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Commentaries
83 Results
- CommentaryOpen Archive
Hodgkin Lymphoma Cells Have a Specific Long Noncoding RNA Expression Pattern
The American Journal of PathologyVol. 186Issue 9p2251–2253Published online: July 22, 2016- Simone Anfossi
- George A. Calin
Cited in Scopus: 1This commentary highlights the article by Tayari et al that suggests studying clinical implications of long noncoding RNAs as possible diagnostic and predictive biomarkers of Hodgkin lymphoma. - CommentaryOpen Archive
Antisense Sense in Osteoclasts
The American Journal of PathologyVol. 186Issue 9p2248–2250Published online: July 21, 2016- Teun J. de Vries
Cited in Scopus: 0This commentary highlights the article by Li et al that proposes regulating Wilm's tumor-1 antisense RNA to control pathological bone resorption. - CommentaryOpen Archive
Regulatory T Cells in Idiopathic Pulmonary Fibrosis: Too Much of a Good Thing?
The American Journal of PathologyVol. 186Issue 8p1978–1981Published online: June 23, 2016- Meagan W. Moore
- Erica L. Herzog
Cited in Scopus: 8This commentary highlights the article by Birjandi et al showing that alterations in regulatory T cells can exacerbate lung fibrosis. - CommentaryOpen Archive
Huntington Disease: A Disease of DNA Methylation or DNA Breaks?
The American Journal of PathologyVol. 186Issue 7p1750–1753Published online: May 21, 2016- Mélanie L. Ferlazzo
- Nicolas Foray
Cited in Scopus: 9This commentary highlights the article by Mollica et al that describes an interesting model for the clinical evolution of Huntington disease. - CommentaryOpen Archive
Mouse Osteoblasts Play a Crucial Role in the Immune System
The American Journal of PathologyVol. 186Issue 5p1078–1080Published online: March 16, 2016- Shigeru Kotake
- Yuki Nanke
Cited in Scopus: 1This commentary highlights the article by Tu et al describing mechanisms in immune-mediated arthritis that may propel strategies to treat diseases involving the bone and immune system. - CommentaryOpen Archive
Synthetic Prions Provide Clues for Understanding Prion Diseases
The American Journal of PathologyVol. 186Issue 4p761–764Published online: February 5, 2016- Thibaut Imberdis
- David A. Harris
Cited in Scopus: 3This Commentary highlights the article by Makarava et al that discusses the formation of synthetic prions and the role of substrate levels in their evolution. - CommentaryOpen Archive
Value of Autopsy Emphasized in the Case Report of a Single Patient with Middle East Respiratory Syndrome
The American Journal of PathologyVol. 186Issue 3p507–510Published online: December 24, 2015- David H. Walker
Cited in Scopus: 15This commentary highlights the article by Ng et al, emphasizing the need for autopsies to better model infectious diseases such as Middle East respiratory syndrome. - Commentary
Insights into Environmental Factors Impacting Celiac Disease: Microbiota Modulation of Disease Pathogenesis
The American Journal of PathologyVol. 185Issue 11p2864–2866Published online: September 21, 2015- Robin G. Lorenz
Cited in Scopus: 1This commentary highlights the article by Galipeau et al exploring the role of microbiota in modulating gluten immune response and celiac disease-like pathology in a humanized mouse model. - CommentaryOpen Archive
Stat5a/b in Prostate Cancer Metastasis
The American Journal of PathologyVol. 185Issue 9p2351–2353Published online: July 14, 2015- Allen C. Gao
- Yezi Zhu
Cited in Scopus: 3This commentary highlights the article by Talati et al that describes novel mechanisms promoting metastasis in prostate cancer. - CommentaryOpen Archive
Genomic Catastrophe and Neoplastic Transformation
The American Journal of PathologyVol. 185Issue 7p1846–1849Published in issue: July, 2015- William B. Coleman
Cited in Scopus: 0This commentary highlights the article by Zhou et al that describes an innovative experimental design that uncovered cell fusion in tumorigenesis. - CommentaryOpen Archive
A Road to Chronic Kidney Disease: Toward Glomerulosclerosis via Dendrin
The American Journal of PathologyVol. 185Issue 8p2072–2075Published online: June 8, 2015- Francesca Becherucci
- Elena Lazzeri
- Paola Romagnani
Cited in Scopus: 3This commentary highlights the article by Weins et al that describes a potential mechanism to delay the onset and progression of end-stage kidney disease. - CommentaryOpen Archive
Insights into End-Organ Injury in HIV Infection: Dynamics of Monocyte Trafficking to the Brain in SIV Encephalitis
The American Journal of PathologyVol. 185Issue 6p1548–1551Published online: May 8, 2015- Yuri Persidsky
Cited in Scopus: 1This commentary highlights the article by Nowlin et al, which explores the dynamic roles of macrophages in early and late central nervous system lentiviral disease. - CommentaryOpen Archive
Breaking the Barriers: New Role for Insulin-Like Growth Factor 1 Receptor in Vascular Permeability
The American Journal of PathologyVol. 185Issue 5p1198–1200Published online: March 6, 2015- Sandhya Xavier
Cited in Scopus: 0This commentary highlights the article by Liang et al that describes a critical role for insulin-like growth factor 1 receptor in the progression of chronic kidney disease. - CommentaryOpen Access
Lessons Learned About Prostatic Transformation from the Age-Related Methylation of 5α-Reductase Type 2 Gene
The American Journal of PathologyVol. 185Issue 3p614–616Published online: February 17, 2015- John T. Isaacs
Cited in Scopus: 3This commentary highlights the article by Ge et al, which proposes the use of methylation and expression of SRD5A2 as a gene signature to tailor therapies for prostatic diseases. - CommentaryOpen Access
ROCK and Rho: Promising Therapeutic Targets to Ameliorate Pulmonary Fibrosis
The American Journal of PathologyVol. 185Issue 4p909–912Published online: February 13, 2015- David W.H. Riches
- Donald S. Backos
- Elizabeth F. Redente
Cited in Scopus: 10This commentary highlights the article by Sisson et al, which establishes the importance of the myocardin-related transcription factor/serum response factor signaling pathway as a therapeutic target in the management of fibrotic lung disease. - CommentaryOpen Access
Why Do We Need a Nonhuman Primate Model of Smoking-Induced COPD?
