In the article entitled, “High Endothelial Venules Accelerate Naive T Cell Recruitment by Tumor Necrosis Factor-Mediated R-Ras Upregulation” (Volume 191, pages 396-414 of the February 2021 issue of The American Journal of Pathology; DOI: the authors have discovered an error in the primer sequences presented in the first paragraph of the Materials and Methods section: Mice and Tumor Model. The second sequence for Cre-recombination detection is incorrect and should be replaced.
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        • High Endothelial Venules Accelerate Naive T Cell Recruitment by Tumor Necrosis Factor-Mediated R-Ras Upregulation
          The American Journal of PathologyVol. 191Issue 2
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            Recruitment of naive T cells to lymph nodes is essential for the development of adaptive immunity. Upon pathogen infection, lymph nodes promptly increase the influx of naive T cells from the circulation in order to screen and prime the T cells. The precise contribution of the lymph node vasculature to the regulation of this process remains unclear. Here we show a role for the Ras GTPase, R-Ras, in the functional adaptation of high endothelial venules to increase naive T cell trafficking to the lymph nodes.
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