December 2012

Animal Models

Lack of Tau Proteins Rescues Neuronal Cell Death and Decreases Amyloidogenic Processing of APP in APP/PS1 Mice
• Karelle Leroy,
• Kunie Ando,
• Vincent Laporte,
• ...
• Zehra Yilmaz,
• Jean-Noël Octave,
• Jean-Pierre Brion
Published online: October 01, 2012
p1928-1940

Nephrogenic Systemic Fibrosis
Evidence for Oxidative Stress and Bone Marrow–Derived Fibrocytes in Skin, Liver, and Heart Lesions Using a 5/6 Nephrectomy Rodent Model
• Brent Wagner,
• Chunyan Tan,
• Jeffrey L. Barnes,
• ...
• Thomas L. Davis,
• Yves Gorin,
• Fabio Jimenez
Published online: October 08, 2012
p1941-1952

Biophysical Imaging and Computational Biology

Spectral Discrimination of Cerebral Amyloid Lesions after Peripheral Application of Luminescent Conjugated Oligothiophenes
• Bettina M. Wegenast-Braun,
• Angelos Skodras,
• Gonca Bayraktar,
• ...
• K. Peter R. Nilsson,
• Christian Liebig,
• Mathias Jucker
Published online: October 08, 2012
p1953-1960

FT-IR Microspectroscopy of Mouse Colon Tissues
Insight into the Chemistry of Carcinogenesis and Diagnostic Potential
• Menashi A. Cohenford,
• SeungJin Lim,
• Chris Brown,
• ...
• Saroj Sigdel,
• Emily Beckelhimer,
• Basil Rigas
Published online: October 11, 2012
p1961-1968

Cardiovascular, Pulmonary, and Renal Pathology

Short-Term Akt Activation in Cardiac Muscle Cells Improves Contractile Function in Failing Hearts
• Ichiro Shiojima,
• Stephan Schiekofer,
• Jochen G. Schneider,
• ...
• Martin Andrassy,
• Gennaro Galasso,
• Kenneth Walsh
Published online: October 01, 2012
p1969-1976

Unfolded Protein Response Causes a Phenotypic Shift of Inflamed Glomerular Cells toward Redifferentiation through Dual Blockade of Akt and Smad Signaling Pathways
• Hisashi Johno,
• Shotaro Nakajima,
• Hironori Kato,
• ...
• Ryohei Katoh,
• Fujio Shimizu,
• Masanori Kitamura
Published online: October 01, 2012
p1977-1990

Kidney Proximal Tubular Epithelial-Specific Overexpression of Netrin-1 Suppresses Inflammation and Albuminuria through Suppression of COX-2-Mediated PGE2 Production in Streptozotocin-Induced Diabetic Mice
• Riyaz Mohamed,
• Calpurnia Jayakumar,
• Punithavathi V. Ranganathan,
• Vadivel Ganapathy,
• Ganesan Ramesh
Published online: October 04, 2012
p1991-2002

Loss of Semaphorin-Neuropilin-1 Signaling Causes Dysmorphic Vascularization Reminiscent of Alveolar Capillary Dysplasia
• Stephen Joza,
• Jinxia Wang,
• Emily Fox,
• Valerie Hillman,
• Cameron Ackerley,
• Martin Post
Published online: October 16, 2012
p2003-2017

BDNF/TrkB Signaling Augments Smooth Muscle Cell Proliferation in Pulmonary Hypertension
• Grazyna Kwapiszewska,
• Karolina Chwalek,
• Leigh M. Marsh,
• ...
• Norbert Weissmann,
• Oliver Eickelberg,
• Ludger Fink
Published online: October 10, 2012
p2018-2029

Myocyte Shape Regulates Lateral Registry of Sarcomeres and Contractility
• Po-Ling Kuo,
• Hyungsuk Lee,
• Mark-Anthony Bray,
• ...
• William J. Adams,
• Sean P. Sheehy,
• Kevin K. Parker
Published in issue: December 2012
p2030-2037

Interferon-γ Causes Cardiac Myocyte Atrophy via Selective Degradation of Myosin Heavy Chain in a Model of Chronic Myocarditis
• Pippa F. Cosper,
• Pamela A. Harvey,
• Leslie A. Leinwand
Published online: October 10, 2012
p2038-2046

Cell Injury, Repair, Aging, and Apoptosis

Aquaporin 3 Expression Is Up-Regulated by TGF-β1 in Rat Peritoneal Mesothelial Cells and Plays a Role in Wound Healing
• Hye-Myung Ryu,
• Eun-Joo Oh,
• Sun-Hee Park,
• ...
• Ho-Young Chung,
• Min Yoo,
• Yong-Lim Kim
Published online: October 05, 2012
p2047-2057

Reduced Innervation and Delayed Re-Innervation After Epithelial Wounding in Type 2 Diabetic Goto-Kakizaki Rats
• Feng Wang,
• Nan Gao,
• Jia Yin,
• Fu-Shin X. Yu
Published online: October 12, 2012
p2058-2066

Role of WNT/β-Catenin Signaling in Rejuvenating Myogenic Differentiation of Aged Mesenchymal Stem Cells from Cardiac Patients
• Keith R. Brunt,
• Yuemei Zhang,
• Anton Mihic,
• ...
• Richard D. Weisel,
• Terrence M. Yau,
• Ren-Ke Li
Published online: October 01, 2012
p2067-2078

