C. Chen, and Florence M. Hofman Increased Survivin Expression Confers Chemoresistance to Tumor-Associated Endothelial Cells Am J Pathol 2008 173: 575-585. First published online July 3, 2008; doi:10.2353/ajpath.2008.071079 [Abstract] [Full Text] [PDF] Supplemental Material   Nadja Erika Banziger-Tobler, Cornelia Halin, Kentaro Kajiya, and Michael Detmar Growth Hormone Promotes Lymphangiogenesis Am J Pathol 2008 173: 586-597. First published online June 26, 2008; doi:10.2353/ajpath.2008.080060 [Abstract] [Full Text] [PDF]

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