The American Journal of PathologyVol. 185Issue 3p610–613Published online: January 7, 2015- Jeffrey L. Curtis
- Christine M. Freeman
Cited in Scopus: 3This Commentary highlights the article by Polverino et al, describing the development of a novel nonhuman primate model of cigarette smoke–induced chronic obstructive pulmonary disease. - CommentaryOpen Archive
Pulmonary Veno-Occlusive Disease: A Rare Cause of Pulmonary Hypertension
The American Journal of PathologyVol. 185Issue 2p302–304Published online: December 17, 2014- Kazuyuki Yahagi
- Renu Virmani
Cited in Scopus: 0This commentary highlights the article by Ranchoux and Günther, showing a cause-and-effect link between alkylating agents and pulmonary veno-occlusive disease. - CommentaryOpen Archive
The Role of SIRT1 in Cancer: The Saga Continues
The American Journal of PathologyVol. 185Issue 1p26–28Published online: November 17, 2014- Melissa J. Wilking
- Nihal Ahmad
Cited in Scopus: 29This Commentary highlights the article by Di Sante et al, which presents data supporting the status of SIRT1 as a tumor suppressor in prostate cancer. - CommentaryOpen Archive
Mitochondrial DNA Mutations and Cancer: Lessons from the Parathyroid
The American Journal of PathologyVol. 184Issue 11p2852–2854Published online: September 18, 2014- Konstantin Popadin
- Konstantin V. Gunbin
- Konstantin Khrapko
Cited in Scopus: 2This commentary highlights the article by Müller-Höcker et al, which provides a different view on the distribution and role of mtDNA mutations in oncocytic tumors. - CommentaryOpen Archive
Syndecan 4 Signaling and Intervertebral Disc Degeneration
The American Journal of PathologyVol. 184Issue 9p2371–2373Published in issue: September, 2014- Fackson Mwale
Cited in Scopus: 2This commentary highlights the article by Wang et al, exploring the regulatory relationship between matrix metalloproteinase-3 and syndecan 4 in disc degeneration. - CommentaryOpen Archive
Fusing Transcriptomics to Progressive Prostate Cancer
The American Journal of PathologyVol. 184Issue 10p2608–2610Published online: August 13, 2014- Masaya Jimbo
- Karen E. Knudsen
- Jonathan R. Brody
Cited in Scopus: 0This commentary highlights the article by Yu et al, describing a set of novel fusion transcripts strongly associated with prostate cancer prognosis. - Commentary
Genetic Control of Nerve Conduction Velocity May Influence Multiple Sclerosis Phenotype
The American Journal of PathologyVol. 184Issue 9p2369–2370Published online: August 12, 2014- Hans Lassmann
Cited in Scopus: 1This commentary highlights the article by Lemcke et al that reports a polymorphism in the Inpp4b gene, which is associated with increased risk of developing multiple sclerosis. - CommentaryOpen Archive
Exploiting Endogenous Anti-Inflammatory Pathways as a Therapeutic Approach to Multiorgan Inflammatory Disease
The American Journal of PathologyVol. 184Issue 8p2154–2155Published online: July 9, 2014- John L. Wallace
Cited in Scopus: 1This Commentary highlights the article by Montero-Melendez et al, revealing novel protective properties of endogenous melanocortin receptor 3 on periodontal status in health and disease and suggesting a new genus of anti-arthritic bone-sparing therapeutics. - CommentaryOpen Access
The Liver Is a Peculiar Organ When It Comes to Stem Cells
The American Journal of PathologyVol. 184Issue 5p1263–1267Published online: March 31, 2014- George K. Michalopoulos
Cited in Scopus: 25This Commentary highlights the article by Sekiya and Suzuki, detailing genetic lineage tracing to determine the origin of cells that form primitive ductules in a mouse model of chronic liver injury. - Commentary
The BRC Canopy: An Important Player in Bone Remodeling
The American Journal of PathologyVol. 184Issue 4p924–926Published online: February 24, 2014- Katherine Wesseling-Perry
Cited in Scopus: 6This Commentary highlights the article by Andersen et al, which describes structural changes in bone associated with increased bone resorption in osteoporotic post-menopausal women.