May 2023

Biomarkers, Genomics, Proteomics, and Gene Regulation

Transcriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFB1-TBXT Network
• Stefan C. Halvorsen,
• Yair Benita,
• Megan Hopton,
• ...
• Andrew E. Rosenberg,
• Francis J. Hornicek,
• Slim Sassi
Published online: February 16, 2023
p532-547
Open Access

Gastrointestinal, Hepatobiliary, and Pancreatic Pathology

TRPV1 Dysfunction Impairs Gastric Nitrergic Neuromuscular Relaxation in High-Fat Diet–Induced Diabetic Gastroparesis Mice
• Siyuan Xu,
• Shaochan Liang,
• Ying Pei,
• ...
• Bo Tan,
• Hongying Cao,
• Shaoju Guo
Published online: February 03, 2023
p548-557
Open Access

A Spatial Atlas of Wnt Receptors in Adult Mouse Liver
• Jenesis Gayden,
• Shikai Hu,
• Paul N. Joseph,
• ...
• Stephanie Puig,
• Satdarshan P. Monga,
• Zachary Freyberg
Published online: February 09, 2023
p558-566

Immunopathology and Infectious Diseases

Protein Kinase CK2 Promotes Proliferation, Abnormal Differentiation, and Proinflammatory Cytokine Production of Keratinocytes via Regulation of STAT3 and Akt Pathways in Psoriasis
• Wenjie Huang,
• Xuyu Zheng,
• Qi Huang,
• ...
• Yulian Hu,
• Wenchun Xu,
• Kun Huang
Published in issue: May 2023
p567-578

Machine Learning, Computational Pathology, and Biophysical Imaging

Tensor Decomposition of Largest Convolutional Eigenvalues Reveals Pathologic Predictive Power of RhoB in Rectal Cancer Biopsy
• Tuan D. Pham,
• Vinayakumar Ravi,
• Chuanwen Fan,
• Bin Luo,
• Xiao-Feng Sun
Published online: February 03, 2023
p579-590

Musculoskeletal Pathology

Circulating α-Klotho Counteracts Transforming Growth Factor-β–Induced Sarcopenia
• Yutaka Ohsawa,
• Hideaki Ohtsubo,
• Asami Munekane,
• ...
• Atsushi Hinohara,
• Masao Fukunaga,
• Yoshihide Sunada
Published online: February 09, 2023
p591-607

Tumorigenesis and Neoplastic Progression

Tumor-Derived Oxidative Stress Triggers Ovarian Follicle Loss in Breast Cancer
• Yongqi Wu,
• Jieqiong Huang,
• Hui Chen,
• ...
• Qingbing Zha,
• Gendie E. Lash,
• Ping Li
Published online: February 17, 2023
p608-623
Open Access

Protein Kinase D2 and D3 Promote Prostate Cancer Cell Bone Metastasis by Positively Regulating Runx2 in a MEK/ERK1/2–Dependent Manner
• Adhiraj Roy,
• Sahdeo Prasad,
• Yuzhou Chen,
• ...
• Yu Liu,
• Jinjun Zhao,
• Qiming Jane Wang
Published online: February 03, 2023
p624-637

Vascular Biology, Atherosclerosis, and Endothelium Biology

Genetic Deletion of FXR1 Reduces Intimal Hyperplasia and Induces Senescence in Vascular Smooth Muscle Cells
• Cali B. Corbett,
• Amanda St Paul,
• Tani Leigh,
• ...
• Satoru Eguchi,
• Dale S. Haines,
• Michael V. Autieri
Published in issue: May 2023
p638-653