October 2012

Animal Models

Epidermal Hyperplasia and Appendage Abnormalities in Mice Lacking CD109
• Shinji Mii,
• Yoshiki Murakumo,
• Naoya Asai,
• ...
• Sayaka Sobue,
• Masatoshi Ichihara,
• Masahide Takahashi
Published online: July 30, 2012
p1180-1189

A Novel Animal Model for Pseudoxanthoma Elasticum
The KK/HlJ Mouse
• Qiaoli Li,
• Annerose Berndt,
• Haitao Guo,
• John P. Sundberg,
• Jouni Uitto
Published online: July 30, 2012
p1190-1196

Soluble Human IL-1 Receptor Type 2 Inhibits Ectopic Endometrial Tissue Implantation and Growth
Identification of a Novel Potential Target for Endometriosis Treatment
• Khaled Khoufache,
• Patrick Kibangou Bondza,
• Noria Harir,
• ...
• Madeleine Lemyre,
• Warren Foster,
• Ali Akoum
Published online: July 30, 2012
p1197-1205

A Novel Mouse Model of Staphylococcus aureus Chronic Osteomyelitis That Closely Mimics the Human Infection
An Integrated View of Disease Pathogenesis
• Sarah A. Horst,
• Verena Hoerr,
• Andreas Beineke,
• ...
• Cornelius Faber,
• Bettina Löffler,
• Eva Medina
Published online: August 20, 2012
p1206-1214

Cardiovascular, Pulmonary, and Renal Pathology

The Receptor for Advanced Glycation End Products Is a Central Mediator of Asthma Pathogenesis
• Pavle S. Milutinovic,
• John F. Alcorn,
• Judson M. Englert,
• Lauren T. Crum,
• Tim D. Oury
Published online: August 13, 2012
p1215-1225

Pressure Overload Induces Early Morphological Changes in the Heart
• Colby A. Souders,
• Thomas K. Borg,
• Indroneal Banerjee,
• Troy A. Baudino
Published online: September 06, 2012
p1226-1235

Epithelial and Mesenchymal Cell Biology

Lysophosphatidic Acid Increases Proximal Tubule Cell Secretion of Profibrotic Cytokines PDGF-B and CTGF through LPA2- and Gαq-Mediated Rho and αvβ6 Integrin-Dependent Activation of TGF-β
• Hui Geng,
• Rongpei Lan,
• Prajjal K. Singha,
• ...
• Joel M. Weinberg,
• Pothana Saikumar,
• Manjeri A. Venkatachalam
Published online: August 13, 2012
p1236-1249


A RHAMM Mimetic Peptide Blocks Hyaluronan Signaling and Reduces Inflammation and Fibrogenesis in Excisional Skin Wounds
• Cornelia Tolg,
• Sara R. Hamilton,
• Ewa Zalinska,
• ...
• Mary K. Cowman,
• Jim B. McCarthy,
• Eva A. Turley
Published online: August 13, 2012
p1250-1270

Gastrointestinal, Hepatobiliary, and Pancreatic Pathology

XIAP as a Radioresistance Factor and Prognostic Marker for Radiotherapy in Human Rectal Adenocarcinoma
• Driffa Moussata,
• Souheila Amara,
• Bénazir Siddeek,
• ...
• Bernard Flourie,
• Mohamed Benahmed,
• Claire Mauduit
Published online: August 06, 2012
p1271-1278

Leptin Deficiency Contributes to the Pathogenesis of Alcoholic Fatty Liver Disease in Mice
• Xiaobing Tan,
• Xiuhua Sun,
• Qiong Li,
• ...
• Wei Jia,
• Craig J. McClain,
• Zhanxiang Zhou
Published online: July 30, 2012
p1279-1286

Therapeutic Administration of the Direct Thrombin Inhibitor Argatroban Reduces Hepatic Inflammation in Mice with Established Fatty Liver Disease
• Karen M. Kassel,
• Bradley P. Sullivan,
• Wei Cui,
• Bryan L. Copple,
• James P. Luyendyk
Published online: July 30, 2012
p1287-1295

Three-Dimensional Scaffolds Reduce Islet Amyloid Formation and Enhance Survival and Function of Cultured Human Islets
• Yun Zhang,
• Reza B. Jalili,
• Garth L. Warnock,
• Ziliang Ao,
• Lucy Marzban,
• Aziz Ghahary
Published online: August 20, 2012
p1296-1305

p53 Mediates TNF-Induced Epithelial Cell Apoptosis in IBD
• Tatiana Goretsky,
• Ramanarao Dirisina,
• Preetika Sinh,
• ...
• Hyunji Ryu,
• Rebecca B. Katzman,
• Terrence A. Barrett
Published online: August 06, 2012
p1306-1315

Prostaglandin Reductase 2 Modulates ROS-Mediated Cell Death and Tumor Transformation of Gastric Cancer Cells and Is Associated with Higher Mortality in Gastric Cancer Patients
• Emily Yun-Chia Chang,
• Shu-Huei Tsai,
• Chia-Tung Shun,
• ...
• Jia-Wei Chou,
• Shih-Yao Lin,
• Lee-Ming Chuang
Published in issue: October 2012
p1316-1326

