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On the Cover

Cover image volume 188, Issue 10

October 2018

Volume 188, Issue 10

COLX/Wnt Reporter Activity during Long Bone Healing
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Journal of Molecular Diagnostics

Journal Metrics

2017 Impact Factor: 4.069
5-Year Impact Factor: 4.583
Eigenfactor: 0.03431

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© 2017 Journal Citation Report
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Publishing Information

The American Journal of Pathology is the official journal for The American Society for Investigative Pathology (ASIP).

Current Issue

October 2018
Volume 188, Issue 10

This Month in AJP
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Editor's Choice

Metabolic, Endocrine, and Genitourinary Pathobiology

Expanding upon the Human Myometrial Stem Cell Hypothesis and the Role of Race, Hormones, Age, and Parity in a Profibroid Environment

Vascular Biology, Atherosclerosis, and Endothelium Biology

Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability

AJP in the News

AJP in the News

A potential new way to treat some of the most common blinding diseases

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Issue Highlights

Ascending Vaginal Infection Using Bioluminescent Bacteria Evokes Intrauterine Inflammation, Preterm Birth, and Neonatal Brain Injury in Pregnant Mice

DOI: https://doi.org/10.1016/j.ajpath.2018.06.016

Open Access

Bioluminescent bacteria may help study intrauterine infection during pregnancy, and related outcomes.

DNA Methylation Reduces the Yes-Associated Protein 1/WW Domain Containing Transcription Regulator 1 Pathway and Prevents Pathologic Remodeling during Bladder Obstruction by Limiting Expression of BDNF

DOI: https://doi.org/10.1016/j.ajpath.2018.06.024

BDNF expression affects phenotypic changes in smooth muscle following bladder obstruction.

Expanding upon the Human Myometrial Stem Cell Hypothesis and the Role of Race, Hormones, Age, and Parity in a Profibroid Environment

DOI: https://doi.org/10.1016/j.ajpath.2018.06.023

The expanded myometrial stem cell population may contribute to uterine fibroid prevalence and burden.

Amyloid Precursor Protein Overexpression in Down Syndrome Trophoblast Reduces Cell Invasiveness and Interferes with Syncytialization

DOI: https://doi.org/10.1016/j.ajpath.2018.07.004

Study reveals mechanisms behind abnormal placental changes associated with Down syndrome fetuses.

Removal of Pre-Existing Periodontal Inflammatory Condition before Tooth Extraction Ameliorates Medication-Related Osteonecrosis of the Jaw–Like Lesion in Mice

DOI: https://doi.org/10.1016/j.ajpath.2018.06.019

Periodontal disease may promote osteonecrosis of the jaw following tooth extraction in the presence of currently prescribed drugs.

Articles in Press
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Abstract Image

Hypertension enhances advanced atherosclerosis and induces cardiac death in Watanabe heritable hyperlipidemic rabbits

Full length article

DOI: https://doi.org/10.1016/j.ajpath.2018.08.007

Published online: September 21, 2018

Abstract Image

Expression of Lrig1, a negative regulator of EGFR, is dynamically altered during different stages of gastric carcinogenesis

Full length article

DOI: https://doi.org/10.1016/j.ajpath.2018.08.006

Published online: September 21, 2018

Abstract Image

Characterization of a clival chordoma xenograft model reveals tumor genomic instability

Full length article

DOI: https://doi.org/10.1016/j.ajpath.2018.08.004

Published online: September 21, 2018

Abstract Image

Loss Of Prolyl-Hydroxylase 1 Protects Against Biliary Fibrosis Via Attenuated Activation Of Hepatic Stellate Cells

Full length article

DOI: https://doi.org/10.1016/j.ajpath.2018.08.003

Published online: September 21, 2018

Abstract Image

Angiopoietin-Like Protein 8 Is a Novel Vitamin D Receptor Target Gene Involved in Non-Alcoholic Fatty Liver Pathogenesis

Full length article

DOI: https://doi.org/10.1016/j.ajpath.2018.07.028

Published online: September 21, 2018

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Late Disseminated Lyme Disease: Associated Pathology and Spirochete Persistence Posttreatment in Rhesus Macaques

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DOI: https://doi.org/10.1016/j.ajpath.2017.11.005

Published online: December 11, 2017

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Breast Cancer Molecular Stratification: From Intrinsic Subtypes to Integrative Clusters

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DOI: https://doi.org/10.1016/j.ajpath.2017.04.022

Published online: July 18, 2017

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Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration

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DOI: https://doi.org/10.1016/j.ajpath.2015.06.001

Published online: June 25, 2015

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Koilocytosis: A Cooperative Interaction between the Human Papillomavirus E5 and E6 Oncoproteins

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DOI: https://doi.org/10.2353/ajpath.2008.080280

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Triple-Negative Breast Cancer: Next-Generation Sequencing for Target Identification

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DOI: https://doi.org/10.1016/j.ajpath.2017.05.018

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Audio/Video

A section of grossly normal human pancreas was immunolabeled with antibodies for CK19 and cleared. An atrophic lobule can be appreciated in the center of the cleared section.

Read the article: Immunolabeling of Cleared Human Pancreata Provides Insights into Three-Dimensional Pancreatic Anatomy and Pathology

Links of Interest

PISA 2018
October 20-22, 2018
Ann Arbor, Michigan
ASIP Annual Meeting at Experimental Biology 2019
April 6-10, 2019
Orlando, Florida
Path to Publish Newsletter
PathologyJobsToday Online Jobs Board
The Journal of Molecular Diagnostics

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