DNA Methylation Plasticity of Human Adipose-Derived Stem Cells in Lineage Commitment
• María Berdasco,
• Consolación Melguizo,
• Jose Prados,
• ...
• Inma Zafra,
• Antonia Aranega,
• Manel Esteller
Published online: October 01, 2012
p2079-2093

Gastrointestinal, Hepatobiliary, and Pancreatic Pathology

Recovery of Mature Hepatocytic Phenotype following Bile Ductular Transdifferentiation of Rat Hepatocytes in Vitro
• Masayuki Sone,
• Yuji Nishikawa,
• Yasuharu Nagahama,
• ...
• Masayuki Yoshida,
• Toshihiro Sugiyama,
• Katsuhiko Enomoto
Published online: October 08, 2012
p2094-2104

Pancreatic STAT3 Protects Mice against Caerulein-Induced Pancreatitis via PAP1 Induction
• Minoru Shigekawa,
• Hayato Hikita,
• Takahiro Kodama,
• ...
• Kiyoshi Takeda,
• Shizuo Akira,
• Tetsuo Takehara
Published online: October 12, 2012
p2105-2113

Transgenic Expression of Interferon-γ in Mouse Stomach Leads to Inflammation, Metaplasia, and Dysplasia
• Li-Jyun Syu,
• Mohamad El-Zaatari,
• Kathryn A. Eaton,
• ...
• Juanita L. Merchant,
• Linda C. Samuelson,
• Andrzej A. Dlugosz
Published online: October 02, 2012
p2114-2125

Growth Factors, Cytokines, and Cell Cycle Molecules

The Hedgehog System Machinery Controls Transforming Growth Factor-β–Dependent Myofibroblastic Differentiation in Humans
Involvement in Idiopathic Pulmonary Fibrosis
• Natacha Cigna,
• Elika Farrokhi Moshai,
• Stéphanie Brayer,
• ...
• Paul Soler,
• Bruno Crestani,
• Arnaud A. Mailleux
Published online: October 01, 2012
p2126-2137

Abruption-Induced Preterm Delivery Is Associated with Thrombin-Mediated Functional Progesterone Withdrawal in Decidual Cells
• Charles J. Lockwood,
• Umit A. Kayisli,
• Carlos Stocco,
• ...
• Emre Vatandaslar,
• Lynn F. Buchwalder,
• Frederick Schatz
Published online: October 11, 2012
p2138-2148

Altered Decidual DC-SIGN⁺ Antigen-Presenting Cells and Impaired Regulatory T-Cell Induction in Preeclampsia
• Peter Hsu,
• Brigitte Santner-Nanan,
• Jane E. Dahlstrom,
• ...
• Arin Chandra,
• Michael Peek,
• Ralph Nanan
Published online: October 11, 2012
p2149-2160

Musculoskeletal Pathology

Immune-Mediated Necrotizing Myopathy Is Characterized by a Specific Th1-M1 Polarized Immune Profile
• Corinna Preuße,
• Hans H. Goebel,
• Josephin Held,
• ...
• Arend Koch,
• Frank L. Heppner,
• Werner Stenzel
Published online: October 10, 2012
p2161-2171

Tumorigenesis and Neoplastic Progression

Lipid Raft Association Restricts CD44-Ezrin Interaction and Promotion of Breast Cancer Cell Migration
• Simona Donatello,
• Irina S. Babina,
• Lee D. Hazelwood,
• Arnold D.K. Hill,
• Ivan R. Nabi,
• Ann M. Hopkins
Published online: October 01, 2012
p2172-2187


Epithelial-to-Mesenchymal Transition Leads to Docetaxel Resistance in Prostate Cancer and Is Mediated by Reduced Expression of miR-200c and miR-205
• Martin Puhr,
• Julia Hoefer,
• Georg Schäfer,
• ...
• Isabel Heidegger,
• Hannes Neuwirt,
• Zoran Culig
Published online: October 05, 2012
p2188-2201

TGF-β Signaling, Activated Stromal Fibroblasts, and Cysteine Cathepsins B and L Drive the Invasive Growth of Human Melanoma Cells
• Miao Yin,
• Johanna Soikkeli,
• Tiina Jahkola,
• Susanna Virolainen,
• Olli Saksela,
• Erkki Hölttä
Published online: October 11, 2012
p2202-2216

Vascular Biology, Atherosclerosis, and Endothelium Biology

Topical Simvastatin Accelerates Wound Healing in Diabetes by Enhancing Angiogenesis and Lymphangiogenesis
• Jun Asai,
• Hideya Takenaka,
• Satoshi Hirakawa,
• ...
• Shigeru Kinoshita,
• Yoshiki Tokura,
• Norito Katoh
Published online: November 08, 2012
p2217-2224


Remodeling of the Lymphatic Vasculature during Mouse Mammary Gland Morphogenesis Is Mediated via Epithelial-Derived Lymphangiogenic Stimuli
• Kelly L. Betterman,
• Sophie Paquet-Fifield,
• Marie-Liesse Asselin-Labat,
• ...
• Steven A. Stacker,
• Marc G. Achen,
• Natasha L. Harvey
Published online: October 16, 2012
p2225-2238

E-Selectin Mediates Stem Cell Adhesion and Formation of Blood Vessels in a Murine Model of Infantile Hemangioma
• David M. Smadja,
• John B. Mulliken,
• Joyce Bischoff
Published online: October 08, 2012
p2239-2247