Immunopathology and Infectious Diseases

Dendritic Cells Are Central Coordinators of the Host Immune Response to Staphylococcus aureus Bloodstream Infection
• Daniela Schindler,
• Maximiliano G. Gutierrez,
• Andreas Beineke,
• ...
• Simon Foster,
• Oliver Goldmann,
• Eva Medina
Published online: August 13, 2012
p1327-1337

Determination of Severity of Murine IgA Nephropathy by Glomerular Complement Activation by Aberrantly Glycosylated IgA and Immune Complexes
• Azusa Hashimoto,
• Yusuke Suzuki,
• Hitoshi Suzuki,
• ...
• Jan Novak,
• Hiroyuki Ohi,
• Yasuhiko Tomino
Published online: August 06, 2012
p1338-1347

Targeting Host Syntaxin-5 Preferentially Blocks Leishmania Parasitophorous Vacuole Development in Infected Cells and Limits Experimental Leishmania Infections
• Johnathan Canton,
• Peter E. Kima
Published online: August 13, 2012
p1348-1355

Virulence Factors Identified by Cryptococcus neoformans Mutant Screen Differentially Modulate Lung Immune Responses and Brain Dissemination
• Xiumiao He,
• Daniel M. Lyons,
• Dena L. Toffaletti,
• ...
• John J. Osterholzer,
• John R. Perfect,
• Michal A. Olszewski
Published online: July 30, 2012
p1356-1366

Molecular Pathogenesis of Genetic and Inherited Diseases

CFTR Is Involved in the Fine Tuning of Intracellular Redox Status
Physiological Implications in Cystic Fibrosis
• Christophe Duranton,
• Isabelle Rubera,
• Marc Cougnon,
• ...
• Abderrahman Chargui,
• Baharia Mograbi,
• Michel Tauc
Published online: July 30, 2012
p1367-1377

MutT Homolog-1 Attenuates Oxidative DNA Damage and Delays Photoreceptor Cell Death in Inherited Retinal Degeneration
• Yusuke Murakami,
• Yasuhiro Ikeda,
• Noriko Yoshida,
• ...
• Margherita Bignami,
• Yusaku Nakabeppu,
• Tatsuro Ishibashi
Published online: July 30, 2012
p1378-1386

Generation of Isogenic D4Z4 Contracted and Noncontracted Immortal Muscle Cell Clones from a Mosaic Patient
A Cellular Model for FSHD
• Yvonne D. Krom,
• Julie Dumonceaux,
• Kamel Mamchaoui,
• ...
• Vincent Mouly,
• Gillian S. Butler-Browne,
• Silvère M. van der Maarel
Published online: August 06, 2012
p1387-1401

Neurobiology

Antibodies to Gliomedin Cause Peripheral Demyelinating Neuropathy and the Dismantling of the Nodes of Ranvier
• Jérôme J. Devaux
Published online: August 13, 2012
p1402-1413

Glycogen Synthase Kinase 3β Inhibition Prevents Monocyte Migration across Brain Endothelial Cells via Rac1-GTPase Suppression and Down-Regulation of Active Integrin Conformation
• Slava Rom,
• Shongshan Fan,
• Nancy Reichenbach,
• Holly Dykstra,
• Servio H. Ramirez,
• Yuri Persidsky
Published online: August 06, 2012
p1414-1425

The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System
• Hwan-Ching Tai,
• Alberto Serrano-Pozo,
• Tadafumi Hashimoto,
• Matthew P. Frosch,
• Tara L. Spires-Jones,
• Bradley T. Hyman
Published online: August 06, 2012
p1426-1435

Tumorigenesis and Neoplastic Progression

Measurement of Aldehyde Dehydrogenase 1 Expression Defines a Group with Better Prognosis in Patients with Non-Small Cell Lung Cancer
• Anastasios Dimou,
• Veronique Neumeister,
• Seema Agarwal,
• Valsamo Anagnostou,
• Konstantinos Syrigos,
• David L. Rimm
Published online: August 08, 2012
p1436-1442

PAGE4 Positivity Is Associated with Attenuated AR Signaling and Predicts Patient Survival in Hormone-Naive Prostate Cancer
• Natalie Sampson,
• Christian Ruiz,
• Christoph Zenzmaier,
• Lukas Bubendorf,
• Peter Berger
Published online: August 13, 2012
p1443-1454

Vascular Biology, Atherosclerosis, and Endothelium Biology

Preeclampsia Is Associated with Alterations in DNA Methylation of Genes Involved in Collagen Metabolism
• Ahmad A. Mousa,
• Renato E. Cappello,
• Guadalupe Estrada-Gutierrez,
• ...
• Roberto Romero,
• Jerome F. Strauss III,
• Scott W. Walsh
Published online: August 06, 2012
p1455-1463

Adrenomedullin Inhibits Choroidal Neovascularization via CCL2 in the Retinal Pigment Epithelium
• Kentaro Yuda,
• Hidenori Takahashi,
• Tatsuya Inoue,
• ...
• Hiroyuki Aburatani,
• Ryozo Nagai,
• Yasuo Yanagi
Published online: July 30, 2012
p1464-1472

Circulating Microparticles from Patients with Obstructive Sleep Apnea Enhance Vascular Contraction
Mandatory Role of the Endothelium
• Simon Tual-Chalot,
• Keita Fatoumata,
• Pascaline Priou,
• ...
• Maria Carmen Martinez,
• Frédéric Gagnadoux,
• Ramaroson Andriantsitohaina
Published online: July 30, 2012
p1473-1482